JP2018510628A5 - - Google Patents

Download PDF

Info

Publication number
JP2018510628A5
JP2018510628A5 JP2017547530A JP2017547530A JP2018510628A5 JP 2018510628 A5 JP2018510628 A5 JP 2018510628A5 JP 2017547530 A JP2017547530 A JP 2017547530A JP 2017547530 A JP2017547530 A JP 2017547530A JP 2018510628 A5 JP2018510628 A5 JP 2018510628A5
Authority
JP
Japan
Prior art keywords
peptide
seq
cell
cancer
mhc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017547530A
Other languages
English (en)
Japanese (ja)
Other versions
JP2018510628A (ja
JP6715856B2 (ja
Filing date
Publication date
Priority claimed from GB201504502A external-priority patent/GB201504502D0/en
Application filed filed Critical
Publication of JP2018510628A publication Critical patent/JP2018510628A/ja
Publication of JP2018510628A5 publication Critical patent/JP2018510628A5/ja
Application granted granted Critical
Publication of JP6715856B2 publication Critical patent/JP6715856B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2017547530A 2015-03-17 2016-03-17 膵臓がんおよびその他のがんに対する免疫療法において使用するための新規ペプチドおよびペプチドの組み合わせ Expired - Fee Related JP6715856B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562134253P 2015-03-17 2015-03-17
GB201504502A GB201504502D0 (en) 2015-03-17 2015-03-17 Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers
GB1504502.4 2015-03-17
US62/134,253 2015-03-17
PCT/EP2016/055817 WO2016146751A1 (en) 2015-03-17 2016-03-17 Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020047156A Division JP6990935B2 (ja) 2015-03-17 2020-03-18 膵臓がんおよびその他のがんに対する免疫療法において使用するための新規ペプチドおよびペプチドの組み合わせ

Publications (3)

Publication Number Publication Date
JP2018510628A JP2018510628A (ja) 2018-04-19
JP2018510628A5 true JP2018510628A5 (enExample) 2018-06-07
JP6715856B2 JP6715856B2 (ja) 2020-07-01

Family

ID=53016273

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017547530A Expired - Fee Related JP6715856B2 (ja) 2015-03-17 2016-03-17 膵臓がんおよびその他のがんに対する免疫療法において使用するための新規ペプチドおよびペプチドの組み合わせ

Country Status (19)

Country Link
US (2) US10076560B2 (enExample)
EP (1) EP3270952A1 (enExample)
JP (1) JP6715856B2 (enExample)
KR (1) KR102718168B1 (enExample)
CN (2) CN113563456A (enExample)
AR (2) AR121587A2 (enExample)
AU (4) AU2016232140B2 (enExample)
BR (1) BR112017019217A2 (enExample)
CA (1) CA2979506A1 (enExample)
CR (3) CR20210233A (enExample)
EA (1) EA037783B1 (enExample)
GB (1) GB201504502D0 (enExample)
MA (3) MA40713A1 (enExample)
MX (1) MX2017011857A (enExample)
PE (1) PE20171515A1 (enExample)
SG (2) SG10202001404VA (enExample)
TW (2) TWI726872B (enExample)
UA (1) UA123392C2 (enExample)
WO (1) WO2016146751A1 (enExample)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014110591A1 (en) 2013-01-14 2014-07-17 Fred Hutchinson Cancer Research Center Compositions and methods for delivery of immune cells to treat un-resectable or non-resected tumor cells and tumor relapse
MY190083A (en) 2015-03-17 2022-03-25 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers
CA3004830A1 (en) 2015-11-11 2017-05-18 Opi Vi- Ip Holdco Llc Composition and methods for anti-tnfr2 antibodies
KR102883915B1 (ko) 2015-12-16 2025-11-18 시애틀 프로젝트 코포레이션 신생항원 동정, 제조, 및 용도
GB201604490D0 (en) 2016-03-16 2016-04-27 Immatics Biotechnologies Gmbh Peptides combination of peptides for use in immunotherapy against cancers
GB201609193D0 (en) 2016-05-25 2016-07-06 Immatics Biotechnologies Gmbh Novel peptides, combination of peptides as targets for use in immunotherapy against gallbladder cancer and cholangiocarcinoma and other cancers
JP7075125B2 (ja) 2016-05-25 2022-05-25 イマティクス バイオテクノロジーズ ゲーエムベーハー 標的としてのおよび胆嚢がんおよび胆管がんおよびその他のがんに対する免疫療法で使用するための新規ペプチド、ペプチド組み合わせ
DE102016123893A1 (de) 2016-12-08 2018-06-14 Immatics Biotechnologies Gmbh T-Zellrezeptoren mit verbesserter Bindung
EP4317432A3 (en) 2016-12-08 2024-04-17 Immatics Biotechnologies GmbH T cell receptors with improved pairing
WO2018119274A1 (en) * 2016-12-21 2018-06-28 Fred Hutchinson Cancer Research Center Scaffolds to treat solid tumor cells and escape variants
EP3609530A1 (en) * 2017-04-10 2020-02-19 Immatics Biotechnologies GmbH Peptides and combination thereof for use in the immunotherapy against cancers
EP3630807B1 (en) 2017-05-25 2025-08-13 Leidos, Inc. Pd-1 and ctla-4 dual inhibitor peptides
PT3428194T (pt) 2017-07-14 2021-11-18 Immatics Biotechnologies Gmbh Molécula de polipéptido com especificidade dupla melhorada
DE102017115966A1 (de) 2017-07-14 2019-01-17 Immatics Biotechnologies Gmbh Polypeptidmolekül mit verbesserter zweifacher Spezifität
WO2019075112A1 (en) 2017-10-10 2019-04-18 Gritstone Oncology, Inc. IDENTIFICATION OF NEO-ANTIGENS USING HOT POINTS
KR20260008173A (ko) 2017-11-22 2026-01-15 시애틀 프로젝트 코포레이션 신생항원에 대한 접합 에피토프 제시 감소
DE102017127984B4 (de) 2017-11-27 2019-12-05 Immatics US, Inc. Verfahren für die Vermehrung und Aktivierung von γδ-T-Zellen
JP7470640B2 (ja) * 2018-02-09 2024-04-18 イマティクス ユーエス,アイエヌシー. T細胞を製造する方法
WO2019168524A1 (en) 2018-02-27 2019-09-06 Leidos, Inc. Pd-1 peptide inhibitors
US12098179B2 (en) 2018-03-16 2024-09-24 Inserm (Institut National De La Sante Et De La Recherche Medicale) Antigenic peptides deriving from urocortin 3 and uses thereof for the diagnosis and treatment of type 1 diabetes
US12492230B2 (en) * 2018-03-16 2025-12-09 INSERM (Institut National de la Santé et de la Recherche Médicale) Antigenic peptides deriving from secretogranin V and uses thereof for the diagnosis and treatment of type 1 diabetes
DE102018108612A1 (de) 2018-03-21 2019-09-26 Immatics US, Inc. Verfahren zur erhöhung der persistenz von adoptiv infundierten t-zellen
TW202039535A (zh) * 2018-12-18 2020-11-01 德商英麥提克生物技術股份有限公司 B*08限制肽和肽組合物抗癌免疫治療和相關方法
WO2020191172A1 (en) 2019-03-19 2020-09-24 Immatics US, Inc. Cd28 t cell cultures, compositions, and methods of using thereof
JP7606471B2 (ja) 2019-05-22 2024-12-25 レイドス, インコーポレイテッド Lag3結合ペプチド
MA56036A (fr) 2019-05-27 2022-04-06 Immatics Us Inc Vecteurs viraux et leur utilisation dans une thérapie cellulaire adoptive
US20200384028A1 (en) 2019-06-06 2020-12-10 Immatics Biotechnologies Gmbh Sorting with counter selection using sequence similar peptides
US20210032370A1 (en) 2019-08-02 2021-02-04 Immatics Biotechnologies Gmbh Recruiting agent further binding an mhc molecule
AU2021225817A1 (en) 2020-02-24 2022-10-20 Immatics US, Inc. Methods for expanding T cells for the treatment of cancer and related malignancies
DE102020111571A1 (de) 2020-03-11 2021-09-16 Immatics US, Inc. Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
DE102020106710A1 (de) 2020-03-11 2021-09-16 Immatics US, Inc. Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
PH12022552766A1 (en) * 2020-04-29 2024-05-06 Eg Biomed Co Ltd Method for early detection, prediction of treatment response and prognosis of colorectal cancer
JP7560850B2 (ja) * 2020-07-01 2024-10-03 学校法人関西医科大学 尿路系上皮腫瘍関連病変を検出するためのバイオマーカー
US11578102B2 (en) 2020-07-31 2023-02-14 Leidos, Inc. LAG3 binding peptides
US20220056411A1 (en) 2020-08-21 2022-02-24 Immatics US, Inc. Methods for isolating cd8+ selected t cells
JP2023548662A (ja) 2020-10-12 2023-11-20 レイドス, インコーポレイテッド 免疫調節性ペプチド
CN112557347B (zh) * 2020-11-12 2023-10-24 渤海大学 一种黏液层中乳糜粒子迁移模型的制备及检测方法
CN112462066B (zh) * 2020-12-03 2023-05-19 中南大学湘雅医院 Fam3c蛋白及其特异性抗体在制备检测鼻咽癌试剂盒中的应用、试剂盒及其应用
PE20250846A1 (es) 2020-12-31 2025-03-21 Immatics Us Inc Polipeptidos cd8, composiciones y metodos de uso de estos
CN112760383B (zh) * 2021-03-02 2023-07-21 上海欧易生物医学科技有限公司 应用于肺腺癌细胞亚群的一组qRT-PCR内参基因及其应用
CN114163513B (zh) * 2021-03-24 2025-02-25 深圳市新靶向生物科技有限公司 一种与肝癌驱动基因突变相关的抗原肽组合及其应用
BR112023022975A2 (pt) 2021-05-05 2024-01-23 Immatics Biotechnologies Gmbh Polipeptídeos de ligação ao antígeno bma031 melhorados
JP2024534825A (ja) 2021-08-24 2024-09-26 イマティクス ユーエス,アイエヌシー. 条件付きリガンド交換により産生されたペプチドmhc複合体を使用する免疫細胞の選択
WO2023044488A1 (en) 2021-09-20 2023-03-23 Immatics US, Inc. Monocyte depletion of t cells populations for t-cell therapy
EP4408468A4 (en) 2021-09-28 2025-07-02 Frontaim Biomedicines Inc MULTIPLE FORMATS OF MOLECULAR COMPLEXES
US20230192886A1 (en) 2021-11-08 2023-06-22 Immatics Biotechnologies Gmbh Adoptive cell therapy combination treatment and compositions thereof
KR102618065B1 (ko) * 2021-12-10 2023-12-22 성균관대학교산학협력단 췌장암 진단용 조성물 및 이를 이용한 췌장암 진단 방법
CN114214406A (zh) * 2021-12-15 2022-03-22 天津医科大学总医院 一种用于评价肿瘤患者免疫治疗反应性和评估肿瘤预后的三联标志物及其应用
EP4514834A1 (en) 2022-04-28 2025-03-05 Immatics US, Inc. Dominant negative tgfbeta receptor polypeptides, cd8 polypeptides, cells, compositions, and methods of using thereof
IL316515A (en) 2022-04-28 2024-12-01 Immatics Us Inc Membrane-bound IL15 CD8 proteins, cells, compositions and methods for their use
EP4514821A1 (en) 2022-04-28 2025-03-05 Immatics US, Inc. Il-12 polypeptides, il-15 polypeptides, il-18 polypeptides, cd8 polypeptides, compositions, and methods of using thereof
US20230355678A1 (en) 2022-05-05 2023-11-09 Immatics US, Inc. Methods for improving t cell efficacy
WO2025096649A1 (en) 2023-11-01 2025-05-08 Immatics US, Inc. Membrane-bound il-15, cd8 polypeptides, cells, compositions, and methods of using thereof
WO2026096743A1 (en) 2024-10-30 2026-05-07 Immatics US, Inc. Methods for gamma delta t cells manufacturing
CN119724622B (zh) * 2024-11-25 2025-12-12 中国人民解放军总医院第五医学中心 一种评价ptt对胰腺癌治疗效果的方法、系统及设备

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5610031A (en) * 1993-10-27 1997-03-11 The General Hospital Corporation B1k chain of laminin and methods of use
US6316213B1 (en) * 1997-03-19 2001-11-13 The Board Of Trustees Of The University Of Arkansas Methods for the early diagnosis of ovarian, breast and lung cancer
WO1999064627A2 (en) * 1998-06-06 1999-12-16 Genostic Pharma Limited Probes used for genetic profiling
AU3395900A (en) * 1999-03-12 2000-10-04 Human Genome Sciences, Inc. Human lung cancer associated gene sequences and polypeptides
EP1235848A4 (en) 1999-12-10 2005-02-09 Epimmune Inc INDUCING CELLULAR IMMUNE RESPONSES TO CARCINOEMBRYONIC ANTIGEN USING PEPTIDE AND NUCLEIC ACID-CONTAINING COMPOSITIONS
WO2001041741A1 (en) 1999-12-13 2001-06-14 Epimmune Inc. Hla class i a2 tumor associated antigen peptides and vaccine compositions
CN1469926A (zh) * 2000-03-29 2004-01-21 科里克萨有限公司 治疗和诊断肺癌的组合物和方法
WO2003010327A2 (en) * 2001-02-21 2003-02-06 Curagen Corporation Novel proteins and nucleic acids encoding same
US20030021796A1 (en) * 2001-05-04 2003-01-30 Leszek Ignatowicz Method of enhancing T cell immunity by selection of antigen specific T cells
WO2003104428A2 (en) * 2002-01-21 2003-12-18 Vaccinex, Inc. Gene differentially expressed in breast and bladder cancer and encoded polypeptides
JP2003321494A (ja) * 2002-02-26 2003-11-11 Daiichi Fine Chemical Co Ltd プロmmp−7の活性化調節方法
CA2500687A1 (en) * 2002-10-02 2004-04-15 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
WO2004050858A2 (en) * 2002-12-04 2004-06-17 Diadexus, Inc. Compositions, splice variants and methods relating to colon specific genes and proteins
JP4886507B2 (ja) 2004-03-31 2012-02-29 株式会社癌免疫研究所 Wt1由来の癌抗原ペプチド
EP1760089B1 (en) * 2005-09-05 2009-08-19 Immatics Biotechnologies GmbH Tumor-associated peptides binding to human leukocyte antigen (HLA) class I or II molecules and related anti-cancer vaccine
GB0611116D0 (en) * 2006-06-06 2006-07-19 Oxford Genome Sciences Uk Ltd Proteins
BRPI0813626A2 (pt) * 2007-07-27 2014-12-23 Immatics Biotechnologies Gmbh Epitopos imunogênicos para a imunoterapia
EP2127664A1 (en) * 2008-02-15 2009-12-02 Max-Delbrück-Centrum Change of the load state of MHC molecules by dipeptides
JP5464443B2 (ja) * 2008-03-31 2014-04-09 オリエンタル酵母工業株式会社 多能性幹細胞を増殖させる方法
RS53872B2 (sr) * 2008-05-14 2018-06-29 Immatics Biotechnologies Gmbh Novi i snažni mhc peptidi klase ii izvedeni iz survivina i neurokana
WO2010047938A2 (en) * 2008-10-21 2010-04-29 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Mmp activation peptide detection in biological samples
GB201004551D0 (en) * 2010-03-19 2010-05-05 Immatics Biotechnologies Gmbh NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer
WO2011119484A1 (en) * 2010-03-23 2011-09-29 Iogenetics, Llc Bioinformatic processes for determination of peptide binding
WO2013040142A2 (en) * 2011-09-16 2013-03-21 Iogenetics, Llc Bioinformatic processes for determination of peptide binding
WO2012178087A1 (en) * 2011-06-22 2012-12-27 Oncocyte Corporation Methods and compositions for the treatment and diagnosis of bladder cancer
HK1199099A1 (en) * 2011-08-31 2015-06-19 Oncocyte Corporation Methods and compositions for the treatment and diagnosis of cancer
US20140065620A1 (en) * 2011-12-29 2014-03-06 Mayo Foundation For Medical Education And Research Nucleic acids for detecting breast cancer
TWI777194B (zh) * 2013-08-05 2022-09-11 德商伊瑪提克斯生物科技有限公司 新穎肽類,細胞及其用於治療多種腫瘤的用途,其製造方法及包含其等之醫藥組成物(一)
CN104163862B (zh) * 2013-12-04 2017-02-08 魏敏杰 与人mhc‑i类分子结合的grp78多肽表位
CN104306976A (zh) * 2014-04-26 2015-01-28 深圳市康尔诺生物技术有限公司 一种高效的肿瘤个体化免疫治疗方法及其应用

Similar Documents

Publication Publication Date Title
JP2019510465A5 (enExample)
JP2018529320A5 (enExample)
JP2021168652A5 (enExample)
JP2019502360A5 (enExample)
JP2018511321A5 (enExample)
JP2018520653A5 (enExample)
JP2018509135A5 (enExample)
JP2018536383A5 (enExample)
JP2018518937A5 (enExample)
JP2019506838A5 (enExample)
JP2019511214A5 (enExample)
JP2018519243A5 (enExample)
JP2021514178A5 (enExample)
JP2017502076A5 (enExample)
RU2017137142A (ru) Новые пептиды и комбинации пептидов для применения в иммунотерапии рака легких, в том числе немелкоклеточного рака легких (нмрл) и других видов рака
JP2017525336A5 (enExample)
JP2024099580A5 (enExample)
JP2018521641A5 (enExample)
JP2018518956A5 (enExample)
JP2024041841A5 (enExample)
JP2021535900A5 (enExample)
JP2020530759A5 (enExample)
JP2020191862A5 (enExample)
JP2020198875A5 (enExample)
JP2017524337A5 (enExample)