JP2015520667A5 - - Google Patents
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- Publication number
- JP2015520667A5 JP2015520667A5 JP2015507400A JP2015507400A JP2015520667A5 JP 2015520667 A5 JP2015520667 A5 JP 2015520667A5 JP 2015507400 A JP2015507400 A JP 2015507400A JP 2015507400 A JP2015507400 A JP 2015507400A JP 2015520667 A5 JP2015520667 A5 JP 2015520667A5
- Authority
- JP
- Japan
- Prior art keywords
- purifying
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12002828.7 | 2012-04-23 | ||
| EP12002828.7A EP2656892A1 (en) | 2012-04-23 | 2012-04-23 | Chromatography method |
| US201261666453P | 2012-06-29 | 2012-06-29 | |
| US61/666,453 | 2012-06-29 | ||
| PCT/EP2013/000910 WO2013159858A1 (en) | 2012-04-23 | 2013-03-26 | Chromatography method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015520667A JP2015520667A (ja) | 2015-07-23 |
| JP2015520667A5 true JP2015520667A5 (enExample) | 2016-05-19 |
Family
ID=46052507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015507400A Pending JP2015520667A (ja) | 2012-04-23 | 2013-03-26 | クロマトグラフィー法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9149738B2 (enExample) |
| EP (2) | EP2656892A1 (enExample) |
| JP (1) | JP2015520667A (enExample) |
| KR (1) | KR102070566B1 (enExample) |
| ES (1) | ES2855182T3 (enExample) |
| WO (1) | WO2013159858A1 (enExample) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2682168A1 (en) | 2012-07-02 | 2014-01-08 | Millipore Corporation | Purification of biological molecules |
| US9650412B2 (en) | 2013-03-08 | 2017-05-16 | Genzyme Corporation | Integrated continuous manufacturing of therapeutic protein drug substances |
| TWI709569B (zh) | 2014-01-17 | 2020-11-11 | 美商健臻公司 | 無菌層析樹脂及其用於製造方法的用途 |
| TWI671312B (zh) * | 2014-01-17 | 2019-09-11 | 美商健臻公司 | 無菌層析法及製法 |
| GB201401010D0 (en) * | 2014-01-21 | 2014-03-05 | Nat Nuclear Lab Ltd | Improved separation apparatus and method |
| ES2864721T3 (es) | 2014-02-07 | 2021-10-14 | Cmc Biologics As | Disposición y proceso continuo de un biorreactor para la producción y captura de un biopolímero |
| FR3018450B1 (fr) | 2014-03-11 | 2016-04-15 | Lab Francais Du Fractionnement | Procede de preparation de proteines plasmatiques humaines |
| US10844345B2 (en) | 2014-04-16 | 2020-11-24 | Cmc Biologics A/S | High density fill and draw fermentation process |
| KR20170026521A (ko) * | 2014-06-25 | 2017-03-08 | 제이에이치엘 바이오테크 인코포레이티드 | 단백질의 정제를 위한 방법 및 시약 |
| US11566082B2 (en) | 2014-11-17 | 2023-01-31 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| EP3230729B1 (en) * | 2014-12-12 | 2024-03-06 | Cytiva Sweden AB | System for preparing solutions for chromatography |
| EP3037513A1 (de) * | 2015-05-13 | 2016-06-29 | Bayer Technology Services GmbH | Verfahren zur kontinuierlichen elution eines produktes von chromatographiesäulen |
| US11835501B2 (en) | 2015-07-13 | 2023-12-05 | Sartorius Stedim Chromatography Systems Ltd. | Optimizing operating binding capacity for a multiple column chromatography process |
| GB201515339D0 (en) | 2015-08-28 | 2015-10-14 | Ge Healthcare Bio Sciences Ab | A seperation matrix and a method of seperating antibodies |
| US10654887B2 (en) | 2016-05-11 | 2020-05-19 | Ge Healthcare Bio-Process R&D Ab | Separation matrix |
| US10513537B2 (en) | 2016-05-11 | 2019-12-24 | Ge Healthcare Bioprocess R&D Ab | Separation matrix |
| CN109311949B (zh) | 2016-05-11 | 2022-09-16 | 思拓凡生物工艺研发有限公司 | 储存分离基质的方法 |
| US10889615B2 (en) | 2016-05-11 | 2021-01-12 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| JP7031934B2 (ja) | 2016-05-11 | 2022-03-08 | サイティバ・バイオプロセス・アールアンドディ・アクチボラグ | 分離マトリックス |
| US10703774B2 (en) | 2016-09-30 | 2020-07-07 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| WO2017194593A1 (en) | 2016-05-11 | 2017-11-16 | Ge Healthcare Bioprocess R&D Ab | Method of cleaning and/or sanitizing a separation matrix |
| US10730908B2 (en) | 2016-05-11 | 2020-08-04 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| EP3513170A4 (en) * | 2016-09-17 | 2020-07-01 | C Technologies | MONITORING OF COMPOUNDS |
| US12448411B2 (en) | 2016-09-30 | 2025-10-21 | Cytiva Bioprocess R&D Ab | Separation method |
| GB201622343D0 (en) * | 2016-12-29 | 2017-02-15 | Ge Healthcare Bio Sciences Ab | Method in bioprocess purification system |
| KR102586771B1 (ko) * | 2017-01-30 | 2023-10-11 | 리제너론 파마슈티칼스 인코포레이티드 | 크로마토그래피에서 바이오버든을 감소시키기 위한 조성물 및 방법 |
| GB201703116D0 (en) | 2017-02-27 | 2017-04-12 | Ge Healthcare Bioprocess R&D Ab | A seperation matrix and a method of seperating antibodies |
| EP3381529A1 (fr) * | 2017-03-29 | 2018-10-03 | EMD Millipore Corporation | Installation de traitement de liquide biologique |
| EP3381530A1 (fr) * | 2017-03-29 | 2018-10-03 | EMD Millipore Corporation | Installation de traitement de liquide biologique |
| GB201710130D0 (en) | 2017-06-26 | 2017-08-09 | Ge Healthcare Bioprocess R & D Ab | A Method of seperation |
| CN107793469B (zh) * | 2017-10-16 | 2021-07-30 | 上海药明生物技术有限公司 | 一种去除宿主细胞蛋白含量的亲和纯化工艺 |
| GB201806752D0 (en) * | 2018-04-25 | 2018-06-06 | Ge Healthcare Bioprocess R&D Ab | Method in bioprocess system |
| GB201810772D0 (en) | 2018-06-29 | 2018-08-15 | Ge Healthcare Bio Sciences Ab | Method in bioprocess purification system |
| TWI853823B (zh) * | 2018-07-02 | 2024-09-01 | 美商里珍納龍藥品有限公司 | 自混合物製備多肽之系統及方法 |
| US12152056B2 (en) * | 2018-08-17 | 2024-11-26 | Regeneron Pharmaceuticals, Inc. | Method and chromatography system for determining amount and purity of a multimeric protein |
| AU2019332764B2 (en) | 2018-08-31 | 2025-05-29 | Genzyme Corporation | Sterile chromatography resin and use thereof in manufacturing processes |
| US10981950B2 (en) * | 2019-01-31 | 2021-04-20 | Joanna Pezzini | Therapeutic protein flow kit for a continuous purification system |
| TWI870412B (zh) * | 2019-06-05 | 2025-01-21 | 美商建南德克公司 | 過載層析管柱之再生方法 |
| FR3099066B1 (fr) | 2019-07-26 | 2021-08-13 | Novasep Process | Procédé de purification d’une substance cible avec inactivation virale |
| US11906510B2 (en) * | 2020-03-20 | 2024-02-20 | Stanford Junior University | Metabolic profiling by reverse-phase/ion-exchange mass spectrometry |
| EP4126899A1 (en) | 2020-03-25 | 2023-02-08 | Merck Patent GmbH | Reuse of intein-bound resins for protein purification |
| CN116829569A (zh) * | 2020-11-20 | 2023-09-29 | 阿雷斯贸易股份有限公司 | 蛋白质纯化缓冲液和方法 |
| CN117043173A (zh) * | 2021-03-10 | 2023-11-10 | 美国安进公司 | 重组蛋白的纯化方法 |
| KR20240046607A (ko) | 2021-09-28 | 2024-04-09 | 메르크 파텐트 게엠베하 | 연속 크로마토그래피 작업 동안의 크로마토그래피 수지의 모니터링 방법 |
| CA3233651A1 (en) | 2021-09-28 | 2023-04-06 | Merck Patent Gmbh | Integrated solution for process intensification using inline constantly pressurized tank: "icpt" |
| CN115006884B (zh) * | 2022-06-28 | 2023-08-15 | 江南大学 | 一种在线解耦式模拟移动床分离系统及其分离木糖和阿拉伯糖的方法 |
| US20250041760A1 (en) * | 2023-07-31 | 2025-02-06 | Agilent Technologies, Inc. | Column comprising particles |
| CN121666533A (zh) | 2023-08-08 | 2026-03-13 | 思拓凡瑞典有限公司 | 多模块色谱系统 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3478325B2 (ja) * | 1997-12-25 | 2003-12-15 | オルガノ株式会社 | クロマト分離方法 |
| JP4603114B2 (ja) * | 1999-09-07 | 2010-12-22 | オルガノ株式会社 | 液体に含まれる複数成分を分離する方法及び装置 |
| US7691645B2 (en) * | 2001-01-09 | 2010-04-06 | Agilent Technologies, Inc. | Immunosubtraction method |
| EP1685161A1 (en) * | 2004-08-30 | 2006-08-02 | Lonza Biologics plc | Affinity- plus ion exchange-chromatography for purifying antibodies |
| CN101258175B (zh) | 2005-08-03 | 2011-11-16 | 默克专利股份公司 | 亲水交联聚合物 |
| EP1775001A1 (en) * | 2005-10-13 | 2007-04-18 | Xendo Holding B.V. | Device for chromatographic separations |
| WO2007144476A1 (fr) | 2006-06-16 | 2007-12-21 | Groupe Novasep | Procede de separation sequence multicolonnes |
| US8163886B2 (en) | 2006-12-21 | 2012-04-24 | Emd Millipore Corporation | Purification of proteins |
| US8569464B2 (en) | 2006-12-21 | 2013-10-29 | Emd Millipore Corporation | Purification of proteins |
| US8362217B2 (en) | 2006-12-21 | 2013-01-29 | Emd Millipore Corporation | Purification of proteins |
| MX2009007632A (es) | 2007-01-22 | 2009-07-24 | Genentech Inc | Precipitacion de polielectrolito y purificacion de proteinas. |
| US7901581B2 (en) * | 2007-06-15 | 2011-03-08 | Ge Healthcare Bio-Sciences Ab | Chromatography method |
| US7618539B2 (en) | 2008-03-31 | 2009-11-17 | Ampac Fine Chemicals Llc | Simulated moving bed chromatography for strongly retained compounds |
| CN102165312B (zh) * | 2008-09-25 | 2015-04-22 | Jsr株式会社 | 亲合层析用填充剂 |
| US20110020327A1 (en) | 2008-12-16 | 2011-01-27 | Millipore Corporation | Purification of proteins |
| JP5354094B2 (ja) * | 2010-03-31 | 2013-11-27 | Ｊｓｒ株式会社 | アフィニティークロマトグラフィー用充填剤 |
| CN101948399A (zh) * | 2010-10-11 | 2011-01-19 | 江南大学 | 一种使用模拟移动床色谱连续分离纯化发酵液中缬氨酸的方法 |
-
2012
- 2012-04-23 EP EP12002828.7A patent/EP2656892A1/en not_active Withdrawn
-
2013
- 2013-03-26 KR KR1020147032736A patent/KR102070566B1/ko active Active
- 2013-03-26 JP JP2015507400A patent/JP2015520667A/ja active Pending
- 2013-03-26 WO PCT/EP2013/000910 patent/WO2013159858A1/en not_active Ceased
- 2013-03-26 ES ES13713084T patent/ES2855182T3/es active Active
- 2013-03-26 EP EP13713084.5A patent/EP2841176B1/en active Active
- 2013-04-19 US US13/866,060 patent/US9149738B2/en active Active
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