JP2017505621A5 - - Google Patents

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Publication number
JP2017505621A5
JP2017505621A5 JP2016549152A JP2016549152A JP2017505621A5 JP 2017505621 A5 JP2017505621 A5 JP 2017505621A5 JP 2016549152 A JP2016549152 A JP 2016549152A JP 2016549152 A JP2016549152 A JP 2016549152A JP 2017505621 A5 JP2017505621 A5 JP 2017505621A5
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JP
Japan
Prior art keywords
tcr
bait
polypeptide chain
nucleic acid
chain
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JP2016549152A
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English (en)
Japanese (ja)
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JP6580579B2 (ja
JP2017505621A (ja
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Priority claimed from PCT/CA2015/000049 external-priority patent/WO2015113140A1/en
Publication of JP2017505621A publication Critical patent/JP2017505621A/ja
Publication of JP2017505621A5 publication Critical patent/JP2017505621A5/ja
Application granted granted Critical
Publication of JP6580579B2 publication Critical patent/JP6580579B2/ja
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JP2016549152A 2014-01-29 2015-01-28 Ｔ細胞受容体を発現する細胞を生産する方法および組成物 Active JP6580579B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461933048P 2014-01-29 2014-01-29
US61/933,048 2014-01-29
PCT/CA2015/000049 WO2015113140A1 (en) 2014-01-29 2015-01-28 Methods and compositions for producing a cell expressing a t cell receptor

Publications (3)

Publication Number Publication Date
JP2017505621A JP2017505621A (ja) 2017-02-23
JP2017505621A5 true JP2017505621A5 (https=) 2018-03-08
JP6580579B2 JP6580579B2 (ja) 2019-09-25

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ID=53756056

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016549152A Active JP6580579B2 (ja) 2014-01-29 2015-01-28 Ｔ細胞受容体を発現する細胞を生産する方法および組成物

Country Status (5)

Country Link
US (1) US10654907B2 (https=)
EP (1) EP3099708B1 (https=)
JP (1) JP6580579B2 (https=)
CA (1) CA2934729C (https=)
WO (1) WO2015113140A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2998270A1 (en) * 2015-10-01 2017-04-06 Ospedale San Raffaele S.R.L. Tcr and uses thereof
ES2970865T3 (es) 2015-12-16 2024-05-31 Gritstone Bio Inc Identificación, fabricación y uso de neoantígenos
US11214789B2 (en) 2016-05-03 2022-01-04 Flodesign Sonics, Inc. Concentration and washing of particles with acoustics
EP3475706B1 (en) * 2016-06-27 2021-08-11 Juno Therapeutics, Inc. Mhc-e restricted epitopes, binding molecules and related methods and uses
ES2877820T3 (es) * 2016-08-01 2021-11-17 Health Research Inc Composiciones y métodos para la clonación rápida de receptores de células T
US10822662B2 (en) * 2017-03-06 2020-11-03 Karkinos Precision Oncology LLC Diagnostic methods for identifying T-cell lymphoma and leukemia by high-throughput TCR-β sequencing
EP4576103A3 (en) 2017-10-10 2025-08-27 Gritstone bio, Inc. Neoantigen identification using hotspots
CN111630602A (zh) 2017-11-22 2020-09-04 磨石肿瘤生物技术公司 减少新抗原的接合表位呈递
WO2020138371A1 (ja) * 2018-12-26 2020-07-02 キリンホールディングス株式会社 改変ｔｃｒ及びその製造方法
US12241061B2 (en) 2019-02-04 2025-03-04 National University Corporation Ehime University CAR library and scFv manufacturing method
GB202211194D0 (en) * 2022-08-01 2022-09-14 Univ College Cardiff Consultants Ltd Novel TCRs
WO2026019786A1 (en) * 2024-07-16 2026-01-22 Board Of Regents, The University Of Texas System Peptides and engineered t cell receptors targeting brachyury antigen and methods of use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1795599A1 (en) 2005-12-09 2007-06-13 Schuler, Gerold, Prof. Dr. Methods for generating antigen-specific effector T cells
US8119772B2 (en) * 2006-09-29 2012-02-21 California Institute Of Technology MART-1 T cell receptors
KR101363928B1 (ko) * 2007-06-11 2014-02-19 고쿠리츠다이가쿠호진 미에다이가쿠 특이적 유전자 발현 방법
DK2352756T3 (da) * 2008-11-24 2012-12-03 Helmholtz Zentrum Muenchen Højaffin T-cellereceptor og anvendelse af denne
WO2010089412A1 (en) * 2009-02-09 2010-08-12 Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Fuer Gesundheit Und Umwelt (Gmbh) Repertoire of allo-restricted peptide-specific t cell receptor sequences and use thereof
CN103124740B (zh) * 2010-09-21 2015-09-02 美国卫生和人力服务部 抗-ssx-2t细胞受体和相关材料及使用方法
EP2670848B1 (en) * 2011-02-06 2016-02-03 Yeda Research and Development Co. Ltd Affinity maturated t cell receptors and use thereof
WO2012154858A1 (en) * 2011-05-09 2012-11-15 Whitehead Institute For Biomedical Research Chaperone interaction assays and uses thereof
EP2852613B1 (en) * 2012-05-22 2019-01-23 The United States of America, as represented by The Secretary, Department of Health and Human Services Murine anti-ny-eso-1 t cell receptors

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