JP2009520758A5 - - Google Patents
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- Publication number
- JP2009520758A5 JP2009520758A5 JP2008546433A JP2008546433A JP2009520758A5 JP 2009520758 A5 JP2009520758 A5 JP 2009520758A5 JP 2008546433 A JP2008546433 A JP 2008546433A JP 2008546433 A JP2008546433 A JP 2008546433A JP 2009520758 A5 JP2009520758 A5 JP 2009520758A5
- Authority
- JP
- Japan
- Prior art keywords
- fragment
- binding domain
- polypeptide
- igg binding
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000002163 immunogen Effects 0.000 claims 15
- 239000012634 fragment Substances 0.000 claims 12
- 229920001184 polypeptide Polymers 0.000 claims 12
- 102000004196 processed proteins & peptides Human genes 0.000 claims 12
- 108090000765 processed proteins & peptides Proteins 0.000 claims 12
- 125000003275 alpha amino acid group Chemical group 0.000 claims 7
- 108090000623 proteins and genes Proteins 0.000 claims 7
- 102000004169 proteins and genes Human genes 0.000 claims 7
- 108091033319 polynucleotide Proteins 0.000 claims 4
- 102000040430 polynucleotide Human genes 0.000 claims 4
- 239000002157 polynucleotide Substances 0.000 claims 4
- 108020001507 fusion proteins Proteins 0.000 claims 3
- 102000037865 fusion proteins Human genes 0.000 claims 3
- 108091026890 Coding region Proteins 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 210000002925 A-like Anatomy 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000005847 immunogenicity Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0526038A GB0526038D0 (en) | 2005-12-21 | 2005-12-21 | Immunogenic composition |
| GB0526038.5 | 2005-12-21 | ||
| PCT/EP2006/069944 WO2007071692A2 (en) | 2005-12-21 | 2006-12-19 | Immunogenic composition |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013117514A Division JP2013215197A (ja) | 2005-12-21 | 2013-06-04 | 免疫原性組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009520758A JP2009520758A (ja) | 2009-05-28 |
| JP2009520758A5 true JP2009520758A5 (https=) | 2010-02-12 |
| JP5780693B2 JP5780693B2 (ja) | 2015-09-16 |
Family
ID=35840898
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008546433A Expired - Fee Related JP5780693B2 (ja) | 2005-12-21 | 2006-12-19 | 免疫原性組成物 |
| JP2013117514A Pending JP2013215197A (ja) | 2005-12-21 | 2013-06-04 | 免疫原性組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013117514A Pending JP2013215197A (ja) | 2005-12-21 | 2013-06-04 | 免疫原性組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20080311146A1 (https=) |
| EP (1) | EP1962890B1 (https=) |
| JP (2) | JP5780693B2 (https=) |
| CA (1) | CA2634898A1 (https=) |
| ES (1) | ES2558703T3 (https=) |
| GB (1) | GB0526038D0 (https=) |
| WO (1) | WO2007071692A2 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0610776D0 (en) * | 2006-05-31 | 2006-07-12 | Univ Bath | Novel applications for staphylococcus aureus Sbi protein |
| EP2099932A4 (en) | 2006-12-06 | 2009-11-18 | Repligen Corp | NUCLEIC ACIDS ENCODING THE RECOMBINANT PROTEIN A |
| HUE026855T2 (en) | 2009-04-03 | 2016-07-28 | Univ Chicago | Compositions and methods related to protein a (spa) variants |
| EP3263128A3 (en) | 2009-04-14 | 2018-01-24 | GlaxoSmithKline Biologicals S.A. | Compositions for immunising against staphylococcus aureus |
| BR112012009014B8 (pt) | 2009-09-30 | 2022-10-04 | Novartis Ag | Processo para preparar conjugado de polissacarídeo capsular de s. aureus tipo 5 ou tipo 8 e molécula de transporte crm197, conjugado e composição imunogênica |
| HUE034251T2 (en) | 2009-10-30 | 2018-02-28 | Glaxosmithkline Biologicals Sa | Purification of staphylococcus aureus type 5 and type 8 capsular saccharides |
| CA2803298C (en) | 2010-07-02 | 2020-07-14 | The University Of Chicago | Compositions and methods related to protein a (spa) variants |
| EP2614074A1 (en) * | 2010-09-09 | 2013-07-17 | The University of Chicago | Methods and compositions involving protective staphylococcal antigens |
| WO2013096948A1 (en) | 2011-12-23 | 2013-06-27 | Lydon Nicholas B | Immunoglobulins and variants directed against pathogenic microbes |
| US9988439B2 (en) | 2011-12-23 | 2018-06-05 | Nicholas B. Lydon | Immunoglobulins and variants directed against pathogenic microbes |
| CN102698260B (zh) * | 2012-04-20 | 2013-09-25 | 西北农林科技大学 | 预防山羊葡萄球菌乳房炎的亚单位疫苗的制备方法及应用 |
| US9974848B2 (en) | 2013-11-14 | 2018-05-22 | Duke University | Tetanus toxoid and CCL3 improve DC vaccines |
| US10195262B2 (en) * | 2013-12-04 | 2019-02-05 | Glaxosmithkline Biologicals S.A. | Prevention of Staphylococcus aureus infections by glycoprotein vaccines synthesized in Escherichia coli |
| CN103694322B (zh) * | 2013-12-09 | 2016-08-17 | 成都欧林生物科技股份有限公司 | 金黄色葡萄球菌SpA5突变体及其制备方法和应用 |
| CN106103469B (zh) | 2014-03-26 | 2020-11-27 | 葛兰素史密丝克莱恩生物有限公司 | 突变型葡萄球菌抗原 |
| GB201619965D0 (en) * | 2016-11-25 | 2017-01-11 | Univ Of Bath The | Immunogenic compositions comprising sbi protein and uses thereof |
| GB201802339D0 (en) | 2018-02-13 | 2018-03-28 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
| US12514914B2 (en) | 2019-05-14 | 2026-01-06 | The University Of Chicago | Methods and compositions comprising Staphylococcus protein a (SpA) variants |
| EP3777884A1 (en) * | 2019-08-15 | 2021-02-17 | GlaxoSmithKline Biologicals S.A. | Immunogenic composition |
| EP4140501A4 (en) * | 2020-04-23 | 2025-06-04 | BrightPath Biotherapeutics Co., Ltd. | IMPROVED PEPTIDE VACCINE |
| WO2024129976A2 (en) * | 2022-12-14 | 2024-06-20 | Scribe Therapeutics Inc. | Particle delivery systems |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5571514A (en) * | 1987-06-01 | 1996-11-05 | Alfa Laval Ab | Fibronectin binding protein as well as its preparation |
| SE9704141D0 (sv) | 1997-11-12 | 1997-11-12 | Sbl Vaccin Ab | New protein and nucleotide sequence, encoding said protein |
| EP1121149A4 (en) | 1998-08-31 | 2002-03-20 | Inhibitex Inc | IMMUNOTHERAPEUTICS AGAINST STAPHYLOCOCCUS USING DONOR SELECTION AND DONOR STIMULATION |
| ES2322409T3 (es) | 1998-08-31 | 2009-06-19 | Inhibitex, Inc. | Vacunas multicomponentes contra staphylococcus aureus. |
| ES2321892T3 (es) | 1998-09-14 | 2009-06-12 | Nabi Biopharmaceuticals | Composiciones de beta-glucanos e inmunoglobulinas especificas. |
| US7098383B2 (en) * | 2000-12-19 | 2006-08-29 | Sembiosys Genetics Inc. | Methods for the production of multimeric immunoglobulins, and related compositions |
| GB0107661D0 (en) * | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
| CA2517439C (en) * | 2003-03-07 | 2013-07-23 | Wyeth Holdings Corporation | Polysaccharide - staphylococcal surface adhesin carrier protein conjugates for immunization against nosocomial infections |
| US20050137220A1 (en) * | 2003-07-23 | 2005-06-23 | Pharmacia Corporation | Beta-carboline compounds and analogues thereof as mitogen-activated protein kinase-activated protein kinase-2 inhibitors |
| KR20060065643A (ko) * | 2003-07-24 | 2006-06-14 | 머크 앤드 캄파니 인코포레이티드 | 스타필로코쿠스 아우레우스에 대한 방어 면역 반응을유도하는 폴리펩타이드 |
| NZ553776A (en) * | 2004-09-22 | 2010-05-28 | Glaxosmithkline Biolog Sa | Immunogenic composition comprising staphylococcal PNAG and Type 5 and/or 8 Capsular polysaccharide or oligosaccharide. |
-
2005
- 2005-12-21 GB GB0526038A patent/GB0526038D0/en not_active Ceased
-
2006
- 2006-12-19 JP JP2008546433A patent/JP5780693B2/ja not_active Expired - Fee Related
- 2006-12-19 CA CA 2634898 patent/CA2634898A1/en not_active Abandoned
- 2006-12-19 US US12/097,820 patent/US20080311146A1/en not_active Abandoned
- 2006-12-19 EP EP06830724.8A patent/EP1962890B1/en active Active
- 2006-12-19 ES ES06830724.8T patent/ES2558703T3/es active Active
- 2006-12-19 WO PCT/EP2006/069944 patent/WO2007071692A2/en not_active Ceased
-
2013
- 2013-06-04 JP JP2013117514A patent/JP2013215197A/ja active Pending
-
2015
- 2015-01-15 US US14/598,221 patent/US20150125481A1/en not_active Abandoned
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