JP2017509350A - ガイドrnaの生成のための方法および組成物 - Google Patents
ガイドrnaの生成のための方法および組成物 Download PDFInfo
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- JP2017509350A JP2017509350A JP2016560684A JP2016560684A JP2017509350A JP 2017509350 A JP2017509350 A JP 2017509350A JP 2016560684 A JP2016560684 A JP 2016560684A JP 2016560684 A JP2016560684 A JP 2016560684A JP 2017509350 A JP2017509350 A JP 2017509350A
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- nucleotide sequence
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- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
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- C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
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- C12N2830/00—Vector systems having a special element relevant for transcription
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461974672P | 2014-04-03 | 2014-04-03 | |
| US61/974,672 | 2014-04-03 | ||
| PCT/US2015/024196 WO2015153940A1 (en) | 2014-04-03 | 2015-04-03 | Methods and compositions for the production of guide rna |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017509350A true JP2017509350A (ja) | 2017-04-06 |
| JP2017509350A5 JP2017509350A5 (cg-RX-API-DMAC7.html) | 2018-05-31 |
Family
ID=52997563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016560684A Pending JP2017509350A (ja) | 2014-04-03 | 2015-04-03 | ガイドrnaの生成のための方法および組成物 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20170022499A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3126503A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2017509350A (cg-RX-API-DMAC7.html) |
| CN (1) | CN106170550A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015153940A1 (cg-RX-API-DMAC7.html) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017502683A (ja) * | 2014-01-14 | 2017-01-26 | ラム セラピューティクス, インコーポレイテッド | 変異誘発方法 |
| JP2023532864A (ja) * | 2020-06-30 | 2023-08-01 | ザ ユニバーシティー コート オブ ザ ユニバーシティー オブ エジンバラ | 導入遺伝子発現系 |
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| CA2853829C (en) | 2011-07-22 | 2023-09-26 | President And Fellows Of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| WO2014204578A1 (en) | 2013-06-21 | 2014-12-24 | The General Hospital Corporation | Using rna-guided foki nucleases (rfns) to increase specificity for rna-guided genome editing |
| US10760064B2 (en) | 2013-03-15 | 2020-09-01 | The General Hospital Corporation | RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci |
| KR102874079B1 (ko) | 2013-03-15 | 2025-10-22 | 더 제너럴 하스피탈 코포레이션 | Rna-안내 게놈 편집을 위해 특이성을 증가시키기 위한 절단된 안내 rna(tru-grnas)의 이용 |
| US9163284B2 (en) | 2013-08-09 | 2015-10-20 | President And Fellows Of Harvard College | Methods for identifying a target site of a Cas9 nuclease |
| US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
| US9388430B2 (en) | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
| US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
| US9228207B2 (en) | 2013-09-06 | 2016-01-05 | President And Fellows Of Harvard College | Switchable gRNAs comprising aptamers |
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| EA201792663A1 (ru) | 2015-05-29 | 2018-04-30 | Норт Каролина Стейт Юниверсити | Способы скрининга бактерий, архей, водорослей и дрожжей с использованием нуклеиновых кислот crispr |
| US11155823B2 (en) | 2015-06-15 | 2021-10-26 | North Carolina State University | Methods and compositions for efficient delivery of nucleic acids and RNA-based antimicrobials |
| US9926546B2 (en) | 2015-08-28 | 2018-03-27 | The General Hospital Corporation | Engineered CRISPR-Cas9 nucleases |
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| EP3356533A1 (en) | 2015-09-28 | 2018-08-08 | North Carolina State University | Methods and compositions for sequence specific antimicrobials |
| SG11201803173VA (en) | 2015-10-23 | 2018-05-30 | Harvard College | Nucleobase editors and uses thereof |
| EP3390632B1 (en) * | 2015-12-18 | 2025-09-10 | Danisco US Inc. | Methods and compositions for polymerase ii (pol-ii) based guide rna expression |
| US11542466B2 (en) | 2015-12-22 | 2023-01-03 | North Carolina State University | Methods and compositions for delivery of CRISPR based antimicrobials |
| CN105543223A (zh) * | 2015-12-25 | 2016-05-04 | 华侨大学 | 一种基于miRNA/shRNA转录加工机制转录sgRNA的方法 |
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| CN106170550A (zh) | 2016-11-30 |
| WO2015153940A1 (en) | 2015-10-08 |
| US20170022499A1 (en) | 2017-01-26 |
| EP3126503A1 (en) | 2017-02-08 |
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