JP2017519780A5 - - Google Patents
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- Publication number
- JP2017519780A5 JP2017519780A5 JP2016575325A JP2016575325A JP2017519780A5 JP 2017519780 A5 JP2017519780 A5 JP 2017519780A5 JP 2016575325 A JP2016575325 A JP 2016575325A JP 2016575325 A JP2016575325 A JP 2016575325A JP 2017519780 A5 JP2017519780 A5 JP 2017519780A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- unsubstituted
- hydrogen
- interferon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- HWPZZUQOWRWFDB-UHFFFAOYSA-N CN(C=CC(N)=N1)C1=O Chemical compound CN(C=CC(N)=N1)C1=O HWPZZUQOWRWFDB-UHFFFAOYSA-N 0.000 description 2
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462016219P | 2014-06-24 | 2014-06-24 | |
| US62/016,219 | 2014-06-24 | ||
| US201462034629P | 2014-08-07 | 2014-08-07 | |
| US62/034,629 | 2014-08-07 | ||
| US201462061819P | 2014-10-09 | 2014-10-09 | |
| US62/061,819 | 2014-10-09 | ||
| PCT/US2015/036958 WO2015200205A1 (en) | 2014-06-24 | 2015-06-22 | Substituted nucleosides, nucleotides and analogs thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017519780A JP2017519780A (ja) | 2017-07-20 |
| JP2017519780A5 true JP2017519780A5 (enExample) | 2018-09-13 |
| JP6669675B2 JP6669675B2 (ja) | 2020-03-18 |
Family
ID=54868667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016575325A Expired - Fee Related JP6669675B2 (ja) | 2014-06-24 | 2015-06-22 | 置換ヌクレオシド、ヌクレオチドおよびその類似体 |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US9603863B2 (enExample) |
| EP (1) | EP3160475B1 (enExample) |
| JP (1) | JP6669675B2 (enExample) |
| CN (1) | CN106604734B (enExample) |
| AP (1) | AP2016009653A0 (enExample) |
| AU (1) | AU2015280234B2 (enExample) |
| CA (1) | CA2952959C (enExample) |
| EA (1) | EA201692537A1 (enExample) |
| IL (1) | IL249627A0 (enExample) |
| MA (1) | MA40031A (enExample) |
| MX (1) | MX2016017381A (enExample) |
| NZ (1) | NZ727582A (enExample) |
| PH (1) | PH12016502563A1 (enExample) |
| SG (1) | SG11201610597QA (enExample) |
| TN (1) | TN2016000566A1 (enExample) |
| TW (1) | TW201613613A (enExample) |
| WO (1) | WO2015200205A1 (enExample) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2524356T3 (es) | 2010-07-22 | 2014-12-05 | Gilead Sciences, Inc. | Métodos y compuestos para tratar infecciones provocadas por virus Paramyxoviridae |
| SG10201610936RA (en) | 2011-12-22 | 2017-02-27 | Alios Biopharma Inc | Substituted nucleosides, nucleotides and analogs thereof |
| US8980865B2 (en) | 2011-12-22 | 2015-03-17 | Alios Biopharma, Inc. | Substituted nucleotide analogs |
| US8916538B2 (en) | 2012-03-21 | 2014-12-23 | Vertex Pharmaceuticals Incorporated | Solid forms of a thiophosphoramidate nucleotide prodrug |
| US9441007B2 (en) | 2012-03-21 | 2016-09-13 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| USRE48171E1 (en) | 2012-03-21 | 2020-08-25 | Janssen Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| GEP201706757B (en) | 2012-12-21 | 2017-10-25 | Alios Biopharma Inc | Substituted nucleosides, nucleotides and analogs thereof |
| US9598457B2 (en) | 2012-12-21 | 2017-03-21 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| AU2014248116A1 (en) | 2013-04-05 | 2015-11-12 | Alios Biopharma, Inc. | Hepatitis C viral infection treatment using a combination of compounds |
| HK1224229A1 (zh) | 2013-06-26 | 2017-08-18 | Alios Biopharma, Inc. | 取代的核苷，核苷酸及其类似物 |
| EP3424938B1 (en) | 2013-06-26 | 2020-07-22 | Janssen BioPharma, Inc. | 4'-azidoalkyl-substituted nucleosides, nucleotides and analogs thereof |
| JP6562908B2 (ja) | 2013-10-11 | 2019-08-21 | ヤンセン バイオファーマ インク． | 置換ヌクレオシド、置換ヌクレオチドおよびその類似体 |
| TN2016000566A1 (en) | 2014-06-24 | 2018-04-04 | Alios Biopharma Inc | Substituted nucleosides, nucleotides and analogs thereof |
| HUE051986T2 (hu) | 2014-06-24 | 2021-04-28 | Janssen Biopharma Inc | Helyettesített nukleozidok, nukleotidek és analógjaik virális fertõzés kezelésére való alkalmazásra |
| BR112017006264A2 (pt) | 2014-09-26 | 2017-12-12 | Riboscience Llc | derivados de nucleosídeo substituído com 4?-vinila como inibidores de replicação de rna do vírus sincitial respiratório |
| US20170246209A1 (en) * | 2014-10-06 | 2017-08-31 | Nantkwest, Inc. | Treating viral hemorrhagic fever with nk-92 cells |
| HK1243714A1 (zh) | 2014-10-28 | 2018-07-20 | Alios Biopharma, Inc. | 制备取代的核苷类似物的方法 |
| MA41213A (fr) | 2014-12-19 | 2017-10-24 | Alios Biopharma Inc | Nucléosides substitués, nucléotides et analogues de ceux-ci |
| MA41441A (fr) | 2014-12-19 | 2017-12-12 | Alios Biopharma Inc | Nucléosides substitués, nucléotides et analogues de ceux-ci |
| IL296496B2 (en) | 2014-12-26 | 2024-10-01 | Univ Emory | N4-hydroxycytidine and derivatives and anti-viral uses related thereto |
| GEP20217282B (en) | 2015-03-06 | 2021-08-10 | Atea Pharmaceuticals Inc | β-D-2'-DEOXY-2'α-FLUORO-2'-β-C-SUBSTITUTED-2-MODIFIED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR HCV TREATMENT |
| EA036776B1 (ru) | 2015-03-11 | 2020-12-21 | Янссен Байофарма, Инк. | Соединения азапиридона и способы их применения |
| JP7129703B2 (ja) * | 2016-04-28 | 2022-09-02 | エモリー ユニバーシティー | アルキン含有ヌクレオチド及びヌクレオシド治療組成物並びにそれらに関連した使用 |
| US10202412B2 (en) | 2016-07-08 | 2019-02-12 | Atea Pharmaceuticals, Inc. | β-D-2′-deoxy-2′-substituted-4′-substituted-2-substituted-N6-substituted-6-aminopurinenucleotides for the treatment of paramyxovirus and orthomyxovirus infections |
| PT3512863T (pt) | 2016-09-07 | 2022-03-09 | Atea Pharmaceuticals Inc | Nucleótidos de purina 2'-substituídos-n6-substituídos para tratamento de vírus de rna |
| CN110248951B (zh) | 2017-02-01 | 2022-10-28 | 阿堤亚制药公司 | 用于治疗丙型肝炎病毒的核苷酸半硫酸盐 |
| WO2018204198A1 (en) | 2017-05-01 | 2018-11-08 | Gilead Sciences, Inc. | Crystalline forms of (s) 2 ethylbutyl 2 (((s) (((2r,3s,4r,5r) 5 (4 aminopyrrolo[2,1-f] [1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2 yl)methoxy)(phenoxy) phosphoryl)amino)propanoate |
| EP4512475A3 (en) | 2017-07-11 | 2025-05-14 | Gilead Sciences, Inc. | Compositions comprising an rna polymerase inhibitor and cyclodextrin for treating viral infections |
| CA3075950A1 (en) * | 2017-09-18 | 2019-03-21 | Janssen Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| KR102626210B1 (ko) | 2017-12-07 | 2024-01-18 | 에모리 유니버시티 | N4-하이드록시사이티딘 및 유도체 및 이와 관련된 항-바이러스 용도 |
| IL277160B2 (en) * | 2018-03-07 | 2024-10-01 | Univ Emory | 4'-halogen containing nucleotide and nucleoside therapeutic compositions and uses related thereto |
| WO2019200005A1 (en) | 2018-04-10 | 2019-10-17 | Atea Pharmaceuticals, Inc. | Treatment of hcv infected patients with cirrhosis |
| EP3934760A1 (en) | 2019-03-06 | 2022-01-12 | GlaxoSmithKline Intellectual Property (No.2) Limited | Compounds useful in hiv therapy |
| CA3134613A1 (en) * | 2019-04-02 | 2020-10-08 | Aligos Therapeutics, Inc. | Compounds targeting prmt5 |
| AU2021214911A1 (en) | 2020-01-27 | 2022-07-21 | Gilead Sciences, Inc. | Methods for treating SARS CoV-2 infections |
| TWI794742B (zh) | 2020-02-18 | 2023-03-01 | 美商基利科學股份有限公司 | 抗病毒化合物 |
| TWI874791B (zh) | 2020-02-18 | 2025-03-01 | 美商基利科學股份有限公司 | 抗病毒化合物 |
| AU2021224588B2 (en) * | 2020-02-18 | 2024-07-18 | Gilead Sciences, Inc. | Antiviral compounds |
| US10874687B1 (en) | 2020-02-27 | 2020-12-29 | Atea Pharmaceuticals, Inc. | Highly active compounds against COVID-19 |
| CN118994170A (zh) | 2020-03-12 | 2024-11-22 | 吉利德科学公司 | 制备1'-氰基核苷的方法 |
| CA3169348A1 (en) | 2020-03-20 | 2021-09-23 | Gilead Sciences, Inc. | Prodrugs of 4'-c-substituted-2-halo-2'-deoxyadenosine nucleosides and methods of making and using the same |
| EP4132651B1 (en) | 2020-04-06 | 2026-03-18 | Gilead Sciences, Inc. | Inhalation formulations of 1'-cyano substituted carbanucleoside analogs |
| AU2021255809A1 (en) * | 2020-04-14 | 2022-12-15 | Janssen Pharmaceuticals, Inc. | Bi- and monocyclic nucleoside analogs for treatment of hepatitis E |
| ES3041698T3 (en) | 2020-05-29 | 2025-11-13 | Gilead Sciences Inc | Remdesivir for the treatment of viral infections |
| CA3187821A1 (en) | 2020-06-24 | 2021-12-30 | Gilead Sciences, Inc. | 1'-cyano nucleoside analogs and uses thereof |
| MX2023002233A (es) | 2020-08-24 | 2023-03-15 | Gilead Sciences Inc | Compuestos fosfolipidos y usos de estos. |
| WO2022047065A2 (en) | 2020-08-27 | 2022-03-03 | Gilead Sciences, Inc. | Compounds and methods for treatment of viral infections |
| TWI811812B (zh) | 2020-10-16 | 2023-08-11 | 美商基利科學股份有限公司 | 磷脂化合物及其用途 |
| JP7688152B2 (ja) | 2021-04-16 | 2025-06-03 | ギリアード サイエンシーズ， インコーポレイテッド | アミドを使用してカルバヌクレオシドを調製する方法 |
| BR112023026356A2 (pt) | 2021-06-17 | 2024-03-05 | Atea Pharmaceuticals Inc | Método para tratar vírus da hepatite c ou uma condição resultante de uma infecção por hepatite c, combinação, uso da combinação, composição farmacêutica, e, kit para o tratamento de vírus da hepatite c |
| CN113735929A (zh) * | 2021-07-21 | 2021-12-03 | 海化生命(厦门)科技有限公司 | 一种抗冠状病毒的化合物及其制备方法与应用 |
| JP7719954B2 (ja) | 2021-08-18 | 2025-08-06 | ギリアード サイエンシーズ， インコーポレイテッド | リン脂質化合物並びにその製造方法及び使用方法 |
| US11541071B1 (en) | 2021-12-16 | 2023-01-03 | Ascletis BioScience Co., Ltd | Nucleoside derivatives and methods of use thereof |
| CN116554249B (zh) * | 2022-01-28 | 2025-03-18 | 北京恩泰伟医药科技有限公司 | 抗病毒化合物及其用途 |
| TW202525810A (zh) | 2022-03-02 | 2025-07-01 | 美商基利科學股份有限公司 | 用於治療病毒感染的化合物及方法 |
| EP4493573A1 (en) | 2022-03-15 | 2025-01-22 | Rome Therapeutics, Inc. | Compounds and methods for treating disease |
| US20250282812A1 (en) * | 2022-04-20 | 2025-09-11 | Shanghai Institute Of Materia Medica , Chinese Academy Of Sciences | Antiviral nucleoside analogue, and pharmaceutical composition and use thereof |
| CN116535385B (zh) * | 2022-08-29 | 2025-03-11 | 苏州华一新能源科技股份有限公司 | 一种制备硫酸乙烯酯的方法 |
| US12357577B1 (en) | 2024-02-02 | 2025-07-15 | Gilead Sciences, Inc. | Pharmaceutical formulations and uses thereof |
| CN116589510B (zh) * | 2023-04-20 | 2025-08-26 | 安徽大学 | 一种氟代苄基核糖中间体的制备方法与应用 |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5432272A (en) | 1990-10-09 | 1995-07-11 | Benner; Steven A. | Method for incorporating into a DNA or RNA oligonucleotide using nucleotides bearing heterocyclic bases |
| SI1355916T1 (sl) | 2001-01-22 | 2007-04-30 | Merck & Co Inc | Nukleozidni derivati kot inhibitorji RNA-odvisne RNA virusne polimeraze |
| WO2002069903A2 (en) * | 2001-03-06 | 2002-09-12 | Biocryst Pharmaceuticals, Inc. | Nucleosides, preparation thereof and use as inhibitors of rna viral polymerases |
| US20040138170A1 (en) | 2002-03-06 | 2004-07-15 | Montgomery John A. | Nucleosides, preparation thereof and use as inhibitors of rna viral polymerases |
| ATE465742T1 (de) * | 2003-09-05 | 2010-05-15 | Anadys Pharmaceuticals Inc | Tlr7-liganden zur behandlung von hepatitis c |
| JP2008508319A (ja) * | 2004-07-29 | 2008-03-21 | メタバシス・セラピューティクス・インコーポレイテッド | 新規ヌクレオシド誘導体 |
| US20090318380A1 (en) | 2007-11-20 | 2009-12-24 | Pharmasset, Inc. | 2',4'-substituted nucleosides as antiviral agents |
| US20090176732A1 (en) | 2007-12-21 | 2009-07-09 | Alios Biopharma Inc. | Protected nucleotide analogs |
| US8475804B2 (en) | 2009-02-20 | 2013-07-02 | U.S. Army Medical Research And Material Command | Compositions and methods for treatment of filovirus-mediated diseases |
| US20100240604A1 (en) * | 2009-03-20 | 2010-09-23 | Alios Biopharma, Inc. | Protected nucleotide analogs |
| AU2010226466A1 (en) * | 2009-03-20 | 2011-10-20 | Alios Biopharma, Inc. | Substituted nucleoside and nucleotide analogs |
| WO2012040126A1 (en) | 2010-09-22 | 2012-03-29 | Alios Biopharma, Inc. | Substituted nucleotide analogs |
| GEP20156313B (en) | 2010-09-22 | 2015-07-10 | Alios Biopharma Inc | Substituted nucleotide analogs |
| EP2619215B1 (en) | 2010-09-22 | 2018-09-05 | Alios Biopharma, Inc. | Azido nucleosides and nucleotide analogs |
| EP2655392B1 (en) | 2010-12-22 | 2018-04-18 | Alios Biopharma, Inc. | Cyclic nucleotide analogs |
| UA111761C2 (uk) | 2011-12-20 | 2016-06-10 | Рібосаєнс Ллс | 2',4'-дифтор-2'-метилзаміщені нуклеозидні похідні як інгібітори реплікації phk вірусу гепатиту c |
| SG10201610936RA (en) | 2011-12-22 | 2017-02-27 | Alios Biopharma Inc | Substituted nucleosides, nucleotides and analogs thereof |
| US8980865B2 (en) | 2011-12-22 | 2015-03-17 | Alios Biopharma, Inc. | Substituted nucleotide analogs |
| US9441007B2 (en) | 2012-03-21 | 2016-09-13 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| RS58437B1 (sr) * | 2012-03-21 | 2019-04-30 | Alios Biopharma Inc | Supstituisani nukleozidi, nukleotidi i njihovi analozi |
| HK1203513A1 (en) | 2012-03-21 | 2015-10-30 | 艾丽奥斯生物制药有限公司 | Methods of preparing substituted nucleotide analogs |
| US8916538B2 (en) | 2012-03-21 | 2014-12-23 | Vertex Pharmaceuticals Incorporated | Solid forms of a thiophosphoramidate nucleotide prodrug |
| WO2013142159A1 (en) | 2012-03-21 | 2013-09-26 | Alios Biopharma, Inc. | Pharmaceutical combinations comprising a thionucleotide analog |
| EP2827876A4 (en) | 2012-03-22 | 2015-10-28 | Alios Biopharma Inc | PHARMACEUTICAL COMBINATIONS WITH A THIONUCLEOTIDE ANALOG |
| EP2935304A1 (en) | 2012-12-19 | 2015-10-28 | IDENIX Pharmaceuticals, Inc. | 4'-fluoro nucleosides for the treatment of hcv |
| US9598457B2 (en) | 2012-12-21 | 2017-03-21 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| GEP201706757B (en) | 2012-12-21 | 2017-10-25 | Alios Biopharma Inc | Substituted nucleosides, nucleotides and analogs thereof |
| TW201526899A (zh) | 2013-02-28 | 2015-07-16 | Alios Biopharma Inc | 醫藥組成物 |
| WO2014164533A1 (en) | 2013-03-11 | 2014-10-09 | Vertex Pharmaceuticals Incorporated | Methods of stereoselective synthesis of substituted nucleoside analogs |
| AU2014248116A1 (en) | 2013-04-05 | 2015-11-12 | Alios Biopharma, Inc. | Hepatitis C viral infection treatment using a combination of compounds |
| HK1224229A1 (zh) | 2013-06-26 | 2017-08-18 | Alios Biopharma, Inc. | 取代的核苷，核苷酸及其类似物 |
| EP3424938B1 (en) | 2013-06-26 | 2020-07-22 | Janssen BioPharma, Inc. | 4'-azidoalkyl-substituted nucleosides, nucleotides and analogs thereof |
| DK3043803T3 (da) | 2013-09-11 | 2022-08-01 | Univ Emory | Nukleotid- og nucleosidsammensætninger og deres anvendelse |
| JP6562908B2 (ja) | 2013-10-11 | 2019-08-21 | ヤンセン バイオファーマ インク． | 置換ヌクレオシド、置換ヌクレオチドおよびその類似体 |
| TN2016000566A1 (en) | 2014-06-24 | 2018-04-04 | Alios Biopharma Inc | Substituted nucleosides, nucleotides and analogs thereof |
| HUE051986T2 (hu) | 2014-06-24 | 2021-04-28 | Janssen Biopharma Inc | Helyettesített nukleozidok, nukleotidek és analógjaik virális fertõzés kezelésére való alkalmazásra |
| BR112016029994A2 (pt) | 2014-06-24 | 2017-08-22 | Alios Biopharma Inc | métodos de preparação de análogos de nucleotídeo substituídos |
| JP2017525681A (ja) | 2014-07-22 | 2017-09-07 | アリオス バイオファーマ インク． | パラミクソウイルスの治療方法 |
| JP2017523988A (ja) | 2014-08-05 | 2017-08-24 | アリオス バイオファーマ インク． | パラミクソウイルスを治療するための併用療法 |
| HK1243714A1 (zh) | 2014-10-28 | 2018-07-20 | Alios Biopharma, Inc. | 制备取代的核苷类似物的方法 |
| MA41441A (fr) | 2014-12-19 | 2017-12-12 | Alios Biopharma Inc | Nucléosides substitués, nucléotides et analogues de ceux-ci |
| MA41213A (fr) | 2014-12-19 | 2017-10-24 | Alios Biopharma Inc | Nucléosides substitués, nucléotides et analogues de ceux-ci |
| US20190169221A1 (en) | 2016-08-12 | 2019-06-06 | Janssen Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| WO2018081449A1 (en) | 2016-10-27 | 2018-05-03 | Alios Biopharma, Inc. | Methods for treating respiratory syncytial virus infection |
| CA3075950A1 (en) | 2017-09-18 | 2019-03-21 | Janssen Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
-
2015
- 2015-06-22 TN TN2016000566A patent/TN2016000566A1/en unknown
- 2015-06-22 NZ NZ727582A patent/NZ727582A/en not_active IP Right Cessation
- 2015-06-22 AU AU2015280234A patent/AU2015280234B2/en not_active Ceased
- 2015-06-22 US US14/746,138 patent/US9603863B2/en active Active
- 2015-06-22 AP AP2016009653A patent/AP2016009653A0/en unknown
- 2015-06-22 JP JP2016575325A patent/JP6669675B2/ja not_active Expired - Fee Related
- 2015-06-22 MA MA040031A patent/MA40031A/fr unknown
- 2015-06-22 EA EA201692537A patent/EA201692537A1/ru unknown
- 2015-06-22 EP EP15810951.2A patent/EP3160475B1/en active Active
- 2015-06-22 CN CN201580045400.7A patent/CN106604734B/zh active Active
- 2015-06-22 SG SG11201610597QA patent/SG11201610597QA/en unknown
- 2015-06-22 MX MX2016017381A patent/MX2016017381A/es unknown
- 2015-06-22 CA CA2952959A patent/CA2952959C/en active Active
- 2015-06-22 WO PCT/US2015/036958 patent/WO2015200205A1/en not_active Ceased
- 2015-06-24 TW TW104120407A patent/TW201613613A/zh unknown
-
2016
- 2016-12-18 IL IL249627A patent/IL249627A0/en unknown
- 2016-12-21 PH PH12016502563A patent/PH12016502563A1/en unknown
-
2017
- 2017-02-08 US US15/427,964 patent/US10052342B2/en active Active
-
2018
- 2018-08-20 US US16/105,859 patent/US10780105B2/en active Active
-
2020
- 2020-08-24 US US17/001,512 patent/US11590155B2/en active Active
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