SG11201606697YA - Implant comprising fgf-18 - Google Patents

Implant comprising fgf-18

Info

Publication number
SG11201606697YA
SG11201606697YA SG11201606697YA SG11201606697YA SG11201606697YA SG 11201606697Y A SG11201606697Y A SG 11201606697YA SG 11201606697Y A SG11201606697Y A SG 11201606697YA SG 11201606697Y A SG11201606697Y A SG 11201606697YA SG 11201606697Y A SG11201606697Y A SG 11201606697YA
Authority
SG
Singapore
Prior art keywords
fgf
implant
Prior art date
Application number
SG11201606697YA
Inventor
Christoph H Ladel
Hans Guehring
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of SG11201606697YA publication Critical patent/SG11201606697YA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1825Fibroblast growth factor [FGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/26Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3817Cartilage-forming cells, e.g. pre-chondrocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/50Fibroblast growth factors [FGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents
    • A61L2300/414Growth factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/06Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
SG11201606697YA 2014-02-20 2015-02-20 Implant comprising fgf-18 SG11201606697YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14000598 2014-02-20
PCT/EP2015/053645 WO2015124739A1 (en) 2014-02-20 2015-02-20 Implant comprising fgf-18

Publications (1)

Publication Number Publication Date
SG11201606697YA true SG11201606697YA (en) 2016-09-29

Family

ID=50151086

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201606697YA SG11201606697YA (en) 2014-02-20 2015-02-20 Implant comprising fgf-18

Country Status (24)

Country Link
US (1) US10086112B2 (en)
EP (1) EP3107592B1 (en)
JP (1) JP6510547B2 (en)
KR (1) KR102421950B1 (en)
CN (1) CN106232154A (en)
AR (1) AR099556A1 (en)
AU (1) AU2015220785B2 (en)
BR (1) BR112016018681B1 (en)
CA (1) CA2938796C (en)
DK (1) DK3107592T3 (en)
ES (1) ES2698117T3 (en)
HR (1) HRP20181573T1 (en)
IL (1) IL247106B (en)
LT (1) LT3107592T (en)
MX (1) MX368946B (en)
NZ (1) NZ723177A (en)
PL (1) PL3107592T3 (en)
PT (1) PT3107592T (en)
RS (1) RS58138B1 (en)
RU (1) RU2700414C2 (en)
SG (1) SG11201606697YA (en)
SI (1) SI3107592T1 (en)
WO (1) WO2015124739A1 (en)
ZA (1) ZA201605667B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2911888C (en) 2013-02-14 2017-09-19 Nanopareil, Llc Hybrid felts of electrospun nanofibers
PT3107559T (en) 2014-02-20 2018-10-31 Merck Patent Gmbh Fgf-18 compound dosing regimen
CN117187255B (en) * 2023-11-07 2024-01-30 北京大学第三医院(北京大学第三临床医学院) mRNAs encoding FGF18 or rhFGF18 and use thereof in the treatment of osteoarthritis

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69714035T2 (en) * 1997-08-14 2003-03-06 Sulzer Innotec Ag Composition and device for repairing cartilage tissue in vivo consisting of nanocapsules with osteoinductive and / or chondroinductive factors
US6511958B1 (en) 1997-08-14 2003-01-28 Sulzer Biologics, Inc. Compositions for regeneration and repair of cartilage lesions
KR100380119B1 (en) * 2001-04-19 2003-04-11 한국항공우주연구원 PSK Baseband Signal switching unit for two-type data rate
EP1273365A1 (en) * 2001-07-06 2003-01-08 Recherche Et Developpement Du Groupe Cockerill Sambre Rotary cutting tool for continuous perforating of profiles
AU2003279835B2 (en) 2002-10-07 2009-09-10 Zymogenetics, Inc. Methods of administering FGF18
US8852240B2 (en) 2004-10-25 2014-10-07 Kieran Murphy, Llc Methods and compositions for fostering and preserving bone growth
AU2005314438B2 (en) * 2004-12-10 2012-03-29 Zymogenetics, Inc. FGF18 production in prokaryotic hosts
BRPI0715728A8 (en) * 2006-08-25 2018-04-03 Ares Trading Sa treatment of cartilage disorders
CA2754501A1 (en) 2009-03-05 2010-09-10 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods for the treatment of osteochondral defects
US8431399B2 (en) 2010-03-02 2013-04-30 Taipei Medical University Method to restore cartilaginous phenotype of chondrocytes after cultured and expanded in vitro
US10130687B2 (en) * 2011-01-05 2018-11-20 Rhode Island Hospital Compositions and methods for the treatment of orthopedic disease or injury
EP2678048B1 (en) * 2011-02-22 2018-11-21 Institut National de la Sante et de la Recherche Medicale (INSERM) Nano-reservoirs technology for use in bone and/or cartilage regeneration
JP6487448B2 (en) * 2013-12-24 2019-03-20 アレス トレーディング ソシエテ アノニム FGF-18 formulation in alginate / collagen hydrogel
RU2682159C2 (en) 2014-02-20 2019-03-15 Мерк Патент Гмбх Fgf-18 in transplantation and tissue engineering procedures
PT3107559T (en) 2014-02-20 2018-10-31 Merck Patent Gmbh Fgf-18 compound dosing regimen

Also Published As

Publication number Publication date
JP2017507145A (en) 2017-03-16
JP6510547B2 (en) 2019-05-08
RU2700414C2 (en) 2019-09-17
PT3107592T (en) 2018-12-03
RU2016137291A (en) 2018-03-21
AU2015220785B2 (en) 2018-07-19
PL3107592T3 (en) 2019-02-28
AU2015220785A1 (en) 2016-09-01
CA2938796A1 (en) 2015-08-27
US10086112B2 (en) 2018-10-02
SI3107592T1 (en) 2018-11-30
ES2698117T3 (en) 2019-01-31
KR102421950B1 (en) 2022-07-18
BR112016018681B1 (en) 2021-01-05
LT3107592T (en) 2018-12-10
RS58138B1 (en) 2019-02-28
MX2016010874A (en) 2016-11-17
CA2938796C (en) 2022-08-02
RU2016137291A3 (en) 2018-08-28
MX368946B (en) 2019-10-22
IL247106B (en) 2020-02-27
BR112016018681A2 (en) 2017-10-17
IL247106A0 (en) 2016-09-29
EP3107592B1 (en) 2018-08-22
AR099556A1 (en) 2016-08-03
ZA201605667B (en) 2018-12-19
WO2015124739A1 (en) 2015-08-27
DK3107592T3 (en) 2018-11-12
HRP20181573T1 (en) 2018-11-30
KR20160124806A (en) 2016-10-28
US20170056560A1 (en) 2017-03-02
EP3107592A1 (en) 2016-12-28
NZ723177A (en) 2021-12-24
CN106232154A (en) 2016-12-14

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