JP2018500044A5 - - Google Patents
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- JP2018500044A5 JP2018500044A5 JP2017535710A JP2017535710A JP2018500044A5 JP 2018500044 A5 JP2018500044 A5 JP 2018500044A5 JP 2017535710 A JP2017535710 A JP 2017535710A JP 2017535710 A JP2017535710 A JP 2017535710A JP 2018500044 A5 JP2018500044 A5 JP 2018500044A5
- Authority
- JP
- Japan
- Prior art keywords
- passage
- substance
- solid
- injecting
- inner diameter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000007787 solid Substances 0.000 claims 12
- 239000000126 substance Substances 0.000 claims 12
- 238000000034 method Methods 0.000 claims 7
- 238000004519 manufacturing process Methods 0.000 claims 5
- 239000011521 glass Substances 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 229920005989 resin Polymers 0.000 claims 2
- 239000011347 resin Substances 0.000 claims 2
- 229920005992 thermoplastic resin Polymers 0.000 claims 2
- 229920001187 thermosetting polymer Polymers 0.000 claims 2
- 238000002834 transmittance Methods 0.000 claims 2
- 230000001678 irradiating effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2014-0191302 | 2014-12-28 | ||
| KR20140191302 | 2014-12-28 | ||
| KR10-2015-0178130 | 2015-12-14 | ||
| KR1020150178130A KR102428463B1 (ko) | 2014-12-28 | 2015-12-14 | 세포에 물질을 주입하는 장치 및 제조 방법 |
| PCT/KR2015/014292 WO2016108526A1 (en) | 2014-12-28 | 2015-12-24 | Device for putting material into cell |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018500044A JP2018500044A (ja) | 2018-01-11 |
| JP2018500044A5 true JP2018500044A5 (enExample) | 2019-02-07 |
| JP6883517B2 JP6883517B2 (ja) | 2021-06-09 |
Family
ID=56502546
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017535710A Active JP6883517B2 (ja) | 2014-12-28 | 2015-12-24 | 細胞に物質を注入する装置および製造方法（Ｄｅｖｉｃｅ ｆｏｒ Ｐｕｔｔｉｎｇ Ｍａｔｅｒｉａｌ ｉｎｔｏ Ｃｅｌｌ） |
| JP2017535711A Active JP6805152B2 (ja) | 2014-12-28 | 2015-12-24 | 細胞に物質を注入して細胞を変換させる方法｛Ｍｅｔｈｏｄ ｆｏｒ Ｍｏｄｉｆｙｉｎｇ ａ Ｃｅｌｌ ｂｙ Ｐｕｔｔｉｎｇ Ｍａｔｅｒｉａｌ ｉｎｔｏ ｔｈｅ Ｃｅｌｌ｝ |
| JP2017535708A Pending JP2018504110A (ja) | 2014-12-28 | 2015-12-24 | 運搬体の使用なしで細胞に物質を注入して変換させた細胞（Ｍｏｄｉｆｉｅｄ Ｃｅｌｌ ｂｙ Ｐｕｔｔｉｎｇ Ｍａｔｅｒｉａｌ ｉｎｔｏ ｔｈｅ Ｃｅｌｌ ｗｉｔｈｏｕｔ Ｕｓｉｎｇ Ｖｅｈｉｃｌｅ）［発明の詳細な説明］ |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017535711A Active JP6805152B2 (ja) | 2014-12-28 | 2015-12-24 | 細胞に物質を注入して細胞を変換させる方法｛Ｍｅｔｈｏｄ ｆｏｒ Ｍｏｄｉｆｙｉｎｇ ａ Ｃｅｌｌ ｂｙ Ｐｕｔｔｉｎｇ Ｍａｔｅｒｉａｌ ｉｎｔｏ ｔｈｅ Ｃｅｌｌ｝ |
| JP2017535708A Pending JP2018504110A (ja) | 2014-12-28 | 2015-12-24 | 運搬体の使用なしで細胞に物質を注入して変換させた細胞（Ｍｏｄｉｆｉｅｄ Ｃｅｌｌ ｂｙ Ｐｕｔｔｉｎｇ Ｍａｔｅｒｉａｌ ｉｎｔｏ ｔｈｅ Ｃｅｌｌ ｗｉｔｈｏｕｔ Ｕｓｉｎｇ Ｖｅｈｉｃｌｅ）［発明の詳細な説明］ |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20160272961A1 (enExample) |
| JP (3) | JP6883517B2 (enExample) |
| KR (3) | KR102428463B1 (enExample) |
| DK (1) | DK3037518T3 (enExample) |
| ES (1) | ES2808828T3 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3037518B1 (en) | 2014-12-28 | 2020-05-06 | Femtobiomed Inc. | Device for putting material into cell |
| CN108251268A (zh) * | 2016-12-29 | 2018-07-06 | 上海新微技术研发中心有限公司 | 一种基因转染器及基因转染方法 |
| JP2020530979A (ja) | 2017-06-30 | 2020-11-05 | インスクリプタ， インコーポレイテッド | 自動細胞処理方法、モジュール、機器及びシステム |
| US10738327B2 (en) | 2017-08-28 | 2020-08-11 | Inscripta, Inc. | Electroporation cuvettes for automation |
| JP6985508B2 (ja) | 2017-09-30 | 2021-12-22 | インスクリプタ， インコーポレイテッド | フロースルーエレクトロポレーション機器編成 |
| US10443031B1 (en) | 2018-03-29 | 2019-10-15 | Inscripta, Inc. | Methods for controlling the growth of prokaryotic and eukaryotic cells |
| WO2019200004A1 (en) | 2018-04-13 | 2019-10-17 | Inscripta, Inc. | Automated cell processing instruments comprising reagent cartridges |
| US10557216B2 (en) | 2018-04-24 | 2020-02-11 | Inscripta, Inc. | Automated instrumentation for production of T-cell receptor peptide libraries |
| WO2019209926A1 (en) | 2018-04-24 | 2019-10-31 | Inscripta, Inc. | Automated instrumentation for production of peptide libraries |
| US10858761B2 (en) | 2018-04-24 | 2020-12-08 | Inscripta, Inc. | Nucleic acid-guided editing of exogenous polynucleotides in heterologous cells |
| CA3108767A1 (en) | 2018-06-30 | 2020-01-02 | Inscripta, Inc. | Instruments, modules, and methods for improved detection of edited sequences in live cells |
| US11142740B2 (en) | 2018-08-14 | 2021-10-12 | Inscripta, Inc. | Detection of nuclease edited sequences in automated modules and instruments |
| US10752874B2 (en) | 2018-08-14 | 2020-08-25 | Inscripta, Inc. | Instruments, modules, and methods for improved detection of edited sequences in live cells |
| US10532324B1 (en) | 2018-08-14 | 2020-01-14 | Inscripta, Inc. | Instruments, modules, and methods for improved detection of edited sequences in live cells |
| WO2020081149A2 (en) | 2018-08-30 | 2020-04-23 | Inscripta, Inc. | Improved detection of nuclease edited sequences in automated modules and instruments |
| KR102129681B1 (ko) * | 2018-10-22 | 2020-07-02 | 부경대학교 산학협력단 | 연속공정식 액적 전기천공 장치 및 이를 이용한 연속공정식 액적 전기천공 방법 |
| WO2020101254A1 (ko) * | 2018-11-12 | 2020-05-22 | 주식회사 펨토바이오메드 | 세포 내 물질 전달을 제어하는 방법 및 장치 |
| WO2020252215A1 (en) | 2019-06-12 | 2020-12-17 | Cellfe, Inc. | Methods and systems for cell labeling and imaging |
| US10907125B2 (en) | 2019-06-20 | 2021-02-02 | Inscripta, Inc. | Flow through electroporation modules and instrumentation |
| WO2020257395A1 (en) | 2019-06-21 | 2020-12-24 | Inscripta, Inc. | Genome-wide rationally-designed mutations leading to enhanced lysine production in e. coli |
| US10927385B2 (en) | 2019-06-25 | 2021-02-23 | Inscripta, Inc. | Increased nucleic-acid guided cell editing in yeast |
| US10689669B1 (en) | 2020-01-11 | 2020-06-23 | Inscripta, Inc. | Automated multi-module cell processing methods, instruments, and systems |
| US11225674B2 (en) | 2020-01-27 | 2022-01-18 | Inscripta, Inc. | Electroporation modules and instrumentation |
| JP7824650B2 (ja) * | 2020-03-10 | 2026-03-05 | ハインツテック株式会社 | 複合ナノチューブを介した細胞内物質導入および抽出技術 |
| US20210332388A1 (en) | 2020-04-24 | 2021-10-28 | Inscripta, Inc. | Compositions, methods, modules and instruments for automated nucleic acid-guided nuclease editing in mammalian cells |
| US11787841B2 (en) | 2020-05-19 | 2023-10-17 | Inscripta, Inc. | Rationally-designed mutations to the thrA gene for enhanced lysine production in E. coli |
| CA3201944A1 (en) | 2020-11-18 | 2022-05-27 | Cellfe, Inc. | Methods and systems for mechanoporation-based payload delivery into biological cells |
| US12227729B2 (en) | 2020-12-24 | 2025-02-18 | Cellfe, Inc. | Methods and systems for high-throughput cell processing |
| GB202206443D0 (en) * | 2022-05-03 | 2022-06-15 | Ttp Plc | Apparatus and method |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08322548A (ja) * | 1995-05-31 | 1996-12-10 | Nikon Corp | 細胞操作方法および細胞操作装置 |
| US6027488A (en) * | 1998-06-03 | 2000-02-22 | Genetronics, Inc. | Flow-through electroporation system for ex vivo gene therapy |
| SE0003841D0 (sv) * | 2000-10-20 | 2000-10-20 | Daniel Chiu | A method and apparatus for penetration of lipid bilayer membranes |
| CA2468424A1 (en) * | 2001-11-27 | 2003-06-05 | Cecilia Farre | A method for combined parallel agent delivery and electroporation for cell structures and use thereof |
| JP4530991B2 (ja) * | 2003-04-11 | 2010-08-25 | 独立行政法人理化学研究所 | マイクロインジェクション方法および装置 |
| US7338796B1 (en) * | 2003-08-13 | 2008-03-04 | Sandia Corporation | Vesicle-based method and apparatus for collecting, manipulating, and chemically processing trace macromolecular species |
| US20050170510A1 (en) * | 2003-12-08 | 2005-08-04 | Yong Huang | Device and method for controlled electroporation and molecular delivery into cells and tissue |
| JP2005278480A (ja) * | 2004-03-29 | 2005-10-13 | Fujitsu Ltd | 物質導入装置及び物質導入用チップ |
| US20080248575A1 (en) * | 2005-10-20 | 2008-10-09 | The Ohio State University Research Foundation | Drug and Gene Delivery by Polymer Nanonozzle and Nanotip Cell Patch |
| JP4713671B1 (ja) * | 2010-01-22 | 2011-06-29 | ネッパジーン株式会社 | エレクトロポレーション法による外来遺伝子導入法 |
| JP5585204B2 (ja) * | 2010-05-18 | 2014-09-10 | 大日本印刷株式会社 | マイクロチップ及びその製造方法 |
| US9816086B2 (en) * | 2010-07-06 | 2017-11-14 | The Ohio State University | Dose and location controlled drug/gene/particle delivery to individual cells by nanoelectroporation |
| CN101928666B (zh) * | 2010-07-30 | 2013-04-03 | 北京大学 | 一种流式电穿孔装置及系统 |
| PT2768942T (pt) * | 2011-10-17 | 2020-01-21 | Massachusetts Inst Technology | Entrega intracelular |
-
2015
- 2015-12-14 KR KR1020150178130A patent/KR102428463B1/ko active Active
- 2015-12-14 KR KR1020150178234A patent/KR20160079661A/ko not_active Ceased
- 2015-12-14 KR KR1020150178183A patent/KR102428464B1/ko active Active
- 2015-12-23 DK DK15202528.4T patent/DK3037518T3/da active
- 2015-12-23 ES ES15202528T patent/ES2808828T3/es active Active
- 2015-12-24 JP JP2017535710A patent/JP6883517B2/ja active Active
- 2015-12-24 JP JP2017535711A patent/JP6805152B2/ja active Active
- 2015-12-24 JP JP2017535708A patent/JP2018504110A/ja active Pending
- 2015-12-28 US US14/980,713 patent/US20160272961A1/en not_active Abandoned
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