JP2014518624A5 - - Google Patents

Download PDF

Info

Publication number
JP2014518624A5
JP2014518624A5 JP2014510535A JP2014510535A JP2014518624A5 JP 2014518624 A5 JP2014518624 A5 JP 2014518624A5 JP 2014510535 A JP2014510535 A JP 2014510535A JP 2014510535 A JP2014510535 A JP 2014510535A JP 2014518624 A5 JP2014518624 A5 JP 2014518624A5
Authority
JP
Japan
Prior art keywords
fragment
neurogranin
antibody
polynucleotide
isolated antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014510535A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014518624A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2012/037774 external-priority patent/WO2012155134A2/en
Publication of JP2014518624A publication Critical patent/JP2014518624A/ja
Publication of JP2014518624A5 publication Critical patent/JP2014518624A5/ja
Pending legal-status Critical Current

Links

JP2014510535A 2011-05-12 2012-05-14 ニューログラニン診断キットのためのアッセイ試薬 Pending JP2014518624A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161485375P 2011-05-12 2011-05-12
US61/485,375 2011-05-12
PCT/US2012/037774 WO2012155134A2 (en) 2011-05-12 2012-05-14 Assay reagents for a neurogranin diagnostic kit

Publications (2)

Publication Number Publication Date
JP2014518624A JP2014518624A (ja) 2014-08-07
JP2014518624A5 true JP2014518624A5 (https=) 2015-07-02

Family

ID=47140053

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014510535A Pending JP2014518624A (ja) 2011-05-12 2012-05-14 ニューログラニン診断キットのためのアッセイ試薬

Country Status (4)

Country Link
US (3) US20140141458A1 (https=)
EP (1) EP2707389B1 (https=)
JP (1) JP2014518624A (https=)
WO (1) WO2012155134A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012051519A2 (en) 2010-10-14 2012-04-19 The Johns Hopkins University Biomarkers of brain injury
US20140141458A1 (en) 2011-05-12 2014-05-22 The Johns Hopkins University Assay reagents for a neurogranin diagnostic kit
HK1206425A1 (en) 2012-03-13 2016-01-08 The Johns Hopkins University Citrullinated brain and neurological proteins as biomarkers of brain injury or neurodegeneration
WO2014193800A2 (en) 2013-05-28 2014-12-04 The Johns Hopkins University Aptamers for the treatment of sickle cell disease
US10534003B2 (en) 2013-07-17 2020-01-14 The Johns Hopkins University Multi-protein biomarker assay for brain injury detection and outcome
FR3025317B1 (fr) * 2014-08-26 2022-09-23 Imabiotech Methode de caracterisation d'un echantillon par imagerie par spectrometrie de masse
EP3242134A1 (en) 2016-05-04 2017-11-08 Euroimmun Medizinische Labordiagnostika AG Assay for the diagnosis of a neurological disease
WO2018217792A1 (en) * 2017-05-23 2018-11-29 Immunarray USA, Inc. Biomarker levels and neuroimaging for detecting, monitoring and treating brain injury or trauma

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
SE462454B (sv) 1988-11-10 1990-06-25 Pharmacia Ab Maetyta foer anvaendning i biosensorer
US6011020A (en) 1990-06-11 2000-01-04 Nexstar Pharmaceuticals, Inc. Nucleic acid ligand complexes
US5683867A (en) 1990-06-11 1997-11-04 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: blended SELEX
US5496938A (en) 1990-06-11 1996-03-05 Nexstar Pharmaceuticals, Inc. Nucleic acid ligands to HIV-RT and HIV-1 rev
US5637459A (en) 1990-06-11 1997-06-10 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: chimeric selex
US5660985A (en) 1990-06-11 1997-08-26 Nexstar Pharmaceuticals, Inc. High affinity nucleic acid ligands containing modified nucleotides
ES2259800T3 (es) 1990-06-11 2006-10-16 Gilead Sciences, Inc. Procedimientos de uso de ligandos de acido nucleico.
US5270163A (en) 1990-06-11 1993-12-14 University Research Corporation Methods for identifying nucleic acid ligands
US5707796A (en) 1990-06-11 1998-01-13 Nexstar Pharmaceuticals, Inc. Method for selecting nucleic acids on the basis of structure
US5567588A (en) 1990-06-11 1996-10-22 University Research Corporation Systematic evolution of ligands by exponential enrichment: Solution SELEX
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US5661016A (en) 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5633425A (en) 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
ATE158021T1 (de) 1990-08-29 1997-09-15 Genpharm Int Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper
US5625126A (en) 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
CA2095633C (en) 1990-12-03 2003-02-04 Lisa J. Garrard Enrichment method for variant proteins with altered binding properties
EP0700521B1 (en) 1993-05-28 2003-06-04 Baylor College Of Medicine Method and mass spectrometer for desorption and ionization of analytes
US5866434A (en) 1994-12-08 1999-02-02 Meso Scale Technology Graphitic nanotubes in luminescence assays
US6673533B1 (en) 1995-03-10 2004-01-06 Meso Scale Technologies, Llc. Multi-array multi-specific electrochemiluminescence testing
JPH11502617A (ja) 1995-03-10 1999-03-02 メソ スケール テクノロジーズ，エルエルシー 多重アレイの多重特異的な電気化学発光試験
US6207369B1 (en) 1995-03-10 2001-03-27 Meso Scale Technologies, Llc Multi-array, multi-specific electrochemiluminescence testing
US6140045A (en) 1995-03-10 2000-10-31 Meso Scale Technologies Multi-array, multi-specific electrochemiluminescence testing
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
US6319670B1 (en) 1995-05-09 2001-11-20 Meso Scale Technology Llp Methods and apparatus for improved luminescence assays using microparticles
NZ516848A (en) 1997-06-20 2004-03-26 Ciphergen Biosystems Inc Retentate chromatography apparatus with applications in biology and medicine
US6413783B1 (en) 1997-09-18 2002-07-02 Meso Scale Technologies, Llc Assay sonication apparatus and methodology
CA2323638A1 (en) 1998-04-03 1999-10-14 Phylos, Inc. Addressable protein arrays
US6406921B1 (en) 1998-07-14 2002-06-18 Zyomyx, Incorporated Protein arrays for high-throughput screening
US6780606B1 (en) 1999-02-26 2004-08-24 Synx Pharma, Inc. Method for diagnosing and distinguishing stroke and diagnostic devices for use therein
WO2000056934A1 (en) 1999-03-24 2000-09-28 Packard Bioscience Company Continuous porous matrix arrays
WO2002024867A2 (en) 2000-09-22 2002-03-28 University Of Aarhus Novel compositions and methods for lymphoma and leukemia
DK1412725T3 (en) 2001-06-29 2019-03-25 Meso Scale Technologies Llc Multi-well plates for LUMINESCENSE TEST MEASUREMENTS
EP1412487B1 (en) 2001-07-30 2010-06-16 Meso Scale Technologies LLC Assay electrodes having immobilized lipid/protein layers and methods of making and using the same
DE60233949D1 (de) 2001-08-20 2009-11-19 Biosite Inc Diagnostische marker für schlaganfall und hirntrauma sowie verfahren zur verwendung davon
AU2002341621A1 (en) 2001-09-10 2003-03-24 Meso Scale Technologies, Llc Methods, reagents, kits and apparatus for protein function analysis
WO2003023380A1 (en) 2001-09-10 2003-03-20 Meso Scale Technologies, Llc Assay buffer, compositions containing the same, and methods of using the same
US20070098728A1 (en) * 2001-09-24 2007-05-03 Pedersen Finn S Novel compositions and methods in cancer
EP1456668B1 (en) 2001-12-05 2007-05-02 Sense Proteomic Limited Protein arrays for allelic variants and uses thereof
US20040014143A1 (en) * 2002-05-29 2004-01-22 Haskins William E. Method and apparatus for detecting and monitoring peptides, and peptides identified therewith
US7036946B1 (en) 2002-09-13 2006-05-02 Rockwell Collins, Inc. LCD backlight with UV light-emitting diodes and planar reactive element
CA2772050C (en) 2002-12-26 2016-09-06 Meso Scale Technologies, Llc. Assay cartridges and methods of using the same
US7981362B2 (en) 2003-11-04 2011-07-19 Meso Scale Technologies, Llc Modular assay plates, reader systems and methods for test measurements
US7396654B2 (en) 2004-04-15 2008-07-08 University Of Florida Research Foundation, Inc. Neural proteins as biomarkers for traumatic brain injury
US7776583B2 (en) 2004-06-03 2010-08-17 Meso Scale Technologies, Llc Methods and apparatuses for conducting assays
EP2514837B1 (en) * 2004-06-25 2016-02-10 Washington University Markers for brain damage
US20060257943A1 (en) 2005-01-25 2006-11-16 Cis Biotech, Inc. Ischemic biomarkers and their use to predict adverse neurological events from surgery
US7884260B2 (en) 2005-06-14 2011-02-08 University Of Chicago Cell-based screen for agents useful for reducing neuronal demyelination or promoting neuronal remyelination
GB2428240A (en) 2005-07-14 2007-01-24 Univ Gen Ve Diagnostic method for brain damage-related disorders
WO2007123976A2 (en) 2006-04-18 2007-11-01 The Board Of Trustees Of The Leland Stanford Junior University Antibody profiling for determination of patient responsiveness
WO2007136617A2 (en) 2006-05-18 2007-11-29 Walter Reed Army Institute Of Research (Wrair) Endothelial-monocyte activating polypeptide ii, a biomarker for use in diagnosis of brain injury
WO2008046509A1 (en) 2006-10-16 2008-04-24 Bayer Schering Pharma Aktiengesellschaft Ltbp2 as a biomarker, therapeutic and diagnostic target
EP2015196A1 (en) 2007-06-28 2009-01-14 Siemens Aktiengesellschaft Programmer interface for manufacturing execution system
WO2009143519A2 (en) * 2008-05-23 2009-11-26 The Johns Hopkins University Biomarkers for myocardial ischemia
JP5781436B2 (ja) 2008-08-11 2015-09-24 バンヤン・バイオマーカーズ・インコーポレーテッド 神経学的状態のバイオマーカー検出方法およびアッセイ
GB201008541D0 (en) 2010-05-21 2010-07-07 Univ Geneve Diagnostic methods
US20140141458A1 (en) 2011-05-12 2014-05-22 The Johns Hopkins University Assay reagents for a neurogranin diagnostic kit

Similar Documents

Publication Publication Date Title
JP2014518624A5 (https=)
JP7022969B2 (ja) ＳＡＲＳ－ＣｏＶ－２感染症を診断するための方法および試薬
JP2014113150A5 (https=)
RU2014108048A (ru) Способ обнаружения рака поджелудочной железы
US10114028B2 (en) Biomarkers for pneumonia and acute decompensated heart failure
CN112105640A (zh) 检测神经退行性变的测定
JP2014509853A5 (https=)
RU2014149332A (ru) Антитела против клаудина 18.2 для диагностики рака
JP2011217747A5 (https=)
IL212056A0 (en) Monoclonal antibodies and methods for their use in the detection of cervical disease
JP2017505436A5 (https=)
CN104769433B (zh) 诊断或监测肾功能或者诊断肾功能异常的方法
CN105399827B (zh) Wasabi蛋白纳米抗体及其编码序列与应用
JP2010536043A5 (https=)
JP2009544284A5 (https=)
JP2020516603A5 (https=)
RU2019113127A (ru) REP белок в качестве белкового антигена для диагностических анализов
JP2019531716A5 (https=)
JP2018527895A5 (https=)
JP2024534348A5 (https=)
JP2014509860A5 (https=)
EP4479434A2 (en) Growth hormone receptor targeting polypeptides
Zhou et al. Plasma IgG aggregates as biomarkers for multiple sclerosis
JP2018520127A5 (https=)
CN115485392A (zh) 用于鉴别配体阻断性抗体及用于确定抗体效价的方法