JP2018502576A5 - - Google Patents

Download PDF

Info

Publication number
JP2018502576A5
JP2018502576A5 JP2017535834A JP2017535834A JP2018502576A5 JP 2018502576 A5 JP2018502576 A5 JP 2018502576A5 JP 2017535834 A JP2017535834 A JP 2017535834A JP 2017535834 A JP2017535834 A JP 2017535834A JP 2018502576 A5 JP2018502576 A5 JP 2018502576A5
Authority
JP
Japan
Prior art keywords
cells
cell population
population
rpe
differentiated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017535834A
Other languages
English (en)
Japanese (ja)
Other versions
JP6882981B2 (ja
JP2018502576A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IL2015/051269 external-priority patent/WO2016108239A1/en
Publication of JP2018502576A publication Critical patent/JP2018502576A/ja
Publication of JP2018502576A5 publication Critical patent/JP2018502576A5/ja
Priority to JP2021012746A priority Critical patent/JP7608192B2/ja
Application granted granted Critical
Publication of JP6882981B2 publication Critical patent/JP6882981B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2017535834A 2014-12-30 2015-12-30 Rpe細胞集団およびそれを作製する方法 Active JP6882981B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021012746A JP7608192B2 (ja) 2014-12-30 2021-01-29 Rpe細胞集団およびそれを作製する方法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201462097753P 2014-12-30 2014-12-30
US62/097,753 2014-12-30
US201562116972P 2015-02-17 2015-02-17
US62/116,972 2015-02-17
US201562195309P 2015-07-22 2015-07-22
US62/195,309 2015-07-22
PCT/IL2015/051269 WO2016108239A1 (en) 2014-12-30 2015-12-30 Rpe cell populations and methods of generating same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021012746A Division JP7608192B2 (ja) 2014-12-30 2021-01-29 Rpe細胞集団およびそれを作製する方法

Publications (3)

Publication Number Publication Date
JP2018502576A JP2018502576A (ja) 2018-02-01
JP2018502576A5 true JP2018502576A5 (enExample) 2019-02-14
JP6882981B2 JP6882981B2 (ja) 2021-06-02

Family

ID=55315463

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2017535834A Active JP6882981B2 (ja) 2014-12-30 2015-12-30 Rpe細胞集団およびそれを作製する方法
JP2021012746A Active JP7608192B2 (ja) 2014-12-30 2021-01-29 Rpe細胞集団およびそれを作製する方法
JP2023010056A Pending JP2023052646A (ja) 2014-12-30 2023-01-26 Rpe細胞集団およびそれを作製する方法
JP2025076125A Pending JP2025111765A (ja) 2014-12-30 2025-05-01 Rpe細胞集団およびそれを作製する方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2021012746A Active JP7608192B2 (ja) 2014-12-30 2021-01-29 Rpe細胞集団およびそれを作製する方法
JP2023010056A Pending JP2023052646A (ja) 2014-12-30 2023-01-26 Rpe細胞集団およびそれを作製する方法
JP2025076125A Pending JP2025111765A (ja) 2014-12-30 2025-05-01 Rpe細胞集団およびそれを作製する方法

Country Status (17)

Country Link
US (6) US11891622B2 (enExample)
EP (2) EP3240892B9 (enExample)
JP (4) JP6882981B2 (enExample)
KR (1) KR20170115514A (enExample)
CN (1) CN107406830A (enExample)
AU (3) AU2015373050B2 (enExample)
BR (1) BR112017014345A2 (enExample)
CA (1) CA2972575A1 (enExample)
DK (1) DK3240892T5 (enExample)
EA (1) EA201791416A1 (enExample)
ES (1) ES2774456T3 (enExample)
HK (1) HK1246348A1 (enExample)
IL (4) IL305070B2 (enExample)
MX (1) MX2017008737A (enExample)
PH (1) PH12017501218A1 (enExample)
SG (1) SG11201705379VA (enExample)
WO (1) WO2016108239A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2501802A4 (en) 2009-11-17 2013-08-21 Advanced Cell Tech Inc METHOD FOR PRODUCING HUMAN RPE CELLS AND PHARMACEUTICAL PREPARATIONS FROM HUMAN RPE CELLS
KR102514912B1 (ko) 2014-12-30 2023-03-27 셀 큐어 뉴로사이언시스 리미티드 망막 질환의 치료 방법
JP2018502575A (ja) 2014-12-30 2018-02-01 セル キュア ニューロサイエンシズ リミテッド 網膜色素上皮細胞集団の評価法
IL305070B2 (en) 2014-12-30 2025-11-01 Cell Cure Neurosciences Ltd Rpe cell populations and methods of generating same
US11090337B2 (en) 2015-08-05 2021-08-17 Cell Cure Neurosciences Ltd Preparation of photoreceptors for the treatment of retinal diseases
DK3331994T3 (da) 2015-08-05 2022-11-21 Cell Cure Neurosciences Ltd Fremstilling af retinale pigmentepitelceller
CA3056653A1 (en) * 2017-03-16 2018-09-20 Lineage Cell Therapeutics, Inc. Methods for the treatment of retinal diseases
CN109957545A (zh) 2017-12-26 2019-07-02 江苏艾尔康生物医药科技有限公司 一种消化rpe细胞的方法
CN111741735A (zh) 2017-12-29 2020-10-02 细胞治疗神经科学有限公司 视网膜色素上皮细胞组合物
EP3969570A1 (en) * 2019-05-15 2022-03-23 Novo Nordisk A/S Methods for obtaining eye field progenitor cells from human pluripotent stem cells
CN111972399B (zh) * 2020-08-06 2021-11-30 温州医科大学 维持肝细胞活性的保存液
MX2024001213A (es) 2021-07-28 2024-03-14 Lineage Cell Therapeutics Inc Expansion de celulas del epitelio pigmentario retiniano.
CN115840045B (zh) * 2023-02-23 2023-04-28 中国农业大学 一种猪胚胎期毛囊基板前体细胞的鉴定方法及其应用

Family Cites Families (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154600B (nl) 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
NL154599B (nl) 1970-12-28 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
US3901654A (en) 1971-06-21 1975-08-26 Biological Developments Receptor assays of biologically active compounds employing biologically specific receptors
US3853987A (en) 1971-09-01 1974-12-10 W Dreyer Immunological reagent and radioimmuno assay
US3867517A (en) 1971-12-21 1975-02-18 Abbott Lab Direct radioimmunoassay for antigens and their antibodies
NL171930C (nl) 1972-05-11 1983-06-01 Akzo Nv Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen.
US3850578A (en) 1973-03-12 1974-11-26 H Mcconnell Process for assaying for biologically active molecules
US3935074A (en) 1973-12-17 1976-01-27 Syva Company Antibody steric hindrance immunoassay with two antibodies
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4034074A (en) 1974-09-19 1977-07-05 The Board Of Trustees Of Leland Stanford Junior University Universal reagent 2-site immunoradiometric assay using labelled anti (IgG)
US3984533A (en) 1975-11-13 1976-10-05 General Electric Company Electrophoretic method of detecting antigen-antibody reaction
US4098876A (en) 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
US4879219A (en) 1980-09-19 1989-11-07 General Hospital Corporation Immunoassay utilizing monoclonal high affinity IgM antibodies
US5011771A (en) 1984-04-12 1991-04-30 The General Hospital Corporation Multiepitopic immunometric assay
US4666828A (en) 1984-08-15 1987-05-19 The General Hospital Corporation Test for Huntington's disease
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4801531A (en) 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
US5272057A (en) 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
SG49267A1 (en) 1989-08-14 1998-05-18 Photogenesis Inc Surgical instrument and cell isolation and transplantation
US5192659A (en) 1989-08-25 1993-03-09 Genetype Ag Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
US6045791A (en) 1992-03-06 2000-04-04 Photogenesis, Inc. Retinal pigment epithelium transplantation
US5281521A (en) 1992-07-20 1994-01-25 The Trustees Of The University Of Pennsylvania Modified avidin-biotin technique
US5405742A (en) 1993-07-16 1995-04-11 Cyromedical Sciences, Inc. Solutions for tissue preservation and bloodless surgery and methods using same
US5755785A (en) 1994-08-12 1998-05-26 The University Of South Florida Sutureless corneal transplantation method
US5843780A (en) 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
US5854015A (en) 1995-10-31 1998-12-29 Applied Food Biotechnology, Inc. Method of making pure 3R-3'R stereoisomer of zeaxanthin for human ingestion
US5941250A (en) 1996-11-21 1999-08-24 University Of Louisville Research Foundation Inc. Retinal tissue implantation method
US6090622A (en) 1997-03-31 2000-07-18 The Johns Hopkins School Of Medicine Human embryonic pluripotent germ cells
GB9715584D0 (en) 1997-07-23 1997-10-01 Eisai Co Ltd Compounds
US6632666B2 (en) 2000-01-14 2003-10-14 Biolife Solutions, Inc. Normothermic, hypothermic and cryopreservation maintenance and storage of cells, tissues and organs in gel-based media
GB0001930D0 (en) 2000-01-27 2000-03-22 Novartis Ag Organic compounds
JP2004520386A (ja) 2001-01-31 2004-07-08 ファイザー・プロダクツ・インク Pde4アイソザイムの阻害剤として有用なニコチンアミドビアリール誘導体
WO2003068233A1 (en) 2002-02-11 2003-08-21 Pfizer Limited Nicotinamide derivatives and a tiotropium salt in combination for the treatment of e.g. inflammatory, allergic and respiratory diseases
US6921633B2 (en) 2002-11-18 2005-07-26 Biolife Solutions Incorporated Methods and compositions for the preservation of cells, tissues or organs in the vitreous state
US7288658B2 (en) 2003-07-15 2007-10-30 Hoffmann-La Roche Inc. Process for preparation of pyridine derivatives
US7794704B2 (en) 2004-01-23 2010-09-14 Advanced Cell Technology, Inc. Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration
WO2006040763A2 (en) 2004-10-12 2006-04-20 Technion Research & Development Foundation Ltd. Isolated primate embryonic cells and methods of generating and using same
EP2410043A3 (en) 2004-12-29 2013-01-23 Hadasit Medical Research Services And Development Ltd. Stem cells culture systems
US20080003676A1 (en) 2006-06-26 2008-01-03 Millipore Corporation Growth of embryonic stem cells
JP5441099B2 (ja) 2007-01-18 2014-03-12 独立行政法人理化学研究所 視細胞への分化誘導方法
US8956866B2 (en) 2007-04-18 2015-02-17 Hadasit Medical Research Services And Development Ltd. Retinal pigment epithelial cells differentiated from embryonic stem cells with nicotinamide and activin A
EP2214646B1 (en) 2007-10-05 2021-06-23 Wayne State University Dendrimers for sustained release of compounds
CN104946591A (zh) 2007-10-12 2015-09-30 奥卡塔治疗公司 制备rpe 细胞和rpe 细胞的组合物的改良方法
US20090226955A1 (en) 2007-12-21 2009-09-10 University Of Miami Immortalized retinal pigmented epithelial cells
JP2009180811A (ja) 2008-01-29 2009-08-13 Canon Inc レンズ鏡筒および撮像装置
KR101025880B1 (ko) 2008-10-23 2011-03-30 공희숙 성체 줄기세포를 이용한 인슐린 분비세포로의 분화 유도방법
SG175880A1 (en) 2009-05-20 2011-12-29 Cardio3 Biosciences Sa Parmaceutical composition for the treatment of heart diseases.
EP2501802A4 (en) * 2009-11-17 2013-08-21 Advanced Cell Tech Inc METHOD FOR PRODUCING HUMAN RPE CELLS AND PHARMACEUTICAL PREPARATIONS FROM HUMAN RPE CELLS
AU2011352154A1 (en) 2010-12-30 2013-07-18 Anthrogenesis Corporation Methods for cryopreserving and encapsulating cells
US20120258451A1 (en) 2011-04-08 2012-10-11 Advanced Cell Technology, Inc. Laser isolation of viable cells
WO2012149484A2 (en) 2011-04-29 2012-11-01 University Of Southern California Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate
EP2709672B1 (en) 2011-05-18 2019-12-18 The Regents of The University of California Compositions and methods for treating retinal diseases
IL287381B2 (en) 2011-11-14 2024-04-01 Astellas Inst For Regenerative Medicine Pharmaceutical preparations of human rpe cells and uses thereof
CA2863172C (en) 2012-01-31 2022-05-03 Cell Cure Neurosciences Ltd. Methods of selecting retinal pigmented epithelial cells
US9850463B2 (en) * 2012-02-01 2017-12-26 The Regents Of The University Of California Methods of culturing retinal pigmented epithelium cells, including xeno-free production, RPE enrichment, and cryopreservation
CN102618497B (zh) * 2012-03-15 2013-10-02 中国人民解放军第三军医大学第一附属医院 利用人骨髓间充质干细胞制备视网膜色素上皮细胞的方法
JP6450673B2 (ja) 2012-04-03 2019-01-09 リニューロン・リミテッドReNeuron Limited 幹細胞微粒子
EP2854884A1 (en) 2012-05-30 2015-04-08 Neurotech USA, Inc. Cryopreserved implantable cell culture devices and uses thereof
ES2688019T3 (es) 2012-06-05 2018-10-30 The Regents Of The University Of California Métodos y composiciones para la producción acelerada de células epiteliales pigmentadas retinianas a partir de células pluripotentes
US9254287B2 (en) 2012-06-11 2016-02-09 Macuclear, Inc. Therapeutic formulation and methods of treatment
PT2925856T (pt) 2012-12-03 2018-06-15 Biolamina Ab Métodos de produção de células epr
EP2951290B1 (en) 2013-02-01 2017-11-29 The United States of America, as represented by The Secretary, Department of Health and Human Services Method for generating retinal pigment epithelium (rpe) cells from induced pluripotent stem cells (ipscs)
US9943545B2 (en) 2013-03-15 2018-04-17 Fate Therapeutics, Inc. Stem cell culture media and methods of enhancing cell survival
BR112016012129A8 (pt) * 2013-12-11 2020-05-12 Pfizer Ltd métodos para produção, expansão e purificação de células epiteliais do pigmento da retina, composição farmacêutica e uso das células
SG11201604994UA (en) 2013-12-20 2016-07-28 Essential Pharmaceuticals Llc Media for cell culture
WO2015175504A1 (en) 2014-05-12 2015-11-19 The Johns Hopkins University Differentiation of human pluripotent stem cells into retinal pigment epithelium using hif1 inhibitors
EP3142485B1 (en) 2014-05-12 2021-04-28 Roosterbio, Inc. Ready-to-print cells and integrated devices
IL305070B2 (en) 2014-12-30 2025-11-01 Cell Cure Neurosciences Ltd Rpe cell populations and methods of generating same
KR102514912B1 (ko) 2014-12-30 2023-03-27 셀 큐어 뉴로사이언시스 리미티드 망막 질환의 치료 방법
JP2018502575A (ja) 2014-12-30 2018-02-01 セル キュア ニューロサイエンシズ リミテッド 網膜色素上皮細胞集団の評価法
JP7055095B2 (ja) 2015-07-29 2022-04-15 ハダシット メディカル リサーチ サービシーズ アンド ディベロップメント リミテッド 網膜色素上皮細胞の大規模生産
US11090337B2 (en) 2015-08-05 2021-08-17 Cell Cure Neurosciences Ltd Preparation of photoreceptors for the treatment of retinal diseases
DK3331994T3 (da) 2015-08-05 2022-11-21 Cell Cure Neurosciences Ltd Fremstilling af retinale pigmentepitelceller
SG10201913250SA (en) 2015-08-18 2020-03-30 Astellas Inst For Regenerative Medicine Clinical formulations
CN105284787A (zh) 2015-10-23 2016-02-03 深圳爱生再生医学科技有限公司 骨髓间充质干细胞的保存试剂及其应用
HRP20250311T1 (hr) 2015-10-26 2025-07-18 Cell Cure Neurosciences Ltd. Priprema stanica pigmentnog epitela mrežnice
KR101982801B1 (ko) 2015-10-28 2019-05-30 서울대학교 산학협력단 망막색소상피 분화 유도용 조성물
CA3056653A1 (en) 2017-03-16 2018-09-20 Lineage Cell Therapeutics, Inc. Methods for the treatment of retinal diseases
CN111741735A (zh) 2017-12-29 2020-10-02 细胞治疗神经科学有限公司 视网膜色素上皮细胞组合物
TWI853255B (zh) 2021-06-09 2024-08-21 美商譜系細胞治療公司 治療視網膜疾病及病況之方法及組成物

Similar Documents

Publication Publication Date Title
JP2024038460A (ja) 網膜変性疾患治療のための改良された様式
JP2024023611A (ja) 網膜疾患を治療する方法
KR101849329B1 (ko) Rpe 세포의 개선된 생산 방법 및 rpe 세포의 조성물
JP7608192B2 (ja) Rpe細胞集団およびそれを作製する方法
JP2022033871A (ja) 網膜色素上皮細胞の調製法
AU2023200036B2 (en) Assessing retinal pigment epithelial cell populations
JP2015091272A5 (enExample)
JP2012024100A (ja) 網膜の変性疾患の処置のための改良されたモーダリティー
JP2018531048A6 (ja) 網膜色素上皮細胞の調製法
JP2017532954A5 (enExample)
CN108795842B (zh) 一种3D悬浮诱导iPS细胞生成自体黑素细胞的方法及应用
AU2016303632A1 (en) Preparation of retinal pigment epithelium cells
JP2020505945A (ja) 奇形腫の形成が抑制された多分化能性幹細胞由来の神経前駆体球の製造方法
JP2024513912A (ja) ドーパミン作動性前駆細胞(precursor cell)及び使用方法
US20090016999A1 (en) Embryonic cell compositions for wound treatment
CN115811980A (zh) 用于治疗视网膜疾病和病况的方法和组合物
Chen et al. Optimization of ex vivo expansion of limbal epithelial progenitors by maintaining native niche cells on denuded amniotic membrane
Mariappan et al. Enriched cultures of retinal cells from BJNhem20 human embryonic stem cell line of Indian origin
Ma et al. Human amniotic fluid stem cells support undifferentiated propagation and pluripotency of human embryonic stem cell without b-FGF in a density dependent manner
CN109312301B (zh) 用于制备培养上皮细胞片的方法
Rohani et al. Embryonic stem cell sphere: a controlled method for production of mouse embryonic stem cell aggregates for differentiation
Chatterji et al. Ocular stem cells to treat retinal and corneal disorders
Ladan Espandar et al. Adult corneal stem cells and alternative sources for regenerative therapy for the cornea
Mathews et al. Standardizing transdifferentiation of rabbit bone marrow mesenchymal stem cells to corneal lineage by simulating corneo-limbal cues. J
Marongiu et al. Amniotic epithelial stem cells in regenerative medicine