JP2017526739A5 - - Google Patents
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- Publication number
- JP2017526739A5 JP2017526739A5 JP2017527194A JP2017527194A JP2017526739A5 JP 2017526739 A5 JP2017526739 A5 JP 2017526739A5 JP 2017527194 A JP2017527194 A JP 2017527194A JP 2017527194 A JP2017527194 A JP 2017527194A JP 2017526739 A5 JP2017526739 A5 JP 2017526739A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- biodegradable polymer
- honey
- parts
- filler
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 24
- 229920002988 biodegradable polymer Polymers 0.000 claims 18
- 239000004621 biodegradable polymer Substances 0.000 claims 18
- 235000012907 honey Nutrition 0.000 claims 14
- 239000000945 filler Substances 0.000 claims 12
- 239000006185 dispersion Substances 0.000 claims 11
- 239000012528 membrane Substances 0.000 claims 11
- 239000000835 fiber Substances 0.000 claims 9
- 239000002904 solvent Substances 0.000 claims 8
- 238000000034 method Methods 0.000 claims 7
- 238000004519 manufacturing process Methods 0.000 claims 5
- 210000001519 tissue Anatomy 0.000 claims 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 3
- 238000001523 electrospinning Methods 0.000 claims 3
- LMDZBCPBFSXMTL-UHFFFAOYSA-N 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide Chemical compound CCN=C=NCCCN(C)C LMDZBCPBFSXMTL-UHFFFAOYSA-N 0.000 claims 2
- 102000008186 Collagen Human genes 0.000 claims 2
- 108010035532 Collagen Proteins 0.000 claims 2
- 108010010803 Gelatin Proteins 0.000 claims 2
- 229920001436 collagen Polymers 0.000 claims 2
- 229920000159 gelatin Polymers 0.000 claims 2
- 239000008273 gelatin Substances 0.000 claims 2
- 235000019322 gelatine Nutrition 0.000 claims 2
- 235000011852 gelatine desserts Nutrition 0.000 claims 2
- 229920002463 poly(p-dioxanone) polymer Polymers 0.000 claims 2
- 239000000622 polydioxanone Substances 0.000 claims 2
- 230000001737 promoting effect Effects 0.000 claims 2
- BYEAHWXPCBROCE-UHFFFAOYSA-N 1,1,1,3,3,3-hexafluoropropan-2-ol Chemical compound FC(F)(F)C(O)C(F)(F)F BYEAHWXPCBROCE-UHFFFAOYSA-N 0.000 claims 1
- AZKVWQKMDGGDSV-BCMRRPTOSA-N Genipin Chemical compound COC(=O)C1=CO[C@@H](O)[C@@H]2C(CO)=CC[C@H]12 AZKVWQKMDGGDSV-BCMRRPTOSA-N 0.000 claims 1
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 claims 1
- RHQDFWAXVIIEBN-UHFFFAOYSA-N Trifluoroethanol Chemical group OCC(F)(F)F RHQDFWAXVIIEBN-UHFFFAOYSA-N 0.000 claims 1
- 230000000845 anti-microbial effect Effects 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 claims 1
- AZKVWQKMDGGDSV-UHFFFAOYSA-N genipin Natural products COC(=O)C1=COC(O)C2C(CO)=CCC12 AZKVWQKMDGGDSV-UHFFFAOYSA-N 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 230000035876 healing Effects 0.000 claims 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims 1
- 210000002540 macrophage Anatomy 0.000 claims 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims 1
- 229920000747 poly(lactic acid) Polymers 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 230000008929 regeneration Effects 0.000 claims 1
- 238000011069 regeneration method Methods 0.000 claims 1
- 210000004872 soft tissue Anatomy 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462033599P | 2014-08-05 | 2014-08-05 | |
| US62/033,599 | 2014-08-05 | ||
| PCT/US2015/043789 WO2016022670A1 (en) | 2014-08-05 | 2015-08-05 | Compositions and methods for enhancing healing and regeneration of bone and soft tissue |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017526739A JP2017526739A (ja) | 2017-09-14 |
| JP2017526739A5 true JP2017526739A5 (enExample) | 2018-09-13 |
| JP6861151B2 JP6861151B2 (ja) | 2021-04-21 |
Family
ID=55264490
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017527194A Active JP6861151B2 (ja) | 2014-08-05 | 2015-08-05 | 骨および軟組織の治癒および再生を向上させるための組成物および方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US10258717B2 (enExample) |
| EP (2) | EP3656401A1 (enExample) |
| JP (1) | JP6861151B2 (enExample) |
| KR (1) | KR102511882B1 (enExample) |
| CN (1) | CN107106695B (enExample) |
| AU (1) | AU2015301070B2 (enExample) |
| CA (1) | CA2957263A1 (enExample) |
| ES (1) | ES2760923T3 (enExample) |
| WO (1) | WO2016022670A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2535666B (en) | 2014-04-30 | 2017-03-29 | Matoke Holdings Ltd | Antimicrobial compositions |
| CA2975197A1 (en) * | 2015-02-03 | 2016-08-11 | Matoke Holdings Limited | Antimicrobial fibers and compositions |
| CA3007935A1 (en) * | 2015-12-11 | 2017-06-15 | Poly-Med, Inc. | Synthetic implant device replicating natural tissue structure and methods of making same |
| FR3063886B1 (fr) * | 2017-03-14 | 2019-04-12 | Cousin Biotech | Prothese implantable, notamment pour la chirurgie parietale |
| CN107459662B (zh) * | 2017-09-06 | 2020-09-08 | 青岛农业大学 | 一种纳米复合水凝胶的制备方法 |
| GB201716986D0 (en) | 2017-10-16 | 2017-11-29 | Matoke Holdings Ltd | Antimicrobial compositions |
| CN107715176A (zh) * | 2017-10-31 | 2018-02-23 | 无锡中科光远生物材料有限公司 | 一种促进骨再生的纳米纤维涂层支架的制备方法 |
| CN109432497B (zh) * | 2019-01-05 | 2021-10-19 | 西安点云生物科技有限公司 | 一种甲壳素纳米晶须/羟基磷灰石复合人工骨材料及其制备方法和在3d打印中的应用 |
| CN109675101B (zh) * | 2019-01-05 | 2021-08-10 | 西安点云生物科技有限公司 | 一种甲壳素纳米晶须/羟基磷灰石复合材料及其制备方法和在3d打印人工骨中的应用 |
| CA3142151A1 (en) * | 2019-05-30 | 2020-12-03 | Lifecell Corporation | Biologic breast implant |
| EP3771454B1 (en) * | 2019-07-29 | 2022-11-16 | Shanghai Ninth Peoples Hospital Affiliated Shanghai Jiaotong University School of Medicine | Sealing device for repairing perforation of maxillary sinus mucosa |
| EP4027949A4 (en) * | 2019-09-11 | 2023-06-14 | Warsaw Orthopedic, Inc. | HYDRATABLE COMPOSITIONS COMPRISING MACROPARTICLES AND METHODS OF MAKING THEM |
| CN111407755A (zh) * | 2020-04-30 | 2020-07-14 | 重庆医科大学附属口腔医院 | 视黄酸在牙齿发育中的应用 |
| CN114681678B (zh) * | 2020-12-31 | 2023-04-18 | 广州迈普再生医学科技股份有限公司 | 纳米纤维海绵及其制备方法 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3827561C1 (enExample) * | 1988-08-13 | 1989-12-28 | Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De | |
| ES2167330T3 (es) * | 1992-02-28 | 2002-05-16 | Cohesion Tech Inc | Composiciones ceramicas inyectables y su procedimiento de preparacion y de utilizacion. |
| CN1045719C (zh) * | 1993-04-10 | 1999-10-20 | 北京市西城区华新生化技术研究所 | 口服接骨和治骨质疏松液 |
| CN1140089A (zh) * | 1995-07-07 | 1997-01-15 | 段和平 | 胶原蛋白口服液及其制备方法 |
| US20020081732A1 (en) | 2000-10-18 | 2002-06-27 | Bowlin Gary L. | Electroprocessing in drug delivery and cell encapsulation |
| USRE42755E1 (en) | 1999-12-09 | 2011-09-27 | Apimed Medical Honey Limited | Honey based wound dressing |
| NZ505514A (en) | 2000-06-30 | 2003-02-28 | Bee & Herbal New Zealand Ltd | Method of manufacturing a wound dressing for the application of honey |
| AU2002950744A0 (en) | 2002-08-13 | 2002-09-12 | Medihoney Pty Ltd | Composition |
| US8469036B2 (en) * | 2003-11-07 | 2013-06-25 | U.S. Smokeless Tobacco Company Llc | Tobacco compositions |
| CN1709502A (zh) * | 2005-07-15 | 2005-12-21 | 北京东方兴企食品工业技术有限公司 | 一种复合型关节改善口服液 |
| ITRM20050585A1 (it) * | 2005-11-23 | 2007-05-24 | Mavi Sud S R L | Nanofibrille di chitina spray-dried, metodo di produzione ed usi. |
| CN1994274A (zh) * | 2006-01-04 | 2007-07-11 | 吴天祥 | 仿生精液化妆品 |
| US8524265B2 (en) * | 2006-08-17 | 2013-09-03 | Warsaw Orthopedic, Inc. | Medical implant sheets useful for tissue regeneration |
| EP2079416A4 (en) * | 2006-10-30 | 2012-06-27 | Univ Rutgers | ELECTROSPIN MATRICES FOR DISPENSING HYDROPHILIC AND LIPOPHILLE COMPOUNDS |
| CN101283783B (zh) * | 2007-01-25 | 2011-09-21 | 钟世杰 | 食用保健胶晶及其制备方法 |
| US20090022811A1 (en) * | 2007-03-07 | 2009-01-22 | Legeros Racquel Z | Mineralized guided bone regeneration membranes and methods of making the same |
| US7998498B2 (en) | 2008-01-22 | 2011-08-16 | Michael Szycher | Antimicrobial material and method for making the same |
| US8367094B2 (en) | 2008-01-22 | 2013-02-05 | Michael Szycher | Antimicrobial material and method for making the same |
| JP2010095454A (ja) * | 2008-10-14 | 2010-04-30 | Cyclochem:Kk | 抗菌組成物 |
| GB2474851A (en) * | 2009-10-27 | 2011-05-04 | Univ Bolton | Wound dressing comprising anti-microbial honey encapsulated within biocompatible and biodegradable fibre, and the fibre's production |
| CN101879248A (zh) * | 2010-05-21 | 2010-11-10 | 郭景龙 | 一种具有补血作用的药物组合物 |
| GB2484319A (en) * | 2010-10-06 | 2012-04-11 | Univ Bolton | Electrospinning fibres comprising honey and biocompatible polymer |
| US9101508B2 (en) * | 2011-12-07 | 2015-08-11 | Esmaeil Mirzaei | Electro spun nanofibrous wound dressing and a method of synthesizing the same |
| GB2519072B (en) * | 2013-10-07 | 2019-12-04 | Welland Medical Ltd | Composition comprising collagen and honey |
-
2015
- 2015-08-05 US US14/818,662 patent/US10258717B2/en active Active
- 2015-08-05 CN CN201580054031.8A patent/CN107106695B/zh active Active
- 2015-08-05 KR KR1020177005687A patent/KR102511882B1/ko active Active
- 2015-08-05 AU AU2015301070A patent/AU2015301070B2/en active Active
- 2015-08-05 CA CA2957263A patent/CA2957263A1/en active Pending
- 2015-08-05 EP EP19199349.2A patent/EP3656401A1/en active Pending
- 2015-08-05 EP EP15829615.2A patent/EP3185905B1/en active Active
- 2015-08-05 WO PCT/US2015/043789 patent/WO2016022670A1/en not_active Ceased
- 2015-08-05 JP JP2017527194A patent/JP6861151B2/ja active Active
- 2015-08-05 ES ES15829615T patent/ES2760923T3/es active Active
-
2019
- 2019-01-16 US US16/249,748 patent/US20190224380A1/en active Pending
-
2021
- 2021-04-14 US US17/230,023 patent/US20210308337A1/en active Pending
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