JP2017505621A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017505621A5 JP2017505621A5 JP2016549152A JP2016549152A JP2017505621A5 JP 2017505621 A5 JP2017505621 A5 JP 2017505621A5 JP 2016549152 A JP2016549152 A JP 2016549152A JP 2016549152 A JP2016549152 A JP 2016549152A JP 2017505621 A5 JP2017505621 A5 JP 2017505621A5
- Authority
- JP
- Japan
- Prior art keywords
- tcr
- bait
- polypeptide chain
- nucleic acid
- chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461933048P | 2014-01-29 | 2014-01-29 | |
| US61/933,048 | 2014-01-29 | ||
| PCT/CA2015/000049 WO2015113140A1 (en) | 2014-01-29 | 2015-01-28 | Methods and compositions for producing a cell expressing a t cell receptor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017505621A JP2017505621A (ja) | 2017-02-23 |
| JP2017505621A5 true JP2017505621A5 (https=) | 2018-03-08 |
| JP6580579B2 JP6580579B2 (ja) | 2019-09-25 |
Family
ID=53756056
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016549152A Active JP6580579B2 (ja) | 2014-01-29 | 2015-01-28 | Ｔ細胞受容体を発現する細胞を生産する方法および組成物 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10654907B2 (https=) |
| EP (1) | EP3099708B1 (https=) |
| JP (1) | JP6580579B2 (https=) |
| CA (1) | CA2934729C (https=) |
| WO (1) | WO2015113140A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2998270A1 (en) | 2015-10-01 | 2017-04-06 | Ospedale San Raffaele S.R.L. | Tcr and uses thereof |
| RU2729116C2 (ru) | 2015-12-16 | 2020-08-04 | Гритстоун Онколоджи, Инк. | Идентификация, производство и применение неоантигенов |
| US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
| MA45491A (fr) * | 2016-06-27 | 2019-05-01 | Juno Therapeutics Inc | Épitopes à restriction cmh-e, molécules de liaison et procédés et utilisations associés |
| CN109804246B (zh) * | 2016-08-01 | 2022-05-17 | 健康研究公司 | 用于快速克隆t细胞受体的组合物和方法 |
| US10822662B2 (en) * | 2017-03-06 | 2020-11-03 | Karkinos Precision Oncology LLC | Diagnostic methods for identifying T-cell lymphoma and leukemia by high-throughput TCR-β sequencing |
| KR20260039788A (ko) | 2017-10-10 | 2026-03-20 | 시애틀 프로젝트 코포레이션 | 핫스팟을 이용한 신생항원 동정 |
| CA3083097A1 (en) | 2017-11-22 | 2019-05-31 | Gritstone Oncology, Inc. | Reducing junction epitope presentation for neoantigens |
| CN113226475B (zh) * | 2018-12-26 | 2026-03-17 | 麒麟控股株式会社 | 改造tcr及其制造方法 |
| JP6821230B2 (ja) | 2019-02-04 | 2021-01-27 | 国立大学法人愛媛大学 | ＣＡＲライブラリおよびｓｃＦｖの製造方法 |
| GB202211194D0 (en) * | 2022-08-01 | 2022-09-14 | Univ College Cardiff Consultants Ltd | Novel TCRs |
| WO2026019786A1 (en) * | 2024-07-16 | 2026-01-22 | Board Of Regents, The University Of Texas System | Peptides and engineered t cell receptors targeting brachyury antigen and methods of use |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1795599A1 (en) * | 2005-12-09 | 2007-06-13 | Schuler, Gerold, Prof. Dr. | Methods for generating antigen-specific effector T cells |
| WO2008042814A2 (en) | 2006-09-29 | 2008-04-10 | California Institute Of Technology | Mart-1 t cell receptors |
| US9051391B2 (en) * | 2007-06-11 | 2015-06-09 | Takara Bio Inc. | Method for expression of specific gene |
| CN102272153B (zh) * | 2008-11-24 | 2015-04-15 | 德国慕尼黑亥姆霍兹研究中心健康和环境有限公司 | 高亲和力t细胞受体及其应用 |
| WO2010089412A1 (en) * | 2009-02-09 | 2010-08-12 | Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Fuer Gesundheit Und Umwelt (Gmbh) | Repertoire of allo-restricted peptide-specific t cell receptor sequences and use thereof |
| CN103124740B (zh) * | 2010-09-21 | 2015-09-02 | 美国卫生和人力服务部 | 抗-ssx-2t细胞受体和相关材料及使用方法 |
| EP2670848B1 (en) * | 2011-02-06 | 2016-02-03 | Yeda Research and Development Co. Ltd | Affinity maturated t cell receptors and use thereof |
| US9746470B2 (en) * | 2011-05-09 | 2017-08-29 | Whitehead Institute For Biomedical Research | Chaperone interaction assays and uses thereof |
| JP6378172B2 (ja) * | 2012-05-22 | 2018-08-22 | アメリカ合衆国 | マウス抗ｎｙ−ｅｓｏ−１ｔ細胞受容体 |
-
2015
- 2015-01-28 JP JP2016549152A patent/JP6580579B2/ja active Active
- 2015-01-28 US US15/111,639 patent/US10654907B2/en active Active
- 2015-01-28 EP EP15744002.5A patent/EP3099708B1/en active Active
- 2015-01-28 WO PCT/CA2015/000049 patent/WO2015113140A1/en not_active Ceased
- 2015-01-28 CA CA2934729A patent/CA2934729C/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017505621A5 (https=) | ||
| JP7439002B2 (ja) | ヒト化抗ｃｄ１９キメラ抗原受容体を使用するがんの処置 | |
| TWI710572B (zh) | 改善配對的ｔ細胞受體 | |
| KR102742220B1 (ko) | 항-hla-a2 항체 및 그 사용 방법 | |
| ES2963718T3 (es) | Capacidad presentadora de antígenos de células CAR-T potenciada mediante introducción conjunta de moléculas co-estimuladoras | |
| JP2021118723A (ja) | 免疫療法のためのマクロファージの遺伝子組換え | |
| JP2018183175A (ja) | Ｗｔ−１に特異的なｔ細胞免疫治療 | |
| KR20240028975A (ko) | Cd8-특이적 항체 구조체들 및 이의 조성물 | |
| JP2020536527A (ja) | Ｂｃｍａに結合するキメラ抗原受容体（ｃａｒ）及びその応用 | |
| KR20230152035A (ko) | 표적 단백질 분해 시스템 및 이의 응용 | |
| TW201922774A (zh) | 標靶bcma嵌合抗原受體、標靶cd19嵌合抗原受體及組合療法 | |
| TW201930591A (zh) | 用於與嵌合抗原受體療法併用之免疫增強rna | |
| JP7447014B2 (ja) | インターロイキン２３受容体に特異的なキメラ抗原受容体 | |
| WO2018026819A2 (en) | Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-m2 macrophage molecule | |
| KR20190016966A (ko) | 길항성 항-종양 괴사 인자 수용체 슈퍼패밀리 항체 | |
| CN107708710A (zh) | Smart CAR装置,DE CAR多肽,Side CAR及其使用 | |
| TW201446794A (zh) | 利用抗－ｃｄ１２３嵌合抗原受體工程化ｔ細胞之初級人類白血病有效靶向 | |
| US20230044451A1 (en) | Methods and compositions for the delivery of modified lymphocytes and/or retroviral particles | |
| CA3090249A1 (en) | Combination therapy using a chimeric antigen receptor | |
| JP2023500318A (ja) | 細胞選択および／または細胞刺激デバイスならびに使用方法 | |
| CN120917046A (zh) | 新型cd19结合剂、包含所述cd19结合剂的car-t构建体及其使用方法 | |
| WO2021074313A1 (en) | Chimeric antigen receptor specific for interleukin-23 receptor | |
| WO2023010068A2 (en) | Multiprotein-engineered cells secreting a multispecific antibody | |
| CN117279945A (zh) | 嵌合细胞因子受体及其在细胞疗法中的用途 | |
| US20210340524A1 (en) | Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof |