JP2017521389A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017521389A5 JP2017521389A5 JP2016572703A JP2016572703A JP2017521389A5 JP 2017521389 A5 JP2017521389 A5 JP 2017521389A5 JP 2016572703 A JP2016572703 A JP 2016572703A JP 2016572703 A JP2016572703 A JP 2016572703A JP 2017521389 A5 JP2017521389 A5 JP 2017521389A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- tnfr
- fusion protein
- chromatography column
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1919MU2014 | 2014-06-13 | ||
| IN1919/MUM/2014 | 2014-06-13 | ||
| PCT/IB2015/054494 WO2015189832A1 (en) | 2014-06-13 | 2015-06-13 | Process for the purification of tnfr:fc fusion protein |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017521389A JP2017521389A (ja) | 2017-08-03 |
| JP2017521389A5 true JP2017521389A5 (enExample) | 2018-07-19 |
| JP6747985B2 JP6747985B2 (ja) | 2020-08-26 |
Family
ID=53524922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016572703A Expired - Fee Related JP6747985B2 (ja) | 2014-06-13 | 2015-06-13 | ＴＮＦＲ：Ｆｃ融合タンパク質の精製方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10556942B2 (enExample) |
| EP (1) | EP3155009A1 (enExample) |
| JP (1) | JP6747985B2 (enExample) |
| CN (1) | CN106536565A (enExample) |
| AU (1) | AU2015273049B2 (enExample) |
| BR (1) | BR112016029157A8 (enExample) |
| CA (1) | CA2951766A1 (enExample) |
| MA (1) | MA40232A (enExample) |
| MX (1) | MX2016016318A (enExample) |
| PH (1) | PH12016502482A1 (enExample) |
| RU (1) | RU2698654C2 (enExample) |
| WO (1) | WO2015189832A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11566082B2 (en) | 2014-11-17 | 2023-01-31 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| WO2016149139A1 (en) * | 2015-03-13 | 2016-09-22 | Samsung Bioepis Co., Ltd. | Anti-tnf-alpha polypeptide composition and use thereof |
| JP7031934B2 (ja) | 2016-05-11 | 2022-03-08 | サイティバ・バイオプロセス・アールアンドディ・アクチボラグ | 分離マトリックス |
| JP7106187B2 (ja) | 2016-05-11 | 2022-07-26 | サイティバ・バイオプロセス・アールアンドディ・アクチボラグ | 分離マトリックスを保存する方法 |
| ES2909833T3 (es) | 2016-05-11 | 2022-05-10 | Cytiva Bioprocess R & D Ab | Método de limpieza y/o desinfección de una matriz de separación |
| ES2874974T3 (es) | 2016-05-11 | 2021-11-05 | Cytiva Bioprocess R & D Ab | Matriz de separación |
| US10730908B2 (en) | 2016-05-11 | 2020-08-04 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| US10654887B2 (en) | 2016-05-11 | 2020-05-19 | Ge Healthcare Bio-Process R&D Ab | Separation matrix |
| US10703774B2 (en) | 2016-09-30 | 2020-07-07 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| US10889615B2 (en) | 2016-05-11 | 2021-01-12 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| US12448411B2 (en) | 2016-09-30 | 2025-10-21 | Cytiva Bioprocess R&D Ab | Separation method |
| ES2887046T3 (es) * | 2017-08-17 | 2021-12-21 | Just Evotec Biologics Inc | Método de purificación de proteína glicosilada a partir de galectinas de las células hospedadoras y otros contaminantes |
| EP3676281A1 (en) * | 2017-08-30 | 2020-07-08 | Ares Trading S.A. | Method for purifying proteins |
| US11952399B2 (en) * | 2018-12-18 | 2024-04-09 | Amgen Inc. | Methods for purifying proteins |
| US20220098279A1 (en) * | 2019-01-30 | 2022-03-31 | Amgen Inc. | Aflibercept attributes and methods of characterizing and modifying thereof |
| KR102286892B1 (ko) * | 2019-07-08 | 2021-08-06 | 삼천당제약주식회사 | 안과용 단백질 제제의 정제방법 |
| CN112876567A (zh) * | 2019-11-29 | 2021-06-01 | 广东菲鹏制药股份有限公司 | Fc融合蛋白及其纯化方法 |
| EP4118093A4 (en) * | 2020-03-11 | 2024-04-17 | Dr. Reddy's Laboratories Ltd. | METHOD FOR PURIFYING A FC FUSION PROTEIN |
| CN113563469A (zh) * | 2020-04-28 | 2021-10-29 | 江苏中新医药有限公司 | 高回收率纯化阿达木单抗的方法 |
| WO2022234412A1 (en) * | 2021-05-03 | 2022-11-10 | Lupin Limited | A process for purification of fc-fusion proteins |
| AU2022358612A1 (en) * | 2021-09-28 | 2024-04-11 | Kashiv Biosciences, Llc | An improved process of purification of fusion protein |
| EP4408879A4 (en) * | 2021-09-28 | 2025-08-27 | Kashiv Biosciences Llc | IMPROVED PROCESS FOR PURIFYING FUSION PROTEIN |
| WO2023053030A1 (en) * | 2021-09-28 | 2023-04-06 | Kashiv Biosciences, Llc | An improved process for purification of protein |
| WO2023068740A1 (ko) * | 2021-10-19 | 2023-04-27 | 주식회사 알테오젠 | Igg fc 도메인을 가지는 융합 단백질의 정제방법 |
| US20250026784A1 (en) * | 2021-11-29 | 2025-01-23 | Tosoh Corporation | Separation method of antibody |
| CN119060168A (zh) * | 2024-09-26 | 2024-12-03 | 广东丸美生物技术股份有限公司 | 一种具有低电导率的重组胶原蛋白溶液及其制备方法和应用 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2021284C1 (ru) * | 1991-05-30 | 1994-10-15 | Всесоюзный научно-исследовательский институт технологии кровезаменителей и гормональных препаратов | Способ очистки клинических фракций декстрана |
| US7294481B1 (en) | 1999-01-05 | 2007-11-13 | Immunex Corporation | Method for producing recombinant proteins |
| SI1478394T1 (sl) | 2002-02-27 | 2008-12-31 | Immunex Corp | STABILIZIRAN TNFR-Fc SESTAVEK Z ARGININOM |
| CA2516518A1 (en) | 2003-02-28 | 2004-09-10 | Lonza Biologics Plc. | Antibody purification by protein a and ion exchange chromatography |
| US8263750B2 (en) * | 2006-03-16 | 2012-09-11 | Amgen Inc. | Method for purifying a protein using protein-A affinity chromatography using an intermediate wash step |
| JP2010501622A (ja) * | 2006-08-28 | 2010-01-21 | アレス トレーディング ソシエテ アノニム | Ｆｃ−融合タンパク質の精製法 |
| US8513393B2 (en) * | 2006-08-28 | 2013-08-20 | Ares Trading S.A. | Process for the purification of Fc-containing proteins |
| EP2203465A1 (en) * | 2007-10-22 | 2010-07-07 | Merck Serono S.A. | Method for purifying an fc-containing protein |
| JP2011514895A (ja) * | 2008-02-29 | 2011-05-12 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 精製免疫グロブリン融合タンパク質およびその精製方法 |
| CA2739352C (en) * | 2008-10-29 | 2021-07-13 | Wyeth Llc | Methods for purification of single domain antigen binding molecules |
| KR101753569B1 (ko) * | 2010-01-22 | 2017-07-04 | 베링거 인겔하임 인터내셔날 게엠베하 | Ｆｃ―함유 단백질을 정제하는 크로마토그래피 방법 |
| EP2723759A4 (en) * | 2011-06-24 | 2015-01-28 | Reddys Lab Ltd Dr | PURIFICATION OF CHIMERIC PROTEIN |
| JP6280499B2 (ja) * | 2011-07-08 | 2018-02-14 | メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． | Ｆｃ融合タンパク質の精製方法 |
| KR101454316B1 (ko) * | 2011-08-17 | 2014-10-27 | 한화케미칼 주식회사 | 활성형 ＴＮＦＲ-Ｆｃ 융합 단백질을 제조하는 방법 |
| US9249182B2 (en) | 2012-05-24 | 2016-02-02 | Abbvie, Inc. | Purification of antibodies using hydrophobic interaction chromatography |
| AU2013315750B9 (en) | 2012-09-11 | 2018-11-15 | Coherus Biosciences, Inc. | Correctly folded etanercept in high purity and excellent yield |
| CN102911250B (zh) * | 2012-09-29 | 2014-04-16 | 浙江海正药业股份有限公司 | 酸性重组蛋白药物的纯化方法 |
| US9649383B2 (en) * | 2012-11-19 | 2017-05-16 | Merck Sharp & Dohme Corp. | Liquid formulations for TNFR:Fc fusion proteins |
| AU2014240596B2 (en) * | 2013-03-14 | 2018-09-27 | Amgen Inc. | Removal of leaked affinity purification ligand |
| US8946395B1 (en) * | 2013-10-18 | 2015-02-03 | Abbvie Inc. | Purification of proteins using hydrophobic interaction chromatography |
-
2015
- 2015-06-13 WO PCT/IB2015/054494 patent/WO2015189832A1/en not_active Ceased
- 2015-06-13 AU AU2015273049A patent/AU2015273049B2/en not_active Ceased
- 2015-06-13 CA CA2951766A patent/CA2951766A1/en not_active Abandoned
- 2015-06-13 CN CN201580038801.XA patent/CN106536565A/zh active Pending
- 2015-06-13 MX MX2016016318A patent/MX2016016318A/es unknown
- 2015-06-13 US US15/318,489 patent/US10556942B2/en active Active
- 2015-06-13 JP JP2016572703A patent/JP6747985B2/ja not_active Expired - Fee Related
- 2015-06-13 MA MA040232A patent/MA40232A/fr unknown
- 2015-06-13 RU RU2017100005A patent/RU2698654C2/ru active
- 2015-06-13 EP EP15734731.1A patent/EP3155009A1/en not_active Withdrawn
- 2015-06-13 BR BR112016029157A patent/BR112016029157A8/pt not_active Application Discontinuation
-
2016
- 2016-12-13 PH PH12016502482A patent/PH12016502482A1/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2017100005A (ru) | Способ очистки белка слияния | |
| JP2018510867A5 (enExample) | ||
| Spriestersbach et al. | Purification of his-tagged proteins | |
| Peterson et al. | [1] Column chromatography of proteins: Substituted celluloses | |
| Zhu et al. | Hydrophilic-interaction chromatography of peptides on hydrophilic and strong cation-exchange columns | |
| JP6092892B2 (ja) | 抗体の精製方法 | |
| Furie et al. | Interaction of lanthanide ions with bovine factor X and their use in the affinity chromatography of the venom coagulant protein of Vipera russelli | |
| US10053489B2 (en) | Method for purifying antibody | |
| JP2014520814A5 (enExample) | ||
| BRPI0611600B8 (pt) | método para purificação de uma proteína tendo uma região fc a partir de um líquido fonte compreendendo a proteína e uma ou mais impurezas, e kit | |
| Holstein et al. | Improving selectivity in multimodal chromatography using controlled pH gradient elution | |
| JP2017517745A5 (enExample) | ||
| US20200017545A1 (en) | Methods and Reagents for Purification of Proteins | |
| AU2012322949B2 (en) | Protein purification by anion exchange chromatography | |
| JP5883849B2 (ja) | 陰イオン交換樹脂を用いる二価カチオン結合タンパク質の精製方法 | |
| CN104109202A (zh) | 一种从血浆中吸附人凝血酶原复合物的方法 | |
| JP2016538264A (ja) | 組換えタンパク質の精製方法 | |
| EP4389143A3 (en) | Selective reduction of cysteine residues in il-17 antibodies | |
| US12358946B2 (en) | Method for purifying antibodies | |
| JP2017514803A (ja) | ゴナドトロピンの新規の精製方法 | |
| Xin et al. | Development of universal purification protocols for fibrinolytic enzyme-producing bacilli | |
| Ritzén et al. | Endotoxin reduction in monoclonal antibody preparations using arginine | |
| Rajak et al. | Purification of monoclonal antibodies, IgG1, from cell culture supernatant by use of metal chelate convective interaction media monolithic columns | |
| CN106496302B (zh) | 一种用离子交换层析纯化蛋白质的方法 | |
| Ng et al. | pH‐based cation exchange chromatography in the capture and elution of monoclonal antibodies |