JP2018096916A5 - - Google Patents
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- JP2018096916A5 JP2018096916A5 JP2016243860A JP2016243860A JP2018096916A5 JP 2018096916 A5 JP2018096916 A5 JP 2018096916A5 JP 2016243860 A JP2016243860 A JP 2016243860A JP 2016243860 A JP2016243860 A JP 2016243860A JP 2018096916 A5 JP2018096916 A5 JP 2018096916A5
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- JP
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- Prior art keywords
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- pretreatment
- Prior art date
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- 239000003153 chemical reaction reagent Substances 0.000 claims description 144
- 238000006243 chemical reaction Methods 0.000 claims description 76
- 238000003860 storage Methods 0.000 claims description 35
- 238000007781 pre-processing Methods 0.000 claims description 34
- 238000004458 analytical method Methods 0.000 claims description 30
- 238000000034 method Methods 0.000 claims description 30
- 238000005119 centrifugation Methods 0.000 claims description 14
- 238000009434 installation Methods 0.000 claims description 14
- 239000006228 supernatant Substances 0.000 claims description 14
- 210000004027 cell Anatomy 0.000 claims description 13
- 238000000926 separation method Methods 0.000 claims description 7
- 238000002203 pretreatment Methods 0.000 claims description 6
- 238000010186 staining Methods 0.000 claims description 5
- 238000007901 in situ hybridization Methods 0.000 claims description 3
- 101710160107 Outer membrane protein A Proteins 0.000 claims description 2
- 239000012528 membrane Substances 0.000 claims description 2
- 239000012128 staining reagent Substances 0.000 claims 3
- 239000013076 target substance Substances 0.000 claims 1
- 238000013019 agitation Methods 0.000 description 11
- 238000001816 cooling Methods 0.000 description 10
- 239000000872 buffer Substances 0.000 description 8
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 8
- 239000003219 hemolytic agent Substances 0.000 description 8
- 239000007788 liquid Substances 0.000 description 8
- 239000002953 phosphate buffered saline Substances 0.000 description 8
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 6
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
- 239000000427 antigen Substances 0.000 description 6
- 102000036639 antigens Human genes 0.000 description 6
- 108091007433 antigens Proteins 0.000 description 6
- 238000009396 hybridization Methods 0.000 description 6
- 210000000265 leukocyte Anatomy 0.000 description 6
- 238000000684 flow cytometry Methods 0.000 description 5
- 238000004140 cleaning Methods 0.000 description 4
- 238000010792 warming Methods 0.000 description 4
- 210000004970 cd4 cell Anatomy 0.000 description 3
- 239000011535 reaction buffer Substances 0.000 description 3
- 206010018910 Haemolysis Diseases 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 230000008588 hemolysis Effects 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 239000001509 sodium citrate Substances 0.000 description 2
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 239000006180 TBST buffer Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000009089 cytolysis Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000010212 intracellular staining Methods 0.000 description 1
- 238000003260 vortexing Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016243860A JP6937116B2 (ja) | 2016-12-15 | 2016-12-15 | 前処理装置及び前処理方法 |
| CN202210846699.8A CN115267234A (zh) | 2016-12-15 | 2017-12-07 | 前处理装置及前处理方法 |
| CN201711283284.XA CN108226551B (zh) | 2016-12-15 | 2017-12-07 | 前处理装置及前处理方法 |
| EP17206975.9A EP3336517A1 (en) | 2016-12-15 | 2017-12-13 | Temperature adjustable centrifugal separation |
| US15/842,470 US11099200B2 (en) | 2016-12-15 | 2017-12-14 | Pretreatment apparatus and pretreatment method |
| US17/373,495 US20210333299A1 (en) | 2016-12-15 | 2021-07-12 | Pretreatment apparatus and pretreatment method |
| JP2021139222A JP7223085B2 (ja) | 2016-12-15 | 2021-08-27 | 前処理装置及び前処理方法 |
| JP2023015226A JP7503160B2 (ja) | 2016-12-15 | 2023-02-03 | 前処理装置及び前処理方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016243860A JP6937116B2 (ja) | 2016-12-15 | 2016-12-15 | 前処理装置及び前処理方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021139222A Division JP7223085B2 (ja) | 2016-12-15 | 2021-08-27 | 前処理装置及び前処理方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018096916A JP2018096916A (ja) | 2018-06-21 |
| JP2018096916A5 true JP2018096916A5 (enExample) | 2019-02-14 |
| JP6937116B2 JP6937116B2 (ja) | 2021-09-22 |
Family
ID=60888155
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016243860A Active JP6937116B2 (ja) | 2016-12-15 | 2016-12-15 | 前処理装置及び前処理方法 |
| JP2021139222A Active JP7223085B2 (ja) | 2016-12-15 | 2021-08-27 | 前処理装置及び前処理方法 |
| JP2023015226A Active JP7503160B2 (ja) | 2016-12-15 | 2023-02-03 | 前処理装置及び前処理方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021139222A Active JP7223085B2 (ja) | 2016-12-15 | 2021-08-27 | 前処理装置及び前処理方法 |
| JP2023015226A Active JP7503160B2 (ja) | 2016-12-15 | 2023-02-03 | 前処理装置及び前処理方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US11099200B2 (enExample) |
| EP (1) | EP3336517A1 (enExample) |
| JP (3) | JP6937116B2 (enExample) |
| CN (2) | CN115267234A (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020017409A1 (ja) * | 2018-07-17 | 2020-01-23 | 国立大学法人神戸大学 | 攪拌装置及び前処理装置 |
| CN109238811B (zh) * | 2018-09-27 | 2024-05-10 | 武汉纺织大学 | 一种全自动组织细胞染色系统 |
| US20220353957A1 (en) * | 2018-09-28 | 2022-11-03 | Siemens Healthcare Diagnostics Inc. | Positive temperature coefficient heating of laboratory diagnostic instruments |
| CN111141564A (zh) * | 2018-11-02 | 2020-05-12 | 莱卡生物系统努斯洛赫有限责任公司 | 用于提示溶剂的状态的装置、方法和组织处理机 |
| EP4045181A1 (en) * | 2019-11-04 | 2022-08-24 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Synthesizer for oligo- and polysaccharides on solid phase |
| JP7515281B2 (ja) * | 2020-03-30 | 2024-07-12 | シスメックス株式会社 | 遠心分離機および試料調製装置 |
| JP7455235B2 (ja) * | 2020-12-17 | 2024-03-25 | 株式会社日立ハイテク | 自動分析装置 |
| CN112799444A (zh) * | 2020-12-27 | 2021-05-14 | 北京工业大学 | 一种基于51单片机的血液寄生虫检测温控加热仪 |
| CN115901396A (zh) * | 2022-12-24 | 2023-04-04 | 西安交通大学 | 一种智能化全自动血样预处理仪器 |
| AT527700A1 (de) * | 2023-11-10 | 2025-05-15 | Meon Medical Solutions Gmbh & Co Kg | Analysator mit Kühleinrichtung |
| CN119216118B (zh) * | 2024-07-29 | 2025-04-29 | 青岛地质工程勘察院(青岛地质勘查开发局) | 一种水工环地质样品分离装置 |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0122772B1 (en) * | 1983-04-15 | 1988-08-17 | Science and Technology Agency, Minister's Secretariat, Director of Finance Division | Chemical manipulator |
| JPS61139756A (ja) | 1984-12-12 | 1986-06-27 | Hitachi Koki Co Ltd | 遠心式自動反応装置 |
| US4738825A (en) * | 1985-02-27 | 1988-04-19 | Fisher Scientific Company | Cuvette handling |
| US4708886A (en) | 1985-02-27 | 1987-11-24 | Fisher Scientific Company | Analysis system |
| JPS62192659A (ja) * | 1986-02-20 | 1987-08-24 | Nitsuteku:Kk | 自動分析装置 |
| JPH068785B2 (ja) | 1989-06-15 | 1994-02-02 | 株式会社テイエルブイ | 湿度計測装置 |
| JPH03175362A (ja) | 1989-09-13 | 1991-07-30 | Chiyoda Seisakusho:Kk | 自動細胞処理装置 |
| US5167926A (en) * | 1989-09-13 | 1992-12-01 | Kabushiki Kaisha Tiyoda Seisakusho | Apparatus for pretreating cells for flow cytometry |
| CA2156752C (en) * | 1993-02-25 | 1999-01-05 | Young Ran Kim | Multipurpose reagent system for rapid lysis of whole blood samples |
| JPH06281655A (ja) * | 1993-03-25 | 1994-10-07 | Olympus Optical Co Ltd | 自動分析装置 |
| JP3325338B2 (ja) * | 1993-04-27 | 2002-09-17 | プレシジョン・システム・サイエンス株式会社 | 検体検査装置 |
| US6709869B2 (en) * | 1995-12-18 | 2004-03-23 | Tecan Trading Ag | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system |
| JP4566299B2 (ja) | 1998-04-09 | 2010-10-20 | シスメックス株式会社 | 赤芽球の分類計数方法 |
| JP2000266764A (ja) | 1999-03-18 | 2000-09-29 | Hitachi Ltd | 分注用装置 |
| US6432365B1 (en) | 2000-04-14 | 2002-08-13 | Discovery Partners International, Inc. | System and method for dispensing solution to a multi-well container |
| WO2002025280A1 (en) | 2000-09-20 | 2002-03-28 | Surromed, Inc. | Method for monitoring resting and activated platelets in unfixed blood samples |
| US20030091473A1 (en) * | 2001-02-08 | 2003-05-15 | Downs Robert Charles | Automated centrifuge and method of using same |
| JP2004309145A (ja) * | 2003-04-02 | 2004-11-04 | Hitachi High-Technologies Corp | 化学分析装置及び化学分析用構造体 |
| US7354773B2 (en) | 2003-05-14 | 2008-04-08 | Beckman Coulter, Inc. | Method and apparatus for preparing cell samples for intracellular antigen detection using flow cytometry |
| EP2295982B1 (en) | 2005-09-26 | 2018-09-05 | QIAGEN GmbH | Apparatus for processing biological material |
| CN1963527B (zh) * | 2005-11-10 | 2011-12-14 | 深圳迈瑞生物医疗电子股份有限公司 | 全自动生化分析仪及其分析方法 |
| EP2047282B1 (en) | 2006-07-28 | 2014-05-07 | Qiagen GmbH | Device for processing samples |
| JP4911434B2 (ja) * | 2007-06-21 | 2012-04-04 | 日立工機株式会社 | 細胞洗浄遠心機およびそれに用いられる細胞洗浄ロータ |
| JP2009270845A (ja) | 2008-04-30 | 2009-11-19 | Nippon Koden Corp | 診断装置及び診断システム |
| US7999937B1 (en) * | 2008-05-13 | 2011-08-16 | Sandia Corporation | Microfluidic devices and methods for integrated flow cytometry |
| JP2010085249A (ja) * | 2008-09-30 | 2010-04-15 | Olympus Corp | 自動分析装置、試薬補充装置および試薬オートローディング方法 |
| US9034257B2 (en) * | 2008-10-27 | 2015-05-19 | Nodality, Inc. | High throughput flow cytometry system and method |
| US10288632B2 (en) * | 2009-09-21 | 2019-05-14 | Pocared Diagnostics Ltd. | System for conducting the identification of bacteria in biological samples |
| JP5502655B2 (ja) * | 2009-09-30 | 2014-05-28 | シスメックス株式会社 | 試料調製装置、細胞分析装置及び分析物の濃縮方法 |
| JP5728196B2 (ja) * | 2010-01-21 | 2015-06-03 | シスメックス株式会社 | 試料調製装置および試料調製方法 |
| US9753048B2 (en) | 2010-05-24 | 2017-09-05 | Hitachi High-Technologies Corporation | Sample test automation system |
| JP5626727B2 (ja) * | 2010-09-21 | 2014-11-19 | 国立大学法人東京農工大学 | 微量血液からの白血球ポピュレーション解析法 |
| FR2973109B1 (fr) | 2011-03-22 | 2013-05-10 | Univ Nantes | Methode cytologique utilisant l'autofluorescence des globules blancs pour le diagnostic precoce et le suivi des infections |
| US8840838B2 (en) * | 2011-09-25 | 2014-09-23 | Theranos, Inc. | Centrifuge configurations |
| US9632102B2 (en) * | 2011-09-25 | 2017-04-25 | Theranos, Inc. | Systems and methods for multi-purpose analysis |
| CN108490204A (zh) * | 2011-09-25 | 2018-09-04 | 赛拉诺斯知识产权有限责任公司 | 用于多重分析的系统和方法 |
| JP5912034B2 (ja) | 2011-11-28 | 2016-04-27 | 公益財団法人神奈川科学技術アカデミー | 液体還流型高速遺伝子増幅装置 |
| MX353212B (es) | 2011-12-07 | 2018-01-08 | Cytovera Inc | Metodo y dispositivo para el procesamiento de muestras. |
| CN104272083B (zh) * | 2012-02-24 | 2018-01-02 | 英士查诺尔有限公司 | 用于预处理细胞的系统、设备和装置 |
| US9835612B2 (en) * | 2012-12-26 | 2017-12-05 | Hitachi High-Technologies Corporation | Automatic analyzer |
| JP2014209090A (ja) * | 2013-03-29 | 2014-11-06 | シスメックス株式会社 | 細胞分析方法及び装置 |
| US20140371047A1 (en) * | 2013-06-18 | 2014-12-18 | L.U.M. Gmbh | Centrifuge rotor |
| EP2857844B1 (de) * | 2013-10-07 | 2021-12-01 | Eppendorf AG | Laborgerät, System und Verfahren zur gerätegesteuerten Behandlung mindestens einer Laborprobe unter Verwendung mindestens eines Verbrauchsartikels |
| JP6130320B2 (ja) * | 2014-03-28 | 2017-05-17 | シスメックス株式会社 | 検体分析装置および試薬容器 |
-
2016
- 2016-12-15 JP JP2016243860A patent/JP6937116B2/ja active Active
-
2017
- 2017-12-07 CN CN202210846699.8A patent/CN115267234A/zh active Pending
- 2017-12-07 CN CN201711283284.XA patent/CN108226551B/zh active Active
- 2017-12-13 EP EP17206975.9A patent/EP3336517A1/en not_active Withdrawn
- 2017-12-14 US US15/842,470 patent/US11099200B2/en active Active
-
2021
- 2021-07-12 US US17/373,495 patent/US20210333299A1/en not_active Abandoned
- 2021-08-27 JP JP2021139222A patent/JP7223085B2/ja active Active
-
2023
- 2023-02-03 JP JP2023015226A patent/JP7503160B2/ja active Active
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