JP2018510628A5 - - Google Patents
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- JP2018510628A5 JP2018510628A5 JP2017547530A JP2017547530A JP2018510628A5 JP 2018510628 A5 JP2018510628 A5 JP 2018510628A5 JP 2017547530 A JP2017547530 A JP 2017547530A JP 2017547530 A JP2017547530 A JP 2017547530A JP 2018510628 A5 JP2018510628 A5 JP 2018510628A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- seq
- cell
- cancer
- mhc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562134253P | 2015-03-17 | 2015-03-17 | |
| GB201504502A GB201504502D0 (en) | 2015-03-17 | 2015-03-17 | Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers |
| GB1504502.4 | 2015-03-17 | ||
| US62/134,253 | 2015-03-17 | ||
| PCT/EP2016/055817 WO2016146751A1 (en) | 2015-03-17 | 2016-03-17 | Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020047156A Division JP6990935B2 (ja) | 2015-03-17 | 2020-03-18 | 膵臓がんおよびその他のがんに対する免疫療法において使用するための新規ペプチドおよびペプチドの組み合わせ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018510628A JP2018510628A (ja) | 2018-04-19 |
| JP2018510628A5 true JP2018510628A5 (enExample) | 2018-06-07 |
| JP6715856B2 JP6715856B2 (ja) | 2020-07-01 |
Family
ID=53016273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017547530A Expired - Fee Related JP6715856B2 (ja) | 2015-03-17 | 2016-03-17 | 膵臓がんおよびその他のがんに対する免疫療法において使用するための新規ペプチドおよびペプチドの組み合わせ |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US10076560B2 (enExample) |
| EP (1) | EP3270952A1 (enExample) |
| JP (1) | JP6715856B2 (enExample) |
| KR (1) | KR102718168B1 (enExample) |
| CN (2) | CN107428810B (enExample) |
| AR (2) | AR121587A2 (enExample) |
| AU (4) | AU2016232140B2 (enExample) |
| BR (1) | BR112017019217A2 (enExample) |
| CA (1) | CA2979506A1 (enExample) |
| CR (3) | CR20170419A (enExample) |
| EA (1) | EA037783B1 (enExample) |
| GB (1) | GB201504502D0 (enExample) |
| MA (3) | MA40713A1 (enExample) |
| MX (1) | MX2017011857A (enExample) |
| PE (1) | PE20171515A1 (enExample) |
| SG (2) | SG10202001404VA (enExample) |
| TW (2) | TWI726872B (enExample) |
| UA (1) | UA123392C2 (enExample) |
| WO (1) | WO2016146751A1 (enExample) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2943565B1 (en) | 2013-01-14 | 2018-03-28 | Fred Hutchinson Cancer Research Center | Compositions and methods for delivery of immune cells to treat un-resectable or non-resected tumor cells and tumor relapse |
| TWI755157B (zh) | 2015-03-17 | 2022-02-11 | 德商英麥提克生物技術股份有限公司 | 用於抗胰臟癌與其他癌症的免疫治療的新穎胜肽及胜肽的組合 |
| US10988543B2 (en) | 2015-11-11 | 2021-04-27 | Opi Vi—Ip Holdco Llc | Humanized anti-tumor necrosis factor alpha receptor 2 (anti-TNFR2) antibodies and methods of use thereof to elicit an immune response against a tumor |
| US20170199961A1 (en) | 2015-12-16 | 2017-07-13 | Gritstone Oncology, Inc. | Neoantigen Identification, Manufacture, and Use |
| GB201604490D0 (en) | 2016-03-16 | 2016-04-27 | Immatics Biotechnologies Gmbh | Peptides combination of peptides for use in immunotherapy against cancers |
| GB201609193D0 (en) | 2016-05-25 | 2016-07-06 | Immatics Biotechnologies Gmbh | Novel peptides, combination of peptides as targets for use in immunotherapy against gallbladder cancer and cholangiocarcinoma and other cancers |
| JP7075125B2 (ja) | 2016-05-25 | 2022-05-25 | イマティクス バイオテクノロジーズ ゲーエムベーハー | 標的としてのおよび胆嚢がんおよび胆管がんおよびその他のがんに対する免疫療法で使用するための新規ペプチド、ペプチド組み合わせ |
| DE102016123893A1 (de) | 2016-12-08 | 2018-06-14 | Immatics Biotechnologies Gmbh | T-Zellrezeptoren mit verbesserter Bindung |
| KR102379955B1 (ko) | 2016-12-08 | 2022-03-29 | 이매틱스 바이오테크놀로지스 게엠베하 | 짝짓기가 향상된 t 세포 수용체 |
| CN110167566A (zh) * | 2016-12-21 | 2019-08-23 | 弗莱德哈钦森癌症研究中心 | 治疗实体瘤细胞和逃避变体的支架 |
| AU2018251839B2 (en) * | 2017-04-10 | 2022-06-30 | Immatics Biotechnologies Gmbh | Peptides and combination thereof for use in the immunotherapy against cancers |
| ES3041991T3 (en) | 2017-05-25 | 2025-11-17 | Leidos Inc | Pd-1 and ctla-4 dual inhibitor peptides |
| DE102017115966A1 (de) | 2017-07-14 | 2019-01-17 | Immatics Biotechnologies Gmbh | Polypeptidmolekül mit verbesserter zweifacher Spezifität |
| US20190016802A1 (en) | 2017-07-14 | 2019-01-17 | Immatics Biotechnologies Gmbh | Dual specificity polypeptide molecule |
| ES3029080T3 (en) | 2017-10-10 | 2025-06-23 | Seattle Project Corp | Neoantigen identification using hotspots |
| US11885815B2 (en) | 2017-11-22 | 2024-01-30 | Gritstone Bio, Inc. | Reducing junction epitope presentation for neoantigens |
| DE102017127984B4 (de) | 2017-11-27 | 2019-12-05 | Immatics US, Inc. | Verfahren für die Vermehrung und Aktivierung von γδ-T-Zellen |
| US11464800B2 (en) * | 2018-02-09 | 2022-10-11 | Immatics US, Inc. | Methods for manufacturing T cells |
| AU2018410849B2 (en) | 2018-02-27 | 2025-02-27 | Leidos, Inc. | PD-1 peptide inhibitors |
| EP3765053A2 (en) * | 2018-03-16 | 2021-01-20 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Antigenic peptides deriving from urocortin 3 and uses thereof for the diagnosis and treatment of type 1 diabetes |
| US12492230B2 (en) * | 2018-03-16 | 2025-12-09 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Antigenic peptides deriving from secretogranin V and uses thereof for the diagnosis and treatment of type 1 diabetes |
| DE102018108612A1 (de) | 2018-03-21 | 2019-09-26 | Immatics US, Inc. | Verfahren zur erhöhung der persistenz von adoptiv infundierten t-zellen |
| TW202039535A (zh) | 2018-12-18 | 2020-11-01 | 德商英麥提克生物技術股份有限公司 | B*08限制肽和肽組合物抗癌免疫治療和相關方法 |
| US20200297768A1 (en) | 2019-03-19 | 2020-09-24 | Immatics US, Inc. | Cd28 t cell cultures, compositions, and methods of using thereof |
| JP7606471B2 (ja) | 2019-05-22 | 2024-12-25 | レイドス, インコーポレイテッド | Lag3結合ペプチド |
| PH12021552979A1 (en) | 2019-05-27 | 2023-10-09 | Immatics Us Inc | Viral vectors and their use in adoptive cellular therapy |
| CN114303060A (zh) | 2019-06-06 | 2022-04-08 | 伊玛提克斯生物技术有限公司 | 使用序列相似肽进行反向选择分选 |
| US20210032370A1 (en) | 2019-08-02 | 2021-02-04 | Immatics Biotechnologies Gmbh | Recruiting agent further binding an mhc molecule |
| IL295891A (en) | 2020-02-24 | 2022-10-01 | Immatics Us Inc | Methods for propagating t cells for the treatment of cancer and related malignancies |
| DE102020111571A1 (de) | 2020-03-11 | 2021-09-16 | Immatics US, Inc. | Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren |
| DE102020106710A1 (de) | 2020-03-11 | 2021-09-16 | Immatics US, Inc. | Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren |
| JP7744928B2 (ja) * | 2020-04-29 | 2025-09-26 | イージー バイオメッド カンパニー リミテッド | 大腸癌の早期検出、治療応答性および予後の予測のための方法 |
| JP7560850B2 (ja) * | 2020-07-01 | 2024-10-03 | 学校法人関西医科大学 | 尿路系上皮腫瘍関連病変を検出するためのバイオマーカー |
| EP4188947A2 (en) | 2020-07-31 | 2023-06-07 | Leidos, Inc. | Lag3 binding peptides |
| US20220056411A1 (en) | 2020-08-21 | 2022-02-24 | Immatics US, Inc. | Methods for isolating cd8+ selected t cells |
| WO2022081426A1 (en) | 2020-10-12 | 2022-04-21 | Leidos, Inc. | Immunomodulatory peptides |
| CN112557347B (zh) * | 2020-11-12 | 2023-10-24 | 渤海大学 | 一种黏液层中乳糜粒子迁移模型的制备及检测方法 |
| CN112462066B (zh) * | 2020-12-03 | 2023-05-19 | 中南大学湘雅医院 | Fam3c蛋白及其特异性抗体在制备检测鼻咽癌试剂盒中的应用、试剂盒及其应用 |
| WO2022147029A2 (en) | 2020-12-31 | 2022-07-07 | Immatics US, Inc. | Cd8 polypeptides, compositions, and methods of using thereof |
| CN112760383B (zh) * | 2021-03-02 | 2023-07-21 | 上海欧易生物医学科技有限公司 | 应用于肺腺癌细胞亚群的一组qRT-PCR内参基因及其应用 |
| CN114163511B (zh) * | 2021-03-24 | 2025-02-25 | 深圳市新靶向生物科技有限公司 | 一种与肝癌驱动基因突变相关的抗原肽组合及其应用 |
| IL308258A (en) | 2021-05-05 | 2024-01-01 | Immatics Biotechnologies Gmbh | Bma031 antigen binding polypeptides |
| JP2024534825A (ja) | 2021-08-24 | 2024-09-26 | イマティクス ユーエス,アイエヌシー. | 条件付きリガンド交換により産生されたペプチドmhc複合体を使用する免疫細胞の選択 |
| TW202332765A (zh) | 2021-09-20 | 2023-08-16 | 美商英麥提克斯股份有限公司 | 用於t細胞療法之t細胞群體的單核球耗盡 |
| CN118541392A (zh) | 2021-09-28 | 2024-08-23 | 准星生物医药有限公司 | 多种形式的分子复合物 |
| US20230192886A1 (en) | 2021-11-08 | 2023-06-22 | Immatics Biotechnologies Gmbh | Adoptive cell therapy combination treatment and compositions thereof |
| KR102618065B1 (ko) * | 2021-12-10 | 2023-12-22 | 성균관대학교산학협력단 | 췌장암 진단용 조성물 및 이를 이용한 췌장암 진단 방법 |
| CN114214406A (zh) * | 2021-12-15 | 2022-03-22 | 天津医科大学总医院 | 一种用于评价肿瘤患者免疫治疗反应性和评估肿瘤预后的三联标志物及其应用 |
| AU2023262596A1 (en) | 2022-04-28 | 2024-12-05 | Immatics US, Inc. | Membrane-bound il-15, cd8 polypeptides, cells, compositions, and methods of using thereof |
| EP4514821A1 (en) | 2022-04-28 | 2025-03-05 | Immatics US, Inc. | Il-12 polypeptides, il-15 polypeptides, il-18 polypeptides, cd8 polypeptides, compositions, and methods of using thereof |
| EP4514834A1 (en) | 2022-04-28 | 2025-03-05 | Immatics US, Inc. | Dominant negative tgfbeta receptor polypeptides, cd8 polypeptides, cells, compositions, and methods of using thereof |
| WO2023215825A1 (en) | 2022-05-05 | 2023-11-09 | Immatics US, Inc. | Methods for improving t cell efficacy |
| WO2025096649A1 (en) | 2023-11-01 | 2025-05-08 | Immatics US, Inc. | Membrane-bound il-15, cd8 polypeptides, cells, compositions, and methods of using thereof |
| CN119724622B (zh) * | 2024-11-25 | 2025-12-12 | 中国人民解放军总医院第五医学中心 | 一种评价ptt对胰腺癌治疗效果的方法、系统及设备 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US5610031A (en) * | 1993-10-27 | 1997-03-11 | The General Hospital Corporation | B1k chain of laminin and methods of use |
| US6316213B1 (en) * | 1997-03-19 | 2001-11-13 | The Board Of Trustees Of The University Of Arkansas | Methods for the early diagnosis of ovarian, breast and lung cancer |
| AU4158799A (en) * | 1998-06-06 | 1999-12-30 | Genostic Pharma Limited | Probes used for genetic filing |
| AU3395900A (en) * | 1999-03-12 | 2000-10-04 | Human Genome Sciences, Inc. | Human lung cancer associated gene sequences and polypeptides |
| WO2001042270A1 (en) * | 1999-12-10 | 2001-06-14 | Epimmune Inc. | Inducing cellular immune responses to carcinoembryonic antigen using peptide and nucleic acid compositions |
| EP1242049A4 (en) * | 1999-12-13 | 2005-01-05 | Epimmune Inc | VACCINE COMPOSITIONS AND ANTIGEN PEPTIDES ASSOCIATED WITH CLASS I HLA-A2 TUMOR |
| CN1469926A (zh) * | 2000-03-29 | 2004-01-21 | 科里克萨有限公司 | 治疗和诊断肺癌的组合物和方法 |
| WO2003010327A2 (en) | 2001-02-21 | 2003-02-06 | Curagen Corporation | Novel proteins and nucleic acids encoding same |
| US20030021796A1 (en) * | 2001-05-04 | 2003-01-30 | Leszek Ignatowicz | Method of enhancing T cell immunity by selection of antigen specific T cells |
| WO2003104428A2 (en) * | 2002-01-21 | 2003-12-18 | Vaccinex, Inc. | Gene differentially expressed in breast and bladder cancer and encoded polypeptides |
| JP2003321494A (ja) * | 2002-02-26 | 2003-11-11 | Daiichi Fine Chemical Co Ltd | プロmmp−7の活性化調節方法 |
| EP1594447A2 (en) * | 2002-10-02 | 2005-11-16 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| AU2003298014A1 (en) * | 2002-12-04 | 2004-06-23 | Diadexus, Inc. | Compositions, splice variants and methods relating to colon specific genes and proteins |
| ES2556232T3 (es) * | 2004-03-31 | 2016-01-14 | International Institute Of Cancer Immunology, Inc. | Péptidos antigénicos del cáncer derivados de WT1 |
| EP1760089B1 (en) * | 2005-09-05 | 2009-08-19 | Immatics Biotechnologies GmbH | Tumor-associated peptides binding to human leukocyte antigen (HLA) class I or II molecules and related anti-cancer vaccine |
| GB0611116D0 (en) * | 2006-06-06 | 2006-07-19 | Oxford Genome Sciences Uk Ltd | Proteins |
| KR101351195B1 (ko) * | 2007-07-27 | 2014-01-14 | 이매틱스 바이오테크놀로지스 게엠베하 | 면역 치료를 위한 새로운 면역원성 에피톱 |
| EP2127664A1 (en) * | 2008-02-15 | 2009-12-02 | Max-Delbrück-Centrum | Change of the load state of MHC molecules by dipeptides |
| CA2718830C (en) * | 2008-03-31 | 2017-04-18 | Kyoto University | Method for proliferation of pluripotent stem cells |
| PL2119726T5 (pl) * | 2008-05-14 | 2018-04-30 | Immatics Biotechnologies Gmbh | Nowe i silne peptydy MHC klasy II pochodzące z surwiwiny i neurokanu |
| US8568996B2 (en) * | 2008-10-21 | 2013-10-29 | University of Pittsburgh—of the Commonwealth System of Higher Education | MMP activation peptide detection in biological samples |
| GB201004551D0 (en) * | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer |
| WO2011119484A1 (en) * | 2010-03-23 | 2011-09-29 | Iogenetics, Llc | Bioinformatic processes for determination of peptide binding |
| WO2013040142A2 (en) * | 2011-09-16 | 2013-03-21 | Iogenetics, Llc | Bioinformatic processes for determination of peptide binding |
| CA2840472A1 (en) * | 2011-06-22 | 2012-12-27 | Oncocyte Corporation | Methods and compositions for the treatment and diagnosis of bladder cancer |
| WO2013033609A2 (en) * | 2011-08-31 | 2013-03-07 | Oncocyte Corporation | Methods and compositions for the treatment and diagnosis of cancer |
| US20140065620A1 (en) * | 2011-12-29 | 2014-03-06 | Mayo Foundation For Medical Education And Research | Nucleic acids for detecting breast cancer |
| TWI714869B (zh) * | 2013-08-05 | 2021-01-01 | 德商伊瑪提克斯生物科技有限公司 | 新穎肽類,細胞及其用於治療多種腫瘤的用途,其製造方法及包含其等之醫藥組成物 |
| CN104163862B (zh) * | 2013-12-04 | 2017-02-08 | 魏敏杰 | 与人mhc‑i类分子结合的grp78多肽表位 |
| CN104306976A (zh) * | 2014-04-26 | 2015-01-28 | 深圳市康尔诺生物技术有限公司 | 一种高效的肿瘤个体化免疫治疗方法及其应用 |
-
2015
- 2015-03-17 GB GB201504502A patent/GB201504502D0/en not_active Ceased
-
2016
- 2016-03-17 CA CA2979506A patent/CA2979506A1/en active Pending
- 2016-03-17 US US15/073,528 patent/US10076560B2/en active Active
- 2016-03-17 KR KR1020177025935A patent/KR102718168B1/ko active Active
- 2016-03-17 MX MX2017011857A patent/MX2017011857A/es unknown
- 2016-03-17 MA MA40713A patent/MA40713A1/fr unknown
- 2016-03-17 CN CN201680015234.0A patent/CN107428810B/zh not_active Expired - Fee Related
- 2016-03-17 MA MA46648A patent/MA46648B2/fr unknown
- 2016-03-17 SG SG10202001404VA patent/SG10202001404VA/en unknown
- 2016-03-17 UA UAA201707771A patent/UA123392C2/uk unknown
- 2016-03-17 WO PCT/EP2016/055817 patent/WO2016146751A1/en not_active Ceased
- 2016-03-17 EA EA201791853A patent/EA037783B1/ru unknown
- 2016-03-17 TW TW105108310A patent/TWI726872B/zh not_active IP Right Cessation
- 2016-03-17 BR BR112017019217-9A patent/BR112017019217A2/pt not_active Application Discontinuation
- 2016-03-17 PE PE2017001485A patent/PE20171515A1/es unknown
- 2016-03-17 CR CR20170419A patent/CR20170419A/es unknown
- 2016-03-17 CN CN202110838669.8A patent/CN113563456A/zh active Pending
- 2016-03-17 MA MA46647A patent/MA46647A1/fr unknown
- 2016-03-17 EP EP16710223.5A patent/EP3270952A1/en active Pending
- 2016-03-17 JP JP2017547530A patent/JP6715856B2/ja not_active Expired - Fee Related
- 2016-03-17 CR CR20210234A patent/CR20210234A/es unknown
- 2016-03-17 TW TW109140068A patent/TWI769586B/zh active
- 2016-03-17 CR CR20210233A patent/CR20210233A/es unknown
- 2016-03-17 SG SG11201706155XA patent/SG11201706155XA/en unknown
- 2016-03-17 AU AU2016232140A patent/AU2016232140B2/en not_active Ceased
-
2018
- 2018-01-12 US US15/869,471 patent/US10357551B2/en active Active
-
2020
- 2020-08-18 AU AU2020220070A patent/AU2020220070B2/en not_active Ceased
- 2020-08-18 AU AU2020220073A patent/AU2020220073B2/en not_active Ceased
- 2020-08-18 AU AU2020220072A patent/AU2020220072B2/en not_active Ceased
-
2021
- 2021-02-24 AR ARP210100472A patent/AR121587A2/es unknown
- 2021-02-24 AR ARP210100473A patent/AR121588A2/es unknown
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