JP2018511659A5 - - Google Patents
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- Publication number
- JP2018511659A5 JP2018511659A5 JP2018505505A JP2018505505A JP2018511659A5 JP 2018511659 A5 JP2018511659 A5 JP 2018511659A5 JP 2018505505 A JP2018505505 A JP 2018505505A JP 2018505505 A JP2018505505 A JP 2018505505A JP 2018511659 A5 JP2018511659 A5 JP 2018511659A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- vaccine composition
- adjuvant
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 20
- 229960005486 vaccine Drugs 0.000 claims 20
- 239000002671 adjuvant Substances 0.000 claims 14
- 230000004927 fusion Effects 0.000 claims 13
- 108090000765 processed proteins & peptides Proteins 0.000 claims 13
- 125000003275 alpha amino acid group Chemical group 0.000 claims 12
- 206010028980 Neoplasm Diseases 0.000 claims 6
- 201000011510 cancer Diseases 0.000 claims 6
- 102000014914 Carrier Proteins Human genes 0.000 claims 4
- 108010078791 Carrier Proteins Proteins 0.000 claims 4
- 239000011159 matrix material Substances 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 101150029707 ERBB2 gene Proteins 0.000 claims 3
- 206010006187 Breast cancer Diseases 0.000 claims 2
- 208000026310 Breast neoplasm Diseases 0.000 claims 2
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 2
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims 2
- 206010017758 gastric cancer Diseases 0.000 claims 2
- 230000014509 gene expression Effects 0.000 claims 2
- 230000002018 overexpression Effects 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 201000011549 stomach cancer Diseases 0.000 claims 2
- 108010071134 CRM197 (non-toxic variant of diphtheria toxin) Proteins 0.000 claims 1
- 102000016607 Diphtheria Toxin Human genes 0.000 claims 1
- 108010053187 Diphtheria Toxin Proteins 0.000 claims 1
- 229940076838 Immune checkpoint inhibitor Drugs 0.000 claims 1
- ILRRQNADMUWWFW-UHFFFAOYSA-K aluminium phosphate Chemical compound O1[Al]2OP1(=O)O2 ILRRQNADMUWWFW-UHFFFAOYSA-K 0.000 claims 1
- 229940103272 aluminum potassium sulfate Drugs 0.000 claims 1
- 210000003719 b-lymphocyte Anatomy 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims 1
- 239000012274 immune-checkpoint protein inhibitor Substances 0.000 claims 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims 1
- GRLPQNLYRHEGIJ-UHFFFAOYSA-J potassium aluminium sulfate Chemical compound [Al+3].[K+].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O GRLPQNLYRHEGIJ-UHFFFAOYSA-J 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2015901375A AU2015901375A0 (en) | 2015-04-17 | A vaccine composition and uses thereof | |
| AU2015901375 | 2015-04-17 | ||
| PCT/AU2016/050275 WO2016164980A1 (en) | 2015-04-17 | 2016-04-15 | A vaccine composition and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018511659A JP2018511659A (ja) | 2018-04-26 |
| JP2018511659A5 true JP2018511659A5 (https=) | 2019-05-23 |
| JP6957448B2 JP6957448B2 (ja) | 2021-11-02 |
Family
ID=57125491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018505505A Active JP6957448B2 (ja) | 2015-04-17 | 2016-04-15 | ワクチン組成物およびその使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10532090B2 (https=) |
| EP (1) | EP3283105B1 (https=) |
| JP (1) | JP6957448B2 (https=) |
| KR (1) | KR102372615B1 (https=) |
| CN (1) | CN108025061B (https=) |
| AU (1) | AU2016250289B2 (https=) |
| ES (1) | ES2908071T3 (https=) |
| NZ (1) | NZ736194A (https=) |
| RS (1) | RS63080B1 (https=) |
| RU (1) | RU2726411C2 (https=) |
| SG (1) | SG11201708247XA (https=) |
| TW (1) | TWI740823B (https=) |
| WO (1) | WO2016164980A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210346484A1 (en) * | 2017-12-11 | 2021-11-11 | Medizinische Universitaet Wien | Method of producing a vaccine composition and uses thereof |
| WO2019153042A1 (en) * | 2018-02-07 | 2019-08-15 | Imugene Limited | A vaccine composition and uses thereof |
| US20240027434A1 (en) * | 2020-12-16 | 2024-01-25 | Dynavax Technologies Corporation | Method for quantifying cpg-containing oligonucleotides in compositions comprising alum |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0739984A1 (en) * | 1995-04-26 | 1996-10-30 | San Tumorforschungs-Gmbh | Bivalent polypeptides containing at least two domains |
| GB9808932D0 (en) * | 1998-04-27 | 1998-06-24 | Chiron Spa | Polyepitope carrier protein |
| EP1246597B1 (en) * | 1999-08-03 | 2015-01-14 | The Ohio State University | Polypeptides and polynucleotides for enhancing immune reactivity to her-2 protein |
| EP1236740B1 (de) | 2001-02-28 | 2012-07-18 | Bio Life Science Forschungs- und Entwicklungsges.m.b.H. | Vakzine gegen Krebserkrankungen, die mit dem HER-2/neu Onkogen assoziiert sind |
| US20050008649A1 (en) | 2003-06-02 | 2005-01-13 | University Of Miami | Chimeric molecules and methods of use |
| ES2348312T3 (es) | 2006-04-13 | 2010-12-02 | Bio Life Science Forschungs- Und Entwicklungsges.M.B.H. | Vacuna her-2/neu a base de múltiples péptidos. |
| EP2292258A1 (en) * | 2009-08-18 | 2011-03-09 | Pevion Biotech Ltd. | Multiepitope vaccine for Her2/neu-associated cancers |
| EP2659906A1 (en) * | 2012-05-01 | 2013-11-06 | Affiris AG | Compositions |
| DK2668959T3 (en) * | 2012-05-31 | 2015-01-26 | Innavirvax | Immunogenic compounds comprising HIV gp41 peptide coupled to CRM197 carrier protein |
| EP3166646A4 (en) * | 2014-07-07 | 2018-03-07 | Duke University | Vaccines against an oncogenic isoform of her2 (erbb2) and methods of using the same |
-
2016
- 2016-04-15 RU RU2017137502A patent/RU2726411C2/ru active
- 2016-04-15 KR KR1020177032987A patent/KR102372615B1/ko active Active
- 2016-04-15 JP JP2018505505A patent/JP6957448B2/ja active Active
- 2016-04-15 SG SG11201708247XA patent/SG11201708247XA/en unknown
- 2016-04-15 EP EP16779340.5A patent/EP3283105B1/en active Active
- 2016-04-15 ES ES16779340T patent/ES2908071T3/es active Active
- 2016-04-15 RS RS20220204A patent/RS63080B1/sr unknown
- 2016-04-15 US US15/316,868 patent/US10532090B2/en active Active
- 2016-04-15 NZ NZ736194A patent/NZ736194A/en unknown
- 2016-04-15 WO PCT/AU2016/050275 patent/WO2016164980A1/en not_active Ceased
- 2016-04-15 CN CN201680029118.4A patent/CN108025061B/zh active Active
- 2016-04-15 TW TW105111976A patent/TWI740823B/zh active
- 2016-04-15 AU AU2016250289A patent/AU2016250289B2/en active Active
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