JP2017523424A5 - - Google Patents

Download PDF

Info

Publication number
JP2017523424A5
JP2017523424A5 JP2017505233A JP2017505233A JP2017523424A5 JP 2017523424 A5 JP2017523424 A5 JP 2017523424A5 JP 2017505233 A JP2017505233 A JP 2017505233A JP 2017505233 A JP2017505233 A JP 2017505233A JP 2017523424 A5 JP2017523424 A5 JP 2017523424A5
Authority
JP
Japan
Prior art keywords
detection device
nanopores
nanopore
lipid
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017505233A
Other languages
English (en)
Japanese (ja)
Other versions
JP6601852B2 (ja
JP2017523424A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2015/042680 external-priority patent/WO2016019030A1/en
Publication of JP2017523424A publication Critical patent/JP2017523424A/ja
Publication of JP2017523424A5 publication Critical patent/JP2017523424A5/ja
Application granted granted Critical
Publication of JP6601852B2 publication Critical patent/JP6601852B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2017505233A 2014-07-31 2015-07-29 ハイブリッドナノポアセンサ Active JP6601852B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462031762P 2014-07-31 2014-07-31
US62/031,762 2014-07-31
US201562157749P 2015-05-06 2015-05-06
US62/157,749 2015-05-06
PCT/US2015/042680 WO2016019030A1 (en) 2014-07-31 2015-07-29 Hybrid nanopore sensors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019182334A Division JP7010911B2 (ja) 2014-07-31 2019-10-02 ハイブリッドナノポアセンサ

Publications (3)

Publication Number Publication Date
JP2017523424A JP2017523424A (ja) 2017-08-17
JP2017523424A5 true JP2017523424A5 (https=) 2018-09-06
JP6601852B2 JP6601852B2 (ja) 2019-11-06

Family

ID=53794530

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2017505233A Active JP6601852B2 (ja) 2014-07-31 2015-07-29 ハイブリッドナノポアセンサ
JP2019182334A Active JP7010911B2 (ja) 2014-07-31 2019-10-02 ハイブリッドナノポアセンサ
JP2022003315A Active JP7320326B2 (ja) 2014-07-31 2022-01-12 ハイブリッドナノポアセンサ
JP2023118149A Active JP7586977B2 (ja) 2014-07-31 2023-07-20 ハイブリッドナノポアセンサ

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2019182334A Active JP7010911B2 (ja) 2014-07-31 2019-10-02 ハイブリッドナノポアセンサ
JP2022003315A Active JP7320326B2 (ja) 2014-07-31 2022-01-12 ハイブリッドナノポアセンサ
JP2023118149A Active JP7586977B2 (ja) 2014-07-31 2023-07-20 ハイブリッドナノポアセンサ

Country Status (10)

Country Link
US (4) US10519499B2 (https=)
EP (4) EP4379373B1 (https=)
JP (4) JP6601852B2 (https=)
CN (3) CN113759105A (https=)
AU (4) AU2015296551B2 (https=)
CA (2) CA2956794A1 (https=)
DK (1) DK3702780T3 (https=)
ES (2) ES2984002T3 (https=)
SG (2) SG10201809900PA (https=)
WO (1) WO2016019030A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110914291B (zh) * 2017-07-17 2024-10-29 哈佛大学校董委员会 用于分子表征的纳米孔匹配的蛋白质穿梭物
CN108226249B (zh) * 2018-01-09 2021-02-26 深圳市梅丽纳米孔科技有限公司 一次性纳米孔生物传感器及其制作方法
AU2019222673B2 (en) * 2018-02-16 2022-01-20 Illumina, Inc. Device for sequencing
CN121472373A (zh) 2018-05-22 2026-02-06 安序源有限公司 用于核酸测序的方法、系统和组合物
KR102127111B1 (ko) * 2019-01-31 2020-06-26 경희대학교 산학협력단 나노포어의 제조 방법 및 이를 통해 제조된 나노포어 구조체
JP2022529623A (ja) * 2019-04-09 2022-06-23 オックスフォード ナノポール テクノロジーズ ピーエルシー 細孔
CN110292916B (zh) * 2019-06-26 2020-11-03 中国科学院过程工程研究所 一种磷脂纳米盘层析介质及其制备方法和应用
WO2021021944A1 (en) * 2019-07-31 2021-02-04 Axbio Inc. Systems and methods for assessing a target molecule
CN110628599A (zh) * 2019-10-19 2019-12-31 上海新微技术研发中心有限公司 拉曼光谱法生物分子测序系统
JP7365022B2 (ja) * 2019-10-28 2023-10-19 日本電信電話株式会社 生体分子の支持体とその製造方法
JP7676380B2 (ja) * 2019-10-30 2025-05-14 エフ. ホフマン-ラ ロシュ アーゲー 生物学的ナノポアのアセンブリのための方法及び組成物
WO2023055752A2 (en) 2021-09-28 2023-04-06 Axbio Inc. Methods for processing a nucleic acid sample and compositions thereof
IL320502A (en) 2022-10-28 2025-06-01 Univ Groningen Nanopore-based protein efflux
JP2026511769A (ja) * 2023-03-30 2026-04-14 エフ. ホフマン-ラ ロシュ アーゲー 標的分子脂質二重層の相互作用の調節
CN116622754A (zh) * 2023-05-31 2023-08-22 南开大学 一种定点标记的跨膜蛋白纳米盘及其制备方法和应用
WO2025227058A1 (en) * 2024-04-26 2025-10-30 Roche Sequencing Solutions, Inc. Detergent-free nanopore delivery
GB202414708D0 (en) 2024-10-07 2024-11-20 Ucl Business Ltd Nanodiscs as a delivery vehicle for insertion of nanopores into sensor membranes

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795782A (en) 1995-03-17 1998-08-18 President & Fellows Of Harvard College Characterization of individual polymer molecules based on monomer-interface interactions
AUPN366995A0 (en) * 1995-06-20 1995-07-13 Australian Membrane And Biotechnology Research Institute Self-assembly of bilayer membrane sensors
US7083958B2 (en) * 2000-11-20 2006-08-01 The Board Of Trustees Of The University Of Illinois Membrane scaffold proteins
US7592008B2 (en) 2000-11-20 2009-09-22 The Board Of Trustees Of The University Of Illinois, A Body Corporate And Politic Of The State Of Illinois Membrane scaffold proteins
DK1345959T3 (da) * 2000-11-20 2011-09-05 Univ Illinois Membranscaffoldproteiner
US20050023156A1 (en) * 2003-07-30 2005-02-03 Ramsey J. Michael Nanostructured material transport devices and their fabrication by application of molecular coatings to nanoscale channels
GB0505971D0 (en) 2005-03-23 2005-04-27 Isis Innovation Delivery of molecules to a lipid bilayer
US20060231419A1 (en) * 2005-04-15 2006-10-19 Barth Philip W Molecular resonant tunneling sensor and methods of fabricating and using the same
US7638034B2 (en) * 2006-09-21 2009-12-29 Los Alamos National Security, Llc Electrochemical detection of single molecules using abiotic nanopores having electrically tunable dimensions
CN1932039B (zh) * 2006-09-21 2010-06-16 上海交通大学 外切酶-纳米孔的单分子核酸测序方法
WO2008102120A1 (en) 2007-02-20 2008-08-28 Oxford Nanopore Technologies Limited Lipid bilayer sensor system
US20080254995A1 (en) * 2007-02-27 2008-10-16 Drexel University Nanopore arrays and sequencing devices and methods thereof
WO2008124706A2 (en) 2007-04-06 2008-10-16 Arizona Board Of Regents Acting For And On Behalf Of Arizona State University Devices and methods for target molecule characterization
US20110059549A1 (en) * 2007-05-09 2011-03-10 Coleman Matthew A Methods and systems for producing nanolipoprotein particles
CN101848757B (zh) 2007-07-13 2013-12-04 里兰斯坦福初级大学理事会 用于改进的生物测定法的使用电场的方法和设备
GB0808856D0 (en) 2008-05-15 2008-06-25 Univ Warwick Fabricated nanopores and micropores for chemical and biochemical analysis
WO2010004265A1 (en) 2008-07-07 2010-01-14 Oxford Nanopore Technologies Limited Enzyme-pore constructs
US20100099198A1 (en) * 2008-07-11 2010-04-22 Board Of Regents, The University Of Texas System Apparatus and system for pattern recognition sensing for biomolecules
CA3092369C (en) 2008-09-22 2025-09-23 University Of Washington MSP NANOPORES AND ASSOCIATED PROCESSES
JP2012507565A (ja) * 2008-10-30 2012-03-29 グオ・ペイシュエン Dnaのシークエンシング及び他の用途のための、膜に組み込まれたウイルスdnaパッケージングモータタンパク質コネクタバイオセンサ
US8986928B2 (en) * 2009-04-10 2015-03-24 Pacific Biosciences Of California, Inc. Nanopore sequencing devices and methods
US20140335513A9 (en) * 2009-09-30 2014-11-13 Quantapore, Inc. Hybrid nanopore device with optical detection and methods of using same
CA2995178C (en) * 2010-02-08 2023-09-12 Genia Technologies, Inc. Method and system for forming a nanopore in a lipid bilayer
CA3116307C (en) 2010-02-23 2023-10-17 University Of Washington Artificial mycolic acid membranes
US8652779B2 (en) 2010-04-09 2014-02-18 Pacific Biosciences Of California, Inc. Nanopore sequencing using charge blockade labels
US8828211B2 (en) * 2010-06-08 2014-09-09 President And Fellows Of Harvard College Nanopore device with graphene supported artificial lipid membrane
CA2805247C (en) 2010-07-14 2021-08-10 The Curators Of The University Of Missouri Nanopore-facilitated single molecule detection of nucleic acids
WO2012060882A2 (en) 2010-11-02 2012-05-10 Molecular Sensing, Inc. Interferometric detection using nanoparticles
EP2652153B1 (en) * 2010-12-17 2017-07-05 The Trustees of Columbia University in the City of New York Dna sequencing by synthesis using modified nucleotides and nanopore detection
WO2012088339A2 (en) 2010-12-22 2012-06-28 Genia Technologies, Inc. Nanopore-based single dna molecule characterization using speed bumps
WO2012116161A1 (en) * 2011-02-23 2012-08-30 The Trustees Of Columbia University In The City Of New York Systems and methods for single-molecule detection using nanopores
CN103842519B (zh) * 2011-04-04 2018-02-06 哈佛大学校长及研究员协会 通过局部电位测量进行的纳米孔感测
EP3385992B1 (en) 2011-07-27 2024-09-04 The Board of Trustees of the University of Illinois Nanopore sensors for biomolecular characterization
JP6226869B2 (ja) 2011-10-21 2017-11-08 オックスフォード ナノポール テクノロジーズ リミテッド 酵素法
CA2856163C (en) 2011-10-28 2019-05-07 Illumina, Inc. Microarray fabrication system and method
EP3540077B1 (en) * 2012-02-16 2021-01-27 Genia Technologies, Inc. Methods for creating bilayers for use with nanopore sensors
CA2864824C (en) 2012-02-16 2020-06-16 The Regents Of The University Of California Nanopore sensor for enzyme-mediated protein translocation
CN102621214B (zh) * 2012-03-13 2014-10-29 美国哈佛大学 一种基于固态纳米孔对核酸分子进行减速及单分子捕获的方法
US20130302901A1 (en) 2012-04-04 2013-11-14 Stuart Lindsay Electrodes for Sensing Chemical Composition
EP2745834B1 (en) 2012-12-18 2016-09-28 Jens Frauenfeld Salipro particles
WO2015002813A1 (en) 2013-07-01 2015-01-08 Illumina, Inc. Catalyst-free surface functionalization and polymer grafting

Similar Documents

Publication Publication Date Title
JP2017523424A5 (https=)
US12297497B2 (en) Methods for forming lipid bilayers on biochips
JP6063062B2 (ja) ナノポアアレイ
JP5858931B2 (ja) ナノ細孔内の分子を操作するためのシステムおよび方法
CA2977798C (en) Nanopore-based sequencing with varying voltage stimulus
JP6302547B2 (ja) ナノポアセルアレイにおける非ファラデー性容量結合測定
JP2018075021A5 (https=)
FI2539465T3 (fi) Analyyttien sekvensointi nanohuokosten avulla
JP2018510329A5 (https=)
JP2015525077A5 (https=)
EP4379373A3 (en) Nucleic acid sequencing with hybrid nanopore sensors
JP2017536103A5 (https=)
KR20100114038A (ko) 양쪽 친매성 분자들 층의 형성
JP2019516952A (ja) 二重層形成の電気的促進
JP2019522196A (ja) 二重層形成のための浸透性不均衡法
JP2015523095A5 (https=)
JP2016126003A (ja) 検体検出方法および検体検出装置
CN104704130A (zh) 借助隧道电流分析用于核酸-测序的装置
US20030062657A1 (en) On-chip membrane maker
CN103940864B (zh) 双管式单分子微流装置
JP7239923B2 (ja) 測定装置
JP2004251900A5 (https=)
Busch et al. Focus ion beam based nanofluidic system for biomolecule characterization
Ghanim et al. Design of a Low-Cost DNA Biochip Using Copper Electrode.