JP2017530125A5 - - Google Patents

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Publication number
JP2017530125A5
JP2017530125A5 JP2017516101A JP2017516101A JP2017530125A5 JP 2017530125 A5 JP2017530125 A5 JP 2017530125A5 JP 2017516101 A JP2017516101 A JP 2017516101A JP 2017516101 A JP2017516101 A JP 2017516101A JP 2017530125 A5 JP2017530125 A5 JP 2017530125A5
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JP
Japan
Prior art keywords
reactor
carboy
lai
coiled
inch
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JP2017516101A
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English (en)
Japanese (ja)
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JP6754356B2 (ja
JP2017530125A (ja
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Priority claimed from PCT/US2015/052320 external-priority patent/WO2016049509A1/en
Publication of JP2017530125A publication Critical patent/JP2017530125A/ja
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Publication of JP6754356B2 publication Critical patent/JP6754356B2/ja
Publication of JP2017530125A5 publication Critical patent/JP2017530125A5/ja
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JP2017516101A 2014-09-25 2015-09-25 連続流のカルボキシル化反応 Active JP6754356B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462055286P 2014-09-25 2014-09-25
US62/055,286 2014-09-25
PCT/US2015/052320 WO2016049509A1 (en) 2014-09-25 2015-09-25 Continuous flow carboxylation reaction

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019189312A Division JP2020045341A (ja) 2014-09-25 2019-10-16 連続流のカルボキシル化反応

Publications (3)

Publication Number Publication Date
JP2017530125A JP2017530125A (ja) 2017-10-12
JP6754356B2 JP6754356B2 (ja) 2020-09-09
JP2017530125A5 true JP2017530125A5 (enExample) 2020-09-17

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ID=55582084

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017516101A Active JP6754356B2 (ja) 2014-09-25 2015-09-25 連続流のカルボキシル化反応
JP2019189312A Withdrawn JP2020045341A (ja) 2014-09-25 2019-10-16 連続流のカルボキシル化反応

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2019189312A Withdrawn JP2020045341A (ja) 2014-09-25 2019-10-16 連続流のカルボキシル化反応

Country Status (15)

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US (3) US9725413B2 (enExample)
EP (1) EP3197454B1 (enExample)
JP (2) JP6754356B2 (enExample)
CN (1) CN106714801B (enExample)
AU (1) AU2015320349B2 (enExample)
BR (1) BR112017005856A2 (enExample)
CA (1) CA2960392A1 (enExample)
ES (1) ES2857730T3 (enExample)
HU (1) HUE053118T2 (enExample)
IL (2) IL250958B (enExample)
MX (1) MX365010B (enExample)
PL (1) PL3197454T3 (enExample)
PT (1) PT3197454T (enExample)
SA (1) SA517381158B1 (enExample)
WO (1) WO2016049509A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106714801B (zh) 2014-09-25 2021-04-06 诺华股份有限公司 连续流羧基化反应
CN110831938B (zh) * 2017-06-30 2023-08-01 台湾神隆股份有限公司 用于制备立他司特和其中间体的方法
JPWO2019026425A1 (ja) * 2017-07-31 2020-05-28 株式会社カネカ フロー式リアクター
HUE059090T2 (hu) * 2017-11-14 2022-10-28 Albemarle Germany Gmbh Szerves lítium eljárás folyamatos áramlási körülmények között
CN109384717A (zh) * 2018-10-29 2019-02-26 广安凯特制药有限公司 5,7-二氯-1,2,3,4-四氢异喹啉-6-甲酸盐酸盐水合物及其制备方法和用途
CN110724098A (zh) * 2019-11-13 2020-01-24 成都福柯斯医药技术有限公司 一种5,7-二氯-1,2,3,4-四氢异喹啉-6-羧酸盐酸盐的合成方法
CN113845478B (zh) * 2020-12-18 2023-11-21 四川大学 一种中间体及其制备方法和应用
CN113277942B (zh) * 2021-05-25 2024-05-03 都创(上海)医药开发有限公司 一种基于微通道反应技术快速制备5-氯-2-氟-4-(三氟甲基)苯甲酸的方法
CN116239532B (zh) * 2022-12-19 2023-11-07 浙江博崤生物制药有限公司 一种二氯四氢异喹啉羧酸的中间体及其制备方法和应用
CN115872929B (zh) * 2022-12-27 2024-12-03 山东金城柯瑞化学有限公司 芳基类化合物连续羧基化反应制备立他司特中间体的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7767856B2 (en) * 2007-01-25 2010-08-03 Xerox Corporation System and method for producing arylamine compounds
CN101450300A (zh) * 2007-12-05 2009-06-10 海南大学 连续流微反应器及其制备和应用
US8378105B2 (en) * 2009-10-21 2013-02-19 Sarcode Bioscience Inc. Crystalline pharmaceutical and methods of preparation and use thereof
WO2013086585A1 (en) * 2011-12-14 2013-06-20 Commonwealth Scientific And Industrial Research Organisation Raft polymers
EP2877465A4 (en) 2012-07-25 2016-05-11 Sarcode Bioscience Inc LFA-1 HEMMER AND POLYMORPH THEREOF
CN106714801B (zh) * 2014-09-25 2021-04-06 诺华股份有限公司 连续流羧基化反应

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