JP2017501689A5 - - Google Patents
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- Publication number
- JP2017501689A5 JP2017501689A5 JP2016534708A JP2016534708A JP2017501689A5 JP 2017501689 A5 JP2017501689 A5 JP 2017501689A5 JP 2016534708 A JP2016534708 A JP 2016534708A JP 2016534708 A JP2016534708 A JP 2016534708A JP 2017501689 A5 JP2017501689 A5 JP 2017501689A5
- Authority
- JP
- Japan
- Prior art keywords
- mirna
- surfactant
- binding protein
- biological fluid
- protein reagent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002679 microRNA Substances 0.000 claims 19
- 238000000034 method Methods 0.000 claims 14
- 108700011259 MicroRNAs Proteins 0.000 claims 10
- 239000013060 biological fluid Substances 0.000 claims 9
- 102000023732 binding proteins Human genes 0.000 claims 8
- 108091008324 binding proteins Proteins 0.000 claims 8
- 239000003153 chemical reaction reagent Substances 0.000 claims 8
- 239000004094 surface-active agent Substances 0.000 claims 8
- 108091005804 Peptidases Proteins 0.000 claims 4
- 239000004365 Protease Substances 0.000 claims 4
- 239000007787 solid Substances 0.000 claims 4
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 3
- 108010067770 Endopeptidase K Proteins 0.000 claims 2
- 239000011324 bead Substances 0.000 claims 2
- 238000001114 immunoprecipitation Methods 0.000 claims 2
- 239000002736 nonionic surfactant Substances 0.000 claims 2
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 1
- 102000035195 Peptidases Human genes 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 108091070501 miRNA Proteins 0.000 claims 1
- 102000026934 miRNA binding proteins Human genes 0.000 claims 1
- 108091008480 miRNA binding proteins Proteins 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361909834P | 2013-11-27 | 2013-11-27 | |
| US61/909,834 | 2013-11-27 | ||
| US201461985000P | 2014-04-28 | 2014-04-28 | |
| US61/985,000 | 2014-04-28 | ||
| PCT/US2014/067321 WO2015094609A1 (en) | 2013-11-27 | 2014-11-25 | Micro rna isolation from biological fluid |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017501689A JP2017501689A (ja) | 2017-01-19 |
| JP2017501689A5 true JP2017501689A5 (enExample) | 2018-01-11 |
| JP6644686B2 JP6644686B2 (ja) | 2020-02-12 |
Family
ID=53403495
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016534708A Active JP6644686B2 (ja) | 2013-11-27 | 2014-11-25 | 生物学的流体からのマイクロｒｎａ単離 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10131902B2 (enExample) |
| EP (2) | EP3702361B1 (enExample) |
| JP (1) | JP6644686B2 (enExample) |
| KR (1) | KR102181103B1 (enExample) |
| CN (2) | CN110511924B (enExample) |
| BR (1) | BR112016011770B1 (enExample) |
| CA (1) | CA2930704C (enExample) |
| ES (2) | ES2778223T3 (enExample) |
| IL (1) | IL245646B (enExample) |
| WO (1) | WO2015094609A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10131902B2 (en) | 2013-11-27 | 2018-11-20 | Sigma-Aldrich Co. Llc | Micro RNA isolation from biological fluid |
| CN107385014B (zh) * | 2017-06-13 | 2020-12-22 | 深圳大学 | 一种直接定量检测循环miRNA的RT-qPCR方法 |
| KR102003594B1 (ko) | 2017-08-08 | 2019-07-24 | 숙명여자대학교산학협력단 | 염증 반응 매개 신혈관생성 질환 진단용 조성물 |
| US11674133B2 (en) | 2017-09-13 | 2023-06-13 | Becton, Dickinson And Company | Methods and compositions for extracting nucleic acids using ferric oxide particles |
| EP3768850B1 (en) | 2018-03-22 | 2025-07-30 | IDEXX Laboratories, Inc. | Methods for measuring bacteria in biological samples |
| CN109490533B (zh) * | 2018-12-29 | 2022-02-15 | 南京澳林生物科技有限公司 | 一种胃蛋白酶原ⅱ(pgⅱ)检测试剂盒及生产工艺 |
| WO2022093701A1 (en) * | 2020-10-26 | 2022-05-05 | Eclipse Bioinnovations, Inc. | Methods and kits for enriching for polynucleotides |
| WO2023023584A2 (en) | 2021-08-19 | 2023-02-23 | Eclipse Bioinnovations, Inc. | Methods for detecting rna binding protein complexes |
| CN113980954A (zh) * | 2021-11-11 | 2022-01-28 | 德州学院 | 一种病毒rna保护剂及其制备方法与应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20070007253A (ko) * | 2003-10-08 | 2007-01-15 | 이바이오사이언스 | 천연 면역글로불린 결합 물질 및 이의 제조 방법 및 사용방법 |
| JP5349838B2 (ja) * | 2007-11-30 | 2013-11-20 | 和光純薬工業株式会社 | ｓｍａｌｌＲＮＡの取得用担体、取得方法及び取得用試薬 |
| WO2010014636A1 (en) * | 2008-07-28 | 2010-02-04 | Rockefeller University | Methods for identifying rna segments bound by rna-binding proteins or ribonucleoprotein complexes |
| US8846314B2 (en) * | 2009-03-03 | 2014-09-30 | The Board Of Trustees Of The Leland Stanford Junior University | Isotachophoretic focusing of nucleic acids |
| JP5867402B2 (ja) * | 2010-09-24 | 2016-02-24 | 和光純薬工業株式会社 | ｓｍａｌｌＲＮＡの取得方法 |
| WO2012115885A1 (en) * | 2011-02-22 | 2012-08-30 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Circulating biomarkers |
| JP6309450B2 (ja) * | 2011-08-04 | 2018-04-11 | イェダ リサーチ アンド デベロップメント カンパニー リミテッド | セロトニン関連の医学的状態、アドレナリン関連の医学的状態、ノルアドレナリン関連の医学的状態、グルタミン酸関連の医学的状態および副腎皮質刺激ホルモン放出ホルモン関連の医学的状態の処置および診断のためのミクロｒｎａおよび該ミクロｒｎａを含む組成物 |
| CN102628038A (zh) * | 2012-04-09 | 2012-08-08 | 武汉生命之美科技有限公司 | 一种改进的clip法鉴定rna结合蛋白的靶标rna的方法 |
| US20150301058A1 (en) * | 2012-11-26 | 2015-10-22 | Caris Science, Inc. | Biomarker compositions and methods |
| US10435430B2 (en) * | 2013-07-31 | 2019-10-08 | Ionis Pharmaceuticals, Inc. | Methods and compounds useful in conditions related to repeat expansion |
| US10131902B2 (en) | 2013-11-27 | 2018-11-20 | Sigma-Aldrich Co. Llc | Micro RNA isolation from biological fluid |
| US20160289734A1 (en) * | 2015-04-03 | 2016-10-06 | University Of Massachusetts | Methods of using oligonucleotide-guided argonaute proteins |
-
2014
- 2014-11-25 US US15/038,967 patent/US10131902B2/en active Active
- 2014-11-25 JP JP2016534708A patent/JP6644686B2/ja active Active
- 2014-11-25 CN CN201910746637.8A patent/CN110511924B/zh active Active
- 2014-11-25 CN CN201480074125.7A patent/CN105934439B/zh active Active
- 2014-11-25 ES ES14872184T patent/ES2778223T3/es active Active
- 2014-11-25 EP EP20152748.8A patent/EP3702361B1/en active Active
- 2014-11-25 EP EP14872184.8A patent/EP3074413B1/en active Active
- 2014-11-25 BR BR112016011770-0A patent/BR112016011770B1/pt active IP Right Grant
- 2014-11-25 CA CA2930704A patent/CA2930704C/en active Active
- 2014-11-25 WO PCT/US2014/067321 patent/WO2015094609A1/en not_active Ceased
- 2014-11-25 KR KR1020167015578A patent/KR102181103B1/ko active Active
- 2014-11-25 ES ES20152748T patent/ES2930344T3/es active Active
-
2016
- 2016-05-15 IL IL245646A patent/IL245646B/en active IP Right Grant
-
2018
- 2018-10-15 US US16/160,363 patent/US10711266B2/en active Active
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