JP2017507142A5 - - Google Patents
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- Publication number
- JP2017507142A5 JP2017507142A5 JP2016553284A JP2016553284A JP2017507142A5 JP 2017507142 A5 JP2017507142 A5 JP 2017507142A5 JP 2016553284 A JP2016553284 A JP 2016553284A JP 2016553284 A JP2016553284 A JP 2016553284A JP 2017507142 A5 JP2017507142 A5 JP 2017507142A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- administered
- fgf
- cartilage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14000600.8 | 2014-02-20 | ||
| EP14000600 | 2014-02-20 | ||
| PCT/EP2015/053631 WO2015124731A1 (en) | 2014-02-20 | 2015-02-20 | Fgf-18 compound dosing regimen |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017507142A JP2017507142A (ja) | 2017-03-16 |
| JP2017507142A5 true JP2017507142A5 (enExample) | 2018-03-01 |
| JP6431082B2 JP6431082B2 (ja) | 2018-11-28 |
Family
ID=50151088
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016553284A Active JP6431082B2 (ja) | 2014-02-20 | 2015-02-20 | Ｆｇｆ−１８化合物の投与計画 |
| JP2016553329A Active JP6431083B2 (ja) | 2014-02-20 | 2015-02-20 | Ｆｇｆ−１８化合物の投与計画 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016553329A Active JP6431083B2 (ja) | 2014-02-20 | 2015-02-20 | Ｆｇｆ−１８化合物の投与計画 |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US9889179B2 (enExample) |
| EP (2) | EP3107559B1 (enExample) |
| JP (2) | JP6431082B2 (enExample) |
| KR (2) | KR102410986B1 (enExample) |
| CN (2) | CN106232622A (enExample) |
| AR (2) | AR099510A1 (enExample) |
| AU (2) | AU2015220777B2 (enExample) |
| BR (2) | BR112016018696A2 (enExample) |
| CA (1) | CA2938791A1 (enExample) |
| DK (2) | DK3119417T3 (enExample) |
| ES (2) | ES2688551T3 (enExample) |
| HR (2) | HRP20181572T1 (enExample) |
| HU (1) | HUE040350T2 (enExample) |
| IL (2) | IL247083B (enExample) |
| LT (2) | LT3107559T (enExample) |
| MX (2) | MX2016010872A (enExample) |
| NZ (1) | NZ723148A (enExample) |
| PL (2) | PL3119417T3 (enExample) |
| PT (2) | PT3107559T (enExample) |
| RS (2) | RS57853B1 (enExample) |
| RU (2) | RU2700582C2 (enExample) |
| SG (2) | SG11201606502YA (enExample) |
| SI (2) | SI3119417T1 (enExample) |
| WO (2) | WO2015124727A1 (enExample) |
| ZA (2) | ZA201605547B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3107559B1 (en) | 2014-02-20 | 2018-07-11 | Merck Patent GmbH | Fgf-18 compound dosing regimen |
| BR112016018681B1 (pt) | 2014-02-20 | 2021-01-05 | Merck Patent Gmbh | sistema de distribuição de substâncias que compreende pelo menos um material polimérico formador de uma matriz e um fármaco anabólico, processo de produção do mesmo e artigo de manufatura |
| WO2016120387A1 (en) | 2015-01-29 | 2016-08-04 | Ares Trading S.A. | Immunoassays for high positively charged proteins |
| DK3419625T3 (da) | 2016-02-22 | 2021-07-12 | Novartis Ag | Fremgangsmåder til anvendelse af fxr-agonister |
| PL3688468T3 (pl) | 2017-09-29 | 2022-07-18 | Merck Patent Gmbh | Biomarkery stanu zapalnego do przewidywania odpowiedzi na związek fgf-18 |
| DK3687558T3 (da) | 2017-09-29 | 2022-06-20 | Merck Patent Gmbh | Metaboliske biomarkører til forudsigelse af modtageligheden på fgf-18 forbindelse |
| IL281333B2 (en) | 2018-09-10 | 2025-11-01 | Merck Patent Gmbh | A method for reducing risk in a clinical trial |
| US20220184180A1 (en) * | 2019-02-08 | 2022-06-16 | Merck Patent Gmbh | Treatment of patients at risk of rapid progression of osteoarthritis |
| KR102920449B1 (ko) | 2023-03-29 | 2026-02-03 | 주식회사 아이프로테인테라퓨틱스 | 인터류킨-1 수용체 길항제 변이체 및 이의 용도 |
| WO2025077768A1 (en) * | 2023-10-11 | 2025-04-17 | Sichuan Real & Best Biotech Co., Ltd. | Compositions and methods for treating arthritis |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040136970A1 (en) * | 2002-10-07 | 2004-07-15 | Ellsworth Jeff L. | Methods for administering FGF18 |
| ES2706848T3 (es) * | 2004-07-06 | 2019-04-01 | Zymogenetics Inc | Composición farmacéutica que comprende FGF18 y antagonista de IL-1 y método de uso |
| US20070243132A1 (en) * | 2005-12-22 | 2007-10-18 | Apollo Life Sciences Limited | Transdermal delivery of pharmaceutical agents |
| CA2658511C (en) | 2006-08-25 | 2019-02-19 | Ares Trading S.A. | Use of fgf-18 compound to treat cartilage disorders |
| ZA200900426B (en) * | 2006-08-25 | 2010-04-28 | Ares Trading Sa | Treatment of cartilage disorders with FGF-18 |
| DE102006043260A1 (de) * | 2006-09-11 | 2008-03-27 | Krones Ag | Etikettieranlage |
| EP2688890B1 (en) * | 2011-03-22 | 2017-08-30 | Advinus Therapeutics Limited | Substituted fused tricyclic compounds, compositions and medicinal applications thereof |
| EP3107559B1 (en) | 2014-02-20 | 2018-07-11 | Merck Patent GmbH | Fgf-18 compound dosing regimen |
| AU2015220781B2 (en) | 2014-02-20 | 2018-05-24 | Merck Patent Gmbh | FGF-18 in graft transplantation and tissue engineering procedures |
| BR112016018681B1 (pt) | 2014-02-20 | 2021-01-05 | Merck Patent Gmbh | sistema de distribuição de substâncias que compreende pelo menos um material polimérico formador de uma matriz e um fármaco anabólico, processo de produção do mesmo e artigo de manufatura |
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2015
- 2015-02-20 EP EP15706006.2A patent/EP3107559B1/en active Active
- 2015-02-20 SI SI201530410T patent/SI3119417T1/sl unknown
- 2015-02-20 SG SG11201606502YA patent/SG11201606502YA/en unknown
- 2015-02-20 CN CN201580020536.2A patent/CN106232622A/zh active Pending
- 2015-02-20 AU AU2015220777A patent/AU2015220777B2/en active Active
- 2015-02-20 HR HRP20181572TT patent/HRP20181572T1/hr unknown
- 2015-02-20 PL PL15707076T patent/PL3119417T3/pl unknown
- 2015-02-20 CA CA2938791A patent/CA2938791A1/en not_active Abandoned
- 2015-02-20 LT LTEP15706006.2T patent/LT3107559T/lt unknown
- 2015-02-20 RS RS20181167A patent/RS57853B1/sr unknown
- 2015-02-20 AR ARP150100508A patent/AR099510A1/es unknown
- 2015-02-20 DK DK15707076.4T patent/DK3119417T3/en active
- 2015-02-20 ES ES15707076.4T patent/ES2688551T3/es active Active
- 2015-02-20 NZ NZ723148A patent/NZ723148A/en unknown
- 2015-02-20 AU AU2015220773A patent/AU2015220773B2/en active Active
- 2015-02-20 MX MX2016010872A patent/MX2016010872A/es active IP Right Grant
- 2015-02-20 PL PL15706006T patent/PL3107559T3/pl unknown
- 2015-02-20 WO PCT/EP2015/053624 patent/WO2015124727A1/en not_active Ceased
- 2015-02-20 SI SI201530428T patent/SI3107559T1/sl unknown
- 2015-02-20 US US15/120,131 patent/US9889179B2/en active Active
- 2015-02-20 CN CN201580020532.4A patent/CN106456713A/zh active Pending
- 2015-02-20 KR KR1020167025246A patent/KR102410986B1/ko active Active
- 2015-02-20 RU RU2016137292A patent/RU2700582C2/ru active
- 2015-02-20 DK DK15706006.2T patent/DK3107559T3/en active
- 2015-02-20 WO PCT/EP2015/053631 patent/WO2015124731A1/en not_active Ceased
- 2015-02-20 HR HRP20181570TT patent/HRP20181570T1/hr unknown
- 2015-02-20 SG SG11201606505UA patent/SG11201606505UA/en unknown
- 2015-02-20 PT PT15706006T patent/PT3107559T/pt unknown
- 2015-02-20 JP JP2016553284A patent/JP6431082B2/ja active Active
- 2015-02-20 RS RS20181168A patent/RS57709B1/sr unknown
- 2015-02-20 KR KR1020167025245A patent/KR102410988B1/ko active Active
- 2015-02-20 HU HUE15706006A patent/HUE040350T2/hu unknown
- 2015-02-20 RU RU2016137289A patent/RU2691946C2/ru active
- 2015-02-20 US US15/120,134 patent/US9724388B2/en active Active
- 2015-02-20 LT LTEP15707076.4T patent/LT3119417T/lt unknown
- 2015-02-20 ES ES15706006.2T patent/ES2689071T3/es active Active
- 2015-02-20 JP JP2016553329A patent/JP6431083B2/ja active Active
- 2015-02-20 BR BR112016018696A patent/BR112016018696A2/pt not_active Application Discontinuation
- 2015-02-20 AR ARP150100507A patent/AR099558A1/es unknown
- 2015-02-20 EP EP15707076.4A patent/EP3119417B1/en active Active
- 2015-02-20 BR BR112016018685A patent/BR112016018685A2/pt not_active Application Discontinuation
- 2015-02-20 MX MX2016010871A patent/MX2016010871A/es active IP Right Grant
- 2015-02-20 PT PT15707076T patent/PT3119417T/pt unknown
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2016
- 2016-08-03 IL IL247083A patent/IL247083B/en active IP Right Grant
- 2016-08-03 IL IL247084A patent/IL247084B/en active IP Right Grant
- 2016-08-10 ZA ZA2016/05547A patent/ZA201605547B/en unknown
- 2016-08-10 ZA ZA2016/05548A patent/ZA201605548B/en unknown