JP2014519854A5 - - Google Patents
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- JP2014519854A5 JP2014519854A5 JP2014517255A JP2014517255A JP2014519854A5 JP 2014519854 A5 JP2014519854 A5 JP 2014519854A5 JP 2014517255 A JP2014517255 A JP 2014517255A JP 2014517255 A JP2014517255 A JP 2014517255A JP 2014519854 A5 JP2014519854 A5 JP 2014519854A5
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- Japan
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- 238000012136 culture method Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161500442P | 2011-06-23 | 2011-06-23 | |
| US61/500,442 | 2011-06-23 | ||
| PCT/US2012/044096 WO2012178215A1 (en) | 2011-06-23 | 2012-06-25 | Self-renewing endodermal progenitor lines generated from human pluripotent stem cells and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014519854A JP2014519854A (ja) | 2014-08-21 |
| JP2014519854A5 true JP2014519854A5 (enExample) | 2015-08-13 |
Family
ID=47423011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014517255A Pending JP2014519854A (ja) | 2011-06-23 | 2012-06-25 | ヒト多能性幹細胞から生じる自己複製する内胚葉前駆細胞株とその使用方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9476030B2 (enExample) |
| EP (1) | EP2723851A4 (enExample) |
| JP (1) | JP2014519854A (enExample) |
| AU (1) | AU2012272586B2 (enExample) |
| CA (1) | CA2840192A1 (enExample) |
| WO (1) | WO2012178215A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011140441A2 (en) | 2010-05-06 | 2011-11-10 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| SG10201803131TA (en) * | 2013-02-18 | 2018-06-28 | Univ Health Network | Methods for generating hepatocytes and cholangiocytes from pluripotent stem cells |
| US10266807B2 (en) | 2013-04-03 | 2019-04-23 | FUJIFILM Cellular Dynamics, Inc. | Methods and compositions for culturing endoderm progenitor cells in suspension |
| EP3712254A1 (en) | 2014-05-28 | 2020-09-23 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into gastric tissues through directed differentiation |
| WO2016061464A1 (en) | 2014-10-17 | 2016-04-21 | Children's Hospital Center, D/B/A Cincinnati Children's Hospital Medical Center | In vivo model of human small intetine using pluripotent stem cells and methods of making and using same |
| US10627415B2 (en) | 2015-03-12 | 2020-04-21 | Board Of Trustees Of Michigan State University | Compositions and methods for diagnosing, monitoring, and treating an autoimmune disease |
| CA3016641A1 (en) * | 2016-05-05 | 2017-11-09 | Children's Hospital Medical Center | Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same |
| JP7005528B2 (ja) * | 2016-06-03 | 2022-01-21 | 中国人民解放軍軍事医学科学院野戦輸血研究所 | 消化管由来上皮細胞を内胚葉幹細胞／前駆細胞に初期化するための低分子化合物の組み合わせ、初期化方法および適用 |
| KR102546194B1 (ko) | 2016-11-04 | 2023-06-21 | 칠드런즈 호스피탈 메디칼 센터 | 간 유사 장기 조성물 및 이를 제조 및 사용하는 방법 |
| KR102807995B1 (ko) | 2016-12-05 | 2025-05-16 | 칠드런즈 호스피탈 메디칼 센터 | 결장 유사장기 및 이를 제조 및 사용하는 방법 |
| EP3583201B1 (en) * | 2017-02-14 | 2024-01-17 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Methods of engineering human induced pluripotent stem cells to produce liver tissue |
| US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
| JP7248586B2 (ja) | 2017-04-14 | 2023-03-29 | チルドレンズ ホスピタル メディカル センター | 複数ドナー幹細胞組成物およびそれを作製する方法 |
| WO2019074793A1 (en) | 2017-10-10 | 2019-04-18 | Children's Hospital Medical Center | OESOPHAGIAN TISSUE COMPOSITIONS AND / OR ORGANOIDS AND METHODS OF MAKING SAME |
| WO2019126626A1 (en) | 2017-12-21 | 2019-06-27 | Children's Hospital Medical Center | Digitalized human organoids and methods of using same |
| AU2019261083B2 (en) * | 2018-04-23 | 2025-01-23 | Orizuru Therapeutics, Inc. | Growth inhibitor |
| CA3106634A1 (en) | 2018-07-26 | 2020-01-30 | Children's Hospital Medical Center | Hepato-biliary-pancreatic tissues and methods of making same |
| US12428622B2 (en) | 2018-09-12 | 2025-09-30 | Children's Hospital Medical Center | Organoid compositions for the production of hematopoietic stem cells and derivatives thereof |
| CN111394297A (zh) * | 2018-12-17 | 2020-07-10 | 中国科学院分子细胞科学卓越创新中心 | 内胚层干细胞规模化制备功能性肝母细胞与肝实质细胞的方法及其应用 |
| EP3966315A1 (en) * | 2019-05-09 | 2022-03-16 | FUJIFILM Cellular Dynamics, Inc. | Methods for the production of hepatocytes |
| WO2020245747A1 (en) * | 2019-06-04 | 2020-12-10 | University Health Network | Methods of making and using liver cells |
| CN113265373A (zh) * | 2021-07-19 | 2021-08-17 | 北京明诚创新医学研究院有限责任公司 | 一种人多能干细胞分化为肝祖细胞的培养基、方法及其应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9700983D0 (sv) * | 1997-03-18 | 1997-03-18 | Ascendia Ab | Stimulering, odling och preservation av pankreas- och andra celler |
| US20060003446A1 (en) * | 2002-05-17 | 2006-01-05 | Gordon Keller | Mesoderm and definitive endoderm cell populations |
| JP2009506769A (ja) * | 2005-09-02 | 2009-02-19 | エージェンシー フォー サイエンス，テクノロジー アンド リサーチ | 間充織幹細胞誘導方法 |
| NZ567082A (en) * | 2005-10-14 | 2012-08-31 | Univ Minnesota | Differentiation of non-embryonic stem cells to cells having a pancreatic phenotype |
| US7989204B2 (en) | 2006-04-28 | 2011-08-02 | Viacyte, Inc. | Hepatocyte lineage cells |
| WO2007143193A1 (en) * | 2006-06-02 | 2007-12-13 | University Of Georgia Research Foundation, Inc. | Pancreatic and liver endoderm cells and tissue by differentiation of definitive endoderm cells obtained from human embryonic stems |
| US9029147B2 (en) * | 2007-06-15 | 2015-05-12 | Massachusetts Institute Of Technology | Methods and compositions for enhanced differentiation from embryonic stem cells |
| CA2693156C (en) * | 2007-07-18 | 2018-03-06 | Alireza Rezania | Differentiation of human embryonic stem cells |
| CN102083967B (zh) * | 2007-07-20 | 2013-05-15 | 塞拉提斯股份公司 | 经由定型内胚层(DE-hep)衍生自人胚泡衍生干细胞的新肝细胞群体 |
| WO2009137844A2 (en) * | 2008-05-09 | 2009-11-12 | Vistagen Therapeutics, Inc. | Pancreatic endocrine progenitor cells derived from pluripotent stem cells |
| US8367316B2 (en) * | 2009-05-01 | 2013-02-05 | Alfagene Bioscience, Inc. | Human gastrointestinal stem cell-derived primary intestinal epithelial cell system and methods of use thereof |
| WO2011005326A1 (en) * | 2009-07-09 | 2011-01-13 | Massachusetts Institute Of Technology | Methods and compositions for increased safety of stem cell-derived populations |
| SG10201407102QA (en) * | 2009-10-30 | 2014-11-27 | Univ North Carolina | Multipotent stem cells from the extrahepatic billary tree and methods of isolating same |
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2012
- 2012-06-25 JP JP2014517255A patent/JP2014519854A/ja active Pending
- 2012-06-25 CA CA2840192A patent/CA2840192A1/en not_active Abandoned
- 2012-06-25 AU AU2012272586A patent/AU2012272586B2/en not_active Ceased
- 2012-06-25 EP EP12802203.5A patent/EP2723851A4/en not_active Withdrawn
- 2012-06-25 WO PCT/US2012/044096 patent/WO2012178215A1/en not_active Ceased
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2013
- 2013-12-23 US US14/138,963 patent/US9476030B2/en not_active Expired - Fee Related