JP2017526728A - 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト - Google Patents
炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト Download PDFInfo
- Publication number
- JP2017526728A JP2017526728A JP2017514446A JP2017514446A JP2017526728A JP 2017526728 A JP2017526728 A JP 2017526728A JP 2017514446 A JP2017514446 A JP 2017514446A JP 2017514446 A JP2017514446 A JP 2017514446A JP 2017526728 A JP2017526728 A JP 2017526728A
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- Prior art keywords
- montelukast
- levocetirizine
- virus
- combination
- disease
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462050668P | 2014-09-15 | 2014-09-15 | |
| US62/050,668 | 2014-09-15 | ||
| PCT/US2015/049767 WO2016044095A1 (en) | 2014-09-15 | 2015-09-11 | Levocetirizine and montelukast in the treatment of inflammation mediated conditions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020070422A Division JP2020109128A (ja) | 2014-09-15 | 2020-04-09 | 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017526728A true JP2017526728A (ja) | 2017-09-14 |
| JP2017526728A5 JP2017526728A5 (https=) | 2018-10-11 |
Family
ID=55533713
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017514446A Pending JP2017526728A (ja) | 2014-09-15 | 2015-09-11 | 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト |
| JP2020070422A Pending JP2020109128A (ja) | 2014-09-15 | 2020-04-09 | 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020070422A Pending JP2020109128A (ja) | 2014-09-15 | 2020-04-09 | 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト |
Country Status (4)
| Country | Link |
|---|---|
| US (4) | US9925183B2 (https=) |
| EP (1) | EP3193875B1 (https=) |
| JP (2) | JP2017526728A (https=) |
| WO (1) | WO2016044095A1 (https=) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019209035A1 (ko) * | 2018-04-27 | 2019-10-31 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| KR20190125943A (ko) * | 2018-04-27 | 2019-11-07 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| JP2022500437A (ja) * | 2018-09-14 | 2022-01-04 | ジャンイン ユスン ファーマシューティカル カンパニー,リミテッド | モンテルカストおよびペプチドの新規接合体 |
| JP2023517537A (ja) * | 2020-03-02 | 2023-04-26 | ファルマ、マール、ソシエダード、アノニマ | 自己免疫状態に使用するための化合物 |
| JP2023517536A (ja) * | 2020-03-02 | 2023-04-26 | ファルマ、マール、ソシエダード、アノニマ | 炎症状態に使用するための化合物 |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20130050952A (ko) | 2010-06-16 | 2013-05-16 | 브루스 챈들러 메이 | 인플루엔자, 감기 및 염증의 치료에서 레보세티리진 및 몬테루카스트의 용도 |
| RU2015134423A (ru) | 2013-03-13 | 2017-04-26 | Инфламматори Респонс Ресёрч, Инк. | Применение левоцитиризина и монтелукаста при лечении аутоиммуных расстройств |
| WO2014164285A2 (en) | 2013-03-13 | 2014-10-09 | Inflammatory Response Research, Inc. | Use of levocetirizine and montelukast in the treatment of vasculitis |
| MX382776B (es) | 2013-03-13 | 2025-03-13 | Inflammatory Response Res Inc | Uso de levocetirizina y montelukast en el tratamiento de lesion traumatica. |
| WO2016044095A1 (en) | 2014-09-15 | 2016-03-24 | Inflammatory Response Research, Inc. | Levocetirizine and montelukast in the treatment of inflammation mediated conditions |
| AU2019334202A1 (en) | 2018-09-06 | 2021-03-25 | Innopharmascreen, Inc. | Methods and compositions for treatment of asthma or parkinson's disease |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| WO2021236518A1 (en) * | 2020-05-19 | 2021-11-25 | IRR, Inc. | Levocetirizine and montelukast in the treatment of sepsis and symptoms thereof |
| KR102935859B1 (ko) | 2022-08-12 | 2026-03-06 | 아주대학교산학협력단 | 펙소페나딘을 포함하는 퇴행성 신경질환의 예방, 개선 또는 치료용 조성물 |
Citations (6)
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| US20040180868A1 (en) * | 2003-03-12 | 2004-09-16 | Mullally John P. | Composition and method for treating inflammations by reducing C-reactive protein |
| US20050256131A1 (en) * | 2002-05-24 | 2005-11-17 | Carl-Fr Coester | Pharmaceutical active substance combination and the use thereof |
| JP2013528654A (ja) * | 2010-06-16 | 2013-07-11 | ブルース・チャンドラー・メイ | インフルエンザ、一般的な感冒および炎症の治療におけるレボセチリジンおよびモンテルカストの使用 |
| WO2013148366A1 (en) * | 2012-03-27 | 2013-10-03 | Duke Unversity | Compositions and methods for the prevention and treatment of mast cell-induced vascular leakage |
| CN103505731A (zh) * | 2012-06-15 | 2014-01-15 | 中国药科大学 | 1型半胱氨酰白三烯受体拮抗剂在制备用于治疗阿尔茨海默病的药物中的用途 |
| WO2014090990A1 (en) * | 2012-12-13 | 2014-06-19 | Ludwig Aigner | Leukotriene pathway antagonists for the treatment of dementia, cognitive deficits in parkinson's disease and/or learning and memory deficiencies in parkinson's disease |
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-
2015
- 2015-09-11 WO PCT/US2015/049767 patent/WO2016044095A1/en not_active Ceased
- 2015-09-11 EP EP15841696.6A patent/EP3193875B1/en active Active
- 2015-09-11 JP JP2017514446A patent/JP2017526728A/ja active Pending
-
2017
- 2017-03-06 US US15/450,840 patent/US9925183B2/en active Active
-
2018
- 2018-02-13 US US15/895,918 patent/US10195193B2/en active Active
- 2018-12-18 US US16/224,573 patent/US10792281B2/en active Active
-
2020
- 2020-04-09 JP JP2020070422A patent/JP2020109128A/ja active Pending
- 2020-08-31 US US17/007,902 patent/US11590125B2/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050256131A1 (en) * | 2002-05-24 | 2005-11-17 | Carl-Fr Coester | Pharmaceutical active substance combination and the use thereof |
| US20040180868A1 (en) * | 2003-03-12 | 2004-09-16 | Mullally John P. | Composition and method for treating inflammations by reducing C-reactive protein |
| JP2013528654A (ja) * | 2010-06-16 | 2013-07-11 | ブルース・チャンドラー・メイ | インフルエンザ、一般的な感冒および炎症の治療におけるレボセチリジンおよびモンテルカストの使用 |
| WO2013148366A1 (en) * | 2012-03-27 | 2013-10-03 | Duke Unversity | Compositions and methods for the prevention and treatment of mast cell-induced vascular leakage |
| CN103505731A (zh) * | 2012-06-15 | 2014-01-15 | 中国药科大学 | 1型半胱氨酰白三烯受体拮抗剂在制备用于治疗阿尔茨海默病的药物中的用途 |
| WO2014090990A1 (en) * | 2012-12-13 | 2014-06-19 | Ludwig Aigner | Leukotriene pathway antagonists for the treatment of dementia, cognitive deficits in parkinson's disease and/or learning and memory deficiencies in parkinson's disease |
Non-Patent Citations (1)
| Title |
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| NEUROPHARMCOLOGY, vol. 79, JPN6019019029, April 2014 (2014-04-01), pages 707 - 714, ISSN: 0004041719 * |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019209035A1 (ko) * | 2018-04-27 | 2019-10-31 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| KR20190125943A (ko) * | 2018-04-27 | 2019-11-07 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| KR20200116069A (ko) * | 2018-04-27 | 2020-10-08 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| KR20200116068A (ko) * | 2018-04-27 | 2020-10-08 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| KR102269665B1 (ko) | 2018-04-27 | 2021-06-28 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| KR102269664B1 (ko) | 2018-04-27 | 2021-06-28 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| KR102269663B1 (ko) | 2018-04-27 | 2021-06-28 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| JP2022500437A (ja) * | 2018-09-14 | 2022-01-04 | ジャンイン ユスン ファーマシューティカル カンパニー,リミテッド | モンテルカストおよびペプチドの新規接合体 |
| JP7759693B2 (ja) | 2018-09-14 | 2025-10-24 | ジャンイン ユスン ファーマシューティカル カンパニー,リミテッド | モンテルカストおよびペプチドの新規接合体 |
| KR102946621B1 (ko) * | 2018-09-14 | 2026-04-01 | 장인 우선 파마슈티컬 컴퍼니 리미티드 | 몬테루카스트와 펩티드의 새로운 접합체 |
| JP2023517537A (ja) * | 2020-03-02 | 2023-04-26 | ファルマ、マール、ソシエダード、アノニマ | 自己免疫状態に使用するための化合物 |
| JP2023517536A (ja) * | 2020-03-02 | 2023-04-26 | ファルマ、マール、ソシエダード、アノニマ | 炎症状態に使用するための化合物 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3193875A4 (en) | 2018-05-23 |
| US9925183B2 (en) | 2018-03-27 |
| JP2020109128A (ja) | 2020-07-16 |
| US20180169091A1 (en) | 2018-06-21 |
| EP3193875A1 (en) | 2017-07-26 |
| WO2016044095A1 (en) | 2016-03-24 |
| EP3193875B1 (en) | 2022-02-16 |
| US10195193B2 (en) | 2019-02-05 |
| US20190201393A1 (en) | 2019-07-04 |
| US20170173001A1 (en) | 2017-06-22 |
| US20210177835A1 (en) | 2021-06-17 |
| US11590125B2 (en) | 2023-02-28 |
| US10792281B2 (en) | 2020-10-06 |
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