JP2017534638A5 - - Google Patents
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- JP2017534638A5 JP2017534638A5 JP2017524049A JP2017524049A JP2017534638A5 JP 2017534638 A5 JP2017534638 A5 JP 2017534638A5 JP 2017524049 A JP2017524049 A JP 2017524049A JP 2017524049 A JP2017524049 A JP 2017524049A JP 2017534638 A5 JP2017534638 A5 JP 2017534638A5
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- Prior art keywords
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- 241000124008 Mammalia Species 0.000 claims description 37
- 206010064930 age-related macular degeneration Diseases 0.000 claims description 28
- 238000000034 method Methods 0.000 claims description 25
- 201000006165 Kuhnt-Junius degeneration Diseases 0.000 claims description 23
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims description 23
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims description 23
- 208000000208 Wet Macular Degeneration Diseases 0.000 claims description 23
- 239000005557 antagonist Substances 0.000 claims description 23
- 230000009266 disease activity Effects 0.000 claims description 20
- 208000031513 cyst Diseases 0.000 claims description 14
- 239000012530 fluid Substances 0.000 claims description 14
- 230000004304 visual acuity Effects 0.000 claims description 14
- 210000001525 retina Anatomy 0.000 claims description 12
- 206010011732 Cyst Diseases 0.000 claims description 10
- 238000002347 injection Methods 0.000 claims description 4
- 239000007924 injection Substances 0.000 claims description 4
- 238000011156 evaluation Methods 0.000 claims description 2
- 230000000007 visual effect Effects 0.000 claims description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 29
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000006467 substitution reaction Methods 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462076770P | 2014-11-07 | 2014-11-07 | |
| US62/076,770 | 2014-11-07 | ||
| US201462088061P | 2014-12-05 | 2014-12-05 | |
| US62/088,061 | 2014-12-05 | ||
| PCT/US2015/059575 WO2016073918A1 (en) | 2014-11-07 | 2015-11-06 | Methods for treating ocular diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020138531A Division JP2020193212A (ja) | 2014-11-07 | 2020-08-19 | 眼疾患を処置する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017534638A JP2017534638A (ja) | 2017-11-24 |
| JP2017534638A5 true JP2017534638A5 (OSRAM) | 2018-12-06 |
| JP6753848B2 JP6753848B2 (ja) | 2020-09-09 |
Family
ID=54697654
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017523878A Active JP6667519B2 (ja) | 2014-11-07 | 2015-11-06 | 高濃度の抗ｖｅｇｆ抗体を含有する安定状態のタンパク質溶液製剤 |
| JP2017524049A Active JP6753848B2 (ja) | 2014-11-07 | 2015-11-06 | 眼疾患を処置する方法 |
| JP2020000823A Active JP7080263B2 (ja) | 2014-11-07 | 2020-01-07 | 高濃度の抗ｖｅｇｆ抗体を含有する安定状態のタンパク質溶液製剤 |
| JP2020138531A Withdrawn JP2020193212A (ja) | 2014-11-07 | 2020-08-19 | 眼疾患を処置する方法 |
| JP2022119423A Pending JP2022141923A (ja) | 2014-11-07 | 2022-07-27 | 眼疾患を処置する方法 |
| JP2024170733A Pending JP2025004075A (ja) | 2014-11-07 | 2024-09-30 | 眼疾患を処置する方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017523878A Active JP6667519B2 (ja) | 2014-11-07 | 2015-11-06 | 高濃度の抗ｖｅｇｆ抗体を含有する安定状態のタンパク質溶液製剤 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020000823A Active JP7080263B2 (ja) | 2014-11-07 | 2020-01-07 | 高濃度の抗ｖｅｇｆ抗体を含有する安定状態のタンパク質溶液製剤 |
| JP2020138531A Withdrawn JP2020193212A (ja) | 2014-11-07 | 2020-08-19 | 眼疾患を処置する方法 |
| JP2022119423A Pending JP2022141923A (ja) | 2014-11-07 | 2022-07-27 | 眼疾患を処置する方法 |
| JP2024170733A Pending JP2025004075A (ja) | 2014-11-07 | 2024-09-30 | 眼疾患を処置する方法 |
Country Status (24)
| Country | Link |
|---|---|
| US (5) | US10035850B2 (OSRAM) |
| EP (2) | EP3215123A1 (OSRAM) |
| JP (6) | JP6667519B2 (OSRAM) |
| KR (4) | KR20240161204A (OSRAM) |
| CN (4) | CN114081951A (OSRAM) |
| AU (6) | AU2015342818B2 (OSRAM) |
| BR (2) | BR112017008093A2 (OSRAM) |
| CA (2) | CA2966646A1 (OSRAM) |
| CL (2) | CL2017001117A1 (OSRAM) |
| CO (1) | CO2017004596A2 (OSRAM) |
| EA (1) | EA201790989A1 (OSRAM) |
| EC (1) | ECSP17034829A (OSRAM) |
| GT (1) | GT201700096A (OSRAM) |
| IL (5) | IL251642B (OSRAM) |
| MX (3) | MX383808B (OSRAM) |
| MY (2) | MY183807A (OSRAM) |
| NZ (1) | NZ730821A (OSRAM) |
| PE (1) | PE20170780A1 (OSRAM) |
| PH (3) | PH12021550147A1 (OSRAM) |
| RU (1) | RU2722643C2 (OSRAM) |
| SG (3) | SG10201913565RA (OSRAM) |
| TN (1) | TN2017000128A1 (OSRAM) |
| TW (4) | TWI705827B (OSRAM) |
| WO (2) | WO2016073915A1 (OSRAM) |
Families Citing this family (58)
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| EP3252079B8 (en) | 2006-04-07 | 2020-09-09 | Aerpio Therapeutics LLC | Antibodies that bind human protein tyrosine phosphatase beta (hptp-beta) and uses thereof |
| US7622593B2 (en) | 2006-06-27 | 2009-11-24 | The Procter & Gamble Company | Human protein tyrosine phosphatase inhibitors and methods of use |
| MX345039B (es) | 2008-06-25 | 2017-01-16 | Esbatech Alcon Biomed Res Unit | Anticuerpos estables y solubles que inhiben el tnfa. |
| KR101834797B1 (ko) | 2008-06-25 | 2018-03-07 | 에스바테크 - 어 노바티스 컴파니 엘엘씨 | 보편적 항체 프레임워크를 사용한 래빗 항체의 인간화 |
| PL2451279T3 (pl) | 2009-07-06 | 2019-09-30 | Aerpio Therapeutics, Inc. | Pochodne benzosulfonamidowe, ich kompozycje i ich zastosowanie w zapobieganiu przerzutom komórek nowotworowych |
| MX385629B (es) | 2011-01-13 | 2025-03-18 | Regeneron Pharma | Uso de un antagonista de factor de crecimiento endotelial vascular para tratar trastornos oculares angiogenicos. |
| AU2012323856B2 (en) | 2011-10-13 | 2017-05-25 | EyePoint Pharmaceuticals, Inc. | Methods for treating Vascular Leak Syndrome and cancer |
| US20150050277A1 (en) | 2013-03-15 | 2015-02-19 | Aerpio Therapeutics Inc. | Compositions and methods for treating ocular diseases |
| US9994560B2 (en) | 2014-03-14 | 2018-06-12 | Aerpio Therapeutics, Inc. | HPTP-β inhibitors |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| TWI705827B (zh) | 2014-11-07 | 2020-10-01 | 瑞士商諾華公司 | 治療眼部疾病之方法 |
| US10464999B2 (en) | 2015-01-28 | 2019-11-05 | Prothena Biosciences Limited | Anti-transthyretin antibodies |
| US10633433B2 (en) | 2015-01-28 | 2020-04-28 | Prothena Biosciences Limited | Anti-transthyretin antibodies |
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| WO2018063963A1 (en) | 2016-09-28 | 2018-04-05 | Board Of Regents, The University Of Texas System | Antibody and protein therapeutic formulations and uses thereof |
| BR112019010064A2 (pt) | 2016-11-18 | 2019-10-01 | Astellas Pharma Inc | novo fragmento fab do anticorpo muc1 anti-humano |
| MX2019011272A (es) | 2017-03-22 | 2019-10-24 | Novartis Ag | Composiciones y metodos para inmunooncologia. |
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| WO2018195912A1 (zh) * | 2017-04-28 | 2018-11-01 | 苏州思坦维生物技术股份有限公司 | 一种眼用药物组合物及其用途 |
| TWI795415B (zh) | 2017-07-07 | 2023-03-11 | 日商安斯泰來製藥股份有限公司 | 新穎的抗人類ＣＥＡＣＡＭ５抗體Ｆａｂ片段 |
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| JP7292569B2 (ja) | 2017-10-06 | 2023-06-19 | ノボ ノルディスク エー／エス | トランスサイレチンを検出する方法 |
| AU2018345806A1 (en) | 2017-10-06 | 2020-03-12 | Novo Nordisk A/S | Anti-transthyretin antibodies |
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| HUE059827T2 (hu) | 2017-11-30 | 2023-01-28 | Regeneron Pharma | VEGF-antagonista alkalmazása angiogén szembetegségek kezelésére |
| MX2020007527A (es) * | 2018-02-06 | 2020-09-09 | Hoffmann La Roche | Tratamiento de enfermedades oftalmologicas. |
| BR112020017872A2 (pt) | 2018-03-02 | 2020-12-22 | Kodiak Sciences Inc. | Anticorpos de il-6 e construtos de fusão e conjugados dos mesmos |
| EP3765083A1 (en) * | 2018-03-16 | 2021-01-20 | Novartis Ag | Methods for treating ocular diseases |
| CA3094934A1 (en) * | 2018-03-23 | 2019-09-26 | AbbVie Deutschland GmbH & Co. KG | Stable aqueous anti-tau antibody formulations |
| EP3775267A4 (en) * | 2018-04-10 | 2022-05-18 | Askgene Pharma, Inc. | NOVEL ANGIOPOIETIN-2, VEGF DUAL ANTAGONISTS |
| NZ770284A (en) | 2018-05-10 | 2025-11-28 | Regeneron Pharma | High concentration vegf receptor fusion protein containing formulations |
| BR112020023420A8 (pt) | 2018-05-17 | 2022-07-05 | Astellas Pharma Inc | Complexo tendo fragmento fab de anticorpo anti-muc1 humano, peptídeo ligador e/ou ligante |
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| TW202532428A (zh) | 2019-04-26 | 2025-08-16 | 美商愛德維仁生物科技公司 | 用於玻璃體內遞送之變異體aav蛋白殼 |
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| WO2021034727A1 (en) | 2019-08-16 | 2021-02-25 | Applied Molecular Transport Inc. | Compositions, formulations, and interleukin production and purification |
| WO2021072265A1 (en) * | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| CN111217834B (zh) * | 2020-02-21 | 2021-10-26 | 维眸生物科技（上海）有限公司 | Rock激酶抑制剂的硝基氧衍生物 |
| BR112022015627A2 (pt) * | 2020-03-04 | 2022-09-27 | Shanghai Henlius Biotech Inc | Formulação farmacêutica que compreende bevacizumabe |
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-
2015
- 2015-10-26 TW TW104135104A patent/TWI705827B/zh active
- 2015-10-26 TW TW110133255A patent/TWI806150B/zh active
- 2015-10-26 TW TW109132401A patent/TWI761959B/zh active
- 2015-10-26 TW TW104135105A patent/TWI738632B/zh active
- 2015-11-06 EA EA201790989A patent/EA201790989A1/ru unknown
- 2015-11-06 PE PE2017000812A patent/PE20170780A1/es unknown
- 2015-11-06 JP JP2017523878A patent/JP6667519B2/ja active Active
- 2015-11-06 WO PCT/US2015/059571 patent/WO2016073915A1/en not_active Ceased
- 2015-11-06 MY MYPI2017701217A patent/MY183807A/en unknown
- 2015-11-06 AU AU2015342818A patent/AU2015342818B2/en active Active
- 2015-11-06 TN TN2017000128A patent/TN2017000128A1/en unknown
- 2015-11-06 RU RU2017119647A patent/RU2722643C2/ru active
- 2015-11-06 KR KR1020247035792A patent/KR20240161204A/ko not_active Ceased
- 2015-11-06 CA CA2966646A patent/CA2966646A1/en active Pending
- 2015-11-06 CN CN202111376360.8A patent/CN114081951A/zh active Pending
- 2015-11-06 KR KR1020177012256A patent/KR20170082526A/ko not_active Ceased
- 2015-11-06 CN CN202511153148.3A patent/CN120938921A/zh active Pending
- 2015-11-06 PH PH1/2021/550147A patent/PH12021550147A1/en unknown
- 2015-11-06 EP EP15807721.4A patent/EP3215123A1/en active Pending
- 2015-11-06 EP EP15798609.2A patent/EP3215122B1/en active Active
- 2015-11-06 BR BR112017008093-1A patent/BR112017008093A2/pt not_active Application Discontinuation
- 2015-11-06 MX MX2017005874A patent/MX383808B/es unknown
- 2015-11-06 CN CN201580060665.4A patent/CN106999581A/zh active Pending
- 2015-11-06 CN CN201580060416.5A patent/CN107635580A/zh active Pending
- 2015-11-06 BR BR112017008660A patent/BR112017008660A2/pt not_active Application Discontinuation
- 2015-11-06 SG SG10201913565RA patent/SG10201913565RA/en unknown
- 2015-11-06 WO PCT/US2015/059575 patent/WO2016073918A1/en not_active Ceased
- 2015-11-06 NZ NZ73082115A patent/NZ730821A/en unknown
- 2015-11-06 SG SG11201702954XA patent/SG11201702954XA/en unknown
- 2015-11-06 JP JP2017524049A patent/JP6753848B2/ja active Active
- 2015-11-06 US US14/934,731 patent/US10035850B2/en active Active
- 2015-11-06 US US14/934,666 patent/US10689438B2/en active Active
- 2015-11-06 AU AU2015342815A patent/AU2015342815B2/en active Active
- 2015-11-06 SG SG11201702909QA patent/SG11201702909QA/en unknown
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