JP2015512447A5 - - Google Patents

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Publication number
JP2015512447A5
JP2015512447A5 JP2015504647A JP2015504647A JP2015512447A5 JP 2015512447 A5 JP2015512447 A5 JP 2015512447A5 JP 2015504647 A JP2015504647 A JP 2015504647A JP 2015504647 A JP2015504647 A JP 2015504647A JP 2015512447 A5 JP2015512447 A5 JP 2015512447A5
Authority
JP
Japan
Prior art keywords
tyrosine kinase
inhibitor
fgfr
pharmaceutically acceptable
met
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2015504647A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015512447A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/034759 external-priority patent/WO2013151913A1/en
Publication of JP2015512447A publication Critical patent/JP2015512447A/ja
Publication of JP2015512447A5 publication Critical patent/JP2015512447A5/ja
Pending legal-status Critical Current

Links

JP2015504647A 2012-04-03 2013-04-01 チロシンキナーゼ阻害薬の組合せおよびその使用 Pending JP2015512447A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261619502P 2012-04-03 2012-04-03
US61/619,502 2012-04-03
PCT/US2013/034759 WO2013151913A1 (en) 2012-04-03 2013-04-01 Tyrosine kinase inhibitor combinations and their use

Publications (2)

Publication Number Publication Date
JP2015512447A JP2015512447A (ja) 2015-04-27
JP2015512447A5 true JP2015512447A5 (https=) 2016-05-19

Family

ID=48184451

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015504647A Pending JP2015512447A (ja) 2012-04-03 2013-04-01 チロシンキナーゼ阻害薬の組合せおよびその使用

Country Status (11)

Country Link
US (1) US20150051210A1 (https=)
EP (1) EP2833917A1 (https=)
JP (1) JP2015512447A (https=)
KR (1) KR20140146086A (https=)
CN (1) CN104244982A (https=)
AU (1) AU2013243737B2 (https=)
CA (1) CA2866321A1 (https=)
IN (1) IN2014DN07410A (https=)
MX (1) MX2014011987A (https=)
RU (1) RU2014143213A (https=)
WO (1) WO2013151913A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6752715B2 (ja) 2014-03-26 2020-09-09 アステックス、セラピューティックス、リミテッドAstex Therapeutics Limited 組合せ
ES2831416T3 (es) * 2014-07-31 2021-06-08 Novartis Ag Terapia de combinación de un inhibidor de MET y un inhibidor de EGFR
ES2887148T3 (es) 2015-03-25 2021-12-21 Nat Cancer Ct Agente terapéutico contra el cáncer de vías biliares
US12414945B2 (en) 2015-12-17 2025-09-16 Eisai R&D Management Co., Ltd. Therapeutic agent for breast cancer

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0512324D0 (en) 2005-06-16 2005-07-27 Novartis Ag Organic compounds
DE102005038537A1 (de) 2005-08-16 2007-02-22 Merck Patent Gmbh 1-Acyldihydropyrazolderivate
HUE030390T2 (en) 2005-12-21 2017-05-29 Janssen Pharmaceutica Nv Triazolopyridazines as tyrosine kinase modulators
NL2000613C2 (nl) 2006-05-11 2007-11-20 Pfizer Prod Inc Triazoolpyrazinederivaten.
PE20080403A1 (es) 2006-07-14 2008-04-25 Amgen Inc Derivados heterociclicos fusionados y metodos de uso
AU2007309149C1 (en) 2006-10-23 2013-04-04 Sgx Pharmaceuticals, Inc. Bicyclic triazoles as protein kinase modulators
ME02372B (me) * 2006-11-22 2016-06-20 Incyte Holdings Corp Imidazotriazini i imidazopiramidini kao inhibitori kinaze
JP4994044B2 (ja) * 2007-01-05 2012-08-08 シェブロンジャパン株式会社 潤滑油組成物
CA2683559C (en) * 2007-04-13 2019-09-24 Dana Farber Cancer Institute, Inc. Methods for treating cancer resistant to erbb therapeutics
CA2720888A1 (en) * 2008-04-29 2009-11-05 Novartis Ag Methods of monitoring the modulation of the kinase activity of fibroblast growth factor receptor and uses of said methods
EP2288383A1 (en) * 2008-05-14 2011-03-02 Amgen, Inc Combinations vegf(r) inhibitors and hepatocyte growth factor (c-met) inhibitors for the treatment of cancer
JP5781510B2 (ja) 2009-08-12 2015-09-24 ノバルティス アーゲー ヘテロ環式ヒドラゾン化合物および癌および炎症の処置のためのそれらの使用
EP2621483A1 (en) * 2010-09-27 2013-08-07 Exelixis, Inc. Dual inhibitors of met and vegf for the treatment of castration resistant prostate cancer and osteoblastic bone metastases

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