JP2017510575A5 - - Google Patents
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- Publication number
- JP2017510575A5 JP2017510575A5 JP2016558161A JP2016558161A JP2017510575A5 JP 2017510575 A5 JP2017510575 A5 JP 2017510575A5 JP 2016558161 A JP2016558161 A JP 2016558161A JP 2016558161 A JP2016558161 A JP 2016558161A JP 2017510575 A5 JP2017510575 A5 JP 2017510575A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sequence
- fusion polypeptide
- disease
- syndrome
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461954437P | 2014-03-17 | 2014-03-17 | |
| US61/954,437 | 2014-03-17 | ||
| PCT/JP2015/058645 WO2015141862A1 (en) | 2014-03-17 | 2015-03-16 | Antibody-fynomer conjugates |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017510575A JP2017510575A (ja) | 2017-04-13 |
| JP2017510575A5 true JP2017510575A5 (enExample) | 2017-08-10 |
| JP6345800B2 JP6345800B2 (ja) | 2018-06-20 |
Family
ID=54144822
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016558161A Active JP6345800B2 (ja) | 2014-03-17 | 2015-03-16 | 抗体−フィノマー複合体 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US10323095B2 (enExample) |
| EP (1) | EP3119885B1 (enExample) |
| JP (1) | JP6345800B2 (enExample) |
| KR (1) | KR102473544B1 (enExample) |
| CN (1) | CN106211782B (enExample) |
| AU (1) | AU2015232352B2 (enExample) |
| CA (1) | CA2942546C (enExample) |
| DK (1) | DK3119885T3 (enExample) |
| ES (1) | ES2881602T3 (enExample) |
| HU (1) | HUE055424T2 (enExample) |
| MX (1) | MX374483B (enExample) |
| PH (1) | PH12016501816A1 (enExample) |
| PL (1) | PL3119885T3 (enExample) |
| PT (1) | PT3119885T (enExample) |
| RU (1) | RU2732226C2 (enExample) |
| TW (1) | TWI674274B (enExample) |
| WO (1) | WO2015141862A1 (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11566082B2 (en) | 2014-11-17 | 2023-01-31 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| US10889615B2 (en) | 2016-05-11 | 2021-01-12 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| ES2909833T3 (es) | 2016-05-11 | 2022-05-10 | Cytiva Bioprocess R & D Ab | Método de limpieza y/o desinfección de una matriz de separación |
| US10730908B2 (en) | 2016-05-11 | 2020-08-04 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| JP7031934B2 (ja) | 2016-05-11 | 2022-03-08 | サイティバ・バイオプロセス・アールアンドディ・アクチボラグ | 分離マトリックス |
| EP3455243B1 (en) | 2016-05-11 | 2021-03-24 | Cytiva BioProcess R&D AB | Separation matrix |
| US10654887B2 (en) | 2016-05-11 | 2020-05-19 | Ge Healthcare Bio-Process R&D Ab | Separation matrix |
| US10703774B2 (en) | 2016-09-30 | 2020-07-07 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| US11708390B2 (en) | 2016-05-11 | 2023-07-25 | Cytiva Bioprocess R&D Ab | Method of storing a separation matrix |
| US12448411B2 (en) | 2016-09-30 | 2025-10-21 | Cytiva Bioprocess R&D Ab | Separation method |
| EP3824906A1 (en) | 2016-12-21 | 2021-05-26 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| US10722589B2 (en) | 2017-04-03 | 2020-07-28 | Covagen Ag | FGFR3 binding molecules |
| US20190153096A1 (en) | 2017-10-02 | 2019-05-23 | Covagen Ag | Cd3/cd33 bispecific binding molecules |
| US20190100587A1 (en) | 2017-10-02 | 2019-04-04 | Covagen Ag | IgG1 Fc MUTANTS WITH ABLATED EFFECTOR FUNCTIONS |
| BR112021005465A2 (pt) * | 2018-10-02 | 2021-06-15 | Mitsubishi Tanabe Pharma Corporation | agentes de ligação biespecíficos direcionados ao sindecano-1 e receptor do fator de crescimento de fibroblasto |
| CN113166246B (zh) | 2018-12-28 | 2024-10-18 | 四川科伦博泰生物医药股份有限公司 | 一种抗体及其用途 |
| CN113474374B (zh) | 2019-04-16 | 2025-05-02 | 四川科伦博泰生物医药股份有限公司 | 抗FXI/FXIa抗体及其用途 |
| KR20220070201A (ko) | 2019-09-30 | 2022-05-30 | 쓰촨 케룬-바이오테크 바이오파마수티컬 컴퍼니 리미티드 | 항-pd-1 항체 및 이의 용도 |
| KR20220113673A (ko) | 2019-12-13 | 2022-08-16 | 쓰촨 케룬-바이오테크 바이오파마수티컬 컴퍼니 리미티드 | 항-tslp 항체 및 그 용도 |
| JP7407973B2 (ja) | 2020-05-15 | 2024-01-04 | シチュアン ケルン－バイオテック バイオファーマシューティカル カンパニー リミテッド | 抗体薬物複合体、その調製方法、およびその使用 |
| CA3194641A1 (en) | 2020-10-26 | 2022-05-05 | Akeso Biopharma, Inc. | Anti-tigit antibody, and pharmaceutical composition and use thereof |
| AU2021414160B2 (en) | 2020-12-31 | 2025-08-07 | Nona Biosciences (Suzhou) Co., Ltd. | Human lifr antigen binding protein, preparation method therefor, and application thereof |
| WO2022157493A1 (en) | 2021-01-21 | 2022-07-28 | Eusa Pharma (Uk) Limited | Method for treating il-6 associated histiocytic and lymphoproliferative disorders |
| WO2022188652A1 (zh) | 2021-03-09 | 2022-09-15 | 四川科伦博泰生物医药股份有限公司 | Ror1结合蛋白及其用途 |
| AU2022314097A1 (en) | 2021-07-23 | 2024-03-07 | Akeso Biopharma, Inc | Pharmaceutical composition and use |
| EP4405396A2 (en) | 2021-09-20 | 2024-07-31 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of her2 positive cancer |
| US20250034559A1 (en) | 2021-11-17 | 2025-01-30 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of tau-related disorders |
| CN114181310B (zh) | 2022-02-14 | 2022-07-05 | 中山康方生物医药有限公司 | 抗tigit抗体、其药物组合物及用途 |
| CN114853890B (zh) | 2022-03-16 | 2023-04-28 | 沈阳三生制药有限责任公司 | 一种prlr抗原结合蛋白及其制备方法和应用 |
| CN116925222A (zh) | 2022-04-02 | 2023-10-24 | 普米斯生物技术(珠海)有限公司 | 抗pvrig抗体、其药物组合物及用途 |
| CN116925233A (zh) | 2022-04-02 | 2023-10-24 | 普米斯生物技术(珠海)有限公司 | 抗tigit-抗pvrig双特异性抗体、其药物组合物及用途 |
| EP4522757A2 (en) | 2022-05-13 | 2025-03-19 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of her2 positive cancer |
| WO2024228389A1 (ja) * | 2023-05-02 | 2024-11-07 | 田辺三菱製薬株式会社 | 対象における二重特異性融合ポリペプチドの有効性を予測するための方法 |
| WO2025054768A1 (en) * | 2023-09-11 | 2025-03-20 | Eluminex Biosciences (Suzhou) Limited | Multispecific fusion proteins targeting angiogenic and inflammatory factors |
| WO2025122634A1 (en) | 2023-12-05 | 2025-06-12 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of tau-related disorders |
| WO2025224095A1 (en) | 2024-04-22 | 2025-10-30 | Recordati Netherlands Bv | Use of inhibitors of il-6 or il-6r for treating graft versus host disease in a subject |
| PL448731A1 (pl) * | 2024-05-31 | 2025-12-01 | Celon Pharma Spółka Akcyjna | Przeciwciała bispecyficzne anty–IL-17A i anty-IL-6 oraz ich zastosowanie w terapii, zwłaszcza w leczeniu chorób immunologicznych |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| DK2202245T3 (en) * | 2007-09-26 | 2016-11-21 | Chugai Pharmaceutical Co Ltd | A method of modifying an antibody isoelectric point VIA amino acid substitution in CDR |
| US8034344B2 (en) | 2008-05-13 | 2011-10-11 | Novimmune S.A. | Anti-IL-6/IL-6R antibodies and methods of use thereof |
| SG191639A1 (en) * | 2008-06-03 | 2013-07-31 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
| TWI440469B (zh) | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
| CA2772162C (en) * | 2009-08-27 | 2018-05-22 | Covagen Ag | Anti-il-17a fynomers and medical uses thereof |
| TWI505838B (zh) | 2010-01-20 | 2015-11-01 | Chugai Pharmaceutical Co Ltd | Stabilized antibody solution containing |
| US8524217B2 (en) | 2010-05-11 | 2013-09-03 | Merck Sharp & Dohme Corp. | MCP1-Ig fusion variants |
| EP2597102A1 (en) * | 2011-11-25 | 2013-05-29 | Covagen AG | A novel fusion protein comprising an antibody light chain and a polypeptide binding to IL-17 |
| WO2013087911A1 (en) | 2011-12-16 | 2013-06-20 | Synthon Biopharmaceuticals B.V. | Compounds and methods for treating inflammatory diseases |
| MX354717B (es) | 2012-03-16 | 2018-03-16 | Covagen Ag | Moleculas de union novedosas con actividad antitumoral. |
| EP2638916A1 (en) * | 2012-03-16 | 2013-09-18 | Covagen AG | Novel binding molecules with antitumoral activity |
| EP2711016A1 (en) * | 2012-09-21 | 2014-03-26 | Covagen AG | Novel IL-17A binding molecules and medical uses thereof |
-
2015
- 2015-03-16 HU HUE15765900A patent/HUE055424T2/hu unknown
- 2015-03-16 DK DK15765900.4T patent/DK3119885T3/da active
- 2015-03-16 CA CA2942546A patent/CA2942546C/en active Active
- 2015-03-16 AU AU2015232352A patent/AU2015232352B2/en active Active
- 2015-03-16 RU RU2016140572A patent/RU2732226C2/ru active
- 2015-03-16 JP JP2016558161A patent/JP6345800B2/ja active Active
- 2015-03-16 KR KR1020167028719A patent/KR102473544B1/ko active Active
- 2015-03-16 CN CN201580014271.5A patent/CN106211782B/zh active Active
- 2015-03-16 EP EP15765900.4A patent/EP3119885B1/en active Active
- 2015-03-16 US US15/126,551 patent/US10323095B2/en active Active
- 2015-03-16 MX MX2016012010A patent/MX374483B/es active IP Right Grant
- 2015-03-16 ES ES15765900T patent/ES2881602T3/es active Active
- 2015-03-16 WO PCT/JP2015/058645 patent/WO2015141862A1/en not_active Ceased
- 2015-03-16 PT PT157659004T patent/PT3119885T/pt unknown
- 2015-03-16 TW TW104108275A patent/TWI674274B/zh active
- 2015-03-16 PL PL15765900T patent/PL3119885T3/pl unknown
-
2016
- 2016-09-16 PH PH12016501816A patent/PH12016501816A1/en unknown
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