JP2018513983A5 - - Google Patents
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- Publication number
- JP2018513983A5 JP2018513983A5 JP2018503728A JP2018503728A JP2018513983A5 JP 2018513983 A5 JP2018513983 A5 JP 2018513983A5 JP 2018503728 A JP2018503728 A JP 2018503728A JP 2018503728 A JP2018503728 A JP 2018503728A JP 2018513983 A5 JP2018513983 A5 JP 2018513983A5
- Authority
- JP
- Japan
- Prior art keywords
- test
- saliva sample
- progesterone
- estradiol
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000012360 testing method Methods 0.000 claims 46
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 claims 29
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 claims 25
- 210000003296 saliva Anatomy 0.000 claims 22
- 229960005309 estradiol Drugs 0.000 claims 14
- 229960003387 progesterone Drugs 0.000 claims 14
- 239000000186 progesterone Substances 0.000 claims 14
- 239000012491 analyte Substances 0.000 claims 8
- 239000003153 chemical reaction reagent Substances 0.000 claims 8
- 238000000034 method Methods 0.000 claims 8
- 230000035558 fertility Effects 0.000 claims 7
- 102000001706 Immunoglobulin Fab Fragments Human genes 0.000 claims 6
- 108010054477 Immunoglobulin Fab Fragments Proteins 0.000 claims 6
- 239000000463 material Substances 0.000 claims 6
- 238000010606 normalization Methods 0.000 claims 6
- 239000003795 chemical substances by application Substances 0.000 claims 5
- 239000011159 matrix material Substances 0.000 claims 4
- 230000016087 ovulation Effects 0.000 claims 4
- 230000035935 pregnancy Effects 0.000 claims 4
- 229930182833 estradiol Natural products 0.000 claims 3
- 239000007788 liquid Substances 0.000 claims 3
- CZWCKYRVOZZJNM-UHFFFAOYSA-N Prasterone sodium sulfate Natural products C1C(OS(O)(=O)=O)CCC2(C)C3CCC(C)(C(CC4)=O)C4C3CC=C21 CZWCKYRVOZZJNM-UHFFFAOYSA-N 0.000 claims 2
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 claims 2
- 239000002250 absorbent Substances 0.000 claims 2
- 230000002745 absorbent Effects 0.000 claims 2
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 claims 2
- CZWCKYRVOZZJNM-USOAJAOKSA-N dehydroepiandrosterone sulfate Chemical compound C1[C@@H](OS(O)(=O)=O)CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC=C21 CZWCKYRVOZZJNM-USOAJAOKSA-N 0.000 claims 2
- 229940088597 hormone Drugs 0.000 claims 2
- 239000005556 hormone Substances 0.000 claims 2
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 claims 2
- 229950009829 prasterone sulfate Drugs 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 238000011144 upstream manufacturing Methods 0.000 claims 2
- DNXHEGUUPJUMQT-UHFFFAOYSA-N (+)-estrone Natural products OC1=CC=C2C3CCC(C)(C(CC4)=O)C4C3CCC2=C1 DNXHEGUUPJUMQT-UHFFFAOYSA-N 0.000 claims 1
- PROQIPRRNZUXQM-UHFFFAOYSA-N (16alpha,17betaOH)-Estra-1,3,5(10)-triene-3,16,17-triol Natural products OC1=CC=C2C3CCC(C)(C(C(O)C4)O)C4C3CCC2=C1 PROQIPRRNZUXQM-UHFFFAOYSA-N 0.000 claims 1
- 102000009027 Albumins Human genes 0.000 claims 1
- 108010088751 Albumins Proteins 0.000 claims 1
- XUIIKFGFIJCVMT-GFCCVEGCSA-N D-thyroxine Chemical compound IC1=CC(C[C@@H](N)C(O)=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-GFCCVEGCSA-N 0.000 claims 1
- DNXHEGUUPJUMQT-CBZIJGRNSA-N Estrone Chemical compound OC1=CC=C2[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1 DNXHEGUUPJUMQT-CBZIJGRNSA-N 0.000 claims 1
- AUYYCJSJGJYCDS-LBPRGKRZSA-N Thyrolar Chemical compound IC1=CC(C[C@H](N)C(O)=O)=CC(I)=C1OC1=CC=C(O)C(I)=C1 AUYYCJSJGJYCDS-LBPRGKRZSA-N 0.000 claims 1
- 102000011923 Thyrotropin Human genes 0.000 claims 1
- 108010061174 Thyrotropin Proteins 0.000 claims 1
- 102000004338 Transferrin Human genes 0.000 claims 1
- 108090000901 Transferrin Proteins 0.000 claims 1
- AEMFNILZOJDQLW-QAGGRKNESA-N androst-4-ene-3,17-dione Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1 AEMFNILZOJDQLW-QAGGRKNESA-N 0.000 claims 1
- 229960005471 androstenedione Drugs 0.000 claims 1
- AEMFNILZOJDQLW-UHFFFAOYSA-N androstenedione Natural products O=C1CCC2(C)C3CCC(C)(C(CC4)=O)C4C3CCC2=C1 AEMFNILZOJDQLW-UHFFFAOYSA-N 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 229940109239 creatinine Drugs 0.000 claims 1
- FMGSKLZLMKYGDP-USOAJAOKSA-N dehydroepiandrosterone Chemical compound C1[C@@H](O)CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC=C21 FMGSKLZLMKYGDP-USOAJAOKSA-N 0.000 claims 1
- 229960001348 estriol Drugs 0.000 claims 1
- PROQIPRRNZUXQM-ZXXIGWHRSA-N estriol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H]([C@H](O)C4)O)[C@@H]4[C@@H]3CCC2=C1 PROQIPRRNZUXQM-ZXXIGWHRSA-N 0.000 claims 1
- 229960003399 estrone Drugs 0.000 claims 1
- 238000011156 evaluation Methods 0.000 claims 1
- 229960000890 hydrocortisone Drugs 0.000 claims 1
- 238000012125 lateral flow test Methods 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 238000011002 quantification Methods 0.000 claims 1
- 238000004445 quantitative analysis Methods 0.000 claims 1
- 229960003604 testosterone Drugs 0.000 claims 1
- 229940034208 thyroxine Drugs 0.000 claims 1
- XUIIKFGFIJCVMT-UHFFFAOYSA-N thyroxine-binding globulin Natural products IC1=CC(CC([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-UHFFFAOYSA-N 0.000 claims 1
- 239000012581 transferrin Substances 0.000 claims 1
- 229940035722 triiodothyronine Drugs 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021184153A JP7471269B2 (ja) | 2015-04-06 | 2021-11-11 | 唾液試料中の分析物を検出するための試験装置および使用方法 |
| JP2023219181A JP2024038119A (ja) | 2015-04-06 | 2023-12-26 | 唾液試料中の分析物を検出するための試験装置および使用方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562143792P | 2015-04-06 | 2015-04-06 | |
| US62/143,792 | 2015-04-06 | ||
| PCT/US2016/026049 WO2016164365A1 (en) | 2015-04-06 | 2016-04-05 | A test device for detecting an analyte in a saliva sample and method of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021184153A Division JP7471269B2 (ja) | 2015-04-06 | 2021-11-11 | 唾液試料中の分析物を検出するための試験装置および使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018513983A JP2018513983A (ja) | 2018-05-31 |
| JP2018513983A5 true JP2018513983A5 (enExample) | 2019-05-16 |
Family
ID=55754464
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018503728A Pending JP2018513983A (ja) | 2015-04-06 | 2016-04-05 | 唾液試料中の分析物を検出するための試験装置および使用方法 |
| JP2021184153A Active JP7471269B2 (ja) | 2015-04-06 | 2021-11-11 | 唾液試料中の分析物を検出するための試験装置および使用方法 |
| JP2023219181A Pending JP2024038119A (ja) | 2015-04-06 | 2023-12-26 | 唾液試料中の分析物を検出するための試験装置および使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021184153A Active JP7471269B2 (ja) | 2015-04-06 | 2021-11-11 | 唾液試料中の分析物を検出するための試験装置および使用方法 |
| JP2023219181A Pending JP2024038119A (ja) | 2015-04-06 | 2023-12-26 | 唾液試料中の分析物を検出するための試験装置および使用方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20180106799A1 (enExample) |
| EP (1) | EP3281014B1 (enExample) |
| JP (3) | JP2018513983A (enExample) |
| CN (2) | CN115728482A (enExample) |
| BR (1) | BR112017021305A2 (enExample) |
| WO (1) | WO2016164365A1 (enExample) |
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| US11061026B2 (en) | 2017-02-17 | 2021-07-13 | MFB Fertility, Inc. | System of evaluating corpus luteum function by recurrently evaluating progesterone non-serum bodily fluids on multiple days |
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| CN107015006A (zh) * | 2017-03-30 | 2017-08-04 | 北京理工大学 | 一种细胞因子免疫层析试纸及其制备方法 |
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-
2016
- 2016-04-05 US US15/564,731 patent/US20180106799A1/en not_active Abandoned
- 2016-04-05 BR BR112017021305A patent/BR112017021305A2/pt not_active Application Discontinuation
- 2016-04-05 EP EP16716788.1A patent/EP3281014B1/en active Active
- 2016-04-05 JP JP2018503728A patent/JP2018513983A/ja active Pending
- 2016-04-05 CN CN202211315819.8A patent/CN115728482A/zh active Pending
- 2016-04-05 CN CN201680032652.0A patent/CN107667290A/zh active Pending
- 2016-04-05 WO PCT/US2016/026049 patent/WO2016164365A1/en not_active Ceased
-
2021
- 2021-01-28 US US17/160,883 patent/US20210223243A1/en not_active Abandoned
- 2021-11-11 JP JP2021184153A patent/JP7471269B2/ja active Active
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2023
- 2023-12-26 JP JP2023219181A patent/JP2024038119A/ja active Pending
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