JP2018504419A5 - - Google Patents
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- JP2018504419A5 JP2018504419A5 JP2017540316A JP2017540316A JP2018504419A5 JP 2018504419 A5 JP2018504419 A5 JP 2018504419A5 JP 2017540316 A JP2017540316 A JP 2017540316A JP 2017540316 A JP2017540316 A JP 2017540316A JP 2018504419 A5 JP2018504419 A5 JP 2018504419A5
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- JP
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- Prior art keywords
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- amino acids
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 18
- 150000001413 amino acids Chemical class 0.000 claims 15
- 239000008194 pharmaceutical composition Substances 0.000 claims 15
- 239000000427 antigen Substances 0.000 claims 11
- 102000036639 antigens Human genes 0.000 claims 11
- 108091007433 antigens Proteins 0.000 claims 11
- 210000001744 T-lymphocyte Anatomy 0.000 claims 9
- 102000043131 MHC class II family Human genes 0.000 claims 5
- 108091054438 MHC class II family Proteins 0.000 claims 5
- 201000006417 multiple sclerosis Diseases 0.000 claims 4
- 210000004027 cell Anatomy 0.000 claims 3
- GOJUJUVQIVIZAV-UHFFFAOYSA-N 2-amino-4,6-dichloropyrimidine-5-carbaldehyde Chemical group NC1=NC(Cl)=C(C=O)C(Cl)=N1 GOJUJUVQIVIZAV-UHFFFAOYSA-N 0.000 claims 2
- 108010076181 Proinsulin Proteins 0.000 claims 2
- 206010012601 diabetes mellitus Diseases 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 230000000069 prophylactic effect Effects 0.000 claims 2
- 210000004899 c-terminal region Anatomy 0.000 claims 1
- 230000001413 cellular effect Effects 0.000 claims 1
- 230000001461 cytolytic effect Effects 0.000 claims 1
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 1
- 230000002163 immunogen Effects 0.000 claims 1
- 210000004976 peripheral blood cell Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1418433.7A GB201418433D0 (en) | 2014-10-17 | 2014-10-17 | Novel immunogenic peptides |
| GB1418433.7 | 2014-10-17 | ||
| PCT/EP2015/074063 WO2016059236A1 (en) | 2014-10-17 | 2015-10-16 | Novel immunogenic peptides |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020016331A Division JP2020079271A (ja) | 2014-10-17 | 2020-02-03 | 新規な免疫原性ペプチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018504419A JP2018504419A (ja) | 2018-02-15 |
| JP2018504419A5 true JP2018504419A5 (enExample) | 2018-11-22 |
| JP6655626B2 JP6655626B2 (ja) | 2020-02-26 |
Family
ID=52013133
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017540316A Active JP6655626B2 (ja) | 2014-10-17 | 2015-10-16 | 新規な免疫原性ペプチド |
| JP2020016331A Pending JP2020079271A (ja) | 2014-10-17 | 2020-02-03 | 新規な免疫原性ペプチド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020016331A Pending JP2020079271A (ja) | 2014-10-17 | 2020-02-03 | 新規な免疫原性ペプチド |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US20180228912A1 (enExample) |
| EP (2) | EP3636666A1 (enExample) |
| JP (2) | JP6655626B2 (enExample) |
| KR (1) | KR102556485B1 (enExample) |
| CN (1) | CN107148427B (enExample) |
| AU (2) | AU2015332621B2 (enExample) |
| BR (1) | BR112017007773A2 (enExample) |
| CA (1) | CA2964426C (enExample) |
| DK (1) | DK3207053T3 (enExample) |
| ES (1) | ES2751605T3 (enExample) |
| GB (1) | GB201418433D0 (enExample) |
| MX (1) | MX374635B (enExample) |
| PL (1) | PL3207053T3 (enExample) |
| PT (1) | PT3207053T (enExample) |
| RU (1) | RU2709711C2 (enExample) |
| WO (1) | WO2016059236A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008017517A1 (en) | 2006-08-11 | 2008-02-14 | Life Sciences Research Partners Vzw | Immunogenic peptides and their use in immune disorders |
| US20120009678A1 (en) | 2008-02-14 | 2012-01-12 | Jean-Marie Saint-Remy | Immunotherapy targeting intracellular pathogens |
| WO2009101205A2 (en) | 2008-02-14 | 2009-08-20 | Life Sciences Research Partners Vzw | Immunogenic control of tumours and tumour cells |
| US10023847B2 (en) | 2010-11-25 | 2018-07-17 | Imnate Sarl | Immunogenic peptides for use in the prevention and/or treatment of infectious diseases, autoimmune diseases, immune responses to allofactors, allergic diseases, tumors, graft rejection and immune responses against viral vectors used for gene therapy or gene vaccination |
| GB201201511D0 (en) | 2012-01-30 | 2012-03-14 | Univ Leuven Kath | Modified epitopes for boosting CD4+ T-cell responses |
| GB201309469D0 (en) | 2013-05-28 | 2013-07-10 | Imcyse Sa | Detection of CD4+ T lymphocytes |
| GB201418433D0 (en) * | 2014-10-17 | 2014-12-03 | Imcyse Sa | Novel immunogenic peptides |
| US10729791B2 (en) | 2015-05-18 | 2020-08-04 | Imcyse Sa | Animal models for evaluating pharmaceutical compounds |
| WO2017040976A1 (en) | 2015-09-02 | 2017-03-09 | Erkki Ruoslahti | Compounds and compositions for targeting brain injuries and methods of use thereof |
| EP3352782B1 (en) | 2015-09-25 | 2021-03-31 | ImCyse SA | Improved methods and compounds for eliminating immune responses to therapeutic agents |
| WO2017182528A1 (en) * | 2016-04-19 | 2017-10-26 | Imcyse Sa | Novel immunogenic cd1d binding peptides |
| JP7102430B2 (ja) * | 2017-03-09 | 2022-07-19 | アンシス・エスア | 糖尿病の治療のためのペプチド及び方法 |
| EP3720503A4 (en) | 2017-12-07 | 2021-09-08 | Sanford Burnham Prebys Medical Discovery Institute | COMPOSITIONS AND METHODS OF TREATMENT OF LESIONS OF THE NERVOUS SYSTEM |
| US20210401976A1 (en) * | 2018-11-12 | 2021-12-30 | Imcyse Sa | Immunogenic peptides with improved oxidoreductase motifs |
| WO2020229703A1 (en) | 2019-05-16 | 2020-11-19 | Imcyse Sa | Immunogenic peptides with an oxidoreductase motif comprising a modified cysteine |
| WO2021105371A1 (en) | 2019-11-27 | 2021-06-03 | Imcyse Sa | Methods for stratifying diabetes patients |
| WO2021144478A2 (en) * | 2020-05-06 | 2021-07-22 | Imcyse Sa | Combination treatment for fumarate-related diseases |
| US20240189404A1 (en) | 2020-05-06 | 2024-06-13 | Imcyse Sa | Immunogenic peptides with extended oxidoreductase motifs |
| AR122023A1 (es) | 2020-05-06 | 2022-08-03 | Imcyse Sa | Péptidos y métodos para el tratamiento de esclerosis múltiple |
| EP4146255A1 (en) * | 2020-05-06 | 2023-03-15 | Imcyse SA | Immunogenic peptides with new oxidoreductase motifs |
| EP3915575A1 (en) * | 2020-05-29 | 2021-12-01 | Imnate Sarl | Vaccine formulations |
| EP4321528A4 (en) * | 2021-04-09 | 2025-04-30 | Ajou University Industry-Academic Cooperation Foundation | PEPTIDE FOR THE PREVENTION OR TREATMENT OF INFLAMMATORY DISEASES |
| IL308571A (en) | 2021-05-26 | 2024-01-01 | Imcyse Sa | Methods of treating or preventing autoimmune diseases |
| WO2022253870A1 (en) | 2021-06-01 | 2022-12-08 | Imcyse Sa | Improved methods of treatment using immunogenic peptides |
| US20240269267A1 (en) * | 2021-06-03 | 2024-08-15 | The Wistar Institute Of Anatomy And Biology | Synthetic dna vaccine immunogenic improvements |
| AR126654A1 (es) | 2021-06-29 | 2023-11-01 | Imcyse Sa | Péptidos y métodos para el tratamiento de neuromielitis óptica |
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| US4599231A (en) | 1984-03-09 | 1986-07-08 | Scripps Clinic And Research Foundation | Synthetic hepatitis B virus vaccine including both T cell and B cell determinants |
| US4886782A (en) | 1987-02-26 | 1989-12-12 | The United States Of America As Represented By The Department Of Health And Human Services | Malarial immunogen |
| US5433948A (en) | 1990-02-13 | 1995-07-18 | Thomas; Wayne R. | Cloning and sequencing of allergens of dermatophagoides (house dust mite) |
| JPH06501260A (ja) | 1990-09-27 | 1994-02-10 | シンテロ ヴァクシーン ディベロップメント ケービー | ヒト免疫不全ウィルスに対する中和抗体の誘発とワクチン接種に用いられるペプチド |
| US7252829B1 (en) | 1998-06-17 | 2007-08-07 | Idm Pharma, Inc. | HLA binding peptides and their uses |
| US5589582A (en) | 1992-10-27 | 1996-12-31 | Biotransplant, Inc. | Polynucleotides en coding porcine cytokines |
| US5633234A (en) | 1993-01-22 | 1997-05-27 | The Johns Hopkins University | Lysosomal targeting of immunogens |
| CN1135181A (zh) | 1993-09-14 | 1996-11-06 | Cytel有限公司 | 使用泛dr结合肽改变免疫应答 |
| US8791237B2 (en) | 1994-11-08 | 2014-07-29 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of non-hodgkins lymphoma |
| US7157089B1 (en) | 1996-11-26 | 2007-01-02 | Stressgen Biotechnologies Corporation | Immune responses using compositions containing stress proteins |
| AU1124499A (en) | 1997-10-28 | 1999-05-17 | Maxygen, Inc. | Human papillomavirus vectors |
| NO315238B1 (no) | 1998-05-08 | 2003-08-04 | Gemvax As | Peptider som stammer fra leserammeforskyvingsmutasjoner i TBF<beta>II- eller BAX-genet, og farmasöytiske sammensetninger inneholdende disse,nukleinsyresekvenser som koder for slike peptider, plasmider og virusvektoreromfattende slikenukleinsy |
| US20030152581A1 (en) | 1998-07-30 | 2003-08-14 | Jean-Marie Saint-Remy | Compound and method for the prevention and/or the treatment of allergy |
| AR020102A1 (es) | 1998-07-30 | 2002-04-10 | Ucb Sa | Compuesto para la prevencion y/o tratamiento de la alergia; composicion farmaceutica, composicion cosmetica, composicion en forma de bebida, alimento y/oalimento para animales domesticos que lo comprende y uso de dicho compuesto o dicha composicion farmaceutica para la fabricacion de un alimento |
| US6656471B1 (en) | 1998-11-17 | 2003-12-02 | Board Of Regents, The University Of Texas System | HIV-specific T-cell induction |
| US7780882B2 (en) | 1999-02-22 | 2010-08-24 | Georgetown University | Simplified and improved method for preparing an antibody or an antibody fragment targeted immunoliposome for systemic administration of a therapeutic or diagnostic agent |
| WO2001055393A2 (en) | 2000-01-28 | 2001-08-02 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Mhc class ii restricted t cell epitopes from the cancer antigen ny-eso-1 |
| GB0006437D0 (en) | 2000-03-17 | 2000-05-10 | Leuven Res & Dev Vzw | Compounds for the modulation of allergen sensitivity by antigens sharing T cell epitopes with allergens |
| US20030104570A1 (en) | 2000-06-26 | 2003-06-05 | Cabezon Silva Teresa Elisa Virginia | Triple fusion proteins comprising ubiquitin fused between thioredoxin and a polypeptide of interest |
| US7049413B2 (en) | 2001-05-18 | 2006-05-23 | Ludwig Institute For Cancer Research | MAGE-A3 peptides presented by HLA class II molecules |
| EP1409650B1 (en) | 2001-05-30 | 2006-04-12 | Fondazione Telethon | Ex-vivo isolated cd25+cd4+ t cells with immunosuppressive activity and uses thereof |
| AU2002333865B2 (en) | 2001-10-03 | 2006-02-23 | Unilever Plc | Carbohydrate binding domain containing fusion proteins for delivery of therapeutic and other agents, and compositions containing them |
| US20100183652A1 (en) | 2002-02-21 | 2010-07-22 | Mark Page | STABILIZED HBc CHIMER PARTICLES AS THERAPEUTIC VACCINE FOR CHRONIC HEPATITIS |
| AU2003215395A1 (en) | 2002-02-21 | 2003-09-09 | Apovia, Inc. | STABILIZED HBc CHIMER PARTICLES HAVING MENINGOCCOCAL IMMUNOGENS |
| EP2267023B1 (en) | 2002-09-12 | 2015-02-11 | Oncotherapy Science, Inc. | KDR peptides and vaccines comprising the same |
| WO2005012502A2 (en) | 2003-03-28 | 2005-02-10 | Idm Pharma, Inc. | Methods of identifying optimal variants of peptide epitopes |
| US7651855B2 (en) | 2003-04-17 | 2010-01-26 | The Trustees Of The University Of Pennsylvania | Regulatory T cells and their use in immunotherapy and suppression of autoimmune responses |
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| GB0324265D0 (en) | 2003-10-16 | 2003-11-19 | Medical Res Council | Peptide |
| WO2005042575A2 (en) | 2003-10-30 | 2005-05-12 | Pharmexa A/S | Method for down-regulation of vegf |
| KR20070056042A (ko) | 2004-06-17 | 2007-05-31 | 맨카인드 코포레이션 | 에피토프 유사체 |
| US8252893B2 (en) | 2005-01-31 | 2012-08-28 | Board Of Trustees Of The University Of Arkansas | CD8 T cell epitopes in HPV 16 E6 and E7 proteins and uses thereof |
| US8486411B2 (en) | 2005-08-30 | 2013-07-16 | Children's Hospital & Research Center At Oakland | Methods for identifying an epitope of a polypeptide, chlamydial antigenic polypeptides identified thereby, and methods of use thereof |
| US10183986B2 (en) | 2005-12-15 | 2019-01-22 | Industrial Technology Research Institute | Trimeric collagen scaffold antibodies |
| GB0603081D0 (en) | 2006-02-15 | 2006-03-29 | Dynal Biotech Asa Oslo | Method |
| WO2007135684A2 (en) | 2006-05-22 | 2007-11-29 | Hadasit Medical Research Services & Development Limited | Method of treatment of anti-cd4 autoimmunity |
| WO2008017517A1 (en) | 2006-08-11 | 2008-02-14 | Life Sciences Research Partners Vzw | Immunogenic peptides and their use in immune disorders |
| EP2158211B1 (en) | 2007-05-31 | 2016-08-10 | Medigene AG | Mutated structural protein of a parvovirus |
| WO2009042215A2 (en) | 2007-09-27 | 2009-04-02 | The Board Of Trustees Of The University Of Arkansas | Inhibition of dendritic cell-driven regulatory t cell activation and potentiation of tumor antigen-specific t cell responses by interleukin-15 and map kinase inhibitor |
| EP2050814A1 (en) * | 2007-10-17 | 2009-04-22 | Txcell | Compositions for treating multiple sclerosis |
| WO2009101204A2 (en) | 2008-02-14 | 2009-08-20 | Life Sciences Research Partners Vzw | Elimination of immune responses to viral vectors |
| EP2245059B1 (en) | 2008-02-14 | 2017-09-20 | Life Sciences Research Partners VZW | Cd4+ t-cells with cytolytic properties |
| WO2009100505A1 (en) * | 2008-02-14 | 2009-08-20 | Life Sciences Research Partners Vzw | Immunogenic peptides and their use in transplantati |
| US20120009678A1 (en) | 2008-02-14 | 2012-01-12 | Jean-Marie Saint-Remy | Immunotherapy targeting intracellular pathogens |
| WO2009101205A2 (en) | 2008-02-14 | 2009-08-20 | Life Sciences Research Partners Vzw | Immunogenic control of tumours and tumour cells |
| WO2009101206A2 (en) | 2008-02-14 | 2009-08-20 | Life Sciences Research Partners Vzw | Strategies to prevent and/or treat immune responses to soluble allofactors |
| WO2009106073A2 (en) | 2008-02-28 | 2009-09-03 | Dako Denmark A/S | Mhc multimers in borrelia diagnostics and disease |
| KR101022649B1 (ko) | 2008-08-07 | 2011-03-22 | 삼성모바일디스플레이주식회사 | 헤테로고리 화합물 및 이를 이용한 유기 전계 발광 장치 |
| US9764012B2 (en) | 2009-04-01 | 2017-09-19 | University Of Miami | Vaccine compositions and methods of use thereof |
| JP5942296B2 (ja) | 2010-03-29 | 2016-06-29 | サントル・ナショナル・ドゥ・ラ・ルシェルシュ・シャンティフィクＣｅｎｔｒｅ Ｎａｔｉｏｎａｌ Ｄｅ Ｌａ Ｒｅｃｈｅｒｃｈｅ Ｓｃｉｅｎｔｉｆｉｑｕｅ | 少なくとも１つのｃｘｘｃモチーフを含むポリペプチドと異種抗原とを含む医薬組成物、及びその使用 |
| US10023847B2 (en) | 2010-11-25 | 2018-07-17 | Imnate Sarl | Immunogenic peptides for use in the prevention and/or treatment of infectious diseases, autoimmune diseases, immune responses to allofactors, allergic diseases, tumors, graft rejection and immune responses against viral vectors used for gene therapy or gene vaccination |
| GB201201511D0 (en) * | 2012-01-30 | 2012-03-14 | Univ Leuven Kath | Modified epitopes for boosting CD4+ T-cell responses |
| CA2864432A1 (en) | 2012-02-15 | 2013-08-22 | Ecole Polytechnique Federale De Lausanne | Erythrocyte-binding therapeutics |
| HK1206786A1 (en) * | 2012-04-30 | 2016-01-15 | 英塞斯股份有限公司 | Methods for induction of antigen-specific regulatory t cells |
| GB201309469D0 (en) | 2013-05-28 | 2013-07-10 | Imcyse Sa | Detection of CD4+ T lymphocytes |
| GB201319160D0 (en) | 2013-10-30 | 2013-12-11 | Imcyse Sa | Methods for induction of antigen-specific regulatory t cells |
| SG10201803780UA (en) | 2013-11-04 | 2018-06-28 | Uti Lp | Methods and compositions for sustained immunotherapy |
| GB201418433D0 (en) | 2014-10-17 | 2014-12-03 | Imcyse Sa | Novel immunogenic peptides |
| US10729791B2 (en) | 2015-05-18 | 2020-08-04 | Imcyse Sa | Animal models for evaluating pharmaceutical compounds |
| EP3352782B1 (en) | 2015-09-25 | 2021-03-31 | ImCyse SA | Improved methods and compounds for eliminating immune responses to therapeutic agents |
| WO2017182528A1 (en) | 2016-04-19 | 2017-10-26 | Imcyse Sa | Novel immunogenic cd1d binding peptides |
| JP7102430B2 (ja) | 2017-03-09 | 2022-07-19 | アンシス・エスア | 糖尿病の治療のためのペプチド及び方法 |
| US20210401976A1 (en) | 2018-11-12 | 2021-12-30 | Imcyse Sa | Immunogenic peptides with improved oxidoreductase motifs |
| WO2020229703A1 (en) | 2019-05-16 | 2020-11-19 | Imcyse Sa | Immunogenic peptides with an oxidoreductase motif comprising a modified cysteine |
-
2014
- 2014-10-17 GB GBGB1418433.7A patent/GB201418433D0/en not_active Ceased
-
2015
- 2015-10-16 ES ES15787917T patent/ES2751605T3/es active Active
- 2015-10-16 PT PT157879172T patent/PT3207053T/pt unknown
- 2015-10-16 US US15/516,045 patent/US20180228912A1/en not_active Abandoned
- 2015-10-16 MX MX2017004780A patent/MX374635B/es active IP Right Grant
- 2015-10-16 JP JP2017540316A patent/JP6655626B2/ja active Active
- 2015-10-16 DK DK15787917T patent/DK3207053T3/da active
- 2015-10-16 EP EP19192582.5A patent/EP3636666A1/en not_active Withdrawn
- 2015-10-16 RU RU2017111657A patent/RU2709711C2/ru active
- 2015-10-16 PL PL15787917T patent/PL3207053T3/pl unknown
- 2015-10-16 CA CA2964426A patent/CA2964426C/en active Active
- 2015-10-16 BR BR112017007773-6A patent/BR112017007773A2/pt active Search and Examination
- 2015-10-16 KR KR1020177012944A patent/KR102556485B1/ko active Active
- 2015-10-16 CN CN201580056434.6A patent/CN107148427B/zh active Active
- 2015-10-16 AU AU2015332621A patent/AU2015332621B2/en active Active
- 2015-10-16 WO PCT/EP2015/074063 patent/WO2016059236A1/en not_active Ceased
- 2015-10-16 EP EP15787917.2A patent/EP3207053B1/en active Active
-
2019
- 2019-10-17 AU AU2019250206A patent/AU2019250206A1/en not_active Abandoned
-
2020
- 2020-02-03 JP JP2020016331A patent/JP2020079271A/ja active Pending
- 2020-06-04 US US16/892,588 patent/US12023384B2/en active Active
-
2024
- 2024-05-24 US US18/674,092 patent/US20240342297A1/en active Pending
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