JP2011522561A5 - - Google Patents
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- Publication number
- JP2011522561A5 JP2011522561A5 JP2011513436A JP2011513436A JP2011522561A5 JP 2011522561 A5 JP2011522561 A5 JP 2011522561A5 JP 2011513436 A JP2011513436 A JP 2011513436A JP 2011513436 A JP2011513436 A JP 2011513436A JP 2011522561 A5 JP2011522561 A5 JP 2011522561A5
- Authority
- JP
- Japan
- Prior art keywords
- synthetic peptide
- recombinant phage
- peptide according
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 26
- 241000712461 unidentified influenza virus Species 0.000 claims description 12
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 11
- 230000004927 fusion Effects 0.000 claims description 10
- 241000700605 Viruses Species 0.000 claims description 7
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims description 5
- 102000012750 Membrane Glycoproteins Human genes 0.000 claims description 3
- 108010090054 Membrane Glycoproteins Proteins 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 208000002979 Influenza in Birds Diseases 0.000 claims 2
- 206010064097 avian influenza Diseases 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 238000003745 diagnosis Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 210000002845 virion Anatomy 0.000 description 3
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 2
- 102000018697 Membrane Proteins Human genes 0.000 description 2
- 108010052285 Membrane Proteins Proteins 0.000 description 2
- 230000000840 anti-viral effect Effects 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- 229940098773 bovine serum albumin Drugs 0.000 description 2
- 125000004122 cyclic group Chemical group 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 101710132601 Capsid protein Proteins 0.000 description 1
- 101710094648 Coat protein Proteins 0.000 description 1
- 108091035707 Consensus sequence Proteins 0.000 description 1
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- 102100021181 Golgi phosphoprotein 3 Human genes 0.000 description 1
- 239000000232 Lipid Bilayer Substances 0.000 description 1
- 101710125418 Major capsid protein Proteins 0.000 description 1
- 101710141454 Nucleoprotein Proteins 0.000 description 1
- 101710083689 Probable capsid protein Proteins 0.000 description 1
- 108010090804 Streptavidin Proteins 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 229940039227 diagnostic agent Drugs 0.000 description 1
- 239000000032 diagnostic agent Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003446 ligand Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000013642 negative control Substances 0.000 description 1
- 238000004091 panning Methods 0.000 description 1
- 238000002823 phage display Methods 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000017610 release of virus from host Effects 0.000 description 1
- 241001515965 unidentified phage Species 0.000 description 1
- 230000007502 viral entry Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI20082061 | 2008-06-12 | ||
| MYPI20082061A MY160435A (en) | 2008-06-12 | 2008-06-12 | A novel antiviral peptide against avian influenza virus h9n2 |
| PCT/MY2009/000071 WO2009151313A1 (en) | 2008-06-12 | 2009-06-10 | A novel antiviral peptide against avian influenza virus h9n2 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011522561A JP2011522561A (ja) | 2011-08-04 |
| JP2011522561A5 true JP2011522561A5 (https=) | 2012-07-19 |
| JP5647111B2 JP5647111B2 (ja) | 2014-12-24 |
Family
ID=41416902
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011513436A Expired - Fee Related JP5647111B2 (ja) | 2008-06-12 | 2009-06-10 | トリインフルエンザウイルスｈ９ｎ２に対する新規な抗ウイルスペプチド |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8883480B2 (https=) |
| EP (1) | EP2300492B1 (https=) |
| JP (1) | JP5647111B2 (https=) |
| DK (1) | DK2300492T3 (https=) |
| MY (1) | MY160435A (https=) |
| WO (1) | WO2009151313A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH12013500204A1 (en) * | 2010-08-03 | 2013-04-01 | Univ Washington Through Its Center For Commercialization | Polypeptides for treating and/or limiting influenza infection |
| CN102830225B (zh) * | 2012-09-24 | 2014-06-04 | 中国动物疫病预防控制中心 | 一种源于禽流感病毒自然弱毒株的血凝素和免疫抗原 |
| MY184269A (en) * | 2015-11-27 | 2021-03-30 | Viramatix Sdn Bhd | Broad-spectrum anti-influenza virus therapeutic peptides |
| US11376306B2 (en) | 2017-05-26 | 2022-07-05 | Viramatix Sdn Bhd | Peptides and uses therefor as antiviral agents |
| US12421626B2 (en) | 2018-06-29 | 2025-09-23 | Fred Hutchinson Cancer Center | Cell-stored barcoded deep mutational scanning libraries and uses of the same |
| CN109628641B (zh) * | 2019-01-07 | 2022-03-01 | 广西壮族自治区兽医研究所 | 用于检测h7以及5个na亚型aiv的引物组合及其应用 |
| CN109487011B (zh) * | 2019-01-07 | 2022-03-01 | 广西壮族自治区兽医研究所 | 用于检测h5、h7和h9以及9个na亚型aiv的引物组合及其应用 |
| CN109487012B (zh) * | 2019-01-07 | 2020-09-22 | 广西壮族自治区兽医研究所 | 用于检测9个na亚型aiv的引物组合及其应用 |
| US11821111B2 (en) | 2019-11-15 | 2023-11-21 | Fred Hutchinson Cancer Center | Barcoded influenza viruses and deep mutational scanning libraries including the same |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| CA2323064C (en) * | 1998-03-17 | 2011-05-31 | Gendaq Limited | Nucleic acid binding proteins |
| EP1167382A1 (en) * | 1999-03-31 | 2002-01-02 | Otsuka Pharmaceutical Co., Ltd. | Influenza virus hemagglutinin-binding peptides |
| EP1441750A4 (en) * | 2001-07-11 | 2006-10-18 | Palatin Technologies Inc | LINEAR AND CYCLIC PEPTIDES SPECIFIC TO THE MELANOCORTIN RECEPTOR |
| US7888121B2 (en) * | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| AU2006279323B2 (en) * | 2005-08-16 | 2013-08-01 | Merck Sharp & Dohme Corp. | Influenza recombinant subunit vaccine |
| EP2003198A2 (en) * | 2006-03-13 | 2008-12-17 | Keio University | Peptide for inhibition of influenza infection, inhibitor of influenza infection, liposome, and prophylactic/therapeutic agent for influenza |
| US8685687B2 (en) * | 2006-07-05 | 2014-04-01 | The Scripps Research Institute | Chimeric zinc finger recombinases optimized for catalysis by directed evolution |
| US8778847B2 (en) * | 2007-06-13 | 2014-07-15 | The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Immunogenic peptides of influenza virus |
| WO2008154813A1 (fr) * | 2007-06-15 | 2008-12-24 | Xiamen University | Anticorps monoclonaux se liant à l'hémagglutinine du virus de la grippe aviaire du sous type h5 et ses utilisations |
-
2008
- 2008-06-12 MY MYPI20082061A patent/MY160435A/en unknown
-
2009
- 2009-06-10 EP EP09762696.4A patent/EP2300492B1/en not_active Not-in-force
- 2009-06-10 JP JP2011513436A patent/JP5647111B2/ja not_active Expired - Fee Related
- 2009-06-10 US US12/995,889 patent/US8883480B2/en not_active Expired - Fee Related
- 2009-06-10 DK DK09762696.4T patent/DK2300492T3/da active
- 2009-06-10 WO PCT/MY2009/000071 patent/WO2009151313A1/en not_active Ceased
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