JP2017521389A5 - - Google Patents
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- Publication number
- JP2017521389A5 JP2017521389A5 JP2016572703A JP2016572703A JP2017521389A5 JP 2017521389 A5 JP2017521389 A5 JP 2017521389A5 JP 2016572703 A JP2016572703 A JP 2016572703A JP 2016572703 A JP2016572703 A JP 2016572703A JP 2017521389 A5 JP2017521389 A5 JP 2017521389A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- tnfr
- fusion protein
- chromatography column
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1919MU2014 | 2014-06-13 | ||
| IN1919/MUM/2014 | 2014-06-13 | ||
| PCT/IB2015/054494 WO2015189832A1 (en) | 2014-06-13 | 2015-06-13 | Process for the purification of tnfr:fc fusion protein |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017521389A JP2017521389A (ja) | 2017-08-03 |
| JP2017521389A5 true JP2017521389A5 (enExample) | 2018-07-19 |
| JP6747985B2 JP6747985B2 (ja) | 2020-08-26 |
Family
ID=53524922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016572703A Expired - Fee Related JP6747985B2 (ja) | 2014-06-13 | 2015-06-13 | ＴＮＦＲ：Ｆｃ融合タンパク質の精製方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10556942B2 (enExample) |
| EP (1) | EP3155009A1 (enExample) |
| JP (1) | JP6747985B2 (enExample) |
| CN (1) | CN106536565A (enExample) |
| AU (1) | AU2015273049B2 (enExample) |
| BR (1) | BR112016029157A8 (enExample) |
| CA (1) | CA2951766A1 (enExample) |
| MA (1) | MA40232A (enExample) |
| MX (1) | MX2016016318A (enExample) |
| PH (1) | PH12016502482A1 (enExample) |
| RU (1) | RU2698654C2 (enExample) |
| WO (1) | WO2015189832A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11566082B2 (en) | 2014-11-17 | 2023-01-31 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| US20180079796A1 (en) * | 2015-03-13 | 2018-03-22 | Samsung Bioepis Co., Ltd. | Anti-tnf-alpha polypeptide composition and use thereof |
| JP7031934B2 (ja) | 2016-05-11 | 2022-03-08 | サイティバ・バイオプロセス・アールアンドディ・アクチボラグ | 分離マトリックス |
| US10730908B2 (en) | 2016-05-11 | 2020-08-04 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| WO2017194592A1 (en) | 2016-05-11 | 2017-11-16 | Ge Healthcare Bioprocess R&D Ab | Method of storing a separation matrix |
| EP3455241B1 (en) | 2016-05-11 | 2022-02-23 | Cytiva BioProcess R&D AB | Method of cleaning and/or sanitizing a separation matrix |
| US10703774B2 (en) | 2016-09-30 | 2020-07-07 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| US10654887B2 (en) | 2016-05-11 | 2020-05-19 | Ge Healthcare Bio-Process R&D Ab | Separation matrix |
| JP7122974B2 (ja) | 2016-05-11 | 2022-08-22 | サイティバ・バイオプロセス・アールアンドディ・アクチボラグ | 変異免疫グロブリン結合ポリペプチド |
| US12448411B2 (en) | 2016-09-30 | 2025-10-21 | Cytiva Bioprocess R&D Ab | Separation method |
| MY199833A (en) * | 2017-08-17 | 2023-11-24 | Just Evotec Biologics Inc | Method of purifying glycosylated protein from host cell galectins and other contaminants |
| EP3676281A1 (en) * | 2017-08-30 | 2020-07-08 | Ares Trading S.A. | Method for purifying proteins |
| US11952399B2 (en) * | 2018-12-18 | 2024-04-09 | Amgen Inc. | Methods for purifying proteins |
| MX2021008983A (es) * | 2019-01-30 | 2021-09-08 | Amgen Inc | Atributos de aflibercept y metodos de caracterizacion y modificacion de los mismos. |
| KR102286892B1 (ko) * | 2019-07-08 | 2021-08-06 | 삼천당제약주식회사 | 안과용 단백질 제제의 정제방법 |
| CN112876567A (zh) * | 2019-11-29 | 2021-06-01 | 广东菲鹏制药股份有限公司 | Fc融合蛋白及其纯化方法 |
| WO2021181417A1 (en) * | 2020-03-11 | 2021-09-16 | Dr. Reddy's Laboratories Limited | METHOD OF PURIFYING AN Fc-FUSION PROTEIN |
| CN113563469A (zh) * | 2020-04-28 | 2021-10-29 | 江苏中新医药有限公司 | 高回收率纯化阿达木单抗的方法 |
| WO2022234412A1 (en) * | 2021-05-03 | 2022-11-10 | Lupin Limited | A process for purification of fc-fusion proteins |
| EP4408857A4 (en) * | 2021-09-28 | 2025-11-05 | Kashiv Biosciences Llc | IMPROVED PROCESS FOR PURIFICATION OF FUSION PROTEIN |
| CA3233419A1 (en) * | 2021-09-28 | 2023-04-06 | Kashiv Biosciences, Llc | An improved process for purification of protein |
| AU2022354256A1 (en) * | 2021-09-28 | 2024-04-11 | Kashiv Biosciences, Llc | An improved process for purification of fusion protein |
| EP4421089A4 (en) * | 2021-10-19 | 2026-01-07 | Alteogen Inc | METHOD FOR PURIFYING A FUSION PROTEIN HAVING AN IGG FC DOMAIN |
| US20250026784A1 (en) * | 2021-11-29 | 2025-01-23 | Tosoh Corporation | Separation method of antibody |
| CN119060168A (zh) * | 2024-09-26 | 2024-12-03 | 广东丸美生物技术股份有限公司 | 一种具有低电导率的重组胶原蛋白溶液及其制备方法和应用 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2021284C1 (ru) * | 1991-05-30 | 1994-10-15 | Всесоюзный научно-исследовательский институт технологии кровезаменителей и гормональных препаратов | Способ очистки клинических фракций декстрана |
| US7294481B1 (en) | 1999-01-05 | 2007-11-13 | Immunex Corporation | Method for producing recombinant proteins |
| CA2476934C (en) | 2002-02-27 | 2009-06-16 | Immunex Corporation | Stabilized tnfr-fc composition comprising arginine |
| WO2004076485A1 (en) | 2003-02-28 | 2004-09-10 | Lonza Biologics Plc. | Antibody purification by protein a and ion exchange chromatography |
| US8263750B2 (en) * | 2006-03-16 | 2012-09-11 | Amgen Inc. | Method for purifying a protein using protein-A affinity chromatography using an intermediate wash step |
| JP2010501623A (ja) * | 2006-08-28 | 2010-01-21 | アレス トレーディング ソシエテ アノニム | Ｆｃ含有タンパク質の精製法 |
| JP2010501622A (ja) * | 2006-08-28 | 2010-01-21 | アレス トレーディング ソシエテ アノニム | Ｆｃ−融合タンパク質の精製法 |
| EP2203465A1 (en) * | 2007-10-22 | 2010-07-07 | Merck Serono S.A. | Method for purifying an fc-containing protein |
| JP2011514895A (ja) * | 2008-02-29 | 2011-05-12 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 精製免疫グロブリン融合タンパク質およびその精製方法 |
| CN105646643A (zh) * | 2008-10-29 | 2016-06-08 | 阿布林克斯公司 | 单域抗原结合性分子的纯化方法 |
| EP2526114B1 (de) * | 2010-01-22 | 2014-06-18 | Boehringer Ingelheim International GmbH | Chromatographisches verfahren zur aufreinigung von fc enthaltenden proteinen |
| EP2723759A4 (en) * | 2011-06-24 | 2015-01-28 | Reddys Lab Ltd Dr | PURIFICATION OF CHIMERIC PROTEIN |
| JP6280499B2 (ja) * | 2011-07-08 | 2018-02-14 | メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． | Ｆｃ融合タンパク質の精製方法 |
| ES2651483T3 (es) * | 2011-08-17 | 2018-01-26 | Ares Trading S.A. | Método para preparar la forma activa de la proteína de fusión TNRF-Fc |
| US9249182B2 (en) | 2012-05-24 | 2016-02-02 | Abbvie, Inc. | Purification of antibodies using hydrophobic interaction chromatography |
| KR102250937B1 (ko) * | 2012-09-11 | 2021-05-12 | 코히러스 바이오사이언시즈, 인코포레이티드 | 고순도 및 탁월한 수율의 정확하게 폴딩된 에타너셉트 |
| CN102911250B (zh) | 2012-09-29 | 2014-04-16 | 浙江海正药业股份有限公司 | 酸性重组蛋白药物的纯化方法 |
| WO2014078627A1 (en) * | 2012-11-19 | 2014-05-22 | Merck Sharp & Dohme Corp. | Liquid formulations for tnfr:fc fusion proteins |
| PL3395423T3 (pl) * | 2013-03-14 | 2024-03-18 | Amgen Inc. | Usuwanie wypłukanych ligandów do oczyszczania na zasadzie powinowactwa |
| US8946395B1 (en) * | 2013-10-18 | 2015-02-03 | Abbvie Inc. | Purification of proteins using hydrophobic interaction chromatography |
-
2015
- 2015-06-13 WO PCT/IB2015/054494 patent/WO2015189832A1/en not_active Ceased
- 2015-06-13 BR BR112016029157A patent/BR112016029157A8/pt not_active Application Discontinuation
- 2015-06-13 MX MX2016016318A patent/MX2016016318A/es unknown
- 2015-06-13 CN CN201580038801.XA patent/CN106536565A/zh active Pending
- 2015-06-13 MA MA040232A patent/MA40232A/fr unknown
- 2015-06-13 US US15/318,489 patent/US10556942B2/en active Active
- 2015-06-13 CA CA2951766A patent/CA2951766A1/en not_active Abandoned
- 2015-06-13 JP JP2016572703A patent/JP6747985B2/ja not_active Expired - Fee Related
- 2015-06-13 EP EP15734731.1A patent/EP3155009A1/en not_active Withdrawn
- 2015-06-13 RU RU2017100005A patent/RU2698654C2/ru active
- 2015-06-13 AU AU2015273049A patent/AU2015273049B2/en not_active Ceased
-
2016
- 2016-12-13 PH PH12016502482A patent/PH12016502482A1/en unknown
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