JP2018150298A5 - - Google Patents
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- Publication number
- JP2018150298A5 JP2018150298A5 JP2018044050A JP2018044050A JP2018150298A5 JP 2018150298 A5 JP2018150298 A5 JP 2018150298A5 JP 2018044050 A JP2018044050 A JP 2018044050A JP 2018044050 A JP2018044050 A JP 2018044050A JP 2018150298 A5 JP2018150298 A5 JP 2018150298A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 1
Claims (1)
- 式：
６、
２２、
２８、
ＩＶ、
１１、
１３、
１５、
１６、
２６、
２７、
３０、
３１、
３２、
３４、
３６、
３７、
４３、または
４４
を有する化合物。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361779619P | 2013-03-13 | 2013-03-13 | |
| US61/779,619 | 2013-03-13 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562108A Division JP6363120B2 (ja) | 2013-03-13 | 2014-03-12 | ベンゾオキサゼピン化合物の作製方法 |
Related Child Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018153231A Division JP6663459B2 (ja) | 2013-03-13 | 2018-08-16 | ベンゾオキサゼピン化合物の作製方法 |
| JP2018219226A Division JP2019089762A (ja) | 2013-03-13 | 2018-11-22 | ベンゾオキサゼピン化合物の作製方法 |
| JP2020032846A Division JP2020114814A (ja) | 2013-03-13 | 2020-02-28 | ベンゾオキサゼピン化合物の作製方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018150298A JP2018150298A (ja) | 2018-09-27 |
| JP2018150298A5 true JP2018150298A5 (ja) | 2019-01-31 |
Family
ID=50241450
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562108A Active JP6363120B2 (ja) | 2013-03-13 | 2014-03-12 | ベンゾオキサゼピン化合物の作製方法 |
| JP2017135083A Active JP6442005B2 (ja) | 2013-03-13 | 2017-07-10 | ベンゾオキサゼピン化合物の作製方法 |
| JP2018044050A Pending JP2018150298A (ja) | 2013-03-13 | 2018-03-12 | ベンゾオキサゼピン化合物の作製方法 |
| JP2018153231A Active JP6663459B2 (ja) | 2013-03-13 | 2018-08-16 | ベンゾオキサゼピン化合物の作製方法 |
| JP2018219226A Pending JP2019089762A (ja) | 2013-03-13 | 2018-11-22 | ベンゾオキサゼピン化合物の作製方法 |
| JP2020032846A Pending JP2020114814A (ja) | 2013-03-13 | 2020-02-28 | ベンゾオキサゼピン化合物の作製方法 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562108A Active JP6363120B2 (ja) | 2013-03-13 | 2014-03-12 | ベンゾオキサゼピン化合物の作製方法 |
| JP2017135083A Active JP6442005B2 (ja) | 2013-03-13 | 2017-07-10 | ベンゾオキサゼピン化合物の作製方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018153231A Active JP6663459B2 (ja) | 2013-03-13 | 2018-08-16 | ベンゾオキサゼピン化合物の作製方法 |
| JP2018219226A Pending JP2019089762A (ja) | 2013-03-13 | 2018-11-22 | ベンゾオキサゼピン化合物の作製方法 |
| JP2020032846A Pending JP2020114814A (ja) | 2013-03-13 | 2020-02-28 | ベンゾオキサゼピン化合物の作製方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9303043B2 (ja) |
| EP (3) | EP3404032A3 (ja) |
| JP (6) | JP6363120B2 (ja) |
| KR (3) | KR101821468B1 (ja) |
| CN (2) | CN108929333A (ja) |
| AR (1) | AR095365A1 (ja) |
| AU (3) | AU2014230812B2 (ja) |
| BR (1) | BR112015020716A2 (ja) |
| CA (6) | CA2897618A1 (ja) |
| HK (1) | HK1215433A1 (ja) |
| IL (1) | IL240793A0 (ja) |
| MX (1) | MX2015011438A (ja) |
| NZ (1) | NZ711192A (ja) |
| RU (2) | RU2018109979A (ja) |
| SG (2) | SG10201706760YA (ja) |
| WO (1) | WO2014140073A1 (ja) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109293674A (zh) | 2013-12-16 | 2019-02-01 | 豪夫迈·罗氏有限公司 | Gdc-0032的多晶型物、其制备方法和药物用途 |
| NZ736222A (en) * | 2015-07-02 | 2024-05-31 | F Hoffmann La Roche Ag | Benzoxazepin oxazolidinone compounds and methods of use |
| WO2017001658A1 (en) | 2015-07-02 | 2017-01-05 | F. Hoffmann-La Roche Ag | Benzoxazepin oxazolidinone compounds and methods of use |
| CN105906635A (zh) * | 2016-06-08 | 2016-08-31 | 上海大学 | 全氟烷基苯并氮杂*并喹喔啉衍生物及其合成方法 |
| WO2018021508A1 (ja) | 2016-07-29 | 2018-02-01 | 日本たばこ産業株式会社 | ピラゾール－アミド化合物の製造方法 |
| TW201825465A (zh) | 2016-09-23 | 2018-07-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| TW201813963A (zh) | 2016-09-23 | 2018-04-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| TW201815787A (zh) | 2016-09-23 | 2018-05-01 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| MX2019006958A (es) | 2016-12-15 | 2019-08-01 | Hoffmann La Roche | Proceso para la preparacion de (s)-2-((2-((s)-4-(difluorometil)-2- oxooxazolidin-3-il)-5,6-dihidrobenzo[f]imidazo[1,2-d] [1,4]oxazepin-9-il)amino)propanamida. |
| CN108752237A (zh) * | 2018-07-05 | 2018-11-06 | 四川青木制药有限公司 | 一种对氨基苯甲脒盐酸盐的新制备方法 |
| WO2020130125A1 (ja) | 2018-12-21 | 2020-06-25 | 第一三共株式会社 | 抗体－薬物コンジュゲートとキナーゼ阻害剤の組み合わせ |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5846824A (en) | 1994-02-07 | 1998-12-08 | Ludwig Institute For Cancer Research | Polypeptides having kinase activity, their preparation and use |
| GB9208135D0 (en) | 1992-04-13 | 1992-05-27 | Ludwig Inst Cancer Res | Polypeptides having kinase activity,their preparation and use |
| US6274327B1 (en) | 1992-04-13 | 2001-08-14 | Ludwig Institute For Cancer Research | Polypeptides having kinase activity, their preparation and use |
| AU1228100A (en) * | 1998-10-23 | 2000-05-15 | Dow Agrosciences Llc | 3-(substituted phenyl)-5-(substituted cyclopropyl)-1,2,4-triazole compounds |
| KR20040024564A (ko) | 2001-07-12 | 2004-03-20 | 아베시아 리미티드 | 마이크로캡슐화된 촉매, 이의 제조 방법 및 이의 사용 방법 |
| MXPA04002931A (es) * | 2001-10-12 | 2005-04-11 | Bayer Pharmaceuticals Corp | Heterociclos que contienen nitrogeno de 5 miembros sustituidos con fenilo para el tratamiento de la obesidad. |
| WO2007056170A2 (en) | 2005-11-02 | 2007-05-18 | Bayer Healthcare Ag | Pyrrolo[2,1-f] [1,2,4] triazin-4-ylamines igf-1r kinase inhibitors for the treatment of cancer and other hyperproliferative diseases |
| ES2393132T3 (es) | 2006-10-23 | 2012-12-18 | Sgx Pharmaceuticals, Inc. | Moduoladores de proteína quinasa de triazolopiridazina |
| EP2084162B1 (en) * | 2006-10-23 | 2012-09-12 | SGX Pharmaceuticals, Inc. | Bicyclic triazoles as protein kinase modulators |
| JP2010516680A (ja) * | 2007-01-19 | 2010-05-20 | エックスカバリー，インコーポレイテッド | キナーゼ阻害薬化合物 |
| ES2439705T3 (es) * | 2007-10-25 | 2014-01-24 | Genentech, Inc. | Proceso para la preparación de compuestos de tienopirimidina |
| CN102015693B (zh) * | 2008-02-21 | 2014-10-29 | 默沙东公司 | 作为erk抑制剂的化合物 |
| ES2480994T3 (es) | 2008-03-31 | 2014-07-29 | Genentech, Inc. | Compuestos de tipo benzopirano y benzoxepina inhibidores de PI3K y métodos de uso |
| GB0810902D0 (en) | 2008-06-13 | 2008-07-23 | Astex Therapeutics Ltd | New compounds |
| WO2011036280A1 (en) * | 2009-09-28 | 2011-03-31 | F. Hoffmann-La Roche Ag | Benzoxazepin pi3k inhibitor compounds and methods of use |
| UA108863C2 (ru) | 2009-09-28 | 2015-06-25 | Ф. Хоффманн-Ля Рош Аг | Бензоксепиновые ингибиторы pi3 и их применение |
| AU2010313469A1 (en) * | 2009-10-29 | 2012-06-07 | Merck Sharp & Dohme Corp. | Bridged Bicyclic Piperidine Derivatives and methods of use thereof |
| CN102558167A (zh) * | 2010-12-29 | 2012-07-11 | 中国医学科学院药物研究所 | Gk和ppar双重激动活性的噻唑烷二酮衍生物 |
| MX340013B (es) | 2011-03-21 | 2016-06-22 | Hoffmann La Roche | Compuestos de benzoxazepina selectivos para fosfatidilinositol 3-cinasa (pi3k) p110 delta y metodos de uso. |
| NO3175985T3 (ja) * | 2011-07-01 | 2018-04-28 | ||
| CN104379163A (zh) | 2012-06-08 | 2015-02-25 | 霍夫曼-拉罗奇有限公司 | 用于治疗癌症的磷酸肌醇3激酶抑制剂化合物和化疗剂的突变选择性及组合 |
-
2014
- 2014-03-12 WO PCT/EP2014/054786 patent/WO2014140073A1/en active Application Filing
- 2014-03-12 AU AU2014230812A patent/AU2014230812B2/en not_active Ceased
- 2014-03-12 EP EP18173513.5A patent/EP3404032A3/en active Pending
- 2014-03-12 CA CA2897618A patent/CA2897618A1/en not_active Abandoned
- 2014-03-12 SG SG10201706760YA patent/SG10201706760YA/en unknown
- 2014-03-12 RU RU2018109979A patent/RU2018109979A/ru not_active Application Discontinuation
- 2014-03-12 CA CA3005118A patent/CA3005118A1/en not_active Abandoned
- 2014-03-12 KR KR1020157024484A patent/KR101821468B1/ko active IP Right Grant
- 2014-03-12 RU RU2015138488A patent/RU2649976C2/ru not_active IP Right Cessation
- 2014-03-12 CA CA2948763A patent/CA2948763C/en not_active Expired - Fee Related
- 2014-03-12 BR BR112015020716A patent/BR112015020716A2/pt not_active Application Discontinuation
- 2014-03-12 CA CA2948765A patent/CA2948765A1/en not_active Abandoned
- 2014-03-12 CA CA3005112A patent/CA3005112A1/en not_active Abandoned
- 2014-03-12 EP EP20204345.1A patent/EP3845540A1/en active Pending
- 2014-03-12 US US14/205,634 patent/US9303043B2/en active Active
- 2014-03-12 CN CN201810489045.8A patent/CN108929333A/zh active Pending
- 2014-03-12 SG SG11201507394RA patent/SG11201507394RA/en unknown
- 2014-03-12 CA CA3005103A patent/CA3005103A1/en not_active Abandoned
- 2014-03-12 NZ NZ711192A patent/NZ711192A/en not_active IP Right Cessation
- 2014-03-12 KR KR1020177016062A patent/KR101871133B1/ko active IP Right Grant
- 2014-03-12 CN CN201480015055.8A patent/CN105377856B/zh active Active
- 2014-03-12 AR ARP140100904A patent/AR095365A1/es unknown
- 2014-03-12 MX MX2015011438A patent/MX2015011438A/es unknown
- 2014-03-12 KR KR1020187016976A patent/KR20180070715A/ko not_active Application Discontinuation
- 2014-03-12 EP EP14709314.0A patent/EP2970329A1/en not_active Withdrawn
- 2014-03-12 JP JP2015562108A patent/JP6363120B2/ja active Active
-
2015
- 2015-08-24 IL IL240793A patent/IL240793A0/en unknown
-
2016
- 2016-03-23 HK HK16103386.8A patent/HK1215433A1/zh unknown
- 2016-06-28 AU AU2016204432A patent/AU2016204432B2/en not_active Ceased
-
2017
- 2017-07-10 JP JP2017135083A patent/JP6442005B2/ja active Active
-
2018
- 2018-02-27 AU AU2018201393A patent/AU2018201393A1/en not_active Abandoned
- 2018-03-12 JP JP2018044050A patent/JP2018150298A/ja active Pending
- 2018-08-16 JP JP2018153231A patent/JP6663459B2/ja active Active
- 2018-11-22 JP JP2018219226A patent/JP2019089762A/ja active Pending
-
2020
- 2020-02-28 JP JP2020032846A patent/JP2020114814A/ja active Pending