JP2017524372A5 - - Google Patents
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- JP2017524372A5 JP2017524372A5 JP2017515021A JP2017515021A JP2017524372A5 JP 2017524372 A5 JP2017524372 A5 JP 2017524372A5 JP 2017515021 A JP2017515021 A JP 2017515021A JP 2017515021 A JP2017515021 A JP 2017515021A JP 2017524372 A5 JP2017524372 A5 JP 2017524372A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- tcr
- nos
- isolated
- purified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 102000016266 T-Cell Antigen Receptors Human genes 0.000 claims 41
- 108091008874 T cell receptors Proteins 0.000 claims 40
- 229920001184 polypeptide Polymers 0.000 claims 18
- 102000004196 processed proteins & peptides Human genes 0.000 claims 18
- 108090000765 processed proteins & peptides Proteins 0.000 claims 18
- 125000003275 alpha amino acid group Chemical group 0.000 claims 17
- 102000004169 proteins and genes Human genes 0.000 claims 17
- 108090000623 proteins and genes Proteins 0.000 claims 17
- 210000004027 cell Anatomy 0.000 claims 12
- 150000007523 nucleic acids Chemical group 0.000 claims 8
- 239000000427 antigen Substances 0.000 claims 7
- 108091007433 antigens Proteins 0.000 claims 7
- 102000036639 antigens Human genes 0.000 claims 7
- 238000003259 recombinant expression Methods 0.000 claims 7
- 239000013604 expression vector Substances 0.000 claims 6
- 108020004707 nucleic acids Proteins 0.000 claims 6
- 102000039446 nucleic acids Human genes 0.000 claims 6
- 239000002773 nucleotide Substances 0.000 claims 6
- 125000003729 nucleotide group Chemical group 0.000 claims 6
- 241000701806 Human papillomavirus Species 0.000 claims 5
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 241000124008 Mammalia Species 0.000 claims 4
- 241000341655 Human papillomavirus type 16 Species 0.000 claims 3
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 201000011510 cancer Diseases 0.000 claims 3
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 208000006994 Precancerous Conditions Diseases 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 101000767631 Human papillomavirus type 16 Protein E7 Proteins 0.000 claims 1
- 208000002471 Penile Neoplasms Diseases 0.000 claims 1
- 208000004354 Vulvar Neoplasms Diseases 0.000 claims 1
- 210000002255 anal canal Anatomy 0.000 claims 1
- 210000003679 cervix uteri Anatomy 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 108020001507 fusion proteins Proteins 0.000 claims 1
- 102000037865 fusion proteins Human genes 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 210000001215 vagina Anatomy 0.000 claims 1
- 239000013598 vector Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462004335P | 2014-05-29 | 2014-05-29 | |
| US62/004,335 | 2014-05-29 | ||
| PCT/US2015/033129 WO2015184228A1 (en) | 2014-05-29 | 2015-05-29 | Anti-human papillomavirus 16 e7 t cell receptors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020127833A Division JP6997267B2 (ja) | 2014-05-29 | 2020-07-29 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017524372A JP2017524372A (ja) | 2017-08-31 |
| JP2017524372A5 true JP2017524372A5 (OSRAM) | 2018-06-28 |
| JP6742991B2 JP6742991B2 (ja) | 2020-08-19 |
Family
ID=53396593
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017515021A Active JP6742991B2 (ja) | 2014-05-29 | 2015-05-29 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
| JP2020127833A Active JP6997267B2 (ja) | 2014-05-29 | 2020-07-29 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
| JP2021203953A Active JP7291196B2 (ja) | 2014-05-29 | 2021-12-16 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
| JP2023091878A Active JP7535158B2 (ja) | 2014-05-29 | 2023-06-02 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
| JP2024126652A Active JP7744479B2 (ja) | 2014-05-29 | 2024-08-02 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020127833A Active JP6997267B2 (ja) | 2014-05-29 | 2020-07-29 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
| JP2021203953A Active JP7291196B2 (ja) | 2014-05-29 | 2021-12-16 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
| JP2023091878A Active JP7535158B2 (ja) | 2014-05-29 | 2023-06-02 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
| JP2024126652A Active JP7744479B2 (ja) | 2014-05-29 | 2024-08-02 | 抗ヒトパピローマウイルス１６ ｅ７ ｔ細胞受容体 |
Country Status (21)
| Country | Link |
|---|---|
| US (4) | US10174098B2 (OSRAM) |
| EP (3) | EP4609876A2 (OSRAM) |
| JP (5) | JP6742991B2 (OSRAM) |
| KR (2) | KR102618267B1 (OSRAM) |
| CN (2) | CN106661098B (OSRAM) |
| AU (5) | AU2015266818B2 (OSRAM) |
| BR (1) | BR112016027805A2 (OSRAM) |
| CA (1) | CA2950192A1 (OSRAM) |
| CY (1) | CY1122790T1 (OSRAM) |
| DK (1) | DK3149031T3 (OSRAM) |
| ES (1) | ES2784237T3 (OSRAM) |
| HR (1) | HRP20200376T1 (OSRAM) |
| IL (3) | IL290655B2 (OSRAM) |
| LT (1) | LT3149031T (OSRAM) |
| MX (2) | MX375379B (OSRAM) |
| PL (1) | PL3149031T3 (OSRAM) |
| PT (1) | PT3149031T (OSRAM) |
| SA (1) | SA516380394B1 (OSRAM) |
| SI (1) | SI3149031T1 (OSRAM) |
| SM (1) | SMT202000143T1 (OSRAM) |
| WO (1) | WO2015184228A1 (OSRAM) |
Families Citing this family (70)
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| WO2016179006A1 (en) | 2015-05-01 | 2016-11-10 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of isolating t cells and t cell receptors having antigenic specificity for a cancer-specific mutation from peripheral blood |
| EP4212547A1 (en) | 2015-12-03 | 2023-07-19 | Juno Therapeutics, Inc. | Modified chimeric receptors and related compositions and methods |
| US10975436B2 (en) | 2016-01-05 | 2021-04-13 | Diamir, Llc | Methods of using miRNA from bodily fluids for diagnosis and monitoring of neurodevelopmental disorders |
| WO2017139199A1 (en) | 2016-02-10 | 2017-08-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Inducible arginase |
| ES2912269T3 (es) | 2016-09-27 | 2022-05-25 | Cero Therapeutics Inc | Moléculas de receptor de engullimiento quimérico |
| KR20190062505A (ko) * | 2016-10-03 | 2019-06-05 | 주노 쎄러퓨티크스 인코퍼레이티드 | Hpv-특이적 결합 분자 |
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| EP3749770B9 (en) | 2018-02-09 | 2025-12-17 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Tethered interleukin-15 and interleukin-21 |
| JP7444781B2 (ja) | 2018-03-28 | 2024-03-06 | セロ・セラピューティクス・インコーポレイテッド | 細胞免疫療法組成物およびその使用 |
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| CA3093969A1 (en) | 2018-03-28 | 2019-10-03 | Cero Therapeutics, Inc. | Expression vectors for chimeric engulfment receptors, genetically modified host cells, and uses thereof |
| KR102764123B1 (ko) * | 2018-04-05 | 2025-02-05 | 주노 쎄러퓨티크스 인코퍼레이티드 | Τ 세포 수용체 및 이를 발현하는 조작된 세포 |
| WO2019195491A1 (en) | 2018-04-05 | 2019-10-10 | Juno Therapeutics, Inc. | T cells expressing a recombinant receptor, related polynucleotides and methods |
| JP7589047B2 (ja) | 2018-04-05 | 2024-11-25 | ジュノー セラピューティクス インコーポレイテッド | 組換え受容体を発現する細胞の作製方法および関連組成物 |
| US12415845B2 (en) | 2018-04-24 | 2025-09-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of producing T cell populations using hydroxycitric acid and/or a salt thereof |
| EP3810780A1 (en) * | 2018-06-22 | 2021-04-28 | Kite Pharma Eu B.V. | Compositions and methods for making engineered t cells |
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| EP4609876A2 (en) * | 2014-05-29 | 2025-09-03 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Anti-human papillomavirus 16 e7 t cell receptors |
-
2015
- 2015-05-29 EP EP25187143.0A patent/EP4609876A2/en active Pending
- 2015-05-29 PL PL15729004T patent/PL3149031T3/pl unknown
- 2015-05-29 KR KR1020227032043A patent/KR102618267B1/ko active Active
- 2015-05-29 MX MX2016015383A patent/MX375379B/es active IP Right Grant
- 2015-05-29 ES ES15729004T patent/ES2784237T3/es active Active
- 2015-05-29 JP JP2017515021A patent/JP6742991B2/ja active Active
- 2015-05-29 HR HRP20200376TT patent/HRP20200376T1/hr unknown
- 2015-05-29 CN CN201580031789.XA patent/CN106661098B/zh active Active
- 2015-05-29 SM SM20200143T patent/SMT202000143T1/it unknown
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