JP2017534056A5 - - Google Patents
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- Publication number
- JP2017534056A5 JP2017534056A5 JP2017523343A JP2017523343A JP2017534056A5 JP 2017534056 A5 JP2017534056 A5 JP 2017534056A5 JP 2017523343 A JP2017523343 A JP 2017523343A JP 2017523343 A JP2017523343 A JP 2017523343A JP 2017534056 A5 JP2017534056 A5 JP 2017534056A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- seq
- hcv
- ns3h capture
- peptides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 39
- 102000004196 processed proteins & peptides Human genes 0.000 claims 17
- 241000711549 Hepacivirus C Species 0.000 claims 12
- 125000003275 alpha amino acid group Chemical group 0.000 claims 12
- 239000012472 biological sample Substances 0.000 claims 12
- 238000000034 method Methods 0.000 claims 9
- 101800001838 Serine protease/helicase NS3 Proteins 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 5
- 239000000523 sample Substances 0.000 claims 5
- 108700039791 Hepatitis C virus nucleocapsid Proteins 0.000 claims 3
- 239000012634 fragment Substances 0.000 claims 3
- 239000002245 particle Substances 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 1
- 238000010187 selection method Methods 0.000 claims 1
- 238000005406 washing Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462072266P | 2014-10-29 | 2014-10-29 | |
| US62/072,266 | 2014-10-29 | ||
| PCT/US2015/057845 WO2016069762A2 (en) | 2014-10-29 | 2015-10-28 | Subject anti-hcv antibody detection assays employing ns3 capture peptides |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021000346A Division JP2021063827A (ja) | 2014-10-29 | 2021-01-05 | Ｎｓ３捕捉ペプチドを使用して対象の抗ｈｃｖ抗体を検出するアッセイ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017534056A JP2017534056A (ja) | 2017-11-16 |
| JP2017534056A5 true JP2017534056A5 (https=) | 2018-11-22 |
| JP6821562B2 JP6821562B2 (ja) | 2021-01-27 |
Family
ID=54479000
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017523343A Active JP6821562B2 (ja) | 2014-10-29 | 2015-10-28 | Ｎｓ３捕捉ペプチドを使用して対象の抗ｈｃｖ抗体を検出するアッセイ |
| JP2021000346A Pending JP2021063827A (ja) | 2014-10-29 | 2021-01-05 | Ｎｓ３捕捉ペプチドを使用して対象の抗ｈｃｖ抗体を検出するアッセイ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021000346A Pending JP2021063827A (ja) | 2014-10-29 | 2021-01-05 | Ｎｓ３捕捉ペプチドを使用して対象の抗ｈｃｖ抗体を検出するアッセイ |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US10088483B2 (https=) |
| EP (1) | EP3213083B1 (https=) |
| JP (2) | JP6821562B2 (https=) |
| KR (1) | KR102441636B1 (https=) |
| CN (1) | CN107110868B (https=) |
| ES (1) | ES2828713T3 (https=) |
| WO (1) | WO2016069762A2 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2828713T3 (es) | 2014-10-29 | 2021-05-27 | Abbott Lab | Ensayos de detección de anticuerpos anti-VHC objeto usando péptidos de captura NS3 |
| CN110996986B (zh) * | 2017-07-27 | 2024-07-19 | 豪夫迈·罗氏有限公司 | Hcv抗原的多表位融合蛋白及其用途 |
| CN112341527B (zh) * | 2020-09-16 | 2021-08-31 | 菲鹏生物股份有限公司 | Hcv重组抗原及应用 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3750503T2 (de) | 1986-10-22 | 1995-02-09 | Abbott Lab | Chemilumineszierende Acridinium- und Phenantridiniumsalze. |
| US5006309A (en) | 1988-04-22 | 1991-04-09 | Abbott Laboratories | Immunoassay device with liquid transfer between wells by washing |
| US5089424A (en) | 1988-06-14 | 1992-02-18 | Abbott Laboratories | Method and apparatus for heterogeneous chemiluminescence assay |
| US5241070A (en) | 1988-09-26 | 1993-08-31 | Ciba Corning Diagnostics Corp. | Nucleophilic polysubstituted aryl acridinium esters and uses thereof |
| SE462454B (sv) | 1988-11-10 | 1990-06-25 | Pharmacia Ab | Maetyta foer anvaendning i biosensorer |
| US5063081A (en) | 1988-11-14 | 1991-11-05 | I-Stat Corporation | Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor |
| HU217025B (hu) * | 1990-04-04 | 1999-11-29 | Chiron Corp. | Hepatitis C vírus-(HCV) antigénkészítmények az anti-HCV-antitestek kimutatására immunoassay-kben |
| US6194140B1 (en) * | 1990-04-04 | 2001-02-27 | Chiron Corporation | HCV NS3 protein fragments having helicase activity and improved solubility |
| US5135785A (en) | 1990-08-13 | 1992-08-04 | Colgate-Palmolive Company | Pouch containers and films therefor |
| CA2048302A1 (en) | 1990-08-15 | 1992-02-16 | Victoria P. Meucci | Solubilization reagent for biological test samples |
| US5135875A (en) | 1990-08-15 | 1992-08-04 | Abbott Laboratories | Protein precipitation reagent |
| CA2069530A1 (en) | 1991-06-03 | 1992-12-04 | Cass J. Grandone | Reagent pack for immunoassays |
| JP3327551B2 (ja) | 1992-03-30 | 2002-09-24 | アボツト・ラボラトリーズ | 流体試料中のチロキシンを検出・定量するための試薬および方法 |
| US5352803A (en) | 1992-03-30 | 1994-10-04 | Abbott Laboratories | 5(6)-methyl substituted fluorescein derivatives |
| DE4428705A1 (de) * | 1994-08-12 | 1996-02-15 | Boehringer Mannheim Gmbh | Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus |
| NZ516848A (en) | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
| CA2323638A1 (en) | 1998-04-03 | 1999-10-14 | Phylos, Inc. | Addressable protein arrays |
| DK1071955T4 (da) * | 1998-04-17 | 2009-06-15 | Innogenetics Nv | Forbedrede immundiagnostiske assays, som anvender reduktionsmidler |
| US6406921B1 (en) | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
| WO2000056934A1 (en) | 1999-03-24 | 2000-09-28 | Packard Bioscience Company | Continuous porous matrix arrays |
| FR2825093B1 (fr) * | 2001-05-28 | 2003-07-18 | Bio Merieux | Polypeptide reagissant avecles anticorps de patients infectes par vhc et utilisations |
| US7101683B2 (en) * | 2001-06-26 | 2006-09-05 | Abbott Laboratories | Methods for the simultaneous detection of HCV antigens and HCV antibodies |
| US7419821B2 (en) | 2002-03-05 | 2008-09-02 | I-Stat Corporation | Apparatus and methods for analyte measurement and immunoassay |
| US20040018577A1 (en) | 2002-07-29 | 2004-01-29 | Emerson Campbell John Lewis | Multiple hybrid immunoassay |
| US20040152070A1 (en) * | 2003-02-04 | 2004-08-05 | Shah Dinesh O. | Method of detection of HCV antibodies in combination assay or sole antibody assay |
| US20050014136A1 (en) * | 2003-05-28 | 2005-01-20 | Innogenetics N.V. | Modified HCV NS5 |
| US7682833B2 (en) | 2003-09-10 | 2010-03-23 | Abbott Point Of Care Inc. | Immunoassay device with improved sample closure |
| US7723099B2 (en) | 2003-09-10 | 2010-05-25 | Abbott Point Of Care Inc. | Immunoassay device with immuno-reference electrode |
| US7883855B2 (en) | 2006-07-21 | 2011-02-08 | Abbott Laboratories | Immunosuppressant drug extraction reagent for immunoassays |
| US8865398B2 (en) * | 2006-09-01 | 2014-10-21 | Abbott Laboratories | Combination hepatitis C virus antigen and antibody detection method |
| US7858752B2 (en) | 2006-12-05 | 2010-12-28 | Abbott Laboratories | Recombinant antibodies against hepatitis C virus and methods of obtaining and using same |
| US7906293B2 (en) | 2007-04-09 | 2011-03-15 | Abbott Laboratories | Acridinium phenyl esters useful in the analysis of biological |
| CN101477126A (zh) * | 2008-09-24 | 2009-07-08 | 湖南景达生物工程有限公司 | 一种丙型肝炎病毒抗原抗体联合检测的方法 |
| WO2012006500A2 (en) | 2010-07-08 | 2012-01-12 | Abbott Laboratories | Monoclonal antibodies against hepatitis c virus core protein |
| JP5828728B2 (ja) * | 2011-09-28 | 2015-12-09 | 株式会社日立ハイテクノロジーズ | 自動分析装置 |
| JP2016512241A (ja) * | 2013-03-14 | 2016-04-25 | アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ | 改良された抗体検出のためのｈｃｖｎｓ３組換え抗原およびこの突然変異体 |
| MX362075B (es) | 2013-03-14 | 2019-01-07 | Abbott Lab | Ensayo de combinación de antígeno-anticuerpo del virus de la hepatitis c (vhc) y métodos y composiciones para usarlo. |
| WO2014143343A1 (en) | 2013-03-14 | 2014-09-18 | Abbott Laboratories | Hcv core lipid binding domain monoclonal antibodies |
| CN103792354B (zh) * | 2014-01-28 | 2015-11-25 | 中国医学科学院基础医学研究所 | 一种检测丙型肝炎病毒抗体的微流控纸基芯片及其制备方法 |
| ES2828713T3 (es) | 2014-10-29 | 2021-05-27 | Abbott Lab | Ensayos de detección de anticuerpos anti-VHC objeto usando péptidos de captura NS3 |
-
2015
- 2015-10-28 ES ES15791861T patent/ES2828713T3/es active Active
- 2015-10-28 CN CN201580071470.XA patent/CN107110868B/zh active Active
- 2015-10-28 EP EP15791861.6A patent/EP3213083B1/en active Active
- 2015-10-28 WO PCT/US2015/057845 patent/WO2016069762A2/en not_active Ceased
- 2015-10-28 JP JP2017523343A patent/JP6821562B2/ja active Active
- 2015-10-28 KR KR1020177014533A patent/KR102441636B1/ko active Active
- 2015-10-28 US US14/925,778 patent/US10088483B2/en active Active
-
2018
- 2018-09-05 US US16/122,261 patent/US10816551B2/en active Active
-
2020
- 2020-10-15 US US17/071,976 patent/US11340230B2/en active Active
-
2021
- 2021-01-05 JP JP2021000346A patent/JP2021063827A/ja active Pending
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