JP6861151B2 - 骨および軟組織の治癒および再生を向上させるための組成物および方法 - Google Patents

骨および軟組織の治癒および再生を向上させるための組成物および方法 Download PDF

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JP6861151B2
JP6861151B2 JP2017527194A JP2017527194A JP6861151B2 JP 6861151 B2 JP6861151 B2 JP 6861151B2 JP 2017527194 A JP2017527194 A JP 2017527194A JP 2017527194 A JP2017527194 A JP 2017527194A JP 6861151 B2 JP6861151 B2 JP 6861151B2
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honey
protein polymer
biodegradable
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JP2017526739A (ja
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ゲーリー リー ボウリン
ゲーリー リー ボウリン
アイザック アンソニー ロドリゲス
アイザック アンソニー ロドリゲス
ブレントン ウォルター バーガー
ブレントン ウォルター バーガー
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ザ ユニバーシティ オブ メンフィス
ザ ユニバーシティ オブ メンフィス
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/222—Gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A—HUMAN NECESSITIES
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
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    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
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    • A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polymers & Plastics (AREA)
JP2017527194A 2014-08-05 2015-08-05 骨および軟組織の治癒および再生を向上させるための組成物および方法 Active JP6861151B2 (ja)

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US201462033599P 2014-08-05 2014-08-05
US62/033,599 2014-08-05
PCT/US2015/043789 WO2016022670A1 (en) 2014-08-05 2015-08-05 Compositions and methods for enhancing healing and regeneration of bone and soft tissue

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JP2017526739A JP2017526739A (ja) 2017-09-14
JP2017526739A5 JP2017526739A5 (enExample) 2018-09-13
JP6861151B2 true JP6861151B2 (ja) 2021-04-21

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US (3) US10258717B2 (enExample)
EP (2) EP3656401A1 (enExample)
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KR (1) KR102511882B1 (enExample)
CN (1) CN107106695B (enExample)
AU (1) AU2015301070B2 (enExample)
CA (1) CA2957263A1 (enExample)
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Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2535666B (en) 2014-04-30 2017-03-29 Matoke Holdings Ltd Antimicrobial compositions
CA2975197A1 (en) * 2015-02-03 2016-08-11 Matoke Holdings Limited Antimicrobial fibers and compositions
CA3007935A1 (en) * 2015-12-11 2017-06-15 Poly-Med, Inc. Synthetic implant device replicating natural tissue structure and methods of making same
FR3063886B1 (fr) * 2017-03-14 2019-04-12 Cousin Biotech Prothese implantable, notamment pour la chirurgie parietale
CN107459662B (zh) * 2017-09-06 2020-09-08 青岛农业大学 一种纳米复合水凝胶的制备方法
GB201716986D0 (en) 2017-10-16 2017-11-29 Matoke Holdings Ltd Antimicrobial compositions
CN107715176A (zh) * 2017-10-31 2018-02-23 无锡中科光远生物材料有限公司 一种促进骨再生的纳米纤维涂层支架的制备方法
CN109432497B (zh) * 2019-01-05 2021-10-19 西安点云生物科技有限公司 一种甲壳素纳米晶须/羟基磷灰石复合人工骨材料及其制备方法和在3d打印中的应用
CN109675101B (zh) * 2019-01-05 2021-08-10 西安点云生物科技有限公司 一种甲壳素纳米晶须/羟基磷灰石复合材料及其制备方法和在3d打印人工骨中的应用
CA3142151A1 (en) * 2019-05-30 2020-12-03 Lifecell Corporation Biologic breast implant
EP3771454B1 (en) * 2019-07-29 2022-11-16 Shanghai Ninth Peoples Hospital Affiliated Shanghai Jiaotong University School of Medicine Sealing device for repairing perforation of maxillary sinus mucosa
EP4027949A4 (en) * 2019-09-11 2023-06-14 Warsaw Orthopedic, Inc. HYDRATABLE COMPOSITIONS COMPRISING MACROPARTICLES AND METHODS OF MAKING THEM
CN111407755A (zh) * 2020-04-30 2020-07-14 重庆医科大学附属口腔医院 视黄酸在牙齿发育中的应用
CN114681678B (zh) * 2020-12-31 2023-04-18 广州迈普再生医学科技股份有限公司 纳米纤维海绵及其制备方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3827561C1 (enExample) * 1988-08-13 1989-12-28 Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De
ES2167330T3 (es) * 1992-02-28 2002-05-16 Cohesion Tech Inc Composiciones ceramicas inyectables y su procedimiento de preparacion y de utilizacion.
CN1045719C (zh) * 1993-04-10 1999-10-20 北京市西城区华新生化技术研究所 口服接骨和治骨质疏松液
CN1140089A (zh) * 1995-07-07 1997-01-15 段和平 胶原蛋白口服液及其制备方法
US20020081732A1 (en) 2000-10-18 2002-06-27 Bowlin Gary L. Electroprocessing in drug delivery and cell encapsulation
USRE42755E1 (en) 1999-12-09 2011-09-27 Apimed Medical Honey Limited Honey based wound dressing
NZ505514A (en) 2000-06-30 2003-02-28 Bee & Herbal New Zealand Ltd Method of manufacturing a wound dressing for the application of honey
AU2002950744A0 (en) 2002-08-13 2002-09-12 Medihoney Pty Ltd Composition
US8469036B2 (en) * 2003-11-07 2013-06-25 U.S. Smokeless Tobacco Company Llc Tobacco compositions
CN1709502A (zh) * 2005-07-15 2005-12-21 北京东方兴企食品工业技术有限公司 一种复合型关节改善口服液
ITRM20050585A1 (it) * 2005-11-23 2007-05-24 Mavi Sud S R L Nanofibrille di chitina spray-dried, metodo di produzione ed usi.
CN1994274A (zh) * 2006-01-04 2007-07-11 吴天祥 仿生精液化妆品
US8524265B2 (en) * 2006-08-17 2013-09-03 Warsaw Orthopedic, Inc. Medical implant sheets useful for tissue regeneration
EP2079416A4 (en) * 2006-10-30 2012-06-27 Univ Rutgers ELECTROSPIN MATRICES FOR DISPENSING HYDROPHILIC AND LIPOPHILLE COMPOUNDS
CN101283783B (zh) * 2007-01-25 2011-09-21 钟世杰 食用保健胶晶及其制备方法
US20090022811A1 (en) * 2007-03-07 2009-01-22 Legeros Racquel Z Mineralized guided bone regeneration membranes and methods of making the same
US7998498B2 (en) 2008-01-22 2011-08-16 Michael Szycher Antimicrobial material and method for making the same
US8367094B2 (en) 2008-01-22 2013-02-05 Michael Szycher Antimicrobial material and method for making the same
JP2010095454A (ja) * 2008-10-14 2010-04-30 Cyclochem:Kk 抗菌組成物
GB2474851A (en) * 2009-10-27 2011-05-04 Univ Bolton Wound dressing comprising anti-microbial honey encapsulated within biocompatible and biodegradable fibre, and the fibre's production
CN101879248A (zh) * 2010-05-21 2010-11-10 郭景龙 一种具有补血作用的药物组合物
GB2484319A (en) * 2010-10-06 2012-04-11 Univ Bolton Electrospinning fibres comprising honey and biocompatible polymer
US9101508B2 (en) * 2011-12-07 2015-08-11 Esmaeil Mirzaei Electro spun nanofibrous wound dressing and a method of synthesizing the same
GB2519072B (en) * 2013-10-07 2019-12-04 Welland Medical Ltd Composition comprising collagen and honey

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CA2957263A1 (en) 2016-02-11
NZ729417A (en) 2024-02-23
US10258717B2 (en) 2019-04-16
CN107106695A (zh) 2017-08-29
US20210308337A1 (en) 2021-10-07
WO2016022670A1 (en) 2016-02-11
KR20170042621A (ko) 2017-04-19
EP3185905A4 (en) 2018-04-04
EP3185905A1 (en) 2017-07-05
JP2017526739A (ja) 2017-09-14
EP3185905B1 (en) 2019-09-25
AU2015301070A1 (en) 2017-03-16
KR102511882B1 (ko) 2023-03-17
BR112017002259A2 (pt) 2017-11-21
EP3656401A1 (en) 2020-05-27
CN107106695B (zh) 2021-02-23
US20160038646A1 (en) 2016-02-11
US20190224380A1 (en) 2019-07-25
ES2760923T3 (es) 2020-05-18

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