MX2016017382A - Metodos para preparar analogos de nucleotido sustituidos. - Google Patents
Metodos para preparar analogos de nucleotido sustituidos.Info
- Publication number
- MX2016017382A MX2016017382A MX2016017382A MX2016017382A MX2016017382A MX 2016017382 A MX2016017382 A MX 2016017382A MX 2016017382 A MX2016017382 A MX 2016017382A MX 2016017382 A MX2016017382 A MX 2016017382A MX 2016017382 A MX2016017382 A MX 2016017382A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- nucleotide analogs
- preparing substituted
- substituted nucleotide
- preparing
- Prior art date
Links
- 125000003729 nucleotide group Chemical group 0.000 title 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- PTMHPRAIXMAOOB-UHFFFAOYSA-N phosphoramidic acid Chemical class NP(O)(O)=O PTMHPRAIXMAOOB-UHFFFAOYSA-N 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
- C07H1/02—Phosphorylation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
Se describen aquí métodos para preparar un análogo de nucleótido de fosforoamidato que son útiles al tratar enfermedades y/o condiciones tal como infecciones virales.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462016229P | 2014-06-24 | 2014-06-24 | |
| PCT/US2015/036989 WO2015200216A1 (en) | 2014-06-24 | 2015-06-22 | Methods of preparing substituted nucleotide analogs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2016017382A true MX2016017382A (es) | 2017-04-27 |
Family
ID=54869042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016017382A MX2016017382A (es) | 2014-06-24 | 2015-06-22 | Metodos para preparar analogos de nucleotido sustituidos. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20150368286A1 (es) |
| EP (1) | EP3160979A4 (es) |
| JP (1) | JP2017519779A (es) |
| KR (1) | KR20170026494A (es) |
| CN (1) | CN106661076A (es) |
| AU (1) | AU2015280245A1 (es) |
| BR (1) | BR112016029994A2 (es) |
| CA (1) | CA2952812A1 (es) |
| CL (1) | CL2016003277A1 (es) |
| EA (1) | EA201692473A1 (es) |
| IL (1) | IL249456A0 (es) |
| MX (1) | MX2016017382A (es) |
| NZ (1) | NZ727392A (es) |
| PH (1) | PH12016502555A1 (es) |
| SG (1) | SG11201610259SA (es) |
| TW (1) | TW201625659A (es) |
| WO (1) | WO2015200216A1 (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201610936RA (en) | 2011-12-22 | 2017-02-27 | Alios Biopharma Inc | Substituted nucleosides, nucleotides and analogs thereof |
| US8980865B2 (en) | 2011-12-22 | 2015-03-17 | Alios Biopharma, Inc. | Substituted nucleotide analogs |
| USRE48171E1 (en) | 2012-03-21 | 2020-08-25 | Janssen Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| US8916538B2 (en) | 2012-03-21 | 2014-12-23 | Vertex Pharmaceuticals Incorporated | Solid forms of a thiophosphoramidate nucleotide prodrug |
| US9441007B2 (en) | 2012-03-21 | 2016-09-13 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| WO2014100498A1 (en) | 2012-12-21 | 2014-06-26 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| WO2014165704A1 (en) | 2013-04-05 | 2014-10-09 | Vertex Pharmaceuticals, Inc. | Hepatitis c viral infection treatment using a combination of compounds |
| US9815864B2 (en) | 2013-06-26 | 2017-11-14 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| EP3424938B1 (en) | 2013-06-26 | 2020-07-22 | Janssen BioPharma, Inc. | 4'-azidoalkyl-substituted nucleosides, nucleotides and analogs thereof |
| AU2014331863C1 (en) | 2013-10-11 | 2019-05-16 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| AU2015280234B2 (en) | 2014-06-24 | 2021-04-01 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| CN117379452A (zh) | 2014-06-24 | 2024-01-12 | 艾丽奥斯生物制药有限公司 | 取代的核苷、核苷酸和其类似物 |
| US9908914B2 (en) | 2014-10-28 | 2018-03-06 | Alios Biopharma, Inc. | Methods of preparing substituted nucleoside analogs |
| MA41213A (fr) | 2014-12-19 | 2017-10-24 | Alios Biopharma Inc | Nucléosides substitués, nucléotides et analogues de ceux-ci |
| MA41441A (fr) | 2014-12-19 | 2017-12-12 | Alios Biopharma Inc | Nucléosides substitués, nucléotides et analogues de ceux-ci |
| MX383931B (es) | 2015-03-11 | 2025-03-14 | Janssen Biopharma Inc | Compuestos de aza-piridona y usos de estos. |
| WO2019237297A1 (en) * | 2018-06-14 | 2019-12-19 | Janssen Pharmaceuticals, Inc. | Processes for preparing compounds/intermediates useful in the treatment of viral infections |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3817978A (en) * | 1971-06-16 | 1974-06-18 | Syntex Inc | 4-fluoro nucleosides and sugar intermediates, and methods of preparing |
| GEP20176800B (en) * | 2012-05-22 | 2018-01-10 | Idenix Pharmaceuticals Llk | D-amino acid compounds for liver disease |
| CN110684067A (zh) * | 2012-12-21 | 2020-01-14 | 艾丽奥斯生物制药有限公司 | 取代的核苷和核苷酸 |
| MY186547A (en) * | 2013-05-16 | 2021-07-26 | Riboscience Llc | 4?-fluoro-2?-methyl substituted nucleoside derivatives |
| US9815864B2 (en) * | 2013-06-26 | 2017-11-14 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| AU2014331863C1 (en) * | 2013-10-11 | 2019-05-16 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| US9908914B2 (en) * | 2014-10-28 | 2018-03-06 | Alios Biopharma, Inc. | Methods of preparing substituted nucleoside analogs |
| MA41441A (fr) * | 2014-12-19 | 2017-12-12 | Alios Biopharma Inc | Nucléosides substitués, nucléotides et analogues de ceux-ci |
-
2015
- 2015-06-22 EA EA201692473A patent/EA201692473A1/ru unknown
- 2015-06-22 CA CA2952812A patent/CA2952812A1/en not_active Abandoned
- 2015-06-22 CN CN201580044596.8A patent/CN106661076A/zh active Pending
- 2015-06-22 SG SG11201610259SA patent/SG11201610259SA/en unknown
- 2015-06-22 NZ NZ727392A patent/NZ727392A/en not_active IP Right Cessation
- 2015-06-22 JP JP2016575200A patent/JP2017519779A/ja not_active Withdrawn
- 2015-06-22 WO PCT/US2015/036989 patent/WO2015200216A1/en not_active Ceased
- 2015-06-22 BR BR112016029994A patent/BR112016029994A2/pt not_active IP Right Cessation
- 2015-06-22 EP EP15812727.4A patent/EP3160979A4/en not_active Withdrawn
- 2015-06-22 AU AU2015280245A patent/AU2015280245A1/en not_active Abandoned
- 2015-06-22 MX MX2016017382A patent/MX2016017382A/es unknown
- 2015-06-22 US US14/746,219 patent/US20150368286A1/en not_active Abandoned
- 2015-06-22 KR KR1020177001916A patent/KR20170026494A/ko not_active Withdrawn
- 2015-06-24 TW TW104120378A patent/TW201625659A/zh unknown
-
2016
- 2016-12-08 IL IL249456A patent/IL249456A0/en unknown
- 2016-12-20 PH PH12016502555A patent/PH12016502555A1/en unknown
- 2016-12-21 CL CL2016003277A patent/CL2016003277A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PH12016502555A1 (en) | 2017-04-10 |
| TW201625659A (zh) | 2016-07-16 |
| CA2952812A1 (en) | 2015-12-30 |
| JP2017519779A (ja) | 2017-07-20 |
| EP3160979A1 (en) | 2017-05-03 |
| CN106661076A (zh) | 2017-05-10 |
| US20150368286A1 (en) | 2015-12-24 |
| BR112016029994A2 (pt) | 2017-08-22 |
| IL249456A0 (en) | 2017-02-28 |
| EA201692473A1 (ru) | 2017-03-31 |
| SG11201610259SA (en) | 2017-01-27 |
| CL2016003277A1 (es) | 2017-06-02 |
| KR20170026494A (ko) | 2017-03-08 |
| NZ727392A (en) | 2018-04-27 |
| EP3160979A4 (en) | 2018-01-03 |
| WO2015200216A1 (en) | 2015-12-30 |
| AU2015280245A1 (en) | 2017-01-05 |
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