EA202190693A1 - Способы анализа масс-спектрометрии композиций модифицированных клеток - Google Patents

Способы анализа масс-спектрометрии композиций модифицированных клеток

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EA202190693A1
EA202190693A1 EA202190693A EA202190693A EA202190693A1 EA 202190693 A1 EA202190693 A1 EA 202190693A1 EA 202190693 A EA202190693 A EA 202190693A EA 202190693 A EA202190693 A EA 202190693A EA 202190693 A1 EA202190693 A1 EA 202190693A1
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mass spectrometry
methods
modified cell
cell composition
profile
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EA202190693A
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English (en)
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Кеннет Майо Прентис
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Джуно Терапьютикс, Инк.
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    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
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Abstract

Настоящее изобретение относится к способам получения профиля масс-спектрометрии (MS) образца из композиции клеток, такой как композиция модифицированных клеток. В некоторых вариантах осуществления профиль масс-спектрометрии включает данные, основанные на одном или более анализах или способах масс-спектрометрии. Настоящее изобретение относится также к способам на основании профилей масс-спектрометрии одного или более образцов таких композиций клеток: идентификации профиля масс-спектрометрии (MS) композиции генетически модифицированных клеток, содержащий иммуноциты, содержащие рекомбинантный рецептор, посредством сравнения с эталонным профилем масс-спектрометрии; характеризации способа получения композиции генетически модифицированных клеток; оценки белков поверхности клеток из композиции модифицированных клеток и оценки способа получения композиции генетически модифицированных клеток.
EA202190693A 2018-09-11 2019-09-11 Способы анализа масс-спектрометрии композиций модифицированных клеток EA202190693A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862729985P 2018-09-11 2018-09-11
PCT/US2019/050681 WO2020056047A1 (en) 2018-09-11 2019-09-11 Methods for mass spectrometry analysis of engineered cell compositions

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EA202190693A1 true EA202190693A1 (ru) 2021-07-27

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US (1) US20220050114A1 (ru)
EP (1) EP3850366A1 (ru)
JP (1) JP7504891B2 (ru)
KR (1) KR20210081341A (ru)
CN (1) CN113167796A (ru)
AU (1) AU2019339464A1 (ru)
BR (1) BR112021004261A2 (ru)
CA (1) CA3111789A1 (ru)
EA (1) EA202190693A1 (ru)
IL (1) IL281325A (ru)
MA (1) MA53612A (ru)
MX (1) MX2021002574A (ru)
SG (1) SG11202102108QA (ru)
WO (1) WO2020056047A1 (ru)

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EP4277917A4 (en) * 2021-01-14 2024-06-19 Biocatalyst LLC COMPOSITIONS AND PROCESSES FOR PRODUCING PEPTIDES

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WO2018027197A1 (en) 2016-08-04 2018-02-08 Memorial Sloan-Kettering Cancer Center Cancer antigen targets and uses thereof
JP7228522B2 (ja) 2017-02-27 2023-02-24 ジュノー セラピューティクス インコーポレイテッド 細胞療法における投薬に関する組成物、製造物品、および方法

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