JP2017536089A5 - - Google Patents
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- JP2017536089A5 JP2017536089A5 JP2017517081A JP2017517081A JP2017536089A5 JP 2017536089 A5 JP2017536089 A5 JP 2017536089A5 JP 2017517081 A JP2017517081 A JP 2017517081A JP 2017517081 A JP2017517081 A JP 2017517081A JP 2017536089 A5 JP2017536089 A5 JP 2017536089A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- binding
- antibody
- binding molecule
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14003383 | 2014-09-30 | ||
| EP14003383.8 | 2014-09-30 | ||
| PCT/EP2015/072279 WO2016050702A1 (en) | 2014-09-30 | 2015-09-28 | Binding molecules, especially antibodies, binding to l1cam (cd171) |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017536089A JP2017536089A (ja) | 2017-12-07 |
| JP2017536089A5 true JP2017536089A5 (https=) | 2020-01-30 |
| JP6875275B2 JP6875275B2 (ja) | 2021-05-19 |
Family
ID=51743255
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017517081A Active JP6875275B2 (ja) | 2014-09-30 | 2015-09-28 | Ｌ１ｃａｍ（ｃｄ１７）と結合する抗体などの結合分子 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10400037B2 (https=) |
| EP (1) | EP3200822B1 (https=) |
| JP (1) | JP6875275B2 (https=) |
| KR (1) | KR102554634B1 (https=) |
| CN (1) | CN107108741B (https=) |
| AU (1) | AU2015327064B2 (https=) |
| CL (1) | CL2017000756A1 (https=) |
| DK (1) | DK3200822T3 (https=) |
| ES (1) | ES2881575T3 (https=) |
| MX (1) | MX388698B (https=) |
| PL (1) | PL3200822T3 (https=) |
| RU (1) | RU2754684C2 (https=) |
| SI (1) | SI3200822T1 (https=) |
| WO (1) | WO2016050702A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107118271B (zh) * | 2016-12-21 | 2021-01-22 | 四川百利药业有限责任公司 | 可用于富集人l1cam蛋白的抗原多肽和单克隆抗体 |
| JP2021518748A (ja) * | 2018-02-23 | 2021-08-05 | アールイーエムディー バイオセラピューティクス，インコーポレイテッドＲＥＭＤ Ｂｉｏｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ | カルシトニン遺伝子関連ペプチド（ｃｇｒｐ）アンタゴニスト抗体 |
| WO2020003210A1 (en) | 2018-06-29 | 2020-01-02 | Kangwon National University University-Industry Cooperation Foundation | Anti-l1cam antibodies and uses thereof |
| US12036242B2 (en) | 2018-07-05 | 2024-07-16 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | CAR T cells that target B-cell antigens |
| CN108949997A (zh) * | 2018-08-24 | 2018-12-07 | 南京求臻基因科技有限公司 | 一种肺癌检测标志物及诊断试剂盒 |
| CN112239505B (zh) * | 2020-10-13 | 2022-05-20 | 上海良润生物医药科技有限公司 | 重组抗cd171八价抗体及神经来源外泌体的捕获方法 |
| CN112010980B (zh) * | 2020-10-13 | 2021-01-22 | 上海良润生物医药科技有限公司 | 重组抗cd171双特异抗体及神经来源外泌体的捕获方法 |
| KR20240091226A (ko) * | 2021-11-03 | 2024-06-21 | 큐론 바이오파마슈티칼 (상하이) 컴퍼니, 리미티드 | 신규 항 l1cam 항체 |
| CN114933636B (zh) * | 2022-06-24 | 2023-05-09 | 浙江省人民医院 | 靶向l1cam的多肽及其应用 |
| CA3262904A1 (en) | 2022-09-21 | 2024-03-28 | Elthera Ag | NEW BINDING MOLECULES THAT BIND TO L1CAM |
| TW202417057A (zh) * | 2022-10-26 | 2024-05-01 | 大陸商同潤生物醫藥(上海)有限公司 | 人源化的l1cam抗體藥物偶聯物 |
| CN121941710A (zh) | 2023-09-27 | 2026-04-28 | 艾尔瑟拉股份有限公司 | 用于治疗血液恶性肿瘤疾病的l1cam结合分子 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| EP0436597B1 (en) | 1988-09-02 | 1997-04-02 | Protein Engineering Corporation | Generation and selection of recombinant varied binding proteins |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| ES2091824T3 (es) | 1989-04-21 | 1996-11-16 | Us Health | Proteina recombinante de fusion toxina anticuerpo. |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| DK0585287T3 (da) | 1990-07-10 | 2000-04-17 | Cambridge Antibody Tech | Fremgangsmåde til fremstilling af specifikke bindingsparelementer |
| CA2095633C (en) | 1990-12-03 | 2003-02-04 | Lisa J. Garrard | Enrichment method for variant proteins with altered binding properties |
| EP1820858B1 (en) | 1991-03-01 | 2009-08-12 | Dyax Corporation | Chimeric protein comprising micro-protein having two or more disulfide bonds and embodiments thereof |
| ATE414768T1 (de) | 1991-04-10 | 2008-12-15 | Scripps Research Inst | Bibliotheken heterodimerer rezeptoren mittels phagemiden |
| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
| AU4953693A (en) | 1992-08-25 | 1994-03-15 | Medac Gesellschaft Fur Klinische Spezialpraparate Mbh | Antibody/radioisotope conjugate for tumor diagnosis and/or therapy |
| US5837283A (en) | 1997-03-12 | 1998-11-17 | The Regents Of The University Of California | Cationic lipid compositions targeting angiogenic endothelial cells |
| GB0209893D0 (en) | 2002-04-30 | 2002-06-05 | Molmed Spa | Conjugate |
| KR100470535B1 (ko) | 2002-06-27 | 2005-02-22 | 재단법인서울대학교산학협력재단 | 유피에이 항체 부착 이뮤노리포좀 |
| US20040202666A1 (en) | 2003-01-24 | 2004-10-14 | Immunomedics, Inc. | Anti-cancer anthracycline drug-antibody conjugates |
| EP1928912A4 (en) | 2005-09-07 | 2010-02-24 | Medimmune Inc | EPH ANTI-RECEPTOR ANTIBODIES CONJUGATED TO TOXINS |
| BRPI0717638A2 (pt) * | 2006-10-27 | 2013-11-12 | Genentech Inc | Anticorpors e imunoconjugados e usos para os mesmos |
| LT2631248T (lt) * | 2007-06-15 | 2018-04-25 | Medigene Ag | Navikų gydymas, naudojant specifinį anti-l1 antikūną |
| AU2008201871A1 (en) * | 2008-04-16 | 2009-11-26 | Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts | Inhibition of angiogenesis and tumor metastasis |
| CN105188749B (zh) * | 2012-12-21 | 2017-12-19 | 西雅图基因公司 | 抗ntb‑a抗体及相关组合物和方法 |
-
2015
- 2015-09-28 EP EP15770889.2A patent/EP3200822B1/en active Active
- 2015-09-28 JP JP2017517081A patent/JP6875275B2/ja active Active
- 2015-09-28 DK DK15770889.2T patent/DK3200822T3/da active
- 2015-09-28 PL PL15770889T patent/PL3200822T3/pl unknown
- 2015-09-28 AU AU2015327064A patent/AU2015327064B2/en active Active
- 2015-09-28 KR KR1020177011592A patent/KR102554634B1/ko active Active
- 2015-09-28 CN CN201580064942.9A patent/CN107108741B/zh active Active
- 2015-09-28 US US15/515,722 patent/US10400037B2/en active Active
- 2015-09-28 MX MX2017004117A patent/MX388698B/es unknown
- 2015-09-28 WO PCT/EP2015/072279 patent/WO2016050702A1/en not_active Ceased
- 2015-09-28 ES ES15770889T patent/ES2881575T3/es active Active
- 2015-09-28 RU RU2017114968A patent/RU2754684C2/ru active
- 2015-09-28 SI SI201531649T patent/SI3200822T1/sl unknown
-
2017
- 2017-03-29 CL CL2017000756A patent/CL2017000756A1/es unknown
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