JP2018048151A5 - - Google Patents
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- Publication number
- JP2018048151A5 JP2018048151A5 JP2017192907A JP2017192907A JP2018048151A5 JP 2018048151 A5 JP2018048151 A5 JP 2018048151A5 JP 2017192907 A JP2017192907 A JP 2017192907A JP 2017192907 A JP2017192907 A JP 2017192907A JP 2018048151 A5 JP2018048151 A5 JP 2018048151A5
- Authority
- JP
- Japan
- Prior art keywords
- inhibitor
- cancer stem
- brain tumor
- pharmaceutical composition
- stem cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10185930A EP2446895A1 (en) | 2010-10-01 | 2010-10-01 | EPH receptor expression in tumor stem cells |
| EP10185930.4 | 2010-10-01 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015200808A Division JP6523910B2 (ja) | 2010-10-01 | 2015-10-09 | 腫瘍幹細胞におけるｅｐｈ受容体発現 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019205190A Division JP2020037579A (ja) | 2010-10-01 | 2019-11-13 | 腫瘍幹細胞におけるｅｐｈ受容体発現 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018048151A JP2018048151A (ja) | 2018-03-29 |
| JP2018048151A5 true JP2018048151A5 (https=) | 2018-05-17 |
| JP6618968B2 JP6618968B2 (ja) | 2019-12-11 |
Family
ID=43856109
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013530753A Pending JP2013540117A (ja) | 2010-10-01 | 2011-09-30 | 腫瘍幹細胞におけるｅｐｈ受容体発現 |
| JP2015200808A Active JP6523910B2 (ja) | 2010-10-01 | 2015-10-09 | 腫瘍幹細胞におけるｅｐｈ受容体発現 |
| JP2017192907A Active JP6618968B2 (ja) | 2010-10-01 | 2017-10-02 | 腫瘍幹細胞におけるｅｐｈ受容体発現 |
| JP2019205190A Pending JP2020037579A (ja) | 2010-10-01 | 2019-11-13 | 腫瘍幹細胞におけるｅｐｈ受容体発現 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013530753A Pending JP2013540117A (ja) | 2010-10-01 | 2011-09-30 | 腫瘍幹細胞におけるｅｐｈ受容体発現 |
| JP2015200808A Active JP6523910B2 (ja) | 2010-10-01 | 2015-10-09 | 腫瘍幹細胞におけるｅｐｈ受容体発現 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019205190A Pending JP2020037579A (ja) | 2010-10-01 | 2019-11-13 | 腫瘍幹細胞におけるｅｐｈ受容体発現 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9078857B2 (https=) |
| EP (2) | EP2446895A1 (https=) |
| JP (4) | JP2013540117A (https=) |
| KR (2) | KR101719966B1 (https=) |
| AU (1) | AU2011310109B2 (https=) |
| CA (1) | CA2813101C (https=) |
| DK (1) | DK2621513T3 (https=) |
| ES (1) | ES2616444T3 (https=) |
| NZ (1) | NZ609594A (https=) |
| PL (1) | PL2621513T3 (https=) |
| WO (1) | WO2012042021A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012118547A1 (en) | 2010-12-08 | 2012-09-07 | Stem Centrx, Inc. | Novel modulators and methods of use |
| SA112330278B1 (ar) | 2011-02-18 | 2015-10-09 | ستيم سينتركس، انك. | مواد ضابطة جديدة وطرق للاستخدام |
| EP2733206A1 (en) * | 2012-11-19 | 2014-05-21 | Naroa LLC | Method for the isolation for mammalian stem cells using EphA2 and uses thereof |
| CN105828841A (zh) | 2013-11-04 | 2016-08-03 | 辉瑞大药厂 | 抗-efna4抗体-药物缀合物 |
| US9777070B2 (en) | 2014-04-30 | 2017-10-03 | Pfizer Inc | Anti-PTK7 antibody-drug conjugates |
| JP6921755B2 (ja) | 2014-12-10 | 2021-08-18 | ハイパーステム ソシエテ アノニム | 脳腫瘍幹細胞の成長、遊走および浸潤性を低下させ脳腫瘍患者の生存率を改善する方法および組成物 |
| CN107851031B (zh) | 2015-05-08 | 2021-05-28 | 佛罗乔有限责任公司 | 数据发现节点 |
| IL289849B2 (en) | 2015-11-10 | 2024-01-01 | Nat Inst Biotechnology Negev Ltd | Means and methods for reducing tumorigenicity of cancer stem cells |
| JP7680047B2 (ja) * | 2020-03-31 | 2025-05-20 | 慶應義塾 | ゲノム編集多能性幹細胞を用いた治療薬 |
| WO2026022122A1 (en) * | 2024-07-23 | 2026-01-29 | Eos Research Sa | Checkpoint inhibitors in the treatment of glioblastoma multiforme |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004281834A1 (en) * | 2003-10-15 | 2005-04-28 | Cerus Corporation | Listeria-based EphA2 vaccines |
| EP1778726A4 (en) * | 2004-08-16 | 2009-03-18 | Medimmune Inc | INTEGRIN ANTAGONISTS WITH IMPROVED ANTIBODY-DEPENDENT CELL-ASSAYED CYTOTOXICITY ACTIVITY |
| US20070248628A1 (en) * | 2005-12-06 | 2007-10-25 | Keller Lorraine H | Immunogens in cancer stem cells |
| US8343461B2 (en) * | 2006-03-08 | 2013-01-01 | Wake Forest University Health Sciences | Molecular signature of cancer |
| HRP20170407T1 (hr) * | 2007-08-30 | 2017-05-05 | Daiichi Sankyo Company, Limited | Anti-epha2 anitijelo |
-
2010
- 2010-10-01 EP EP10185930A patent/EP2446895A1/en not_active Withdrawn
-
2011
- 2011-04-18 US US13/089,217 patent/US9078857B2/en active Active
- 2011-09-30 WO PCT/EP2011/067114 patent/WO2012042021A1/en not_active Ceased
- 2011-09-30 EP EP11778540.2A patent/EP2621513B1/en active Active
- 2011-09-30 KR KR1020167002577A patent/KR101719966B1/ko active Active
- 2011-09-30 KR KR1020137011310A patent/KR20130095286A/ko not_active Ceased
- 2011-09-30 ES ES11778540.2T patent/ES2616444T3/es active Active
- 2011-09-30 PL PL11778540T patent/PL2621513T3/pl unknown
- 2011-09-30 AU AU2011310109A patent/AU2011310109B2/en active Active
- 2011-09-30 JP JP2013530753A patent/JP2013540117A/ja active Pending
- 2011-09-30 DK DK11778540.2T patent/DK2621513T3/en active
- 2011-09-30 NZ NZ609594A patent/NZ609594A/en unknown
- 2011-09-30 CA CA2813101A patent/CA2813101C/en active Active
-
2015
- 2015-10-09 JP JP2015200808A patent/JP6523910B2/ja active Active
-
2017
- 2017-10-02 JP JP2017192907A patent/JP6618968B2/ja active Active
-
2019
- 2019-11-13 JP JP2019205190A patent/JP2020037579A/ja active Pending
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