JP2017538692A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017538692A5 JP2017538692A5 JP2017528156A JP2017528156A JP2017538692A5 JP 2017538692 A5 JP2017538692 A5 JP 2017538692A5 JP 2017528156 A JP2017528156 A JP 2017528156A JP 2017528156 A JP2017528156 A JP 2017528156A JP 2017538692 A5 JP2017538692 A5 JP 2017538692A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- nitrogen
- alkyl
- carbon
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1421020.7 | 2014-11-26 | ||
| GBGB1421020.7A GB201421020D0 (en) | 2014-11-26 | 2014-11-26 | Compounds |
| GB1516059.1 | 2015-09-10 | ||
| GBGB1516059.1A GB201516059D0 (en) | 2015-09-10 | 2015-09-10 | Compounds |
| PCT/EP2015/077821 WO2016083531A1 (en) | 2014-11-26 | 2015-11-26 | Compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017538692A JP2017538692A (ja) | 2017-12-28 |
| JP2017538692A5 true JP2017538692A5 (enExample) | 2019-01-17 |
| JP7349773B2 JP7349773B2 (ja) | 2023-09-25 |
Family
ID=54705181
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017528156A Active JP7349773B2 (ja) | 2014-11-26 | 2015-11-26 | 化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US12146004B2 (enExample) |
| EP (1) | EP3224273A1 (enExample) |
| JP (1) | JP7349773B2 (enExample) |
| CN (1) | CN107108699A (enExample) |
| AU (1) | AU2015352440B2 (enExample) |
| CA (1) | CA2968902C (enExample) |
| TW (1) | TWI757229B (enExample) |
| WO (1) | WO2016083531A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3224273A1 (en) * | 2014-11-26 | 2017-10-04 | New Pharma Licence Holdings Limited | Compounds |
| WO2018006063A1 (en) * | 2016-07-01 | 2018-01-04 | Cidara Therapeutics, Inc. | Compositions and methods for the treatment of bacterial infections |
| AU2017376711B2 (en) * | 2016-12-16 | 2020-07-16 | Institute Of Medicinal Biotechnology, Chinese Academy Of Medical Sciences | Polymyxin derivative, preparation method and application thereof |
| US11279733B2 (en) | 2017-11-02 | 2022-03-22 | The University Of Queensland | Peptide antibiotics |
| PL3810633T3 (pl) * | 2018-06-25 | 2024-04-08 | Spero Therapeutics, Inc. | Związki |
| CN111690040A (zh) * | 2019-03-12 | 2020-09-22 | 上海来益生物药物研究开发中心有限责任公司 | 多粘菌素衍生物、其制备方法和应用 |
| WO2021150792A1 (en) | 2020-01-21 | 2021-07-29 | Micurx Pharmaceuticals, Inc. | Novel compounds and composition for targeted therapy of kidney-associated cancers |
| CN111559992B (zh) * | 2020-05-29 | 2022-04-08 | 华中科技大学 | 一种2-芳基-γ-氨基丁酸衍生物的制备方法 |
| TW202233649A (zh) | 2020-11-06 | 2022-09-01 | 美商斯佩羅治療學股份有限公司 | 化合物 |
| WO2022206826A1 (zh) * | 2021-03-31 | 2022-10-06 | 江苏奥赛康药业有限公司 | 一种多粘菌素衍生物的硫酸盐及其药物组合物 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2128617A (en) | 1982-10-06 | 1984-05-02 | Martti Vaara | Polypeptides for use in antibacterial therapy |
| AU7753787A (en) | 1986-08-06 | 1988-02-24 | Jean-Luc Fauchere | Production of covalent-linked conjugates from an antibiotic and a non-toxic derivative of polymyxine b |
| US20010021697A1 (en) | 1987-09-14 | 2001-09-13 | Henning Lowenstein | Methods and compositions for the treatment of mammalian infections employing medicaments comprising hymenoptera venom, proteinageous or polypeptide components thereof, or analogues of such proteinaceous or polypeptide components |
| TW274552B (enExample) | 1992-05-26 | 1996-04-21 | Hoechst Ag | |
| US5767068A (en) | 1997-02-13 | 1998-06-16 | Pathogenesis Corporation | Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections |
| CA2540742A1 (en) | 2003-09-30 | 2005-04-14 | Terry Hicks | Compositions and methods for treating burns |
| US20060004185A1 (en) | 2004-07-01 | 2006-01-05 | Leese Richard A | Peptide antibiotics and peptide intermediates for their prepartion |
| CN103059106B (zh) | 2006-08-11 | 2015-01-14 | 北方抗生素有限公司 | 多粘菌素衍生物及其用途 |
| US7807637B2 (en) * | 2006-08-11 | 2010-10-05 | Northern Antibiotics Oy | Polymyxin derivatives and uses thereof |
| US8329645B2 (en) | 2008-02-08 | 2012-12-11 | Northern Antibiotics Ltd. | Polymyxin derivatives and uses thereof |
| FI20085469A0 (fi) | 2008-02-08 | 2008-05-16 | Northern Antibiotics Oy | Polymyksiinijohdannaiset, joissa on lyhyt rasvahappohäntä, ja niiden käyttöjä |
| US8193148B2 (en) | 2008-02-08 | 2012-06-05 | Northern Antibiotics Ltd. | Short fatty acid tail polymyxin derivatives and uses thereof |
| ES2334547B1 (es) | 2008-09-10 | 2010-12-03 | Universidad De Barcelona | Compuestos peptidicos antibacterianos. |
| US8343912B2 (en) | 2008-12-23 | 2013-01-01 | Biosource Pharm, Inc. | Antibiotic compositions for the treatment of gram negative infections |
| CN101851270A (zh) | 2009-04-03 | 2010-10-06 | 梁浩 | 一种多粘菌素衍生物及其制备方法 |
| WO2010130007A1 (en) * | 2009-05-14 | 2010-11-18 | Monash University | Antimicrobial compounds |
| US8415307B1 (en) | 2010-06-23 | 2013-04-09 | Biosource Pharm, Inc. | Antibiotic compositions for the treatment of gram negative infections |
| WO2012051663A1 (en) * | 2010-10-21 | 2012-04-26 | Monash University | Antimicrobial compounds |
| WO2012168820A1 (en) * | 2011-06-08 | 2012-12-13 | Pfizer Inc. | Polymyxin derivatives useful as antibacterial agents |
| WO2013072695A1 (en) * | 2011-11-18 | 2013-05-23 | Novacta Biosystems Limited | Polymyxin derivatives |
| PL2999711T3 (pl) | 2013-05-22 | 2022-09-26 | Spero Therapeutics, Inc. | Pochodne polimyksyny i ich zastosowanie w terapii skojarzonej razem z różnymi antybiotykami |
| LT3116897T (lt) | 2014-03-11 | 2022-05-10 | Spero Therapeutics, Inc. | Polimiksino dariniai ir jų panaudojimas kompleksinėje terapijoje kartu su skirtingais antibiotikais |
| US10047126B2 (en) | 2014-04-01 | 2018-08-14 | Monash University | Polymyxin derivatives as antimicrobial compounds |
| EP3224273A1 (en) * | 2014-11-26 | 2017-10-04 | New Pharma Licence Holdings Limited | Compounds |
| WO2016166103A1 (en) | 2015-04-13 | 2016-10-20 | Xellia Pharmaceuticals Aps | Polymyxin derivatives |
| AU2016331658B2 (en) | 2015-09-29 | 2021-04-01 | Monash University | Antimicrobial polymyxin derivative compounds |
| PL3810633T3 (pl) | 2018-06-25 | 2024-04-08 | Spero Therapeutics, Inc. | Związki |
-
2015
- 2015-11-26 EP EP15801162.7A patent/EP3224273A1/en not_active Withdrawn
- 2015-11-26 CA CA2968902A patent/CA2968902C/en active Active
- 2015-11-26 AU AU2015352440A patent/AU2015352440B2/en active Active
- 2015-11-26 US US15/529,786 patent/US12146004B2/en active Active
- 2015-11-26 JP JP2017528156A patent/JP7349773B2/ja active Active
- 2015-11-26 TW TW104139459A patent/TWI757229B/zh not_active IP Right Cessation
- 2015-11-26 WO PCT/EP2015/077821 patent/WO2016083531A1/en not_active Ceased
- 2015-11-26 CN CN201580072906.7A patent/CN107108699A/zh active Pending
-
2023
- 2023-04-25 US US18/139,030 patent/US20230340026A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017538692A5 (enExample) | ||
| CN1037683C (zh) | 一种三唑基硫甲基硫代头孢菌素氢氯化物的结晶水合物及其制备和其药物组合物 | |
| Kashyap et al. | Review on synthetic chemistry and antibacterial importance of thiazole derivatives | |
| JP5576485B2 (ja) | 新生物疾患又は自己免疫疾患を処置するためのプロドラッグとしてのフラザノベンゾイミダゾール | |
| JP5161269B2 (ja) | 架橋されたグリコペプチド−セファロスポリン抗生物質 | |
| AU2010339841B2 (en) | Compound suitable for the treatment of synucleopathies | |
| Drewry et al. | Solid-phase synthesis of trisubstituted guanidines | |
| US20130123196A1 (en) | Thioether-, ether-, and alkylamine-linked hydrogen bond surrogate peptidomimetics | |
| JP5791150B2 (ja) | 血管内皮リパーゼ阻害活性を有するオキサジアゾール誘導体 | |
| US20080153743A1 (en) | Methods relating to the treatment of fibrosis | |
| US20110224130A1 (en) | Cross-linked glycopeptide-cephalosporin antibiotics | |
| WO1998000153A1 (en) | Amides | |
| CN105377304B (zh) | 鹅膏毒肽衍生物 | |
| JP2017538692A (ja) | 化合物 | |
| WO2023038088A1 (ja) | トリスルフィド化合物を用いる、肝細胞増殖因子中のチロシン残基のニトロ化を防止する方法 | |
| BRPI0213154B1 (pt) | Compostos de glicopeptídeo cefalosporina de ligação reticulada, composição farmacêutica de tais compostos e seu uso | |
| JP3065289B2 (ja) | ビニルピロリジノンセファロスポリン誘導体類 | |
| JP2000509030A (ja) | グリコペプチド化合物 | |
| CA2991521A1 (en) | Process for preparing ceftolozane from 7-aminocephalosporanic acid (7-aca) | |
| JP3152934B2 (ja) | 新規セフェム誘導体 | |
| EP3947416A1 (en) | Peptides and compounds that bind to elongation initiation factor 4e | |
| FI73221B (fi) | Foerfarande foer framstaellning av nya 7-/2-(2-amino-4-tiazolyl)oxiiminoacetamido/-3-cefem-3-heterocyklyltio- metyl-4-karboksylsyra-1-s-oxider. | |
| JP2021505542A5 (enExample) | ||
| JPWO2020002325A5 (enExample) | ||
| JPS6228154B2 (enExample) |