JP2017507145A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017507145A5 JP2017507145A5 JP2016553402A JP2016553402A JP2017507145A5 JP 2017507145 A5 JP2017507145 A5 JP 2017507145A5 JP 2016553402 A JP2016553402 A JP 2016553402A JP 2016553402 A JP2016553402 A JP 2016553402A JP 2017507145 A5 JP2017507145 A5 JP 2017507145A5
- Authority
- JP
- Japan
- Prior art keywords
- delivery system
- substance delivery
- matrix
- polymeric material
- anabolic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14000598.4 | 2014-02-20 | ||
| EP14000598 | 2014-02-20 | ||
| PCT/EP2015/053645 WO2015124739A1 (en) | 2014-02-20 | 2015-02-20 | Implant comprising fgf-18 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017507145A JP2017507145A (ja) | 2017-03-16 |
| JP2017507145A5 true JP2017507145A5 (enExample) | 2018-02-22 |
| JP6510547B2 JP6510547B2 (ja) | 2019-05-08 |
Family
ID=50151086
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016553402A Active JP6510547B2 (ja) | 2014-02-20 | 2015-02-20 | Ｆｇｆ−１８を含むインプラント |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US10086112B2 (enExample) |
| EP (1) | EP3107592B1 (enExample) |
| JP (1) | JP6510547B2 (enExample) |
| KR (1) | KR102421950B1 (enExample) |
| CN (1) | CN106232154A (enExample) |
| AR (1) | AR099556A1 (enExample) |
| AU (1) | AU2015220785B2 (enExample) |
| BR (1) | BR112016018681B1 (enExample) |
| CA (1) | CA2938796C (enExample) |
| DK (1) | DK3107592T3 (enExample) |
| ES (1) | ES2698117T3 (enExample) |
| HR (1) | HRP20181573T1 (enExample) |
| IL (1) | IL247106B (enExample) |
| LT (1) | LT3107592T (enExample) |
| MX (1) | MX368946B (enExample) |
| NZ (1) | NZ723177A (enExample) |
| PL (1) | PL3107592T3 (enExample) |
| PT (1) | PT3107592T (enExample) |
| RS (1) | RS58138B1 (enExample) |
| RU (1) | RU2700414C2 (enExample) |
| SG (1) | SG11201606697YA (enExample) |
| SI (1) | SI3107592T1 (enExample) |
| WO (1) | WO2015124739A1 (enExample) |
| ZA (1) | ZA201605667B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2959509T1 (sl) | 2013-02-14 | 2018-11-30 | Nanopareil, Llc | Polst iz elektropredenih hibridnih nanovlaken, postopek za izdelavo le-te in postopek čiščenja biomolekul |
| HRP20181570T1 (hr) | 2014-02-20 | 2018-11-30 | Merck Patent Gmbh | Režim doziranja spoja fgf-18 |
| CA2971315C (en) | 2015-01-29 | 2023-02-14 | Ares Trading S.A. | Immunoassays for high positively charged proteins |
| LT3687558T (lt) | 2017-09-29 | 2022-06-27 | Merck Patent Gmbh | Metaboliniai biožymenys, skirti atsako į fgf-18 junginį numatymui |
| RS63292B1 (sr) | 2017-09-29 | 2022-06-30 | Merck Patent Gmbh | Inflamatorni biomarkeri za predviđanje responsivnosti na jedinjenje fgf-18 |
| IL281333B2 (en) | 2018-09-10 | 2025-11-01 | Merck Patent Gmbh | A method for reducing risk in a clinical trial |
| CN117187255B (zh) * | 2023-11-07 | 2024-01-30 | 北京大学第三医院（北京大学第三临床医学院） | 编码FGF18或rhFGF18的mRNA及其在骨关节炎治疗中的应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6511958B1 (en) * | 1997-08-14 | 2003-01-28 | Sulzer Biologics, Inc. | Compositions for regeneration and repair of cartilage lesions |
| DE69714035T2 (de) * | 1997-08-14 | 2003-03-06 | Sulzer Innotec Ag, Winterthur | Zusammensetzung und Vorrichtung zur Reparatur von Knorpelgewebe in vivo bestehend aus Nanokapseln mit osteoinduktiven und/oder chondroinduktiven Faktoren |
| KR100380119B1 (ko) * | 2001-04-19 | 2003-04-11 | 한국항공우주연구원 | 이원화된 통신속도 적응형 베이스 밴드 스위칭 위상시프트 키잉 장치 |
| EP1273365A1 (fr) * | 2001-07-06 | 2003-01-08 | Recherche Et Developpement Du Groupe Cockerill Sambre | Outils rotatifs pour le perçage en ligne de produits profiles |
| EP1551426B1 (en) * | 2002-10-07 | 2014-06-25 | ZymoGenetics, Inc. | Methods of administering fgf18 |
| US8852240B2 (en) * | 2004-10-25 | 2014-10-07 | Kieran Murphy, Llc | Methods and compositions for fostering and preserving bone growth |
| DK1828239T3 (da) * | 2004-12-10 | 2011-12-19 | Zymogenetics Inc | FGF18-produktion i prokaryote værter |
| NZ574216A (en) * | 2006-08-25 | 2011-11-25 | Ares Trading Sa | Treatment of cartilage disorders with fgf-18 |
| JP2012519556A (ja) | 2009-03-05 | 2012-08-30 | バイオミメティック セラピューティクス， インコーポレイテッド | 骨軟骨欠損を治療するための血小板由来増殖因子組成物および方法 |
| US8431399B2 (en) | 2010-03-02 | 2013-04-30 | Taipei Medical University | Method to restore cartilaginous phenotype of chondrocytes after cultured and expanded in vitro |
| WO2012094511A2 (en) * | 2011-01-05 | 2012-07-12 | Rhode Island Hospital | Compositions and methods for the treatment of orthopedic disease or injury |
| JP5990720B2 (ja) * | 2011-02-22 | 2016-09-14 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 骨再生及び／又は軟骨再生に使用するためのナノリザーバー技術 |
| KR102434024B1 (ko) * | 2013-12-24 | 2022-08-22 | 아레스 트레이딩 에스.아. | 알지네이트/콜라겐 히드로겔 중의 fgf-18 제형물 |
| HRP20181570T1 (hr) | 2014-02-20 | 2018-11-30 | Merck Patent Gmbh | Režim doziranja spoja fgf-18 |
| KR102437057B1 (ko) | 2014-02-20 | 2022-08-26 | 메르크 파텐트 게엠베하 | 이식편 이식 및 조직 공학 절차에 있어서의 ｆｇｆ－１８ |
-
2015
- 2015-02-20 ES ES15706011T patent/ES2698117T3/es active Active
- 2015-02-20 HR HRP20181573TT patent/HRP20181573T1/hr unknown
- 2015-02-20 WO PCT/EP2015/053645 patent/WO2015124739A1/en not_active Ceased
- 2015-02-20 BR BR112016018681-8A patent/BR112016018681B1/pt active IP Right Grant
- 2015-02-20 KR KR1020167025247A patent/KR102421950B1/ko active Active
- 2015-02-20 SG SG11201606697YA patent/SG11201606697YA/en unknown
- 2015-02-20 US US15/120,137 patent/US10086112B2/en active Active
- 2015-02-20 SI SI201530409T patent/SI3107592T1/sl unknown
- 2015-02-20 AU AU2015220785A patent/AU2015220785B2/en active Active
- 2015-02-20 CN CN201580020527.3A patent/CN106232154A/zh active Pending
- 2015-02-20 NZ NZ723177A patent/NZ723177A/en unknown
- 2015-02-20 EP EP15706011.2A patent/EP3107592B1/en active Active
- 2015-02-20 CA CA2938796A patent/CA2938796C/en active Active
- 2015-02-20 LT LTEP15706011.2T patent/LT3107592T/lt unknown
- 2015-02-20 AR ARP150100505A patent/AR099556A1/es not_active Application Discontinuation
- 2015-02-20 PL PL15706011T patent/PL3107592T3/pl unknown
- 2015-02-20 RU RU2016137291A patent/RU2700414C2/ru active
- 2015-02-20 PT PT15706011T patent/PT3107592T/pt unknown
- 2015-02-20 MX MX2016010874A patent/MX368946B/es active IP Right Grant
- 2015-02-20 DK DK15706011.2T patent/DK3107592T3/en active
- 2015-02-20 JP JP2016553402A patent/JP6510547B2/ja active Active
- 2015-02-20 RS RS20181404A patent/RS58138B1/sr unknown
-
2016
- 2016-08-04 IL IL247106A patent/IL247106B/en active IP Right Grant
- 2016-08-16 ZA ZA2016/05667A patent/ZA201605667B/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Haggerty et al. | Biomaterials for revascularization and immunomodulation after spinal cord injury | |
| RU2016137291A (ru) | Имплантат, содержащий fgf-18 | |
| PH12018500162A1 (en) | 1,3,4-oxadiazole amide derivative compound as histone deacetylase 6 inhibitor, and pharmaceutical composition containing same | |
| JP2014139220A5 (enExample) | ||
| MX384527B (es) | Compuestos derivados de oxadiazolamina como inhibidores de histona desacetilasa 6, y la composición farmacéutica que comprende los mismos | |
| JP2017512194A5 (enExample) | ||
| JP2014221830A5 (enExample) | ||
| MY194018A (en) | 1,3,4-oxadiazole sulfamide derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same | |
| JP2017507142A5 (enExample) | ||
| JP2016517888A5 (enExample) | ||
| RU2016137292A (ru) | Схема применения соединения fgf-18 | |
| JP2017501140A5 (enExample) | ||
| WO2021034958A3 (en) | Materials for delivery of tetherable proteins in bone implants | |
| JP2017522288A5 (enExample) | ||
| JP2011528333A5 (enExample) | ||
| JP2018521643A5 (enExample) | ||
| JP2017519568A5 (enExample) | ||
| KR20120014251A (ko) | 동종이식편의 접합을 개선하기 위한 생체활성 코팅 조성물 및 방법 | |
| HRP20180061T1 (hr) | Indolkarbonitrili kao selektivni modulatori androgenskih receptora | |
| NZ729628A (en) | Methods for the treatment of peri-implantitis | |
| JP2013520271A5 (enExample) | ||
| Zhu et al. | Photothermal-driven multifunctional injectable hydrogel platform for promoting diabetic bone defect repair through synergistic immunomodulation and bone homeostasis | |
| Zeng et al. | Decellularized small intestinal hydrogel-encapsulated BMSCs attenuate dextran sulfate sodium-induced colitis in mice via immunomodulation and tissue repair | |
| EP4470625A3 (en) | A pharmaceutical composition comprising a combination of probiotic and prebiotic to treat stunting | |
| ME02644B (me) | Novi preparati alfentanila za tretman akutnog bola |