JP2017526728A5 - - Google Patents
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- Publication number
- JP2017526728A5 JP2017526728A5 JP2017514446A JP2017514446A JP2017526728A5 JP 2017526728 A5 JP2017526728 A5 JP 2017526728A5 JP 2017514446 A JP2017514446 A JP 2017514446A JP 2017514446 A JP2017514446 A JP 2017514446A JP 2017526728 A5 JP2017526728 A5 JP 2017526728A5
- Authority
- JP
- Japan
- Prior art keywords
- montelukast
- medicament
- combination
- disease
- virus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 claims 19
- UCHDWCPVSPXUMX-TZIWLTJVSA-N Montelukast Chemical compound CC(C)(O)C1=CC=CC=C1CC[C@H](C=1C=C(\C=C\C=2N=C3C=C(Cl)C=CC3=CC=2)C=CC=1)SCC1(CC(O)=O)CC1 UCHDWCPVSPXUMX-TZIWLTJVSA-N 0.000 claims 13
- 229960005127 montelukast Drugs 0.000 claims 13
- ZKLPARSLTMPFCP-OAQYLSRUSA-N 2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]-1-piperazinyl]ethoxy]acetic acid Chemical compound C1CN(CCOCC(=O)O)CCN1[C@@H](C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 ZKLPARSLTMPFCP-OAQYLSRUSA-N 0.000 claims 9
- 229960001508 levocetirizine Drugs 0.000 claims 9
- 208000036142 Viral infection Diseases 0.000 claims 4
- 230000009385 viral infection Effects 0.000 claims 4
- 208000024827 Alzheimer disease Diseases 0.000 claims 3
- 206010012289 Dementia Diseases 0.000 claims 3
- 241000725619 Dengue virus Species 0.000 claims 3
- 241001115402 Ebolavirus Species 0.000 claims 3
- 201000011240 Frontotemporal dementia Diseases 0.000 claims 3
- 208000023105 Huntington disease Diseases 0.000 claims 3
- 208000009829 Lewy Body Disease Diseases 0.000 claims 3
- 201000002832 Lewy body dementia Diseases 0.000 claims 3
- 208000018737 Parkinson disease Diseases 0.000 claims 3
- 241000710886 West Nile virus Species 0.000 claims 3
- 241000710772 Yellow fever virus Species 0.000 claims 3
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 claims 3
- 230000001404 mediated effect Effects 0.000 claims 3
- 230000004770 neurodegeneration Effects 0.000 claims 3
- 208000015122 neurodegenerative disease Diseases 0.000 claims 3
- 229940051021 yellow-fever virus Drugs 0.000 claims 3
- 208000004006 Tick-borne encephalitis Diseases 0.000 claims 2
- 101000979342 Homo sapiens Nuclear factor NF-kappa-B p105 subunit Proteins 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 208000012902 Nervous system disease Diseases 0.000 claims 1
- 208000025966 Neurological disease Diseases 0.000 claims 1
- 102100023050 Nuclear factor NF-kappa-B p105 subunit Human genes 0.000 claims 1
- 241000580858 Simian-Human immunodeficiency virus Species 0.000 claims 1
- 241000710771 Tick-borne encephalitis virus Species 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 238000007912 intraperitoneal administration Methods 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 150000003431 steroids Chemical class 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 238000013268 sustained release Methods 0.000 claims 1
- 239000012730 sustained-release form Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462050668P | 2014-09-15 | 2014-09-15 | |
| US62/050,668 | 2014-09-15 | ||
| PCT/US2015/049767 WO2016044095A1 (en) | 2014-09-15 | 2015-09-11 | Levocetirizine and montelukast in the treatment of inflammation mediated conditions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020070422A Division JP2020109128A (ja) | 2014-09-15 | 2020-04-09 | 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017526728A JP2017526728A (ja) | 2017-09-14 |
| JP2017526728A5 true JP2017526728A5 (https=) | 2018-10-11 |
Family
ID=55533713
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017514446A Pending JP2017526728A (ja) | 2014-09-15 | 2015-09-11 | 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト |
| JP2020070422A Pending JP2020109128A (ja) | 2014-09-15 | 2020-04-09 | 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020070422A Pending JP2020109128A (ja) | 2014-09-15 | 2020-04-09 | 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト |
Country Status (4)
| Country | Link |
|---|---|
| US (4) | US9925183B2 (https=) |
| EP (1) | EP3193875B1 (https=) |
| JP (2) | JP2017526728A (https=) |
| WO (1) | WO2016044095A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20130050952A (ko) | 2010-06-16 | 2013-05-16 | 브루스 챈들러 메이 | 인플루엔자, 감기 및 염증의 치료에서 레보세티리진 및 몬테루카스트의 용도 |
| RU2015134423A (ru) | 2013-03-13 | 2017-04-26 | Инфламматори Респонс Ресёрч, Инк. | Применение левоцитиризина и монтелукаста при лечении аутоиммуных расстройств |
| WO2014164285A2 (en) | 2013-03-13 | 2014-10-09 | Inflammatory Response Research, Inc. | Use of levocetirizine and montelukast in the treatment of vasculitis |
| MX382776B (es) | 2013-03-13 | 2025-03-13 | Inflammatory Response Res Inc | Uso de levocetirizina y montelukast en el tratamiento de lesion traumatica. |
| WO2016044095A1 (en) | 2014-09-15 | 2016-03-24 | Inflammatory Response Research, Inc. | Levocetirizine and montelukast in the treatment of inflammation mediated conditions |
| CN112040954A (zh) * | 2018-04-27 | 2020-12-04 | 雷莫内克斯生物制药有限公司 | 用于预防或治疗黄病毒感染症的药物组合物 |
| WO2019209035A1 (ko) * | 2018-04-27 | 2019-10-31 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| AU2019334202A1 (en) | 2018-09-06 | 2021-03-25 | Innopharmascreen, Inc. | Methods and compositions for treatment of asthma or parkinson's disease |
| CN111601618A (zh) * | 2018-09-14 | 2020-08-28 | 江阴贝瑞森制药有限公司 | 孟鲁司特与肽的新缀合物 |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| CA3169544A1 (en) * | 2020-03-02 | 2021-09-10 | Pablo Aviles Marin | Compounds for use in inflammatory conditions |
| US20230158104A1 (en) * | 2020-03-02 | 2023-05-25 | Pharma Mar, S.A. | Compounds for use in autoimmune conditions |
| WO2021236518A1 (en) * | 2020-05-19 | 2021-11-25 | IRR, Inc. | Levocetirizine and montelukast in the treatment of sepsis and symptoms thereof |
| KR102935859B1 (ko) | 2022-08-12 | 2026-03-06 | 아주대학교산학협력단 | 펙소페나딘을 포함하는 퇴행성 신경질환의 예방, 개선 또는 치료용 조성물 |
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| MX382776B (es) | 2013-03-13 | 2025-03-13 | Inflammatory Response Res Inc | Uso de levocetirizina y montelukast en el tratamiento de lesion traumatica. |
| RU2015134423A (ru) | 2013-03-13 | 2017-04-26 | Инфламматори Респонс Ресёрч, Инк. | Применение левоцитиризина и монтелукаста при лечении аутоиммуных расстройств |
| WO2014164285A2 (en) | 2013-03-13 | 2014-10-09 | Inflammatory Response Research, Inc. | Use of levocetirizine and montelukast in the treatment of vasculitis |
| RU2705097C2 (ru) | 2013-03-13 | 2019-11-05 | Ирр, Инк. | Применение левоцетиризина и монтелукаста при лечении анафилаксии |
| US9371282B2 (en) | 2013-05-17 | 2016-06-21 | Centrexion Therapeutics Corporation | Somatostatin receptor subtype 4 (SSTR4) agonists |
| WO2016044095A1 (en) | 2014-09-15 | 2016-03-24 | Inflammatory Response Research, Inc. | Levocetirizine and montelukast in the treatment of inflammation mediated conditions |
| WO2017210417A1 (en) | 2016-06-03 | 2017-12-07 | Inflammatory Response Research, Inc. | Levocetirizine and montelukast in the treatment of radiation-mediated conditions |
| WO2021236518A1 (en) | 2020-05-19 | 2021-11-25 | IRR, Inc. | Levocetirizine and montelukast in the treatment of sepsis and symptoms thereof |
-
2015
- 2015-09-11 WO PCT/US2015/049767 patent/WO2016044095A1/en not_active Ceased
- 2015-09-11 EP EP15841696.6A patent/EP3193875B1/en active Active
- 2015-09-11 JP JP2017514446A patent/JP2017526728A/ja active Pending
-
2017
- 2017-03-06 US US15/450,840 patent/US9925183B2/en active Active
-
2018
- 2018-02-13 US US15/895,918 patent/US10195193B2/en active Active
- 2018-12-18 US US16/224,573 patent/US10792281B2/en active Active
-
2020
- 2020-04-09 JP JP2020070422A patent/JP2020109128A/ja active Pending
- 2020-08-31 US US17/007,902 patent/US11590125B2/en active Active
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