JP2017510575A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017510575A5 JP2017510575A5 JP2016558161A JP2016558161A JP2017510575A5 JP 2017510575 A5 JP2017510575 A5 JP 2017510575A5 JP 2016558161 A JP2016558161 A JP 2016558161A JP 2016558161 A JP2016558161 A JP 2016558161A JP 2017510575 A5 JP2017510575 A5 JP 2017510575A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sequence
- fusion polypeptide
- disease
- syndrome
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461954437P | 2014-03-17 | 2014-03-17 | |
| US61/954,437 | 2014-03-17 | ||
| PCT/JP2015/058645 WO2015141862A1 (en) | 2014-03-17 | 2015-03-16 | Antibody-fynomer conjugates |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017510575A JP2017510575A (ja) | 2017-04-13 |
| JP2017510575A5 true JP2017510575A5 (enExample) | 2017-08-10 |
| JP6345800B2 JP6345800B2 (ja) | 2018-06-20 |
Family
ID=54144822
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016558161A Active JP6345800B2 (ja) | 2014-03-17 | 2015-03-16 | 抗体−フィノマー複合体 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US10323095B2 (enExample) |
| EP (1) | EP3119885B1 (enExample) |
| JP (1) | JP6345800B2 (enExample) |
| KR (1) | KR102473544B1 (enExample) |
| CN (1) | CN106211782B (enExample) |
| AU (1) | AU2015232352B2 (enExample) |
| CA (1) | CA2942546C (enExample) |
| DK (1) | DK3119885T3 (enExample) |
| ES (1) | ES2881602T3 (enExample) |
| HU (1) | HUE055424T2 (enExample) |
| MX (1) | MX374483B (enExample) |
| PH (1) | PH12016501816B1 (enExample) |
| PL (1) | PL3119885T3 (enExample) |
| PT (1) | PT3119885T (enExample) |
| RU (1) | RU2732226C2 (enExample) |
| TW (1) | TWI674274B (enExample) |
| WO (1) | WO2015141862A1 (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11566082B2 (en) | 2014-11-17 | 2023-01-31 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| US10654887B2 (en) | 2016-05-11 | 2020-05-19 | Ge Healthcare Bio-Process R&D Ab | Separation matrix |
| JP7106187B2 (ja) | 2016-05-11 | 2022-07-26 | サイティバ・バイオプロセス・アールアンドディ・アクチボラグ | 分離マトリックスを保存する方法 |
| ES2909833T3 (es) | 2016-05-11 | 2022-05-10 | Cytiva Bioprocess R & D Ab | Método de limpieza y/o desinfección de una matriz de separación |
| US10889615B2 (en) | 2016-05-11 | 2021-01-12 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| JP7031934B2 (ja) | 2016-05-11 | 2022-03-08 | サイティバ・バイオプロセス・アールアンドディ・アクチボラグ | 分離マトリックス |
| ES2874974T3 (es) | 2016-05-11 | 2021-11-05 | Cytiva Bioprocess R & D Ab | Matriz de separación |
| US10730908B2 (en) | 2016-05-11 | 2020-08-04 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| US10703774B2 (en) | 2016-09-30 | 2020-07-07 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| US12448411B2 (en) | 2016-09-30 | 2025-10-21 | Cytiva Bioprocess R&D Ab | Separation method |
| US20200087390A1 (en) | 2016-12-21 | 2020-03-19 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| US10722589B2 (en) | 2017-04-03 | 2020-07-28 | Covagen Ag | FGFR3 binding molecules |
| US20190153096A1 (en) | 2017-10-02 | 2019-05-23 | Covagen Ag | Cd3/cd33 bispecific binding molecules |
| US20190100587A1 (en) | 2017-10-02 | 2019-04-04 | Covagen Ag | IgG1 Fc MUTANTS WITH ABLATED EFFECTOR FUNCTIONS |
| KR20210070307A (ko) * | 2018-10-02 | 2021-06-14 | 미쓰비시 타나베 파마 코퍼레이션 | 신데칸-1 및 섬유아세포 성장 인자 수용체를 표적화하는 이중특이적 결합제 |
| CN113166246B (zh) | 2018-12-28 | 2024-10-18 | 四川科伦博泰生物医药股份有限公司 | 一种抗体及其用途 |
| WO2020211674A1 (zh) | 2019-04-16 | 2020-10-22 | 四川科伦博泰生物医药股份有限公司 | 抗FXI/FXIa抗体及其用途 |
| KR20220070201A (ko) | 2019-09-30 | 2022-05-30 | 쓰촨 케룬-바이오테크 바이오파마수티컬 컴퍼니 리미티드 | 항-pd-1 항체 및 이의 용도 |
| CA3155759A1 (en) | 2019-12-13 | 2021-06-17 | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Anti-tslp antibody and uses thereof |
| IL298184A (en) | 2020-05-15 | 2023-01-01 | Sichuan Kelun Biotech Biopharmaceutical Co Ltd | Antibody drug conjugate, preparation method therefor and use thereof |
| AU2021372706A1 (en) | 2020-10-26 | 2023-06-08 | Akeso Biopharma, Inc. | Anti-tigit antibody, and pharmaceutical composition and use thereof |
| JP7691668B2 (ja) | 2020-12-31 | 2025-06-12 | 諾納生物（蘇州）有限公司 | ヒトｌｉｆｒ抗原結合タンパク質、その製造方法及び応用 |
| WO2022157493A1 (en) | 2021-01-21 | 2022-07-28 | Eusa Pharma (Uk) Limited | Method for treating il-6 associated histiocytic and lymphoproliferative disorders |
| EP4306540A4 (en) | 2021-03-09 | 2025-05-28 | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | ROR1-BINDING PROTEIN AND USE THEREOF |
| CN116059341A (zh) | 2021-07-23 | 2023-05-05 | 中山康方生物医药有限公司 | 药物组合物及用途 |
| EP4405396A2 (en) | 2021-09-20 | 2024-07-31 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of her2 positive cancer |
| US20250034559A1 (en) | 2021-11-17 | 2025-01-30 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of tau-related disorders |
| CN114181310B (zh) | 2022-02-14 | 2022-07-05 | 中山康方生物医药有限公司 | 抗tigit抗体、其药物组合物及用途 |
| CN114853890B (zh) | 2022-03-16 | 2023-04-28 | 沈阳三生制药有限责任公司 | 一种prlr抗原结合蛋白及其制备方法和应用 |
| CN116925222A (zh) | 2022-04-02 | 2023-10-24 | 普米斯生物技术(珠海)有限公司 | 抗pvrig抗体、其药物组合物及用途 |
| CN116925233A (zh) | 2022-04-02 | 2023-10-24 | 普米斯生物技术(珠海)有限公司 | 抗tigit-抗pvrig双特异性抗体、其药物组合物及用途 |
| EP4522757A2 (en) | 2022-05-13 | 2025-03-19 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of her2 positive cancer |
| WO2024228389A1 (ja) * | 2023-05-02 | 2024-11-07 | 田辺三菱製薬株式会社 | 対象における二重特異性融合ポリペプチドの有効性を予測するための方法 |
| IL326700A (en) * | 2023-09-11 | 2026-04-01 | Hoffmann La Roche | Multispecific fusion proteins targeting angiogenic and inflammatory factors |
| WO2025122634A1 (en) | 2023-12-05 | 2025-06-12 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of tau-related disorders |
| WO2025224095A1 (en) | 2024-04-22 | 2025-10-30 | Recordati Netherlands Bv | Use of inhibitors of il-6 or il-6r for treating graft versus host disease in a subject |
| PL448731A1 (pl) * | 2024-05-31 | 2025-12-01 | Celon Pharma Spółka Akcyjna | Przeciwciała bispecyficzne anty–IL-17A i anty-IL-6 oraz ich zastosowanie w terapii, zwłaszcza w leczeniu chorób immunologicznych |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| CN101874042B9 (zh) * | 2007-09-26 | 2019-01-01 | 中外制药株式会社 | 利用cdr的氨基酸取代来改变抗体等电点的方法 |
| CA2724279C (en) * | 2008-05-13 | 2017-03-07 | Novimmune S.A. | Anti-il-6/il-6r antibodies and methods of use thereof |
| EP3002299A1 (en) | 2008-06-03 | 2016-04-06 | AbbVie Inc. | Dual variable domain immunoglobulins and uses thereof |
| TWI440469B (zh) | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
| BR112012004314A2 (pt) * | 2009-08-27 | 2016-11-29 | Covagen Ag | compostos de ligação a il-17 e usos medicinais desses compostos |
| AR080428A1 (es) | 2010-01-20 | 2012-04-11 | Chugai Pharmaceutical Co Ltd | Formulaciones liquidas estabilizadas contentivas de anticuerpos |
| US8524217B2 (en) * | 2010-05-11 | 2013-09-03 | Merck Sharp & Dohme Corp. | MCP1-Ig fusion variants |
| EP2597102A1 (en) * | 2011-11-25 | 2013-05-29 | Covagen AG | A novel fusion protein comprising an antibody light chain and a polypeptide binding to IL-17 |
| EP2791171A1 (en) * | 2011-12-16 | 2014-10-22 | Synthon Biopharmaceuticals B.V. | EXPRESSION OF SECRETORY IgA ANTIBODIES IN DUCKWEED |
| KR20140135251A (ko) | 2012-03-16 | 2014-11-25 | 코바겐 아게 | 항종양 활성이 있는 신규 결합 분자 |
| EP2638916A1 (en) * | 2012-03-16 | 2013-09-18 | Covagen AG | Novel binding molecules with antitumoral activity |
| EP2711016A1 (en) | 2012-09-21 | 2014-03-26 | Covagen AG | Novel IL-17A binding molecules and medical uses thereof |
-
2015
- 2015-03-16 US US15/126,551 patent/US10323095B2/en active Active
- 2015-03-16 JP JP2016558161A patent/JP6345800B2/ja active Active
- 2015-03-16 EP EP15765900.4A patent/EP3119885B1/en active Active
- 2015-03-16 HU HUE15765900A patent/HUE055424T2/hu unknown
- 2015-03-16 DK DK15765900.4T patent/DK3119885T3/da active
- 2015-03-16 PT PT157659004T patent/PT3119885T/pt unknown
- 2015-03-16 KR KR1020167028719A patent/KR102473544B1/ko active Active
- 2015-03-16 TW TW104108275A patent/TWI674274B/zh active
- 2015-03-16 MX MX2016012010A patent/MX374483B/es active IP Right Grant
- 2015-03-16 CN CN201580014271.5A patent/CN106211782B/zh active Active
- 2015-03-16 ES ES15765900T patent/ES2881602T3/es active Active
- 2015-03-16 RU RU2016140572A patent/RU2732226C2/ru active
- 2015-03-16 CA CA2942546A patent/CA2942546C/en active Active
- 2015-03-16 PL PL15765900T patent/PL3119885T3/pl unknown
- 2015-03-16 AU AU2015232352A patent/AU2015232352B2/en active Active
- 2015-03-16 WO PCT/JP2015/058645 patent/WO2015141862A1/en not_active Ceased
-
2016
- 2016-09-16 PH PH12016501816A patent/PH12016501816B1/en unknown