JP2015520667A5 - - Google Patents
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- Publication number
- JP2015520667A5 JP2015520667A5 JP2015507400A JP2015507400A JP2015520667A5 JP 2015520667 A5 JP2015520667 A5 JP 2015520667A5 JP 2015507400 A JP2015507400 A JP 2015507400A JP 2015507400 A JP2015507400 A JP 2015507400A JP 2015520667 A5 JP2015520667 A5 JP 2015520667A5
- Authority
- JP
- Japan
- Prior art keywords
- purifying
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
Claims (1)
- 請求項1〜10のいずれか一項に記載の方法を含む、タンパク質を精製するためのプロセス。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12002828.7 | 2012-04-23 | ||
EP12002828.7A EP2656892A1 (en) | 2012-04-23 | 2012-04-23 | Chromatography method |
US201261666453P | 2012-06-29 | 2012-06-29 | |
US61/666,453 | 2012-06-29 | ||
PCT/EP2013/000910 WO2013159858A1 (en) | 2012-04-23 | 2013-03-26 | Chromatography method |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2015520667A JP2015520667A (ja) | 2015-07-23 |
JP2015520667A5 true JP2015520667A5 (ja) | 2016-05-19 |
Family
ID=46052507
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2015507400A Pending JP2015520667A (ja) | 2012-04-23 | 2013-03-26 | クロマトグラフィー法 |
Country Status (6)
Country | Link |
---|---|
US (1) | US9149738B2 (ja) |
EP (2) | EP2656892A1 (ja) |
JP (1) | JP2015520667A (ja) |
KR (1) | KR102070566B1 (ja) |
ES (1) | ES2855182T3 (ja) |
WO (1) | WO2013159858A1 (ja) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2682168A1 (en) | 2012-07-02 | 2014-01-08 | Millipore Corporation | Purification of biological molecules |
MX2015012114A (es) | 2013-03-08 | 2016-01-12 | Genzyme Corp | Fabricacion continua integrada de principios activos proteinicos terapeuticos. |
TWI709569B (zh) | 2014-01-17 | 2020-11-11 | 美商健臻公司 | 無菌層析樹脂及其用於製造方法的用途 |
TWI709570B (zh) | 2014-01-17 | 2020-11-11 | 美商健臻公司 | 無菌層析法及製法 |
GB201401010D0 (en) * | 2014-01-21 | 2014-03-05 | Nat Nuclear Lab Ltd | Improved separation apparatus and method |
WO2015117883A1 (en) * | 2014-02-07 | 2015-08-13 | Cmc Biologics A/S | A bioreactor arrangement and continuous process for producing and capturing a biopolymer |
FR3018450B1 (fr) | 2014-03-11 | 2016-04-15 | Lab Francais Du Fractionnement | Procede de preparation de proteines plasmatiques humaines |
JP6758194B2 (ja) | 2014-04-16 | 2020-09-23 | シーエムシー バイオロジックス エー/エス | 高細胞密度フィル・アンド・ドロー発酵プロセス |
CA2951408A1 (en) | 2014-06-25 | 2015-12-30 | Jhl Biotech, Inc. | Methods and reagents for purification of proteins |
US11566082B2 (en) | 2014-11-17 | 2023-01-31 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
WO2016092023A1 (en) * | 2014-12-12 | 2016-06-16 | Ge Healthcare Bio-Sciences Ab | System for preparing solutions for chromatography |
EP3037513A1 (de) * | 2015-05-13 | 2016-06-29 | Bayer Technology Services GmbH | Verfahren zur kontinuierlichen elution eines produktes von chromatographiesäulen |
US11835501B2 (en) | 2015-07-13 | 2023-12-05 | Sartorius Stedim Chromatography Systems Ltd. | Optimizing operating binding capacity for a multiple column chromatography process |
GB201515339D0 (en) | 2015-08-28 | 2015-10-14 | Ge Healthcare Bio Sciences Ab | A seperation matrix and a method of seperating antibodies |
WO2017194597A1 (en) | 2016-05-11 | 2017-11-16 | Ge Healthcare Bioprocess R&D Ab | Separation matrix |
US10730908B2 (en) | 2016-05-11 | 2020-08-04 | Ge Healthcare Bioprocess R&D Ab | Separation method |
EP3455241B1 (en) | 2016-05-11 | 2022-02-23 | Cytiva BioProcess R&D AB | Method of cleaning and/or sanitizing a separation matrix |
CN109311949B (zh) | 2016-05-11 | 2022-09-16 | 思拓凡生物工艺研发有限公司 | 储存分离基质的方法 |
US10654887B2 (en) | 2016-05-11 | 2020-05-19 | Ge Healthcare Bio-Process R&D Ab | Separation matrix |
US10889615B2 (en) | 2016-05-11 | 2021-01-12 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
US10703774B2 (en) | 2016-09-30 | 2020-07-07 | Ge Healthcare Bioprocess R&D Ab | Separation method |
EP3513170A4 (en) * | 2016-09-17 | 2020-07-01 | C Technologies | MONITORING OF COMPOUNDS |
GB201622343D0 (en) * | 2016-12-29 | 2017-02-15 | Ge Healthcare Bio Sciences Ab | Method in bioprocess purification system |
WO2018140887A1 (en) * | 2017-01-30 | 2018-08-02 | Regeneron Pharmaceuticals, Inc. | Method for reducing bioburden in chromatography |
GB201703116D0 (en) * | 2017-02-27 | 2017-04-12 | Ge Healthcare Bioprocess R&D Ab | A seperation matrix and a method of seperating antibodies |
EP3381529A1 (fr) * | 2017-03-29 | 2018-10-03 | EMD Millipore Corporation | Installation de traitement de liquide biologique |
EP3381530A1 (fr) * | 2017-03-29 | 2018-10-03 | EMD Millipore Corporation | Installation de traitement de liquide biologique |
GB201710130D0 (en) | 2017-06-26 | 2017-08-09 | Ge Healthcare Bioprocess R & D Ab | A Method of seperation |
CN107793469B (zh) * | 2017-10-16 | 2021-07-30 | 上海药明生物技术有限公司 | 一种去除宿主细胞蛋白含量的亲和纯化工艺 |
TW202005694A (zh) * | 2018-07-02 | 2020-02-01 | 美商里珍納龍藥品有限公司 | 自混合物製備多肽之系統及方法 |
WO2020037182A1 (en) * | 2018-08-17 | 2020-02-20 | Regeneron Pharmaceuticals, Inc. | Method and chromatography system for determining amount and purity of a multimeric protein |
JP2021536353A (ja) | 2018-08-31 | 2021-12-27 | ジェンザイム・コーポレーション | 無菌クロマトグラフィー樹脂および製造方法におけるその使用 |
US10981950B2 (en) * | 2019-01-31 | 2021-04-20 | Joanna Pezzini | Therapeutic protein flow kit for a continuous purification system |
FR3099066B1 (fr) | 2019-07-26 | 2021-08-13 | Novasep Process | Procédé de purification d’une substance cible avec inactivation virale |
US11906510B2 (en) * | 2020-03-20 | 2024-02-20 | Stanford Junior University | Metabolic profiling by reverse-phase/ion-exchange mass spectrometry |
CN117980740A (zh) | 2021-09-28 | 2024-05-03 | 默克专利股份有限公司 | 用于在连续色谱操作过程中监测色谱树脂的方法 |
CN117957050A (zh) | 2021-09-28 | 2024-04-30 | 默克专利股份有限公司 | 用于使用直列式恒压罐“icpt”进行处理强化的集成解决方案 |
CN115006884B (zh) * | 2022-06-28 | 2023-08-15 | 江南大学 | 一种在线解耦式模拟移动床分离系统及其分离木糖和阿拉伯糖的方法 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3478325B2 (ja) * | 1997-12-25 | 2003-12-15 | オルガノ株式会社 | クロマト分離方法 |
JP4603114B2 (ja) * | 1999-09-07 | 2010-12-22 | オルガノ株式会社 | 液体に含まれる複数成分を分離する方法及び装置 |
US7691645B2 (en) * | 2001-01-09 | 2010-04-06 | Agilent Technologies, Inc. | Immunosubtraction method |
WO2006024497A1 (en) * | 2004-08-30 | 2006-03-09 | Lonza Biologics Plc. | Affinity- plus ion exchange- chromatography for purifying antibodies |
JP5475284B2 (ja) | 2005-08-03 | 2014-04-16 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 親水性架橋ポリマー |
EP1775001A1 (en) * | 2005-10-13 | 2007-04-18 | Xendo Holding B.V. | Device for chromatographic separations |
WO2007144476A1 (fr) | 2006-06-16 | 2007-12-21 | Groupe Novasep | Procede de separation sequence multicolonnes |
US8362217B2 (en) | 2006-12-21 | 2013-01-29 | Emd Millipore Corporation | Purification of proteins |
WO2008079302A2 (en) | 2006-12-21 | 2008-07-03 | Millipore Corporation | Purification of proteins |
US8569464B2 (en) | 2006-12-21 | 2013-10-29 | Emd Millipore Corporation | Purification of proteins |
US7947813B2 (en) | 2007-01-22 | 2011-05-24 | Genentech, Inc. | Polyelectrolyte precipitation and purification of proteins |
CN101687119B (zh) * | 2007-06-15 | 2013-06-12 | 通用电气健康护理生物科学股份公司 | 色谱方法 |
US7618539B2 (en) * | 2008-03-31 | 2009-11-17 | Ampac Fine Chemicals Llc | Simulated moving bed chromatography for strongly retained compounds |
US8846877B2 (en) * | 2008-09-25 | 2014-09-30 | Jsr Corporation | Packing material for affinity chromatography |
US20110020327A1 (en) | 2008-12-16 | 2011-01-27 | Millipore Corporation | Purification of proteins |
KR20130055569A (ko) * | 2010-03-31 | 2013-05-28 | 제이에스알 가부시끼가이샤 | 친화성 크로마토그래피용 충전제 |
CN101948399A (zh) * | 2010-10-11 | 2011-01-19 | 江南大学 | 一种使用模拟移动床色谱连续分离纯化发酵液中缬氨酸的方法 |
-
2012
- 2012-04-23 EP EP12002828.7A patent/EP2656892A1/en not_active Withdrawn
-
2013
- 2013-03-26 ES ES13713084T patent/ES2855182T3/es active Active
- 2013-03-26 KR KR1020147032736A patent/KR102070566B1/ko active IP Right Grant
- 2013-03-26 JP JP2015507400A patent/JP2015520667A/ja active Pending
- 2013-03-26 WO PCT/EP2013/000910 patent/WO2013159858A1/en active Application Filing
- 2013-03-26 EP EP13713084.5A patent/EP2841176B1/en active Active
- 2013-04-19 US US13/866,060 patent/US9149738B2/en active Active
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