JP2017537643A5 - - Google Patents
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- JP2017537643A5 JP2017537643A5 JP2017532046A JP2017532046A JP2017537643A5 JP 2017537643 A5 JP2017537643 A5 JP 2017537643A5 JP 2017532046 A JP2017532046 A JP 2017532046A JP 2017532046 A JP2017532046 A JP 2017532046A JP 2017537643 A5 JP2017537643 A5 JP 2017537643A5
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- JP
- Japan
- Prior art keywords
- seq
- nucleic acid
- bacteriophage
- viral
- acid sequence
- Prior art date
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462092707P | 2014-12-16 | 2014-12-16 | |
| US62/092,707 | 2014-12-16 | ||
| US201562102362P | 2015-01-12 | 2015-01-12 | |
| US62/102,362 | 2015-01-12 | ||
| US201562242811P | 2015-10-16 | 2015-10-16 | |
| US62/242,811 | 2015-10-16 | ||
| PCT/US2015/065891 WO2016100389A1 (en) | 2014-12-16 | 2015-12-15 | Compositions of and methods for in vitro viral genome engineering |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021024982A Division JP7133671B2 (ja) | 2014-12-16 | 2021-02-19 | インビトロウイルスゲノム工学のための組成物及びその方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017537643A JP2017537643A (ja) | 2017-12-21 |
| JP2017537643A5 true JP2017537643A5 (https=) | 2019-01-31 |
| JP6842417B2 JP6842417B2 (ja) | 2021-03-17 |
Family
ID=56127485
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017532046A Active JP6842417B2 (ja) | 2014-12-16 | 2015-12-15 | インビトロウイルスゲノム工学のための組成物及びその方法 |
| JP2021024982A Active JP7133671B2 (ja) | 2014-12-16 | 2021-02-19 | インビトロウイルスゲノム工学のための組成物及びその方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021024982A Active JP7133671B2 (ja) | 2014-12-16 | 2021-02-19 | インビトロウイルスゲノム工学のための組成物及びその方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US10221398B2 (https=) |
| EP (2) | EP3234136B1 (https=) |
| JP (2) | JP6842417B2 (https=) |
| CN (2) | CN113215115B (https=) |
| AU (2) | AU2015362618B2 (https=) |
| CA (2) | CA3254091A1 (https=) |
| EA (1) | EA038595B1 (https=) |
| ES (1) | ES2991077T3 (https=) |
| WO (1) | WO2016100389A1 (https=) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101801521B (zh) | 2007-05-14 | 2015-06-17 | 纽约州立大学研究基金会 | 生物膜中细菌细胞内的生理学分散响应诱导 |
| JP6261500B2 (ja) | 2011-07-22 | 2018-01-17 | プレジデント アンド フェローズ オブ ハーバード カレッジ | ヌクレアーゼ切断特異性の評価および改善 |
| US20150044192A1 (en) | 2013-08-09 | 2015-02-12 | President And Fellows Of Harvard College | Methods for identifying a target site of a cas9 nuclease |
| US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
| US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
| US9388430B2 (en) | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
| US9340799B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | MRNA-sensing switchable gRNAs |
| US20150165054A1 (en) | 2013-12-12 | 2015-06-18 | President And Fellows Of Harvard College | Methods for correcting caspase-9 point mutations |
| HUE049405T2 (hu) | 2014-06-23 | 2020-09-28 | Regeneron Pharma | Nukleáz-közvetített DNS-összeállítás |
| WO2016022363A2 (en) | 2014-07-30 | 2016-02-11 | President And Fellows Of Harvard College | Cas9 proteins including ligand-dependent inteins |
| EP3234136B1 (en) | 2014-12-16 | 2024-08-21 | C3J Therapeutics, Inc. | Compositions of and methods for in vitro viral genome engineering |
| US20160362667A1 (en) * | 2015-06-10 | 2016-12-15 | Caribou Biosciences, Inc. | CRISPR-Cas Compositions and Methods |
| US10513732B2 (en) * | 2015-07-13 | 2019-12-24 | New York University | Sequencing methods and kits |
| JP7109784B2 (ja) | 2015-10-23 | 2022-08-01 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 遺伝子編集のための進化したＣａｓ９蛋白質 |
| US10136820B2 (en) * | 2015-12-21 | 2018-11-27 | Gholam A. Peyman | Method to visualize very early stage neoplasm or other lesions |
| US11433260B2 (en) | 2015-12-21 | 2022-09-06 | Gholam A. Peyman | Cancer treatment methods using thermotherapy and/or enhanced immunotherapy |
| WO2017172645A2 (en) * | 2016-03-28 | 2017-10-05 | The Charles Stark Draper Laboratory, Inc. | Bacteriophage engineering methods |
| KR102547316B1 (ko) | 2016-08-03 | 2023-06-23 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 아데노신 핵염기 편집제 및 그의 용도 |
| US11661590B2 (en) | 2016-08-09 | 2023-05-30 | President And Fellows Of Harvard College | Programmable CAS9-recombinase fusion proteins and uses thereof |
| US11542509B2 (en) | 2016-08-24 | 2023-01-03 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
| DK3503915T5 (da) | 2016-08-26 | 2024-09-02 | Telesis Bio Inc | Genetisk modificerede Vibro natriegen |
| EP3526320A1 (en) | 2016-10-14 | 2019-08-21 | President and Fellows of Harvard College | Aav delivery of nucleobase editors |
| WO2018071841A1 (en) * | 2016-10-14 | 2018-04-19 | The Forsyth Institute | Compositions and methods for evading bacterial defense mechanisms |
| WO2018119359A1 (en) | 2016-12-23 | 2018-06-28 | President And Fellows Of Harvard College | Editing of ccr5 receptor gene to protect against hiv infection |
| WO2018148412A1 (en) | 2017-02-09 | 2018-08-16 | The Charles Stark Draper Laboratory Inc. | Recombinant k1-5 bacteriophages and uses thereof |
| EP3592846A1 (en) | 2017-03-06 | 2020-01-15 | Massachusetts Institute of Technology | Methods of cloning prophages and producing lytic phage particles |
| JP2020510038A (ja) | 2017-03-09 | 2020-04-02 | プレジデント アンド フェローズ オブ ハーバード カレッジ | がんワクチン |
| EP3592853A1 (en) | 2017-03-09 | 2020-01-15 | President and Fellows of Harvard College | Suppression of pain by gene editing |
| JP2020510439A (ja) | 2017-03-10 | 2020-04-09 | プレジデント アンド フェローズ オブ ハーバード カレッジ | シトシンからグアニンへの塩基編集因子 |
| CA3057192A1 (en) | 2017-03-23 | 2018-09-27 | President And Fellows Of Harvard College | Nucleobase editors comprising nucleic acid programmable dna binding proteins |
| WO2018209320A1 (en) | 2017-05-12 | 2018-11-15 | President And Fellows Of Harvard College | Aptazyme-embedded guide rnas for use with crispr-cas9 in genome editing and transcriptional activation |
| WO2018222891A1 (en) * | 2017-06-01 | 2018-12-06 | The Charles Stark Draper Laboratory Inc. | Phage engineering: protection by circularized intermediate |
| WO2019023680A1 (en) | 2017-07-28 | 2019-01-31 | President And Fellows Of Harvard College | METHODS AND COMPOSITIONS FOR EVOLUTION OF BASIC EDITORS USING PHAGE-ASSISTED CONTINUOUS EVOLUTION (PACE) |
| US10174295B1 (en) * | 2017-08-01 | 2019-01-08 | The Charles Stark Draper Laboratory, Inc. | Composition of matter: engineering of Escherichia coli phage K1E |
| WO2019032576A2 (en) * | 2017-08-08 | 2019-02-14 | The Charles Stark Draper Laboratory Inc. | HANDLING OF BACTERIOPHAGES BY SEMI-SYNTHESIS |
| EP3676376B1 (en) | 2017-08-30 | 2025-01-15 | President and Fellows of Harvard College | High efficiency base editors comprising gam |
| KR20250107288A (ko) | 2017-10-16 | 2025-07-11 | 더 브로드 인스티튜트, 인코퍼레이티드 | 아데노신 염기 편집제의 용도 |
| WO2019118949A1 (en) | 2017-12-15 | 2019-06-20 | The Broad Institute, Inc. | Systems and methods for predicting repair outcomes in genetic engineering |
| CN112236517A (zh) * | 2018-05-22 | 2021-01-15 | 学校法人自治医科大学 | 抗菌噬菌体、治疗用组合物、杀菌剂、食品、细菌鉴别试剂盒、治疗用组合物制造方法、细菌去除方法、细菌鉴别方法及动物治疗方法 |
| EP3797160A1 (en) | 2018-05-23 | 2021-03-31 | The Broad Institute Inc. | Base editors and uses thereof |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| US12522807B2 (en) | 2018-07-09 | 2026-01-13 | The Broad Institute, Inc. | RNA programmable epigenetic RNA modifiers and uses thereof |
| WO2020092453A1 (en) | 2018-10-29 | 2020-05-07 | The Broad Institute, Inc. | Nucleobase editors comprising geocas9 and uses thereof |
| WO2020092748A1 (en) * | 2018-11-01 | 2020-05-07 | The Trustees Of Princeton University | System for protein inactivation and recombinant phages for targeted bacterial killing, infection, biodetection, and as a means of protein extraction |
| EP4374923A3 (en) * | 2018-11-27 | 2024-08-14 | Eligo Bioscience | Chimeric receptor binding proteins for use in bacterial delivery vehicles |
| KR20210107053A (ko) * | 2018-12-21 | 2021-08-31 | 엘리고 바이오사이언스 | 박테리아 전달 비히클에서 사용을 위한 분지형 수용체 결합 다수-서브유닛 단백질 복합체 |
| US12351837B2 (en) | 2019-01-23 | 2025-07-08 | The Broad Institute, Inc. | Supernegatively charged proteins and uses thereof |
| WO2020163655A1 (en) | 2019-02-06 | 2020-08-13 | Fred Hutchinson Cancer Research Center | Minicircle producing bacteria engineered to differentially methylate nucleic acid molecules therein |
| JP7657726B2 (ja) | 2019-03-19 | 2025-04-07 | ザ ブロード インスティテュート，インコーポレーテッド | 編集ヌクレオチド配列を編集するための方法および組成物 |
| WO2020206134A1 (en) | 2019-04-04 | 2020-10-08 | Regeneron Pharmaceuticals, Inc. | Methods for scarless introduction of targeted modifications into targeting vectors |
| US12473543B2 (en) | 2019-04-17 | 2025-11-18 | The Broad Institute, Inc. | Adenine base editors with reduced off-target effects |
| US12435330B2 (en) | 2019-10-10 | 2025-10-07 | The Broad Institute, Inc. | Methods and compositions for prime editing RNA |
| DE112021002672T5 (de) | 2020-05-08 | 2023-04-13 | President And Fellows Of Harvard College | Vefahren und zusammensetzungen zum gleichzeitigen editieren beider stränge einer doppelsträngigen nukleotid-zielsequenz |
| CN114540389B (zh) * | 2020-11-26 | 2024-05-14 | 深圳华大生命科学研究院 | 一种制备基因工程病毒的方法及其应用 |
| CN112778399A (zh) * | 2021-01-21 | 2021-05-11 | 南开大学 | 一类源自毒性淀粉样纤维纳米抗菌肽的制备及性质表征方法 |
| JP2022117439A (ja) * | 2021-01-29 | 2022-08-10 | 学校法人立教学院 | インビトロパッケージングを用いた多断片ｄｎａの連結および細胞内導入方法 |
| WO2022251644A1 (en) | 2021-05-28 | 2022-12-01 | Lyell Immunopharma, Inc. | Nr4a3-deficient immune cells and uses thereof |
| KR20240027676A (ko) | 2021-06-02 | 2024-03-04 | 라이엘 이뮤노파마, 인크. | Nr4a3-결핍 면역 세포 및 이의 용도 |
| KR20240042484A (ko) * | 2021-08-02 | 2024-04-02 | 아마타 파마슈티컬스, 인크. | 향상된 항균 활성을 갖는 박테리오파지 |
| CN113755451B (zh) * | 2021-09-03 | 2023-06-06 | 广西大学 | 一株大肠杆菌噬菌体gn6及其应用 |
| EP4248987A1 (en) * | 2022-03-21 | 2023-09-27 | Nomad Bioscience GmbH | Chimeric bacteriocins and method for the control of pseudomonas |
| KR20250027283A (ko) | 2022-05-19 | 2025-02-25 | 라이엘 이뮤노파마, 인크. | nr4a3을 표적하는 폴리뉴클레오타이드 및 이의 용도 |
| WO2024064952A1 (en) | 2022-09-23 | 2024-03-28 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells overexpressing c-jun |
| WO2024064958A1 (en) | 2022-09-23 | 2024-03-28 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells |
| WO2024077174A1 (en) | 2022-10-05 | 2024-04-11 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells |
| WO2025208072A1 (en) * | 2024-03-29 | 2025-10-02 | The General Hospital Corporation | Methods and materials for treating disorders related to bacterial infections |
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| US5877279A (en) * | 1994-10-13 | 1999-03-02 | Nanoframes, Llc | Materials for the production of nanometer structures and use thereof |
| WO1999023107A1 (en) * | 1997-10-31 | 1999-05-14 | Maxygen, Incorporated | Modification of virus tropism and host range by viral genome shuffling |
| GB9803351D0 (en) * | 1998-02-17 | 1998-04-15 | Oxford Biomedica Ltd | Anti-viral vectors |
| GB9809414D0 (en) | 1998-05-02 | 1998-07-01 | Scottish Crop Research Inst | Method |
| US7019122B1 (en) | 1998-10-30 | 2006-03-28 | Janssen Pharmaceutica N.V. | Unusual retrotransposon from the yeast Candida albicans |
| ES2252263T3 (es) * | 2000-07-25 | 2006-05-16 | The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services | Bacteriofago que tiene una gama de hospedadores multiple. |
| WO2006021944A1 (en) | 2004-08-12 | 2006-03-02 | Leanway Automatic Areanas Ltd. | Enhanced database structure configuration |
| US8182804B1 (en) * | 2004-09-13 | 2012-05-22 | Trustees Of Boston University | Engineered enzymatically active bacteriophages and methods of uses thereof |
| EP1828390B1 (en) * | 2004-12-15 | 2012-06-13 | The University Of North Carolina At Chapel Hill | Chimeric vectors |
| US20070004041A1 (en) | 2005-06-30 | 2007-01-04 | Codon Devices, Inc. | Heirarchical assembly methods for genome engineering |
| DE602006015701D1 (de) | 2005-12-29 | 2010-09-02 | Abl Biotechnologies Ltd | Neuer schizochytrium-limacinum-stamm, der sich für die produktion von lipiden und extrazellulären polysacchariden eignet, sowie verfahren hierfür |
| US8216844B2 (en) | 2006-08-29 | 2012-07-10 | Danisco Us Inc. | Compositions and methods for improved protein production |
| EP2147113A1 (en) | 2007-05-23 | 2010-01-27 | Cognis IP Management GmbH | Efficient astaxanthin production strains derived from haematococcus pluvialis |
| GB0715416D0 (en) * | 2007-08-07 | 2007-09-19 | Phico Therapeutics Ltd | Modified bacteriophage |
| CA2711841A1 (en) | 2008-01-10 | 2009-09-03 | Trustees Of Boston University | Engineered bacteriophages as adjuvants for antimicrobial agents and compositions and methods of use thereof |
| AU2009214435C1 (en) | 2008-02-15 | 2014-07-17 | Synthetic Genomics, Inc. | Methods for in vitro joining and combinatorial assembly of nucleic acid molecules |
| US8207363B2 (en) | 2009-03-19 | 2012-06-26 | Martek Biosciences Corporation | Thraustochytrids, fatty acid compositions, and methods of making and uses thereof |
| CN101928670B (zh) | 2009-09-24 | 2012-02-22 | 上海天伟生物制药有限公司 | 一种抗生素的高产菌株及其制备方法和用途 |
| US8524220B1 (en) | 2010-02-09 | 2013-09-03 | David Gordon Bermudes | Protease inhibitor: protease sensitivity expression system composition and methods improving the therapeutic activity and specificity of proteins delivered by bacteria |
| CA3048783C (en) * | 2010-09-17 | 2022-05-24 | Tecnifar-Industria Tecnica Farmaceutica, S.A. | Antibacterial phage, phage peptides and methods of use thereof |
| SG10201606285YA (en) * | 2012-02-01 | 2016-09-29 | Synthetic Genomics Inc | Materials and methods for the synthesis of error-minimized nucleic acid molecules |
| EP3241902B1 (en) | 2012-05-25 | 2018-02-28 | The Regents of The University of California | Methods and compositions for rna-directed target dna modification and for rna-directed modulation of transcription |
| US8697359B1 (en) | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
| US9234213B2 (en) | 2013-03-15 | 2016-01-12 | System Biosciences, Llc | Compositions and methods directed to CRISPR/Cas genomic engineering systems |
| WO2015035168A1 (en) * | 2013-09-05 | 2015-03-12 | Massachusetts Institute Of Technolgy | Tuning bacteriophage host range |
| CN107207614B (zh) * | 2014-10-09 | 2022-01-11 | 利普泰克有限公司 | 嵌合蛋白 |
| EP3234136B1 (en) | 2014-12-16 | 2024-08-21 | C3J Therapeutics, Inc. | Compositions of and methods for in vitro viral genome engineering |
-
2015
- 2015-12-15 EP EP15870907.1A patent/EP3234136B1/en active Active
- 2015-12-15 JP JP2017532046A patent/JP6842417B2/ja active Active
- 2015-12-15 ES ES15870907T patent/ES2991077T3/es active Active
- 2015-12-15 EP EP24195039.3A patent/EP4484556A3/en active Pending
- 2015-12-15 CN CN202110495059.2A patent/CN113215115B/zh active Active
- 2015-12-15 WO PCT/US2015/065891 patent/WO2016100389A1/en not_active Ceased
- 2015-12-15 CA CA3254091A patent/CA3254091A1/en active Pending
- 2015-12-15 CN CN201580076597.0A patent/CN107278227B/zh active Active
- 2015-12-15 AU AU2015362618A patent/AU2015362618B2/en active Active
- 2015-12-15 CA CA2971205A patent/CA2971205A1/en active Pending
- 2015-12-15 US US14/970,458 patent/US10221398B2/en active Active
- 2015-12-15 EA EA201791343A patent/EA038595B1/ru unknown
-
2019
- 2019-01-11 US US16/246,381 patent/US10711253B2/en active Active
- 2019-04-03 US US16/374,646 patent/US10837004B2/en active Active
-
2020
- 2020-11-16 US US17/099,633 patent/US11913032B2/en active Active
-
2021
- 2021-02-19 JP JP2021024982A patent/JP7133671B2/ja active Active
-
2022
- 2022-04-26 AU AU2022202713A patent/AU2022202713B2/en active Active
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