JP2018168171A5 - - Google Patents
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- Publication number
- JP2018168171A5 JP2018168171A5 JP2018117808A JP2018117808A JP2018168171A5 JP 2018168171 A5 JP2018168171 A5 JP 2018168171A5 JP 2018117808 A JP2018117808 A JP 2018117808A JP 2018117808 A JP2018117808 A JP 2018117808A JP 2018168171 A5 JP2018168171 A5 JP 2018168171A5
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- JP
- Japan
- Prior art keywords
- compound
- following structure
- following
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 4
Claims (4)
- 以下の構造：
を有する化合物。 - 以下の構造：
を有する化合物。 - 以下の構造：
を有する化合物。 - 以下の構造：
を有する化合物。
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361801641P | 2013-03-15 | 2013-03-15 | |
| US61/801,641 | 2013-03-15 | ||
| EP13306056 | 2013-07-23 | ||
| EP13306056.6 | 2013-07-23 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562366A Division JP6438417B2 (ja) | 2013-03-15 | 2014-03-14 | スフィンゴミエリンおよびジヒドロスフィンゴミエリンの合成のための方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018168171A JP2018168171A (ja) | 2018-11-01 |
| JP2018168171A5 true JP2018168171A5 (ja) | 2019-01-17 |
Family
ID=51538203
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562366A Active JP6438417B2 (ja) | 2013-03-15 | 2014-03-14 | スフィンゴミエリンおよびジヒドロスフィンゴミエリンの合成のための方法 |
| JP2018117808A Pending JP2018168171A (ja) | 2013-03-15 | 2018-06-21 | スフィンゴミエリンおよびジヒドロスフィンゴミエリンの合成のための方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562366A Active JP6438417B2 (ja) | 2013-03-15 | 2014-03-14 | スフィンゴミエリンおよびジヒドロスフィンゴミエリンの合成のための方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US20140316154A1 (ja) |
| EP (3) | EP3842443A1 (ja) |
| JP (2) | JP6438417B2 (ja) |
| KR (1) | KR20150132188A (ja) |
| CN (1) | CN105051051B (ja) |
| AU (2) | AU2014229638B2 (ja) |
| BR (1) | BR112015023558A2 (ja) |
| CA (1) | CA2900902C (ja) |
| DK (1) | DK3363805T3 (ja) |
| HK (2) | HK1212705A1 (ja) |
| MX (1) | MX2015012877A (ja) |
| PH (1) | PH12015501835A1 (ja) |
| SG (2) | SG10201804887YA (ja) |
| WO (1) | WO2014140787A2 (ja) |
| ZA (1) | ZA201505860B (ja) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2396017T1 (sl) | 2009-02-16 | 2015-12-31 | Cerenis Therapeutics Holding Sa | Mimika apolipoproteina A-1 |
| SG10201708237SA (en) | 2010-10-18 | 2017-11-29 | Cerenis Therapeutics Holding Sa | Compounds, compositions and methods useful for cholesterol mobilisation |
| US9708354B2 (en) | 2013-03-15 | 2017-07-18 | Cerenis Therapeutics Holding Sa | Methods for the synthesis of sphingomyelins and dihydrosphingomyelins |
| EP3842443A1 (en) * | 2013-03-15 | 2021-06-30 | Cerenis Therapeutics Holding SA | Methods for the synthesis of sphingomyelins and dihydrosphingomyelins |
| US20190048049A1 (en) | 2017-08-10 | 2019-02-14 | Cerenis Therapeutics Holding Sa | Cargomers |
| WO2019030575A1 (en) | 2017-08-10 | 2019-02-14 | Cerenis Therapeutics Holding | APOMÈRES |
| CN111757886A (zh) * | 2018-03-27 | 2020-10-09 | 日油株式会社 | 鞘磷脂衍生的脂质及其生产方法 |
| JP7303618B2 (ja) * | 2018-10-05 | 2023-07-05 | 日本精化株式会社 | スフィンゴリン脂質前駆体及びその製造方法、並びに、スフィンゴリン脂質の製造方法 |
| KR20230004606A (ko) | 2020-04-16 | 2023-01-06 | 아비오닉스 파마 에스에이 | 신장 질환을 치료하기 위한 cer-001 요법 |
| WO2021209808A1 (en) | 2020-04-16 | 2021-10-21 | Abionyx Pharma Sa | Cer-001 therapy for treating kidney disease |
| AU2021256086A1 (en) | 2020-04-16 | 2022-12-15 | Abionyx Pharma Sa | Methods for treating acute conditions using lipid binding protein- based complexes |
| WO2022069942A2 (en) | 2020-10-01 | 2022-04-07 | Abionyx Pharma Sa | Methods for treating eye diseases using lipid binding protein-based complexes |
| MX2023012223A (es) | 2021-04-15 | 2023-10-26 | Abionyx Pharma Sa | Uso de complejos a base de proteinas de union a lipidos en soluciones de conservacion de organos. |
| WO2023194797A1 (en) | 2022-04-06 | 2023-10-12 | Abionyx Pharma Sa | Methods for treating eye diseases using lipid binding protein-based complexes |
| WO2023194798A1 (en) | 2022-04-06 | 2023-10-12 | Abionyx Pharma Sa | Methods for treating leukocytosis, endothelial dysfunction and carditis using lipid binding protein-based complexes |
| WO2023237927A2 (en) | 2022-06-10 | 2023-12-14 | Abionyx Pharma Sa | Methods for treating hyperinflammatory conditions using lipid binding protein -based complexes |
| WO2023237935A2 (en) | 2022-06-10 | 2023-12-14 | Abionyx Pharma Sa | Methods for treating acute conditions using lipid binding protein-based complexes |
| WO2024003612A2 (en) | 2022-06-28 | 2024-01-04 | Abionyx Pharma Sa | Compounds and processes for the synthesis of sphingomyelins |
| WO2024150064A1 (en) | 2023-01-13 | 2024-07-18 | Abionyx Pharma Sa | Lipid binding protein molecule therapy |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0146810A3 (de) | 1983-12-05 | 1987-05-13 | Solco Basel AG | Verfahren zur Herstellung von Sphingosinderivaten |
| US5220043A (en) * | 1991-03-21 | 1993-06-15 | Ohio University | Synthesis of D-erythro-sphingomyelins |
| US5766627A (en) | 1993-11-16 | 1998-06-16 | Depotech | Multivescular liposomes with controlled release of encapsulated biologically active substances |
| JP3002702B2 (ja) | 1993-11-16 | 2000-01-24 | スカイファーム インコーポレーテッド | 活性物質の制御放出を有する小胞 |
| WO1999041266A1 (en) | 1998-02-12 | 1999-08-19 | Emory University | Sphingolipid derivatives and their methods of use |
| JP2004002215A (ja) * | 2002-05-23 | 2004-01-08 | National Institute Of Advanced Industrial & Technology | スフィンゴ脂質誘導体の製造方法 |
| JP2007517860A (ja) | 2004-01-15 | 2007-07-05 | バイオラブ・リミテッド | スフィンゴミエリン、その中間体及びその調製方法 |
| EP1750673B1 (en) | 2004-05-17 | 2009-12-02 | Tekmira Pharmaceuticals Corporation | Liposomal formulations comprising dihydrosphingomyelin and methods of use thereof |
| ATE417607T1 (de) * | 2004-06-29 | 2009-01-15 | Jado Technologies Gmbh | Sphingolipide gegen krankhafte prozesse in lipid rafts |
| JP4825947B2 (ja) | 2004-08-04 | 2011-11-30 | 学校法人関西学院 | 不飽和アミノジオール類の製造方法 |
| JP2006045113A (ja) | 2004-08-04 | 2006-02-16 | Kemikurea:Kk | リン酸エステル類 |
| US8206750B2 (en) | 2005-03-24 | 2012-06-26 | Cerenis Therapeutics Holding S.A. | Charged lipoprotein complexes and their uses |
| US7470664B2 (en) * | 2005-07-20 | 2008-12-30 | Merck & Co., Inc. | HCV NS3 protease inhibitors |
| JP2007204384A (ja) | 2006-01-31 | 2007-08-16 | Kemikurea:Kk | 光学活性リン酸誘導体およびこれを用いた光学活性スフィンゴシン１−リン酸誘導体の製造方法 |
| JP5429734B2 (ja) * | 2007-02-09 | 2014-02-26 | 国立大学法人岐阜大学 | スフィンゴ糖脂質の合成法 |
| US8093395B2 (en) | 2007-03-09 | 2012-01-10 | Otsuka Chemical Co., Ltd. | Sphingosine compound, method for producing the same, and sphingomyelinase inhibitor |
| US20110250266A1 (en) | 2008-10-07 | 2011-10-13 | Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. | Liposomal systems comprising sphingomyelin |
| RU2017126088A (ru) | 2011-02-07 | 2019-01-31 | Серени Терапеутикс Холдинг С.А. | Липопротеиновые комплексы и их получение и применения |
| FR3000959B1 (fr) * | 2013-01-14 | 2015-08-21 | Holis Technologies | Nouveaux intermediaires de synthese permettant d'acceder avec de bons rendements a des derives de sphingosines, ceramides et sphingomyelines |
| US9708354B2 (en) | 2013-03-15 | 2017-07-18 | Cerenis Therapeutics Holding Sa | Methods for the synthesis of sphingomyelins and dihydrosphingomyelins |
| EP3842443A1 (en) | 2013-03-15 | 2021-06-30 | Cerenis Therapeutics Holding SA | Methods for the synthesis of sphingomyelins and dihydrosphingomyelins |
-
2014
- 2014-03-14 EP EP20214357.4A patent/EP3842443A1/en active Pending
- 2014-03-14 CA CA2900902A patent/CA2900902C/en active Active
- 2014-03-14 SG SG10201804887YA patent/SG10201804887YA/en unknown
- 2014-03-14 MX MX2015012877A patent/MX2015012877A/es unknown
- 2014-03-14 EP EP18160532.0A patent/EP3363805B1/en active Active
- 2014-03-14 AU AU2014229638A patent/AU2014229638B2/en active Active
- 2014-03-14 US US14/213,269 patent/US20140316154A1/en not_active Abandoned
- 2014-03-14 CN CN201480015700.6A patent/CN105051051B/zh active Active
- 2014-03-14 KR KR1020157025911A patent/KR20150132188A/ko not_active Application Discontinuation
- 2014-03-14 EP EP14729036.5A patent/EP2970344A2/en not_active Withdrawn
- 2014-03-14 SG SG11201506456VA patent/SG11201506456VA/en unknown
- 2014-03-14 WO PCT/IB2014/000494 patent/WO2014140787A2/en active Application Filing
- 2014-03-14 DK DK18160532.0T patent/DK3363805T3/da active
- 2014-03-14 JP JP2015562366A patent/JP6438417B2/ja active Active
- 2014-03-14 BR BR112015023558A patent/BR112015023558A2/pt not_active Application Discontinuation
-
2015
- 2015-04-22 US US14/693,520 patent/US9643915B2/en active Active
- 2015-08-14 ZA ZA2015/05860A patent/ZA201505860B/en unknown
- 2015-08-19 PH PH12015501835A patent/PH12015501835A1/en unknown
-
2016
- 2016-01-19 HK HK16100549.8A patent/HK1212705A1/zh unknown
- 2016-02-24 HK HK16102047.1A patent/HK1214266A1/zh unknown
-
2017
- 2017-04-04 US US15/478,532 patent/US20170204122A1/en not_active Abandoned
-
2018
- 2018-06-21 JP JP2018117808A patent/JP2018168171A/ja active Pending
- 2018-11-21 AU AU2018267598A patent/AU2018267598A1/en not_active Abandoned