JP2015520667A5 - - Google Patents
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- Publication number
- JP2015520667A5 JP2015520667A5 JP2015507400A JP2015507400A JP2015520667A5 JP 2015520667 A5 JP2015520667 A5 JP 2015520667A5 JP 2015507400 A JP2015507400 A JP 2015507400A JP 2015507400 A JP2015507400 A JP 2015507400A JP 2015520667 A5 JP2015520667 A5 JP 2015520667A5
- Authority
- JP
- Japan
- Prior art keywords
- purifying
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12002828.7A EP2656892A1 (en) | 2012-04-23 | 2012-04-23 | Chromatography method |
| EP12002828.7 | 2012-04-23 | ||
| US201261666453P | 2012-06-29 | 2012-06-29 | |
| US61/666,453 | 2012-06-29 | ||
| PCT/EP2013/000910 WO2013159858A1 (en) | 2012-04-23 | 2013-03-26 | Chromatography method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015520667A JP2015520667A (ja) | 2015-07-23 |
| JP2015520667A5 true JP2015520667A5 (enExample) | 2016-05-19 |
Family
ID=46052507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015507400A Pending JP2015520667A (ja) | 2012-04-23 | 2013-03-26 | クロマトグラフィー法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9149738B2 (enExample) |
| EP (2) | EP2656892A1 (enExample) |
| JP (1) | JP2015520667A (enExample) |
| KR (1) | KR102070566B1 (enExample) |
| ES (1) | ES2855182T3 (enExample) |
| WO (1) | WO2013159858A1 (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2682168A1 (en) | 2012-07-02 | 2014-01-08 | Millipore Corporation | Purification of biological molecules |
| RU2768003C2 (ru) | 2013-03-08 | 2022-03-22 | Джензим Корпорейшн | Интегрированное непрерывное производство терапевтических белковых лекарственных веществ |
| TWI709569B (zh) | 2014-01-17 | 2020-11-11 | 美商健臻公司 | 無菌層析樹脂及其用於製造方法的用途 |
| TWI671312B (zh) * | 2014-01-17 | 2019-09-11 | 美商健臻公司 | 無菌層析法及製法 |
| GB201401010D0 (en) * | 2014-01-21 | 2014-03-05 | Nat Nuclear Lab Ltd | Improved separation apparatus and method |
| DK3102935T3 (da) * | 2014-02-07 | 2021-04-06 | Cmc Biologics As | Bioreaktoranordning og fremgangsmåde til fremstilling af en biopolymer |
| FR3018450B1 (fr) | 2014-03-11 | 2016-04-15 | Lab Francais Du Fractionnement | Procede de preparation de proteines plasmatiques humaines |
| NZ724826A (en) | 2014-04-16 | 2022-07-29 | Cmc Biologics As | A high cell density fill and draw fermentation process |
| CA2951408A1 (en) * | 2014-06-25 | 2015-12-30 | Jhl Biotech, Inc. | Methods and reagents for purification of proteins |
| US11566082B2 (en) | 2014-11-17 | 2023-01-31 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| US10926191B2 (en) * | 2014-12-12 | 2021-02-23 | Cytiva Sweden Ab | System for preparing solutions for chromatography |
| EP3037513A1 (de) * | 2015-05-13 | 2016-06-29 | Bayer Technology Services GmbH | Verfahren zur kontinuierlichen elution eines produktes von chromatographiesäulen |
| US11835501B2 (en) | 2015-07-13 | 2023-12-05 | Sartorius Stedim Chromatography Systems Ltd. | Optimizing operating binding capacity for a multiple column chromatography process |
| GB201515339D0 (en) * | 2015-08-28 | 2015-10-14 | Ge Healthcare Bio Sciences Ab | A seperation matrix and a method of seperating antibodies |
| US10730908B2 (en) | 2016-05-11 | 2020-08-04 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| US10703774B2 (en) | 2016-09-30 | 2020-07-07 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| JP7031934B2 (ja) | 2016-05-11 | 2022-03-08 | サイティバ・バイオプロセス・アールアンドディ・アクチボラグ | 分離マトリックス |
| US10889615B2 (en) | 2016-05-11 | 2021-01-12 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| WO2017194592A1 (en) | 2016-05-11 | 2017-11-16 | Ge Healthcare Bioprocess R&D Ab | Method of storing a separation matrix |
| JP6987424B2 (ja) | 2016-05-11 | 2022-01-05 | サイティバ・バイオプロセス・アールアンドディ・アクチボラグ | 分離マトリックスを洗浄および／または消毒する方法 |
| EP3455243B1 (en) | 2016-05-11 | 2021-03-24 | Cytiva BioProcess R&D AB | Separation matrix |
| US10654887B2 (en) | 2016-05-11 | 2020-05-19 | Ge Healthcare Bio-Process R&D Ab | Separation matrix |
| EP3513170A4 (en) * | 2016-09-17 | 2020-07-01 | C Technologies | MONITORING OF COMPOUNDS |
| US12448411B2 (en) | 2016-09-30 | 2025-10-21 | Cytiva Bioprocess R&D Ab | Separation method |
| GB201622343D0 (en) * | 2016-12-29 | 2017-02-15 | Ge Healthcare Bio Sciences Ab | Method in bioprocess purification system |
| EP3573734B1 (en) * | 2017-01-30 | 2025-03-12 | Regeneron Pharmaceuticals, Inc. | Method for reducing bioburden in chromatography |
| GB201703116D0 (en) * | 2017-02-27 | 2017-04-12 | Ge Healthcare Bioprocess R&D Ab | A seperation matrix and a method of seperating antibodies |
| EP3381529A1 (fr) | 2017-03-29 | 2018-10-03 | EMD Millipore Corporation | Installation de traitement de liquide biologique |
| EP3381530A1 (fr) | 2017-03-29 | 2018-10-03 | EMD Millipore Corporation | Installation de traitement de liquide biologique |
| GB201710130D0 (en) | 2017-06-26 | 2017-08-09 | Ge Healthcare Bioprocess R & D Ab | A Method of seperation |
| CN107793469B (zh) * | 2017-10-16 | 2021-07-30 | 上海药明生物技术有限公司 | 一种去除宿主细胞蛋白含量的亲和纯化工艺 |
| GB201806752D0 (en) * | 2018-04-25 | 2018-06-06 | Ge Healthcare Bioprocess R&D Ab | Method in bioprocess system |
| GB201810772D0 (en) | 2018-06-29 | 2018-08-15 | Ge Healthcare Bio Sciences Ab | Method in bioprocess purification system |
| TW202448568A (zh) * | 2018-07-02 | 2024-12-16 | 美商里珍納龍藥品有限公司 | 自混合物製備多肽之系統及方法 |
| BR112021002724A2 (pt) * | 2018-08-17 | 2021-07-20 | Regeneron Pharmaceuticals, Inc. | método para quantificar uma quantidade de um anticorpo heterodimérico, e, sistema de cromatografia |
| CN112638488A (zh) | 2018-08-31 | 2021-04-09 | 建新公司 | 灭菌的层析树脂及其在制造工艺中的用途 |
| US10981950B2 (en) * | 2019-01-31 | 2021-04-20 | Joanna Pezzini | Therapeutic protein flow kit for a continuous purification system |
| TWI870412B (zh) * | 2019-06-05 | 2025-01-21 | 美商建南德克公司 | 過載層析管柱之再生方法 |
| FR3099066B1 (fr) | 2019-07-26 | 2021-08-13 | Novasep Process | Procédé de purification d’une substance cible avec inactivation virale |
| US11906510B2 (en) * | 2020-03-20 | 2024-02-20 | Stanford Junior University | Metabolic profiling by reverse-phase/ion-exchange mass spectrometry |
| KR20220158004A (ko) | 2020-03-25 | 2022-11-29 | 메르크 파텐트 게엠베하 | 단백질 정제를 위한 인테인-결합 수지의 재사용 |
| US20230406881A1 (en) * | 2020-11-20 | 2023-12-21 | Ares Trading S.A. | Buffers and methods for purifying proteins |
| KR20240046607A (ko) | 2021-09-28 | 2024-04-09 | 메르크 파텐트 게엠베하 | 연속 크로마토그래피 작업 동안의 크로마토그래피 수지의 모니터링 방법 |
| KR20240054316A (ko) | 2021-09-28 | 2024-04-25 | 메르크 파텐트 게엠베하 | 인라인 지속적 가압 탱크： “ｉｃｐｔ”를 사용한 공정 강화를 위한 통합 솔루션 |
| CN115006884B (zh) * | 2022-06-28 | 2023-08-15 | 江南大学 | 一种在线解耦式模拟移动床分离系统及其分离木糖和阿拉伯糖的方法 |
| US20250041760A1 (en) * | 2023-07-31 | 2025-02-06 | Agilent Technologies, Inc. | Column comprising particles |
| WO2025031868A1 (en) | 2023-08-08 | 2025-02-13 | Cytiva Sweden Ab | Multi modular chromatography system |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3478325B2 (ja) * | 1997-12-25 | 2003-12-15 | オルガノ株式会社 | クロマト分離方法 |
| JP4603114B2 (ja) * | 1999-09-07 | 2010-12-22 | オルガノ株式会社 | 液体に含まれる複数成分を分離する方法及び装置 |
| US7691645B2 (en) * | 2001-01-09 | 2010-04-06 | Agilent Technologies, Inc. | Immunosubtraction method |
| US20080312425A1 (en) * | 2004-08-30 | 2008-12-18 | Lonza Biologics Plc. | Ion Exchange Chromatography and Purification of Antibodies |
| CN102417557B (zh) | 2005-08-03 | 2015-03-11 | 默克专利股份公司 | 亲水交联聚合物 |
| EP1775001A1 (en) * | 2005-10-13 | 2007-04-18 | Xendo Holding B.V. | Device for chromatographic separations |
| WO2007144476A1 (fr) | 2006-06-16 | 2007-12-21 | Groupe Novasep | Procede de separation sequence multicolonnes |
| US8569464B2 (en) | 2006-12-21 | 2013-10-29 | Emd Millipore Corporation | Purification of proteins |
| US8362217B2 (en) | 2006-12-21 | 2013-01-29 | Emd Millipore Corporation | Purification of proteins |
| WO2008079280A1 (en) | 2006-12-21 | 2008-07-03 | Millipore Corporation | Purification of proteins |
| NZ577933A (en) | 2007-01-22 | 2011-12-22 | Genentech Inc | Polyelectrolyte precipitation and purification of antibodies |
| WO2008153472A1 (en) * | 2007-06-15 | 2008-12-18 | Ge Healthcare Bio-Sciences Ab | Chromatography method |
| US7618539B2 (en) | 2008-03-31 | 2009-11-17 | Ampac Fine Chemicals Llc | Simulated moving bed chromatography for strongly retained compounds |
| WO2010035757A1 (ja) * | 2008-09-25 | 2010-04-01 | Jsr株式会社 | アフィニティークロマトグラフィー用充填剤 |
| CN102256993A (zh) | 2008-12-16 | 2011-11-23 | 米利波尔公司 | 蛋白的纯化 |
| JP5354094B2 (ja) * | 2010-03-31 | 2013-11-27 | Ｊｓｒ株式会社 | アフィニティークロマトグラフィー用充填剤 |
| CN101948399A (zh) * | 2010-10-11 | 2011-01-19 | 江南大学 | 一种使用模拟移动床色谱连续分离纯化发酵液中缬氨酸的方法 |
-
2012
- 2012-04-23 EP EP12002828.7A patent/EP2656892A1/en not_active Withdrawn
-
2013
- 2013-03-26 KR KR1020147032736A patent/KR102070566B1/ko active Active
- 2013-03-26 WO PCT/EP2013/000910 patent/WO2013159858A1/en not_active Ceased
- 2013-03-26 JP JP2015507400A patent/JP2015520667A/ja active Pending
- 2013-03-26 EP EP13713084.5A patent/EP2841176B1/en active Active
- 2013-03-26 ES ES13713084T patent/ES2855182T3/es active Active
- 2013-04-19 US US13/866,060 patent/US9149738B2/en active Active
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