JP2017520763A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017520763A5 JP2017520763A5 JP2016571689A JP2016571689A JP2017520763A5 JP 2017520763 A5 JP2017520763 A5 JP 2017520763A5 JP 2016571689 A JP2016571689 A JP 2016571689A JP 2016571689 A JP2016571689 A JP 2016571689A JP 2017520763 A5 JP2017520763 A5 JP 2017520763A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- tumor
- autoantibodies
- bead
- patient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000011324 bead Substances 0.000 claims 18
- 102000004169 proteins and genes Human genes 0.000 claims 12
- 108090000623 proteins and genes Proteins 0.000 claims 12
- 238000000034 method Methods 0.000 claims 11
- 239000000107 tumor biomarker Substances 0.000 claims 7
- 239000004005 microsphere Substances 0.000 claims 6
- 206010028980 Neoplasm Diseases 0.000 claims 5
- 210000002966 serum Anatomy 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 4
- 239000002299 complementary DNA Substances 0.000 claims 4
- 239000000090 biomarker Substances 0.000 claims 3
- 201000007270 liver cancer Diseases 0.000 claims 3
- 208000014018 liver neoplasm Diseases 0.000 claims 3
- 210000004881 tumor cell Anatomy 0.000 claims 3
- 102100039435 C-X-C motif chemokine 17 Human genes 0.000 claims 2
- 101100356682 Caenorhabditis elegans rho-1 gene Proteins 0.000 claims 2
- 102400000686 Endothelin-1 Human genes 0.000 claims 2
- 101800004490 Endothelin-1 Proteins 0.000 claims 2
- 102000003973 Fibroblast growth factor 21 Human genes 0.000 claims 2
- 108090000376 Fibroblast growth factor 21 Proteins 0.000 claims 2
- 102100031001 Hepatoma-derived growth factor-related protein 2 Human genes 0.000 claims 2
- 101000889048 Homo sapiens C-X-C motif chemokine 17 Proteins 0.000 claims 2
- 101100450337 Homo sapiens HDGFL2 gene Proteins 0.000 claims 2
- 101100177327 Homo sapiens HDGFL3 gene Proteins 0.000 claims 2
- 101000853000 Homo sapiens Interleukin-26 Proteins 0.000 claims 2
- 101000945751 Homo sapiens Leukocyte cell-derived chemotaxin-2 Proteins 0.000 claims 2
- 101000697529 Homo sapiens Stathmin-4 Proteins 0.000 claims 2
- 101000852559 Homo sapiens Thioredoxin Proteins 0.000 claims 2
- 101000807354 Homo sapiens Ubiquitin-conjugating enzyme E2 C Proteins 0.000 claims 2
- 108050003558 Interleukin-17 Proteins 0.000 claims 2
- 102000013691 Interleukin-17 Human genes 0.000 claims 2
- 102100036679 Interleukin-26 Human genes 0.000 claims 2
- 102100034762 Leukocyte cell-derived chemotaxin-2 Human genes 0.000 claims 2
- 108010092801 Midkine Proteins 0.000 claims 2
- 102000016776 Midkine Human genes 0.000 claims 2
- 101100058550 Mus musculus Bmi1 gene Proteins 0.000 claims 2
- 101150111584 RHOA gene Proteins 0.000 claims 2
- 101710081624 Small ubiquitin-related modifier 4 Proteins 0.000 claims 2
- 102100024535 Small ubiquitin-related modifier 4 Human genes 0.000 claims 2
- 102100028049 Stathmin-4 Human genes 0.000 claims 2
- 108010021188 Superoxide Dismutase-1 Proteins 0.000 claims 2
- 102000008221 Superoxide Dismutase-1 Human genes 0.000 claims 2
- 102100036407 Thioredoxin Human genes 0.000 claims 2
- 102100037256 Ubiquitin-conjugating enzyme E2 C Human genes 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 206010073071 hepatocellular carcinoma Diseases 0.000 claims 2
- 231100000844 hepatocellular carcinoma Toxicity 0.000 claims 2
- 238000001574 biopsy Methods 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 238000004949 mass spectrometry Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- CWEFIMQKSZFZNY-UHFFFAOYSA-N pentyl 2-[4-[[4-[4-[[4-[[4-(pentoxycarbonylamino)phenyl]methyl]phenyl]carbamoyloxy]butoxycarbonylamino]phenyl]methyl]phenyl]acetate Chemical compound C1=CC(CC(=O)OCCCCC)=CC=C1CC(C=C1)=CC=C1NC(=O)OCCCCOC(=O)NC(C=C1)=CC=C1CC1=CC=C(NC(=O)OCCCCC)C=C1 CWEFIMQKSZFZNY-UHFFFAOYSA-N 0.000 claims 1
- 239000013612 plasmid Substances 0.000 claims 1
- 238000011002 quantification Methods 0.000 claims 1
- 239000000439 tumor marker Substances 0.000 claims 1
- 238000005406 washing Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/321,870 | 2014-07-02 | ||
| US14/321,867 US9506925B2 (en) | 2014-07-02 | 2014-07-02 | Specific biomarker set for non-invasive diagnosis of liver cancer |
| US14/321,870 US9885718B2 (en) | 2014-07-02 | 2014-07-02 | Specific biomarker set for non-invasive diagnosis of liver cancer |
| US14/321,867 | 2014-07-02 | ||
| PCT/US2014/049038 WO2016003479A1 (en) | 2014-07-02 | 2014-07-31 | Specific biomarker set for non-invasive diagnosis of liver cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020106731A Division JP2020160082A (ja) | 2014-07-02 | 2020-06-22 | 肝臓癌の非侵襲性診断のための特異的バイオマーカーセット |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017520763A JP2017520763A (ja) | 2017-07-27 |
| JP2017520763A5 true JP2017520763A5 (enExample) | 2017-09-21 |
Family
ID=55019816
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016571689A Pending JP2017520763A (ja) | 2014-07-02 | 2014-07-31 | 肝臓癌の非侵襲性診断のための特異的バイオマーカーセット |
| JP2020106731A Withdrawn JP2020160082A (ja) | 2014-07-02 | 2020-06-22 | 肝臓癌の非侵襲性診断のための特異的バイオマーカーセット |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020106731A Withdrawn JP2020160082A (ja) | 2014-07-02 | 2020-06-22 | 肝臓癌の非侵襲性診断のための特異的バイオマーカーセット |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP3164711A4 (enExample) |
| JP (2) | JP2017520763A (enExample) |
| KR (1) | KR102086788B1 (enExample) |
| CN (2) | CN105319362B (enExample) |
| AU (2) | AU2014399919B2 (enExample) |
| CA (1) | CA2939912C (enExample) |
| MY (2) | MY195045A (enExample) |
| NZ (1) | NZ722492A (enExample) |
| SG (1) | SG11201606106SA (enExample) |
| TW (1) | TWI700493B (enExample) |
| UY (1) | UY36200A (enExample) |
| WO (1) | WO2016003479A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106383231B (zh) * | 2016-09-02 | 2020-03-17 | 四川大学 | 一种诊断肝癌的标记物组合及其应用 |
| GB201619954D0 (en) * | 2016-11-25 | 2017-01-11 | Oncimmune Ltd | Antibody assay |
| KR102175265B1 (ko) | 2019-03-13 | 2020-11-06 | 충남대학교산학협력단 | Txndc7을 포함하는 간세포암종 진단 또는 예후 예측용 바이오마커 조성물 |
| CN110646615B (zh) * | 2019-08-27 | 2021-07-13 | 南方医科大学 | 肝纤维化的生物学标志物、治疗靶点及其用途 |
| WO2023282916A1 (en) | 2021-07-09 | 2023-01-12 | Guardant Health, Inc. | Methods of detecting genomic rearrangements using cell free nucleic acids |
| ES2987661T3 (es) | 2020-07-10 | 2024-11-15 | Guardant Health Inc | Métodos de detección de reordenamientos genómicos utilizando ácidos nucleicos libres de células |
| CN113502328A (zh) * | 2021-05-27 | 2021-10-15 | 深圳市人民医院 | 检测样本中标志物表达水平的试剂在制备用于检测或诊断乳腺癌的试剂盒中的应用 |
| CN113777295B (zh) * | 2021-09-15 | 2024-03-19 | 江南大学 | 用于检测肿瘤标志物pd-l1的高灵敏度量子点探针、制备方法及应用 |
| CN113956344A (zh) * | 2021-10-14 | 2022-01-21 | 江南大学 | 一种新型治疗肝癌的fgf类似物及其应用 |
| CN114113611B (zh) * | 2021-12-13 | 2023-07-14 | 郑州大学 | 一种用于肝癌诊断的生物标志物及检测试剂盒 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6449562B1 (en) * | 1996-10-10 | 2002-09-10 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and method |
| US6893844B1 (en) * | 1998-09-22 | 2005-05-17 | Long Yu | DNA encoding a new human hepatoma derived growth factor and producing method thereof |
| US7387881B2 (en) * | 2001-09-19 | 2008-06-17 | The Regents Of The University Of Michigan | Detection and treatment of cancers of the liver |
| AU2002361908A1 (en) * | 2001-12-31 | 2003-07-24 | Quark Biotech, Inc. | Methods for identifying marker genes for cancer |
| GB0228900D0 (en) * | 2002-12-11 | 2003-01-15 | Ml Lab Plc | Cancer Immunotherapy |
| JP3960614B2 (ja) * | 2003-08-31 | 2007-08-15 | 株式会社イムノディア | 抗ペプチド抗体測定法とペプチドワクチンのワクチン候補選択方法 |
| GB0406215D0 (en) * | 2004-03-19 | 2004-04-21 | Procure Therapeutics Ltd | Prostate stem cell |
| WO2005123944A1 (en) * | 2004-06-18 | 2005-12-29 | Roche Diagnostics Gmbh | Use of protein pdx1 as a marker for breast cancer |
| JP5211315B2 (ja) | 2006-07-25 | 2013-06-12 | 国立大学法人愛媛大学 | 腫瘍マーカ、腫瘍診断キットおよび腫瘍マーカの測定方法 |
| KR20100040964A (ko) * | 2007-08-10 | 2010-04-21 | 가꼬우호우징 효고 이카다이가쿠 | 신규 간암 마커 |
| US8512963B2 (en) * | 2009-11-25 | 2013-08-20 | The Johns Hopkins University | Detection and quantitation of full-length thioredoxin (TRX) and truncated thioredoxin (TRX 80) in complex samples |
| US9523680B2 (en) * | 2010-06-30 | 2016-12-20 | Ambergen, Inc. | Global Proteomic screening of random bead arrays using mass spectrometry imaging |
| JP5493130B2 (ja) | 2010-08-25 | 2014-05-14 | 国立大学法人山口大学 | 自己抗体の検出方法 |
| EP2678448A4 (en) * | 2011-02-22 | 2014-10-01 | Caris Life Sciences Luxembourg Holdings S A R L | CIRCULATING BIOMARKERS |
| US20130130355A1 (en) * | 2011-09-28 | 2013-05-23 | Armune Biosciences, Inc. | Method and system of particle-phage epitope complex |
-
2014
- 2014-07-31 CA CA2939912A patent/CA2939912C/en active Active
- 2014-07-31 EP EP14896556.9A patent/EP3164711A4/en not_active Withdrawn
- 2014-07-31 WO PCT/US2014/049038 patent/WO2016003479A1/en not_active Ceased
- 2014-07-31 KR KR1020167032783A patent/KR102086788B1/ko not_active Expired - Fee Related
- 2014-07-31 TW TW103126171A patent/TWI700493B/zh not_active IP Right Cessation
- 2014-07-31 SG SG11201606106SA patent/SG11201606106SA/en unknown
- 2014-07-31 JP JP2016571689A patent/JP2017520763A/ja active Pending
- 2014-07-31 AU AU2014399919A patent/AU2014399919B2/en not_active Ceased
- 2014-07-31 MY MYPI2016002278A patent/MY195045A/en unknown
- 2014-07-31 NZ NZ72249214A patent/NZ722492A/en not_active IP Right Cessation
- 2014-07-31 MY MYPI2017001446A patent/MY179845A/en unknown
-
2015
- 2015-07-01 UY UY0001036200A patent/UY36200A/es unknown
- 2015-07-01 CN CN201510379493.9A patent/CN105319362B/zh not_active Expired - Fee Related
- 2015-07-01 CN CN201710545890.8A patent/CN107478842B/zh not_active Expired - Fee Related
-
2017
- 2017-09-21 AU AU2017232129A patent/AU2017232129B2/en not_active Ceased
-
2020
- 2020-06-22 JP JP2020106731A patent/JP2020160082A/ja not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017520763A5 (enExample) | ||
| JP6672411B2 (ja) | 癌療法を示すためのｓｒｍアッセイ | |
| ES2641294T3 (es) | Nuevo anticuerpo para el diagnóstico y/o el pronóstico del cáncer | |
| JP2012019790A5 (enExample) | ||
| Jeong et al. | Plasmon‐enhanced single extracellular vesicle analysis for cholangiocarcinoma diagnosis | |
| JP2015533788A5 (enExample) | ||
| US20170176423A1 (en) | Magnetic programmable bead enzyme-linked immunosorbent assay | |
| JP2016507723A5 (enExample) | ||
| RU2016116773A (ru) | Способ выявления опухоли поджелудочной железы, антитела и набор для выявления опухоли поджелудочной железы | |
| JP2009539082A5 (enExample) | ||
| WO2006110589A3 (en) | Gammaretrovirus associated with cancer | |
| WO2014167969A1 (ja) | 大腸がんの検出方法 | |
| He et al. | Analytical platform evaluation for quantification of ERG in prostate cancer using protein and mRNA detection methods | |
| JP2019058171A (ja) | Ｐｄ−ｌ１に対するｓｒｍアッセイ | |
| WO2015182580A1 (ja) | 大腸がんの転移検出方法 | |
| JP6441215B2 (ja) | 肺組織像を細分類するためのｓｒｍ／ｍｒｍ分析 | |
| JP2018515071A5 (enExample) | ||
| JP2012531612A5 (enExample) | ||
| Song et al. | The value of circulating CYFRA21-1 expression in patients with nasopharyngeal carcinoma: a study of 529 subjects | |
| Xu et al. | Rta-IgG as a biomarker for diagnosis and post treatment prognostic of nasopharyngeal carcinoma | |
| JP2018520366A5 (enExample) | ||
| CN108738347B (zh) | 辅助肝细胞癌患者的再发风险预测的方法、装置、计算机程序制品及试剂盒 | |
| CN106383231B (zh) | 一种诊断肝癌的标记物组合及其应用 | |
| RU2745060C2 (ru) | Биомаркеры для комбинированной терапии, включающей ленватиниб и эверолимус | |
| Wang et al. | Distinguishing of tumor cell-targeting peptide ligands through a color-encoding microarray |