JP2018171062A5 - - Google Patents
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- JP2018171062A5 JP2018171062A5 JP2018109490A JP2018109490A JP2018171062A5 JP 2018171062 A5 JP2018171062 A5 JP 2018171062A5 JP 2018109490 A JP2018109490 A JP 2018109490A JP 2018109490 A JP2018109490 A JP 2018109490A JP 2018171062 A5 JP2018171062 A5 JP 2018171062A5
- Authority
- JP
- Japan
- Prior art keywords
- cell population
- test
- cancer cells
- domain peptide
- contacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261702967P | 2012-09-19 | 2012-09-19 | |
| US61/702,967 | 2012-09-19 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015533194A Division JP6352924B2 (ja) | 2012-09-19 | 2013-09-19 | ダイナミックｂｈ３プロファイリング |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018171062A JP2018171062A (ja) | 2018-11-08 |
| JP2018171062A5 true JP2018171062A5 (enExample) | 2018-12-20 |
| JP6684857B2 JP6684857B2 (ja) | 2020-04-22 |
Family
ID=49304346
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015533194A Active JP6352924B2 (ja) | 2012-09-19 | 2013-09-19 | ダイナミックｂｈ３プロファイリング |
| JP2018109490A Active JP6684857B2 (ja) | 2012-09-19 | 2018-06-07 | ダイナミックｂｈ３プロファイリング |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015533194A Active JP6352924B2 (ja) | 2012-09-19 | 2013-09-19 | ダイナミックｂｈ３プロファイリング |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10393733B2 (enExample) |
| EP (1) | EP2898327A1 (enExample) |
| JP (2) | JP6352924B2 (enExample) |
| AU (1) | AU2013317985B2 (enExample) |
| CA (1) | CA2885230C (enExample) |
| HK (1) | HK1213046A1 (enExample) |
| WO (1) | WO2014047342A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004022580A2 (en) | 2002-09-09 | 2004-03-18 | Dana-Farber Cancer Institute, Inc. | Bh3 peptides and method of use thereof |
| US8221966B2 (en) | 2006-03-31 | 2012-07-17 | Dana Farber Cancer Institute | Methods of determining cellular chemosensitivity |
| WO2014047342A1 (en) | 2012-09-19 | 2014-03-27 | Dana-Farber Cancer Institute, Inc. | Dynamic bh3 profiling |
| JP2016526892A (ja) * | 2013-07-18 | 2016-09-08 | ユートロピクス ファーマシューティカルズ， インコーポレイテッド | 示差的ｂｈ３ミトコンドリアプロファイリング |
| JP6663852B2 (ja) * | 2013-09-19 | 2020-03-13 | デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド | Ｂｈ３プロファイリングの方法 |
| HK1247250A1 (zh) | 2015-01-12 | 2018-09-21 | Eutropics Pharmaceuticals, Inc. | 用於指导癌症治疗的内容相关的诊断测试 |
| US20180100859A1 (en) * | 2015-03-24 | 2018-04-12 | Eutropics Pharmaceuticals, Inc. | Surrogate functional biomarker for solid tumor cancer |
| JP6851978B2 (ja) | 2015-04-20 | 2021-03-31 | スミトモ ダイニッポン ファーマ オンコロジー， インコーポレイテッド | ミトコンドリアプロファイリングによるアルボシジブ応答の予測 |
| EP3289094B1 (en) * | 2015-04-27 | 2024-06-05 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for assessing toxicity using dynamic bh3 profiling |
| JP6510075B2 (ja) | 2015-05-18 | 2019-05-08 | トレロ ファーマシューティカルズ， インコーポレイテッド | バイオアベイラビリティが高いアルボシジブプロドラッグ |
| EP3331510A4 (en) | 2015-08-03 | 2019-04-03 | Tolero Pharmaceuticals, Inc. | COMBINATION THERAPIES FOR THE TREATMENT OF CANCER |
| US11279694B2 (en) | 2016-11-18 | 2022-03-22 | Sumitomo Dainippon Pharma Oncology, Inc. | Alvocidib prodrugs and their use as protein kinase inhibitors |
| CA3047557A1 (en) | 2016-12-19 | 2018-06-28 | Tolero Pharmaceuticals, Inc. | Profiling peptides and methods for sensitivity profiling |
| WO2018134254A1 (en) | 2017-01-17 | 2018-07-26 | Heparegenix Gmbh | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death |
| EP3385715A1 (en) | 2017-04-04 | 2018-10-10 | Medizinische Hochschule Hannover | Analytical process for predicting the therapeutic effect of bh3 mimetics |
| WO2019055579A1 (en) | 2017-09-12 | 2019-03-21 | Tolero Pharmaceuticals, Inc. | TREATMENT REGIME FOR CANCERS THAT ARE INSENSITIVE TO BCL-2 INHIBITORS USING THE MCL-1 ALVOCIDIB INHIBITOR |
| US11034710B2 (en) | 2018-12-04 | 2021-06-15 | Sumitomo Dainippon Pharma Oncology, Inc. | CDK9 inhibitors and polymorphs thereof for use as agents for treatment of cancer |
| WO2020176689A1 (en) * | 2019-02-26 | 2020-09-03 | Dana-Farber Cancer Institute, Inc. | Live cell imaging dynamic bh3 profiling |
| US11793802B2 (en) | 2019-03-20 | 2023-10-24 | Sumitomo Pharma Oncology, Inc. | Treatment of acute myeloid leukemia (AML) with venetoclax failure |
| EP4306953A1 (en) | 2022-07-12 | 2024-01-17 | Fundació Institut de Bioenginyeria de Catalunya (IBEC) | Real-time tracking of apoptosis |
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| JP2016526892A (ja) | 2013-07-18 | 2016-09-08 | ユートロピクス ファーマシューティカルズ， インコーポレイテッド | 示差的ｂｈ３ミトコンドリアプロファイリング |
| JP6663852B2 (ja) | 2013-09-19 | 2020-03-13 | デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド | Ｂｈ３プロファイリングの方法 |
| EP3289094B1 (en) | 2015-04-27 | 2024-06-05 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for assessing toxicity using dynamic bh3 profiling |
| WO2017007858A1 (en) | 2015-07-06 | 2017-01-12 | Whitehead Institute For Biomedical Research | Methods and compositions relating to proteasome inhibitor resistance |
| WO2020176689A1 (en) | 2019-02-26 | 2020-09-03 | Dana-Farber Cancer Institute, Inc. | Live cell imaging dynamic bh3 profiling |
-
2013
- 2013-09-19 WO PCT/US2013/060707 patent/WO2014047342A1/en not_active Ceased
- 2013-09-19 US US14/429,272 patent/US10393733B2/en active Active
- 2013-09-19 JP JP2015533194A patent/JP6352924B2/ja active Active
- 2013-09-19 CA CA2885230A patent/CA2885230C/en active Active
- 2013-09-19 EP EP13773484.4A patent/EP2898327A1/en active Pending
- 2013-09-19 HK HK16100721.8A patent/HK1213046A1/zh unknown
- 2013-09-19 AU AU2013317985A patent/AU2013317985B2/en active Active
-
2018
- 2018-06-07 JP JP2018109490A patent/JP6684857B2/ja active Active
-
2019
- 2019-07-11 US US16/508,459 patent/US11815508B2/en active Active
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