JP2017513864A5 - - Google Patents

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Publication number
JP2017513864A5
JP2017513864A5 JP2016563113A JP2016563113A JP2017513864A5 JP 2017513864 A5 JP2017513864 A5 JP 2017513864A5 JP 2016563113 A JP2016563113 A JP 2016563113A JP 2016563113 A JP2016563113 A JP 2016563113A JP 2017513864 A5 JP2017513864 A5 JP 2017513864A5
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JP
Japan
Prior art keywords
composition
channel activator
item
subject
ion channel
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2016563113A
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English (en)
Japanese (ja)
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JP2017513864A (ja
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Priority claimed from PCT/US2015/025811 external-priority patent/WO2015160843A1/en
Publication of JP2017513864A publication Critical patent/JP2017513864A/ja
Publication of JP2017513864A5 publication Critical patent/JP2017513864A5/ja
Pending legal-status Critical Current

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JP2016563113A 2014-04-14 2015-04-14 イオンチャネル活性化剤及び使用方法 Pending JP2017513864A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201461979349P 2014-04-14 2014-04-14
US61/979,349 2014-04-14
US201462073131P 2014-10-31 2014-10-31
US201462073258P 2014-10-31 2014-10-31
US62/073,131 2014-10-31
US62/073,258 2014-10-31
PCT/US2015/025811 WO2015160843A1 (en) 2014-04-14 2015-04-14 Ion channel activators and methods of use

Publications (2)

Publication Number Publication Date
JP2017513864A JP2017513864A (ja) 2017-06-01
JP2017513864A5 true JP2017513864A5 (cg-RX-API-DMAC10.html) 2018-06-14

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Family Applications (1)

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JP2016563113A Pending JP2017513864A (ja) 2014-04-14 2015-04-14 イオンチャネル活性化剤及び使用方法

Country Status (14)

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US (2) US20170042834A1 (cg-RX-API-DMAC10.html)
EP (1) EP3131541A4 (cg-RX-API-DMAC10.html)
JP (1) JP2017513864A (cg-RX-API-DMAC10.html)
KR (1) KR20160143792A (cg-RX-API-DMAC10.html)
CN (1) CN106232110A (cg-RX-API-DMAC10.html)
AU (1) AU2015247815A1 (cg-RX-API-DMAC10.html)
BR (1) BR112016024034A2 (cg-RX-API-DMAC10.html)
CA (1) CA2945795A1 (cg-RX-API-DMAC10.html)
EA (1) EA201692060A1 (cg-RX-API-DMAC10.html)
IL (1) IL248339A0 (cg-RX-API-DMAC10.html)
MX (1) MX2016013486A (cg-RX-API-DMAC10.html)
SG (1) SG11201608383WA (cg-RX-API-DMAC10.html)
WO (1) WO2015160843A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201606684B (cg-RX-API-DMAC10.html)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6907884B2 (en) 2002-09-30 2005-06-21 Depay Acromed, Inc. Method of straddling an intraosseous nerve
US7258690B2 (en) 2003-03-28 2007-08-21 Relievant Medsystems, Inc. Windowed thermal ablation probe
US8361067B2 (en) 2002-09-30 2013-01-29 Relievant Medsystems, Inc. Methods of therapeutically heating a vertebral body to treat back pain
US10028753B2 (en) 2008-09-26 2018-07-24 Relievant Medsystems, Inc. Spine treatment kits
CA2737374C (en) 2008-09-26 2017-03-28 Relievant Medsystems, Inc. Systems and methods for navigating an instrument through bone
US10390877B2 (en) 2011-12-30 2019-08-27 Relievant Medsystems, Inc. Systems and methods for treating back pain
US10588691B2 (en) 2012-09-12 2020-03-17 Relievant Medsystems, Inc. Radiofrequency ablation of tissue within a vertebral body
KR101748053B1 (ko) 2012-10-17 2017-06-15 메틸레이션 사이언시즈 인터내셔널 에스알엘 S-아데노실메티오닌 및 갈산 에스테르가 포함된 조성물
IL238516B (en) 2012-11-05 2022-08-01 Relievant Medsystems Inc System and methods for creating curved pathways through bone and regulating the nerves within the bone
US9724151B2 (en) 2013-08-08 2017-08-08 Relievant Medsystems, Inc. Modulating nerves within bone using bone fasteners
WO2016170501A1 (en) * 2015-04-24 2016-10-27 Consiglio Nazionale Delle Ricerche A new therapeutic use of the botulinum neurotoxin serotype a
AU2016336544A1 (en) * 2015-10-06 2018-04-26 Flex Pharma, Inc. Methods and compositions for unwanted or abnormal muscle contractions
WO2017160156A1 (en) * 2016-03-18 2017-09-21 Axichem Ab Synthetic capasaicin analogs as trpv1 agonists
NO341559B1 (en) * 2016-03-18 2017-12-04 Axichem Ab Synthetic capsaicinoid derivatives and feed comprising such compounds as growth promotors
WO2017218697A1 (en) * 2016-06-17 2017-12-21 The Trustees Columbia University In The City Of New York Identification of compounds that target the rna-binding protein tia-1 an important regulator of stress vulnerability in both mice and humans
US11000490B2 (en) 2016-11-02 2021-05-11 Centrexion Therapeutics Corporation Stable aqueous capsaicin injectable formulations and medical uses thereof
CN106619585B (zh) * 2016-11-24 2019-03-01 中国人民解放军第四军医大学 肉桂醛及其衍生物在制备防治肺纤维化的药物中的应用
US10918685B2 (en) * 2017-01-05 2021-02-16 Ravi Ramamoorthy Iyer Herbal topical composition for muscle and joint health, recovery from exertion, and for pain management
US11253493B2 (en) 2017-01-23 2022-02-22 Cliff-Cartwright Corporation Compositions and methods affecting exercise performance
JP2020506207A (ja) * 2017-02-09 2020-02-27 ボード オブ リージェンツ オブ ザ ユニバーシティ オブ ネブラスカ 末梢動脈疾患の治療のための組成物および方法
WO2019018769A1 (en) 2017-07-20 2019-01-24 Centrexion Therapeutics Corporation METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN USING CAPSAICINE
US11554104B2 (en) * 2017-08-18 2023-01-17 The Schepens Eye Research Institute, Inc. Compositions for the treatment of dry eye and methods of use thereof
US12138274B2 (en) 2018-11-08 2024-11-12 Board Of Regents Of The University Of Nebraska Compositions and methods for the treatment of peripheral artery disease and cardiopulmonary diseases
CN113490745A (zh) * 2018-12-21 2021-10-08 索伦托药业有限公司 神经周施用树脂毒素治疗适应不良性疼痛
US11447444B1 (en) 2019-01-18 2022-09-20 Centrexion Therapeutics Corporation Capsaicinoid prodrug compounds and their use in treating medical conditions
US11254659B1 (en) 2019-01-18 2022-02-22 Centrexion Therapeutics Corporation Capsaicinoid prodrug compounds and their use in treating medical conditions
JP7177738B2 (ja) * 2019-03-26 2022-11-24 サントリーホールディングス株式会社 リナロール含有飲料
WO2020241754A1 (ja) * 2019-05-31 2020-12-03 サントリーホールディングス株式会社 ノンアルコールビールテイスト飲料
CA3143042A1 (en) * 2019-06-11 2020-12-17 Pano Therapeutics, Inc. Capsaicin and trpv1 modulator combinations and methods of use thereof
EP3753417A1 (en) 2019-06-20 2020-12-23 PerformaNat GmbH Feed additive
US11707437B2 (en) * 2019-07-12 2023-07-25 Board Of Trustees Of Southern Illinois University Topical formulations with resiniferatoxin nanoparticles and methods
AU2020346827B2 (en) 2019-09-12 2026-03-12 Relievant Medsystems, Inc. Systems and methods for tissue modulation
PH12022550262A1 (en) * 2019-09-23 2022-11-21 Unilever Ip Holdings B V Oil-in-water emulsion comprising plant protein
CN110664990B (zh) * 2019-11-07 2021-03-16 江南大学 一种trpc1肽类分子在制备治疗病毒感染引起的炎症的药物中的应用
KR102303624B1 (ko) * 2020-01-22 2021-09-16 한국식품연구원 머위잎 추출물을 유효성분으로 포함하는 근육 질환 예방, 개선 또는 치료용 조성물
WO2021168463A1 (en) * 2020-02-21 2021-08-26 Douglas Thomas Buccal and enteric delivery of fatty acids in foods and beverages
US20230143545A1 (en) * 2020-03-30 2023-05-11 Board Of Regents Of The University Of Nebraska Treating Pulmonary Inflammatory Disease Associated With Covid-19 By Administering Resiniferatoxin
AU2021306313B2 (en) 2020-07-10 2026-07-09 Relievant Medsystems, Inc. Vertebral denervation in conjunction with vertebral fusion
US12082876B1 (en) 2020-09-28 2024-09-10 Relievant Medsystems, Inc. Introducer drill
JP7878625B2 (ja) * 2020-11-16 2026-06-23 ハウスウェルネスフーズ株式会社 アドレノメデュリン遺伝子発現増強用組成物
AU2021409967A1 (en) 2020-12-22 2023-08-03 Relievant Medsystems, Inc. Prediction of candidates for spinal neuromodulation
US20240299348A1 (en) * 2021-01-08 2024-09-12 Caraway Therapeutics, Inc. Modulators of trpml, their compositions and methods of use
US20240099998A1 (en) * 2021-01-15 2024-03-28 Dignify Therapeutics, Llc Compositions and methods for inducing defecation
CN113243338A (zh) * 2021-05-14 2021-08-13 福州大学 一种小鼠缺血性卒中模型的构建与评估方法
CA3221865A1 (en) 2021-06-07 2022-12-15 Nodari RIZUN Enriched mineral pitch resin products and methods of manufacturing enriched mineral pitch resin products
JP2023010677A (ja) * 2021-07-09 2023-01-20 株式会社東洋新薬 固形組成物
US12433668B1 (en) 2021-11-08 2025-10-07 Relievant Medsystems, Inc. Impedance stoppage mitigation during radiofrequency tissue ablation procedures
US20240423952A1 (en) * 2021-11-15 2024-12-26 Ibagen Pharmaceuticals, Inc. Compositions and methods for treating congenital disorders
JP7825975B2 (ja) * 2021-11-16 2026-03-09 ハウスウェルネスフーズ株式会社 アドレノメデュリン遺伝子発現増強用組成物
CN119013010A (zh) * 2021-12-16 2024-11-22 艾维尔勒斯生物公司 用于治疗慢性肺病的可吸入或可摄入的乳酸组合物
CN115006342A (zh) * 2022-04-14 2022-09-06 辽宁天融生物科技有限公司 一种抗高尿酸活性组分及其应用方法
CN114869869B (zh) * 2022-04-21 2023-09-19 北京积水潭医院 Eugenol在预防和/或治疗骨关节炎中的应用
CN115444845B (zh) * 2022-08-05 2023-07-21 四川大学华西医院 一种促进伤口愈合的组合物和智能涂层材料
CN115844049B (zh) * 2022-11-21 2024-12-10 深圳市真味生物科技有限公司 一种不添加烟碱的薄荷烟草电子雾化液及其制备方法
WO2024118705A1 (en) * 2022-11-29 2024-06-06 Neuro-Innovators, Llc Neurorestoration compound implementing multiple neuroplasticity inducing mechanisms of action
JP2026500538A (ja) * 2022-12-23 2026-01-07 デブレツェン エジェテム H2s放出化合物を用いたミエロペルオキシダーゼ陽性anca関連血管炎の処置
JP2024159343A (ja) * 2023-04-28 2024-11-08 住友化学株式会社 昆虫細胞を拡大培養する方法
EP4712796A2 (en) * 2023-05-15 2026-03-25 Bonafide Health, LLC Sleep-improving compositions and methods of use
CN116891523B (zh) * 2023-05-24 2024-05-17 深圳晶蛋生物医药科技有限公司 一种trpm3截短体、包含其的细胞系及其用途
WO2025024655A1 (en) * 2023-07-25 2025-01-30 Balance Lytes, Llc Urea compositions and methods of use

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09176002A (ja) * 1995-12-27 1997-07-08 Kureha Chem Ind Co Ltd Hsp27ファミリーに属するタンパク質のジンゲロール含有合成抑制剤
ATE285769T1 (de) * 1998-12-04 2005-01-15 Neurosearch As Verwendung von isatinderivaten als ionenkanalaktivierende mittel
US6592896B2 (en) * 2001-08-06 2003-07-15 The Quigley Corporation Medicinal composition and method of using it
BRPI0513465B1 (pt) * 2004-08-11 2015-08-11 Intercontinental Great Brands Llc Composições orais, artigo comestível, composições para balas e goma de mascar, métodos para preparação do referido artigo e para fornercer sensação às áreas receptoras orais
CN101001537B (zh) * 2004-08-11 2013-12-18 卡夫食品全球品牌有限责任公司 感觉剂组合物和它的输送体系
WO2007044748A2 (en) * 2005-10-11 2007-04-19 University Of Pittsburgh Sphingomyelin liposomes for the treatment of hyperactive bladder disorders
US20080021034A1 (en) * 2006-04-10 2008-01-24 Painceptor Pharma Corporation Compositions and methods for modulating gated ion channels
CN102112121A (zh) * 2008-03-11 2011-06-29 哈佛大学校长及研究员协会 用于治疗疼痛和瘙痒的方法、组合物和药盒
US20090304827A1 (en) * 2008-05-08 2009-12-10 Kim Darrick S H L Combinations of Ingredients Having Synergistic Anti-Inflammatory Effects
PL2629610T3 (pl) * 2010-07-27 2018-02-28 Flex Pharma, Inc. Sposoby i kompozycje do zapobiegania i zmniejszania kurczy mięśni i do regeneracji po nerwowo-mięśniowym podrażnieniu i zmęczeniu po ćwiczeniach fizycznych
US9211274B2 (en) * 2012-02-01 2015-12-15 Warsaw Orthopedic, Inc. TRPV1 compounds in a biodegradable polymer carrier
WO2013155365A1 (en) * 2012-04-12 2013-10-17 University Of Maryland Markers for diagnosing amyotrophic lateral sclerosis
BR112015017176A2 (pt) * 2013-01-18 2017-07-11 Tonix Pharmaceuticals Inc isômero isometepteno

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