DK3207053T3 - Hidtil ukendte immunogene peptider - Google Patents
Hidtil ukendte immunogene peptider Download PDFInfo
- Publication number
- DK3207053T3 DK3207053T3 DK15787917T DK15787917T DK3207053T3 DK 3207053 T3 DK3207053 T3 DK 3207053T3 DK 15787917 T DK15787917 T DK 15787917T DK 15787917 T DK15787917 T DK 15787917T DK 3207053 T3 DK3207053 T3 DK 3207053T3
- Authority
- DK
- Denmark
- Prior art keywords
- immunogenic peptides
- new immunogenic
- new
- peptides
- immunogenic
- Prior art date
Links
- 230000002163 immunogen Effects 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/64—Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Rehabilitation Therapy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1418433.7A GB201418433D0 (en) | 2014-10-17 | 2014-10-17 | Novel immunogenic peptides |
PCT/EP2015/074063 WO2016059236A1 (en) | 2014-10-17 | 2015-10-16 | Novel immunogenic peptides |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3207053T3 true DK3207053T3 (da) | 2019-11-04 |
Family
ID=52013133
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK15787917T DK3207053T3 (da) | 2014-10-17 | 2015-10-16 | Hidtil ukendte immunogene peptider |
Country Status (16)
Country | Link |
---|---|
US (2) | US20180228912A1 (da) |
EP (2) | EP3636666A1 (da) |
JP (2) | JP6655626B2 (da) |
KR (1) | KR102556485B1 (da) |
CN (1) | CN107148427B (da) |
AU (2) | AU2015332621B2 (da) |
BR (1) | BR112017007773A2 (da) |
CA (1) | CA2964426C (da) |
DK (1) | DK3207053T3 (da) |
ES (1) | ES2751605T3 (da) |
GB (1) | GB201418433D0 (da) |
MX (1) | MX2017004780A (da) |
PL (1) | PL3207053T3 (da) |
PT (1) | PT3207053T (da) |
RU (1) | RU2709711C2 (da) |
WO (1) | WO2016059236A1 (da) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9249202B2 (en) | 2006-08-11 | 2016-02-02 | Life Sciences Research Partners Vzw | Immunogenic peptides and their use in immune disorders |
CA2715611C (en) | 2008-02-14 | 2018-03-13 | Life Sciences Research Partners Vzw | Immunotherapy targeting intracellular pathogens |
US8999346B2 (en) | 2008-02-14 | 2015-04-07 | Life Sciences Research Partners Vzw | Immunogenic control of tumours and tumour cells |
HUE055070T2 (hu) | 2010-11-25 | 2021-10-28 | Imnate Sarl | Immunogén peptidek fertõzõ betegségek, autoimmun betegségek, allofaktorokra adott immunválaszok, allergiás betegségek, tumorok, graftkilökõdés, és génterápiához vagy génvakcinációhoz alkalmazott vírusvektorokkal szembeni immunválaszok megelõzésében és/vagy kezelésében történõ alkalmazásra |
GB201201511D0 (en) | 2012-01-30 | 2012-03-14 | Univ Leuven Kath | Modified epitopes for boosting CD4+ T-cell responses |
GB201309469D0 (en) | 2013-05-28 | 2013-07-10 | Imcyse Sa | Detection of CD4+ T lymphocytes |
GB201418433D0 (en) | 2014-10-17 | 2014-12-03 | Imcyse Sa | Novel immunogenic peptides |
US10729791B2 (en) | 2015-05-18 | 2020-08-04 | Imcyse Sa | Animal models for evaluating pharmaceutical compounds |
WO2017040976A1 (en) | 2015-09-02 | 2017-03-09 | Erkki Ruoslahti | Compounds and compositions for targeting brain injuries and methods of use thereof |
AU2016328582B2 (en) | 2015-09-25 | 2022-11-24 | Imcyse Sa | Improved methods and compounds for eliminating immune responses to therapeutic agents |
AU2017252192C1 (en) | 2016-04-19 | 2023-06-08 | Imcyse Sa | Novel immunogenic CD1d binding peptides |
PE20191529A1 (es) * | 2017-03-09 | 2019-10-23 | Imcyse Sa | Peptidos y metodos para el tratamiento de diabetes |
CN111683685A (zh) | 2017-12-07 | 2020-09-18 | 桑福德伯纳姆普雷比医学发现研究所 | 治疗神经系统损伤的组合物和方法 |
US20210401976A1 (en) * | 2018-11-12 | 2021-12-30 | Imcyse Sa | Immunogenic peptides with improved oxidoreductase motifs |
US20230113747A1 (en) | 2019-05-16 | 2023-04-13 | Imcyse Sa | Immunogenic peptides with an oxidoreductase motif comprising a modified cysteine |
JP2023503630A (ja) | 2019-11-27 | 2023-01-31 | アンシス・エスア | 糖尿病患者を階層化する方法 |
JP2023525079A (ja) * | 2020-05-06 | 2023-06-14 | アンシス・エスア | フマレート関連疾患の併用療法 |
CA3181635A1 (en) | 2020-05-06 | 2021-11-11 | Imcyse Sa | Immunogenic peptides with new oxidoreductase motifs |
US20230340061A1 (en) | 2020-05-06 | 2023-10-26 | Imcyse Sa | Peptides and methods for the treatment of multiple sclerosis |
EP4146254A1 (en) | 2020-05-06 | 2023-03-15 | Imcyse SA | Immunogenic peptides with extended oxidoreductase motifs |
EP3915575A1 (en) * | 2020-05-29 | 2021-12-01 | Imnate Sarl | Vaccine formulations |
WO2022215961A1 (ko) * | 2021-04-09 | 2022-10-13 | 아주대학교산학협력단 | 염증질환 예방 또는 치료용 펩타이드 |
MX2023013971A (es) | 2021-05-26 | 2023-12-11 | Imcyse Sa | Metodos para tratar o prevenir enfermedades autoinmunes. |
EP4347020A1 (en) | 2021-06-01 | 2024-04-10 | Imcyse SA | Improved methods of treatment using immunogenic peptides |
US20240269267A1 (en) * | 2021-06-03 | 2024-08-15 | The Wistar Institute Of Anatomy And Biology | Synthetic dna vaccine immunogenic improvements |
AR126654A1 (es) | 2021-06-29 | 2023-11-01 | Imcyse Sa | Péptidos y métodos para el tratamiento de neuromielitis óptica |
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WO2009042215A2 (en) | 2007-09-27 | 2009-04-02 | The Board Of Trustees Of The University Of Arkansas | Inhibition of dendritic cell-driven regulatory t cell activation and potentiation of tumor antigen-specific t cell responses by interleukin-15 and map kinase inhibitor |
EP2050814A1 (en) * | 2007-10-17 | 2009-04-22 | Txcell | Compositions for treating multiple sclerosis |
EP2249864B1 (en) | 2008-02-14 | 2016-05-04 | Life Sciences Research Partners VZW | Strategies to prevent and/or treat immune responses to soluble allofactors |
WO2009101204A2 (en) | 2008-02-14 | 2009-08-20 | Life Sciences Research Partners Vzw | Elimination of immune responses to viral vectors |
WO2009101207A1 (en) | 2008-02-14 | 2009-08-20 | Life Sciences Research Partners Vzw | Cd4+ t-cells with cytolytic properties |
ES2626115T3 (es) | 2008-02-14 | 2017-07-24 | Life Sciences Research Partners Vzw | Péptidos inmunogénicos y su uso en trasplante |
US8999346B2 (en) | 2008-02-14 | 2015-04-07 | Life Sciences Research Partners Vzw | Immunogenic control of tumours and tumour cells |
CA2715611C (en) | 2008-02-14 | 2018-03-13 | Life Sciences Research Partners Vzw | Immunotherapy targeting intracellular pathogens |
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KR101022649B1 (ko) | 2008-08-07 | 2011-03-22 | 삼성모바일디스플레이주식회사 | 헤테로고리 화합물 및 이를 이용한 유기 전계 발광 장치 |
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HUE055070T2 (hu) | 2010-11-25 | 2021-10-28 | Imnate Sarl | Immunogén peptidek fertõzõ betegségek, autoimmun betegségek, allofaktorokra adott immunválaszok, allergiás betegségek, tumorok, graftkilökõdés, és génterápiához vagy génvakcinációhoz alkalmazott vírusvektorokkal szembeni immunválaszok megelõzésében és/vagy kezelésében történõ alkalmazásra |
GB201201511D0 (en) | 2012-01-30 | 2012-03-14 | Univ Leuven Kath | Modified epitopes for boosting CD4+ T-cell responses |
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JP2015518376A (ja) * | 2012-04-30 | 2015-07-02 | イムシス・ソシエテ・アノニムImcyse Sa | 抗原特異的な調節性t細胞を誘導するための方法 |
GB201309469D0 (en) | 2013-05-28 | 2013-07-10 | Imcyse Sa | Detection of CD4+ T lymphocytes |
GB201319160D0 (en) | 2013-10-30 | 2013-12-11 | Imcyse Sa | Methods for induction of antigen-specific regulatory t cells |
EP3065771B1 (en) | 2013-11-04 | 2019-03-20 | UTI Limited Partnership | Methods and compositions for sustained immunotherapy |
GB201418433D0 (en) | 2014-10-17 | 2014-12-03 | Imcyse Sa | Novel immunogenic peptides |
US10729791B2 (en) | 2015-05-18 | 2020-08-04 | Imcyse Sa | Animal models for evaluating pharmaceutical compounds |
AU2016328582B2 (en) | 2015-09-25 | 2022-11-24 | Imcyse Sa | Improved methods and compounds for eliminating immune responses to therapeutic agents |
AU2017252192C1 (en) | 2016-04-19 | 2023-06-08 | Imcyse Sa | Novel immunogenic CD1d binding peptides |
PE20191529A1 (es) | 2017-03-09 | 2019-10-23 | Imcyse Sa | Peptidos y metodos para el tratamiento de diabetes |
US20210401976A1 (en) | 2018-11-12 | 2021-12-30 | Imcyse Sa | Immunogenic peptides with improved oxidoreductase motifs |
US20230113747A1 (en) | 2019-05-16 | 2023-04-13 | Imcyse Sa | Immunogenic peptides with an oxidoreductase motif comprising a modified cysteine |
-
2014
- 2014-10-17 GB GBGB1418433.7A patent/GB201418433D0/en not_active Ceased
-
2015
- 2015-10-16 WO PCT/EP2015/074063 patent/WO2016059236A1/en active Application Filing
- 2015-10-16 CN CN201580056434.6A patent/CN107148427B/zh active Active
- 2015-10-16 EP EP19192582.5A patent/EP3636666A1/en not_active Withdrawn
- 2015-10-16 PL PL15787917T patent/PL3207053T3/pl unknown
- 2015-10-16 BR BR112017007773-6A patent/BR112017007773A2/pt active Search and Examination
- 2015-10-16 DK DK15787917T patent/DK3207053T3/da active
- 2015-10-16 EP EP15787917.2A patent/EP3207053B1/en active Active
- 2015-10-16 AU AU2015332621A patent/AU2015332621B2/en active Active
- 2015-10-16 KR KR1020177012944A patent/KR102556485B1/ko active IP Right Grant
- 2015-10-16 JP JP2017540316A patent/JP6655626B2/ja active Active
- 2015-10-16 MX MX2017004780A patent/MX2017004780A/es active IP Right Grant
- 2015-10-16 PT PT157879172T patent/PT3207053T/pt unknown
- 2015-10-16 US US15/516,045 patent/US20180228912A1/en not_active Abandoned
- 2015-10-16 RU RU2017111657A patent/RU2709711C2/ru active
- 2015-10-16 ES ES15787917T patent/ES2751605T3/es active Active
- 2015-10-16 CA CA2964426A patent/CA2964426C/en active Active
-
2019
- 2019-10-17 AU AU2019250206A patent/AU2019250206A1/en not_active Abandoned
-
2020
- 2020-02-03 JP JP2020016331A patent/JP2020079271A/ja active Pending
- 2020-06-04 US US16/892,588 patent/US12023384B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
GB201418433D0 (en) | 2014-12-03 |
KR102556485B1 (ko) | 2023-07-17 |
WO2016059236A1 (en) | 2016-04-21 |
BR112017007773A2 (pt) | 2018-01-16 |
PT3207053T (pt) | 2019-11-15 |
CN107148427A (zh) | 2017-09-08 |
US12023384B2 (en) | 2024-07-02 |
AU2015332621A1 (en) | 2017-04-13 |
KR20170069266A (ko) | 2017-06-20 |
EP3636666A1 (en) | 2020-04-15 |
AU2015332621B2 (en) | 2019-07-18 |
EP3207053B1 (en) | 2019-08-21 |
US20200397911A1 (en) | 2020-12-24 |
ES2751605T3 (es) | 2020-04-01 |
MX2017004780A (es) | 2017-11-30 |
RU2709711C2 (ru) | 2019-12-19 |
PL3207053T3 (pl) | 2020-05-18 |
RU2017111657A3 (da) | 2019-05-29 |
US20180228912A1 (en) | 2018-08-16 |
EP3207053A1 (en) | 2017-08-23 |
CA2964426C (en) | 2023-01-24 |
JP2020079271A (ja) | 2020-05-28 |
CA2964426A1 (en) | 2016-04-21 |
RU2017111657A (ru) | 2018-11-19 |
JP6655626B2 (ja) | 2020-02-26 |
JP2018504419A (ja) | 2018-02-15 |
AU2019250206A1 (en) | 2019-11-07 |
CN107148427B (zh) | 2021-08-13 |
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