JP2017516796A5 - - Google Patents
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- Publication number
- JP2017516796A5 JP2017516796A5 JP2016569766A JP2016569766A JP2017516796A5 JP 2017516796 A5 JP2017516796 A5 JP 2017516796A5 JP 2016569766 A JP2016569766 A JP 2016569766A JP 2016569766 A JP2016569766 A JP 2016569766A JP 2017516796 A5 JP2017516796 A5 JP 2017516796A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- methylphenyl
- methylpiperazin
- chloro
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2014/000540 | 2014-05-28 | ||
| CN2014000540 | 2014-05-28 | ||
| PCT/CN2015/079753 WO2015180612A1 (en) | 2014-05-28 | 2015-05-26 | Novel compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017516796A JP2017516796A (ja) | 2017-06-22 |
| JP2017516796A5 true JP2017516796A5 (enExample) | 2018-07-05 |
| JP6759110B2 JP6759110B2 (ja) | 2020-09-23 |
Family
ID=54698093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016569766A Expired - Fee Related JP6759110B2 (ja) | 2014-05-28 | 2015-05-26 | 新規な化合物 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9902735B2 (enExample) |
| EP (1) | EP3148975B1 (enExample) |
| JP (1) | JP6759110B2 (enExample) |
| KR (1) | KR20170012389A (enExample) |
| CN (1) | CN106536489B (enExample) |
| AU (1) | AU2015267909B2 (enExample) |
| BR (1) | BR112016027732B1 (enExample) |
| CA (1) | CA2950211C (enExample) |
| ES (1) | ES2710487T3 (enExample) |
| MX (1) | MX378098B (enExample) |
| RU (1) | RU2016150535A (enExample) |
| WO (1) | WO2015180612A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2928885T1 (sl) | 2012-12-06 | 2017-06-30 | Glaxo Group Limited | Modulatorji retinoidnemu sorodnega receptorja gama sirote (ror-gama) za uporabo pri zdravljenju avtoimunskih in vnetnih bolezni |
| ES2716966T3 (es) | 2014-05-28 | 2019-06-18 | Glaxosmithkline Ip Dev Ltd | Derivados de piperazina como moduladores de ROR-gamma |
| WO2015180613A1 (en) | 2014-05-28 | 2015-12-03 | Glaxosmithkline Intellectual Property Development Limited | Novel compounds |
| US20190175616A1 (en) * | 2016-06-23 | 2019-06-13 | Kessler Foundation Inc. | Testosterone replacement therapy in combination with neuromuscular stimulation |
| RU2771280C2 (ru) * | 2016-07-13 | 2022-04-29 | Лео Фарма А/С | Гетероароматические модуляторы ретинол-связанного орфанного рецептора гамма |
| AU2017379024B2 (en) | 2016-12-21 | 2021-03-04 | Jiangsu Hengrui Medicine Co., Ltd. | Condensed ring group azacyclobutyl triazole derivative, preparation method therefor and use thereof in medicine |
| TW201823231A (zh) | 2016-12-28 | 2018-07-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | 氮雜雙環基取代的三唑類衍生物、其製備方法及其在醫藥上的應用 |
| CN109134476B (zh) * | 2017-06-15 | 2021-03-19 | 复旦大学 | 桥环哌嗪类衍生物或其盐及其制备方法和用途 |
| JPWO2019022223A1 (ja) * | 2017-07-28 | 2020-06-11 | 東レ株式会社 | 環状アミン誘導体及びその医薬用途 |
| CN107698462A (zh) * | 2017-10-10 | 2018-02-16 | 重庆科脉生物化工有限公司 | 一种1‑氨基‑1‑环丙腈盐酸盐的制备方法 |
| CN109438423A (zh) * | 2018-09-12 | 2019-03-08 | 通化师范学院 | 一种肺癌靶向化合物azd-3759的合成工艺的新方法 |
| WO2021177431A1 (ja) * | 2020-03-06 | 2021-09-10 | 日産化学株式会社 | 新規触媒組成物並びに窒素含有基を有する炭素材料 |
| US20230219942A1 (en) * | 2020-06-09 | 2023-07-13 | Relive Therapeutics Inc. | Compounds comprising a three ring core as pd-1/pd-l1 blockers |
| CN116239445B (zh) * | 2023-01-05 | 2024-10-18 | 万华化学集团股份有限公司 | 一种丙内酯开环加氢合成1,3-丙二醇的方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000502100A (ja) * | 1995-12-18 | 2000-02-22 | 藤沢薬品工業株式会社 | タキキニン拮抗薬としてのピペラジン誘導体 |
| US7790726B2 (en) | 2005-08-16 | 2010-09-07 | Chemocentryx, Inc. | Monocyclic and bicyclic compounds and methods of use |
| US7825120B2 (en) | 2005-12-15 | 2010-11-02 | Cytokinetics, Inc. | Certain substituted ((piperazin-1-ylmethyl)benzyl)ureas |
| US20070208000A1 (en) | 2005-12-15 | 2007-09-06 | Morgan Bradley P | Certain chemical entities, compositions and methods |
| WO2007078839A2 (en) | 2005-12-19 | 2007-07-12 | Cytokinetics, Inc. | Compounds, compositions and methods |
| WO2012028100A1 (en) | 2010-09-01 | 2012-03-08 | Glaxo Group Limited | Novel compounds |
| WO2012027965A1 (en) * | 2010-09-01 | 2012-03-08 | Glaxo Group Limited | Novel compounds |
| WO2012100734A1 (en) | 2011-01-24 | 2012-08-02 | Glaxo Group Limited | Compounds useful as retinoid-related orphan receptor gamma modulators |
| WO2012100732A1 (en) | 2011-01-24 | 2012-08-02 | Glaxo Group Limited | Retinoid-related orphan receptor gamma modulators, composition containing them and uses thereof |
| EP2511263A1 (en) * | 2011-04-14 | 2012-10-17 | Phenex Pharmaceuticals AG | Pyrrolo sulfonamide compounds for modulation of orphan nuclear receptor RAR-related orphan receptor-gamma (RORgamma, NR1F3) activity and for the treatment of chronic inflammatory and autoimmune diseases |
| WO2012145254A2 (en) | 2011-04-16 | 2012-10-26 | Board Of Regents, The University Of Texas System | Methods of using inhibitors of rorϒt to treat disease |
| WO2012147916A1 (ja) | 2011-04-28 | 2012-11-01 | 日本たばこ産業株式会社 | アミド化合物およびその医薬用途 |
| WO2012158784A2 (en) * | 2011-05-16 | 2012-11-22 | Theodore Mark Kamenecka | Modulators of the nuclear hormone receptor ror |
| SG11201400456RA (en) | 2011-09-09 | 2014-04-28 | Univ New York | Amido compounds as ror?tmodulators and uses thereof |
| GB201116641D0 (en) | 2011-09-27 | 2011-11-09 | Glaxo Group Ltd | Novel compounds |
| PE20142400A1 (es) | 2012-04-27 | 2015-02-04 | Glaxo Group Ltd | Compuestos novedosos |
| GB201207406D0 (en) | 2012-04-27 | 2012-06-13 | Glaxo Group Ltd | Novel compounds |
| SI2928885T1 (sl) | 2012-12-06 | 2017-06-30 | Glaxo Group Limited | Modulatorji retinoidnemu sorodnega receptorja gama sirote (ror-gama) za uporabo pri zdravljenju avtoimunskih in vnetnih bolezni |
| WO2013171729A2 (en) | 2013-01-08 | 2013-11-21 | Glenmark Pharmaceuticals S.A. | Aryl and heteroaryl amide compounds as rorgamat modulator |
| WO2015061686A2 (en) | 2013-10-25 | 2015-04-30 | St. Jude Children's Research Hospital, Inc. | Retinoid x receptor-gamma agonists and retinoid x receptor-alpha antagonists for treatment of cancer |
| KR20160068799A (ko) | 2013-10-25 | 2016-06-15 | 글락소스미스클라인 엘엘씨 | 신규 화합물 |
| ES2716966T3 (es) | 2014-05-28 | 2019-06-18 | Glaxosmithkline Ip Dev Ltd | Derivados de piperazina como moduladores de ROR-gamma |
| WO2015180613A1 (en) | 2014-05-28 | 2015-12-03 | Glaxosmithkline Intellectual Property Development Limited | Novel compounds |
-
2015
- 2015-05-26 WO PCT/CN2015/079753 patent/WO2015180612A1/en not_active Ceased
- 2015-05-26 JP JP2016569766A patent/JP6759110B2/ja not_active Expired - Fee Related
- 2015-05-26 EP EP15800398.8A patent/EP3148975B1/en active Active
- 2015-05-26 US US15/314,111 patent/US9902735B2/en not_active Expired - Fee Related
- 2015-05-26 CA CA2950211A patent/CA2950211C/en active Active
- 2015-05-26 MX MX2016015630A patent/MX378098B/es unknown
- 2015-05-26 AU AU2015267909A patent/AU2015267909B2/en not_active Ceased
- 2015-05-26 BR BR112016027732-5A patent/BR112016027732B1/pt not_active IP Right Cessation
- 2015-05-26 RU RU2016150535A patent/RU2016150535A/ru not_active Application Discontinuation
- 2015-05-26 KR KR1020167036017A patent/KR20170012389A/ko not_active Withdrawn
- 2015-05-26 ES ES15800398T patent/ES2710487T3/es active Active
- 2015-05-26 CN CN201580039564.9A patent/CN106536489B/zh not_active Expired - Fee Related
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