DK3702780T3 - Hybride nanoporesensorer - Google Patents
Hybride nanoporesensorer Download PDFInfo
- Publication number
- DK3702780T3 DK3702780T3 DK20160143.2T DK20160143T DK3702780T3 DK 3702780 T3 DK3702780 T3 DK 3702780T3 DK 20160143 T DK20160143 T DK 20160143T DK 3702780 T3 DK3702780 T3 DK 3702780T3
- Authority
- DK
- Denmark
- Prior art keywords
- nanopore sensors
- hybrid nanopore
- hybrid
- sensors
- nanopore
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
- G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44782—Apparatus specially adapted therefor of a plurality of samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44791—Microapparatus
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Electrochemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Nanotechnology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Dispersion Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462031762P | 2014-07-31 | 2014-07-31 | |
| US201562157749P | 2015-05-06 | 2015-05-06 | |
| EP15748142.5A EP3175237B1 (en) | 2014-07-31 | 2015-07-29 | Hybrid nanopore sensors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3702780T3 true DK3702780T3 (da) | 2022-05-23 |
Family
ID=53794530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK20160143.2T DK3702780T3 (da) | 2014-07-31 | 2015-07-29 | Hybride nanoporesensorer |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US10519499B2 (https=) |
| EP (4) | EP3982121B1 (https=) |
| JP (4) | JP6601852B2 (https=) |
| CN (3) | CN106796214B (https=) |
| AU (4) | AU2015296551B2 (https=) |
| CA (2) | CA3163156C (https=) |
| DK (1) | DK3702780T3 (https=) |
| ES (2) | ES2912963T3 (https=) |
| SG (2) | SG11201700745XA (https=) |
| WO (1) | WO2016019030A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3655423B1 (en) * | 2017-07-17 | 2023-12-20 | President and Fellows of Harvard College | Nanopore-matched protein shuttle for molecular characterization |
| CN108226249B (zh) * | 2018-01-09 | 2021-02-26 | 深圳市梅丽纳米孔科技有限公司 | 一次性纳米孔生物传感器及其制作方法 |
| NZ759671A (en) * | 2018-02-16 | 2022-07-01 | Illumina Inc | Device for sequencing |
| CN112534063A (zh) | 2018-05-22 | 2021-03-19 | 安序源有限公司 | 用于核酸测序的方法、系统和组合物 |
| KR102127111B1 (ko) * | 2019-01-31 | 2020-06-26 | 경희대학교 산학협력단 | 나노포어의 제조 방법 및 이를 통해 제조된 나노포어 구조체 |
| JP2022529623A (ja) * | 2019-04-09 | 2022-06-23 | オックスフォード ナノポール テクノロジーズ ピーエルシー | 細孔 |
| CN110292916B (zh) * | 2019-06-26 | 2020-11-03 | 中国科学院过程工程研究所 | 一种磷脂纳米盘层析介质及其制备方法和应用 |
| EP4003382A4 (en) * | 2019-07-31 | 2023-10-11 | Axbio Inc. | SYSTEMS AND METHODS FOR EVALUATION OF A TARGET MOLECULE |
| CN110628599A (zh) * | 2019-10-19 | 2019-12-31 | 上海新微技术研发中心有限公司 | 拉曼光谱法生物分子测序系统 |
| JP7365022B2 (ja) * | 2019-10-28 | 2023-10-19 | 日本電信電話株式会社 | 生体分子の支持体とその製造方法 |
| CN114630891B (zh) * | 2019-10-30 | 2025-06-10 | 豪夫迈·罗氏有限公司 | 用于生物纳米孔的组装的方法和组合物 |
| CN118318049A (zh) | 2021-09-28 | 2024-07-09 | 安序源有限公司 | 用于处理核酸样品的方法以及核酸样品的组合物 |
| KR20250116014A (ko) | 2022-10-28 | 2025-07-31 | 리엑스유니버시테이트 그로닝겐 | 나노기공-기반 단백질 분석 |
| AU2024246785A1 (en) * | 2023-03-30 | 2025-09-11 | F. Hoffmann-La Roche Ag | Modulation of target molecule-lipid bilayer interactions |
| CN116622754A (zh) * | 2023-05-31 | 2023-08-22 | 南开大学 | 一种定点标记的跨膜蛋白纳米盘及其制备方法和应用 |
| WO2025227058A1 (en) * | 2024-04-26 | 2025-10-30 | Roche Sequencing Solutions, Inc. | Detergent-free nanopore delivery |
| GB202414708D0 (en) | 2024-10-07 | 2024-11-20 | Ucl Business Ltd | Nanodiscs as a delivery vehicle for insertion of nanopores into sensor membranes |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5795782A (en) | 1995-03-17 | 1998-08-18 | President & Fellows Of Harvard College | Characterization of individual polymer molecules based on monomer-interface interactions |
| AUPN366995A0 (en) * | 1995-06-20 | 1995-07-13 | Australian Membrane And Biotechnology Research Institute | Self-assembly of bilayer membrane sensors |
| US7592008B2 (en) | 2000-11-20 | 2009-09-22 | The Board Of Trustees Of The University Of Illinois, A Body Corporate And Politic Of The State Of Illinois | Membrane scaffold proteins |
| DK1345959T3 (da) * | 2000-11-20 | 2011-09-05 | Univ Illinois | Membranscaffoldproteiner |
| US7083958B2 (en) * | 2000-11-20 | 2006-08-01 | The Board Of Trustees Of The University Of Illinois | Membrane scaffold proteins |
| US20050023156A1 (en) * | 2003-07-30 | 2005-02-03 | Ramsey J. Michael | Nanostructured material transport devices and their fabrication by application of molecular coatings to nanoscale channels |
| GB0505971D0 (en) | 2005-03-23 | 2005-04-27 | Isis Innovation | Delivery of molecules to a lipid bilayer |
| US20060231419A1 (en) * | 2005-04-15 | 2006-10-19 | Barth Philip W | Molecular resonant tunneling sensor and methods of fabricating and using the same |
| US7638034B2 (en) * | 2006-09-21 | 2009-12-29 | Los Alamos National Security, Llc | Electrochemical detection of single molecules using abiotic nanopores having electrically tunable dimensions |
| CN1932039B (zh) * | 2006-09-21 | 2010-06-16 | 上海交通大学 | 外切酶-纳米孔的单分子核酸测序方法 |
| US20110121840A1 (en) | 2007-02-20 | 2011-05-26 | Gurdial Singh Sanghera | Lipid Bilayer Sensor System |
| US20080254995A1 (en) * | 2007-02-27 | 2008-10-16 | Drexel University | Nanopore arrays and sequencing devices and methods thereof |
| WO2008124706A2 (en) * | 2007-04-06 | 2008-10-16 | Arizona Board Of Regents Acting For And On Behalf Of Arizona State University | Devices and methods for target molecule characterization |
| WO2008141230A1 (en) * | 2007-05-09 | 2008-11-20 | Lawrence Livermore National Security, Llc | Methods and systems for monitoring production of a target protein in a nanolipoprotein particle |
| BRPI0813718A2 (pt) | 2007-07-13 | 2014-12-30 | Univ Leland Stanford Junior | Método e aparelho que utilizam um campo elétrico para ensaios biológicos aperfeiçoados |
| GB0808856D0 (en) * | 2008-05-15 | 2008-06-25 | Univ Warwick | Fabricated nanopores and micropores for chemical and biochemical analysis |
| US20110229877A1 (en) | 2008-07-07 | 2011-09-22 | Oxford Nanopore Technologies Limited | Enzyme-pore constructs |
| US20100099198A1 (en) * | 2008-07-11 | 2010-04-22 | Board Of Regents, The University Of Texas System | Apparatus and system for pattern recognition sensing for biomolecules |
| CA2774710C (en) | 2008-09-22 | 2016-08-02 | University Of Washington | Msp nanopores and related methods |
| JP2012507565A (ja) * | 2008-10-30 | 2012-03-29 | グオ・ペイシュエン | Ｄｎａのシークエンシング及び他の用途のための、膜に組み込まれたウイルスｄｎａパッケージングモータタンパク質コネクタバイオセンサ |
| US8986928B2 (en) * | 2009-04-10 | 2015-03-24 | Pacific Biosciences Of California, Inc. | Nanopore sequencing devices and methods |
| US20140335513A9 (en) * | 2009-09-30 | 2014-11-13 | Quantapore, Inc. | Hybrid nanopore device with optical detection and methods of using same |
| WO2011097028A1 (en) * | 2010-02-08 | 2011-08-11 | Genia Technologies, Inc. | Systems and methods for manipulating a molecule in a nanopore |
| CN102834716B (zh) | 2010-02-23 | 2016-03-30 | 华盛顿大学 | 人工分枝菌酸膜 |
| US8652779B2 (en) | 2010-04-09 | 2014-02-18 | Pacific Biosciences Of California, Inc. | Nanopore sequencing using charge blockade labels |
| US8828211B2 (en) * | 2010-06-08 | 2014-09-09 | President And Fellows Of Harvard College | Nanopore device with graphene supported artificial lipid membrane |
| WO2012009578A2 (en) * | 2010-07-14 | 2012-01-19 | The Curators Of The University Of Missouri | Nanopore-facilitated single molecule detection of nucleic acids |
| WO2012060882A2 (en) | 2010-11-02 | 2012-05-10 | Molecular Sensing, Inc. | Interferometric detection using nanoparticles |
| WO2012083249A2 (en) * | 2010-12-17 | 2012-06-21 | The Trustees Of Columbia University In The City Of New York | Dna sequencing by synthesis using modified nucleotides and nanopore detection |
| GB2500360B (en) * | 2010-12-22 | 2019-10-23 | Genia Tech Inc | Nanopore-based single DNA molecule characterization, identification and isolation using speed bumps |
| EP2678669A1 (en) * | 2011-02-23 | 2014-01-01 | The Trustees of Columbia University in the City of New York | Systems and methods for single-molecule detection using nanopores |
| CN108051578B (zh) * | 2011-04-04 | 2020-07-24 | 哈佛大学校长及研究员协会 | 通过局部电位测量进行的纳米孔感测 |
| KR102023754B1 (ko) | 2011-07-27 | 2019-09-20 | 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 | 생체분자 특성규명용 나노포어 센서 |
| CN104039979B (zh) | 2011-10-21 | 2016-08-24 | 牛津纳米孔技术公司 | 使用孔和Hel308解旋酶表征目标多核苷酸的酶方法 |
| EP3305400A3 (en) | 2011-10-28 | 2018-06-06 | Illumina, Inc. | Microarray fabrication system and method |
| CN104254619B (zh) | 2012-02-16 | 2018-08-24 | 吉尼亚科技公司 | 产生用于纳米孔传感器的双层的方法 |
| WO2013123379A2 (en) | 2012-02-16 | 2013-08-22 | The Regents Of The University Of California | Nanopore sensor for enzyme-mediated protein translocation |
| CN102621214B (zh) * | 2012-03-13 | 2014-10-29 | 美国哈佛大学 | 一种基于固态纳米孔对核酸分子进行减速及单分子捕获的方法 |
| US20130302901A1 (en) * | 2012-04-04 | 2013-11-14 | Stuart Lindsay | Electrodes for Sensing Chemical Composition |
| EP2745834B1 (en) * | 2012-12-18 | 2016-09-28 | Jens Frauenfeld | Salipro particles |
| DK3017065T3 (en) | 2013-07-01 | 2018-11-26 | Illumina Inc | Catalyst-free Surface functionalization and polymer grafting |
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2015
- 2015-07-29 CA CA3163156A patent/CA3163156C/en active Active
- 2015-07-29 EP EP21212383.0A patent/EP3982121B1/en active Active
- 2015-07-29 EP EP15748142.5A patent/EP3175237B1/en active Active
- 2015-07-29 SG SG11201700745XA patent/SG11201700745XA/en unknown
- 2015-07-29 AU AU2015296551A patent/AU2015296551B2/en active Active
- 2015-07-29 CN CN201580047480.XA patent/CN106796214B/zh active Active
- 2015-07-29 CN CN202111088301.0A patent/CN113759105A/zh active Pending
- 2015-07-29 SG SG10201809900PA patent/SG10201809900PA/en unknown
- 2015-07-29 CN CN201911345586.4A patent/CN110954686B/zh active Active
- 2015-07-29 EP EP24167857.2A patent/EP4379373B1/en active Active
- 2015-07-29 DK DK20160143.2T patent/DK3702780T3/da active
- 2015-07-29 EP EP20160143.2A patent/EP3702780B1/en active Active
- 2015-07-29 US US15/522,987 patent/US10519499B2/en active Active
- 2015-07-29 CA CA2956794A patent/CA2956794A1/en active Pending
- 2015-07-29 ES ES20160143T patent/ES2912963T3/es active Active
- 2015-07-29 ES ES21212383T patent/ES2984002T3/es active Active
- 2015-07-29 JP JP2017505233A patent/JP6601852B2/ja active Active
- 2015-07-29 WO PCT/US2015/042680 patent/WO2016019030A1/en not_active Ceased
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2019
- 2019-10-02 JP JP2019182334A patent/JP7010911B2/ja active Active
- 2019-12-09 US US16/707,554 patent/US10961576B2/en active Active
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2021
- 2021-03-01 US US17/188,193 patent/US11732301B2/en active Active
- 2021-09-06 AU AU2021229125A patent/AU2021229125B2/en active Active
- 2021-09-06 AU AU2021229126A patent/AU2021229126A1/en not_active Withdrawn
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2022
- 2022-01-12 JP JP2022003315A patent/JP7320326B2/ja active Active
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2023
- 2023-06-29 US US18/344,035 patent/US20240011089A1/en active Pending
- 2023-07-20 JP JP2023118149A patent/JP7586977B2/ja active Active
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2024
- 2024-12-17 AU AU2024278529A patent/AU2024278529A1/en active Pending
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