JP2014519854A5 - - Google Patents
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- JP2014519854A5 JP2014519854A5 JP2014517255A JP2014517255A JP2014519854A5 JP 2014519854 A5 JP2014519854 A5 JP 2014519854A5 JP 2014517255 A JP2014517255 A JP 2014517255A JP 2014517255 A JP2014517255 A JP 2014517255A JP 2014519854 A5 JP2014519854 A5 JP 2014519854A5
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- Japan
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- patent document
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- 238000012136 culture method Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161500442P | 2011-06-23 | 2011-06-23 | |
| US61/500,442 | 2011-06-23 | ||
| PCT/US2012/044096 WO2012178215A1 (en) | 2011-06-23 | 2012-06-25 | Self-renewing endodermal progenitor lines generated from human pluripotent stem cells and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014519854A JP2014519854A (ja) | 2014-08-21 |
| JP2014519854A5 true JP2014519854A5 (enExample) | 2015-08-13 |
Family
ID=47423011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014517255A Pending JP2014519854A (ja) | 2011-06-23 | 2012-06-25 | ヒト多能性幹細胞から生じる自己複製する内胚葉前駆細胞株とその使用方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9476030B2 (enExample) |
| EP (1) | EP2723851A4 (enExample) |
| JP (1) | JP2014519854A (enExample) |
| AU (1) | AU2012272586B2 (enExample) |
| CA (1) | CA2840192A1 (enExample) |
| WO (1) | WO2012178215A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9719068B2 (en) | 2010-05-06 | 2017-08-01 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| SG11201506520TA (en) * | 2013-02-18 | 2015-09-29 | Univ Health Network | Methods for generating hepatocytes and cholangiocytes from pluripotent stem cells |
| WO2014165663A1 (en) * | 2013-04-03 | 2014-10-09 | Cellular Dynamics International, Inc. | Methods and compositions for culturing endoderm progenitor cells in suspension |
| SG10201801654RA (en) | 2014-05-28 | 2018-04-27 | Childrens Hospital Med Ct | Methods and systems for converting precursor cells into gastric tissues through directed differentiation |
| AU2015331848B2 (en) | 2014-10-17 | 2022-03-03 | Children's Hospital Medical Center, D/B/A Cincinnati Children's Hospital Medical Center | In vivo model of human small intestine using pluripotent stem cells and methods of making and using same |
| US10627415B2 (en) | 2015-03-12 | 2020-04-21 | Board Of Trustees Of Michigan State University | Compositions and methods for diagnosing, monitoring, and treating an autoimmune disease |
| CN109415685B (zh) * | 2016-05-05 | 2023-07-04 | 儿童医院医疗中心 | 用于体外制造胃底组织的方法和与其相关的组合物 |
| WO2017206837A1 (zh) * | 2016-06-03 | 2017-12-07 | 中国人民解放军军事医学科学院野战输血研究所 | 将消化道来源上皮细胞重编程为内胚层干/祖细胞的小分子化合物组合、重编程方法及应用 |
| EP3534976A4 (en) | 2016-11-04 | 2020-09-16 | Children's Hospital Medical Center | PATHOLOGICAL MODELS OF HEPATIC ORGANOIDS AND ASSOCIATED METHODS OF MANUFACTURE AND USE |
| CA3045145A1 (en) | 2016-12-05 | 2018-06-14 | Children's Hospital Medical Center | Colonic organoids and methods of making and using same |
| US11530388B2 (en) * | 2017-02-14 | 2022-12-20 | University of Pittsburgh—of the Commonwealth System of Higher Education | Methods of engineering human induced pluripotent stem cells to produce liver tissue |
| US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
| WO2018191673A1 (en) | 2017-04-14 | 2018-10-18 | Children's Hospital Medical Center | Multi donor stem cell compositions and methods of making same |
| JP2020536529A (ja) * | 2017-10-10 | 2020-12-17 | チルドレンズ ホスピタル メディカル センター | 食道組織および／または臓器組成物およびそれを作製する方法 |
| WO2019126626A1 (en) | 2017-12-21 | 2019-06-27 | Children's Hospital Medical Center | Digitalized human organoids and methods of using same |
| SG11202009855WA (en) * | 2018-04-23 | 2020-11-27 | Univ Kyoto | Growth inhibitor |
| EP3826652B1 (en) | 2018-07-26 | 2026-02-25 | Children's Hospital Medical Center | Hepato-biliary-pancreatic tissues and methods of making same |
| EP3849568A4 (en) | 2018-09-12 | 2022-06-15 | Children's Hospital Medical Center | Organoid compositions for the production of hematopoietic stem cells and derivatives thereof |
| CN111394297A (zh) * | 2018-12-17 | 2020-07-10 | 中国科学院分子细胞科学卓越创新中心 | 内胚层干细胞规模化制备功能性肝母细胞与肝实质细胞的方法及其应用 |
| CA3138348A1 (en) * | 2019-05-09 | 2020-11-12 | FUJIFILM Cellular Dynamics, Inc. | Methods for the production of hepatocytes |
| AU2020283048A1 (en) | 2019-05-31 | 2021-12-23 | Children's Hospital Medical Center | Shaped organoid compositions and methods of making same |
| EP3976066A4 (en) | 2019-05-31 | 2023-06-28 | Children's Hospital Medical Center | Methods of generating and expanding hematopoietic stem cells |
| EP3980527A4 (en) * | 2019-06-04 | 2023-09-27 | University Health Network | Methods of making and using liver cells |
| CN113265373A (zh) * | 2021-07-19 | 2021-08-17 | 北京明诚创新医学研究院有限责任公司 | 一种人多能干细胞分化为肝祖细胞的培养基、方法及其应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9700983D0 (sv) * | 1997-03-18 | 1997-03-18 | Ascendia Ab | Stimulering, odling och preservation av pankreas- och andra celler |
| US20060003446A1 (en) * | 2002-05-17 | 2006-01-05 | Gordon Keller | Mesoderm and definitive endoderm cell populations |
| BRPI0617085A2 (pt) * | 2005-09-02 | 2016-11-08 | Agency Science Tech & Res | método para obter uma célula-tronco mesenquimal (msc), célula ou linhagem celular, método para derivar uma cultura celular a partir de uma célula-tronco embrionária, método para tratamento de uma doença, uso de uma célula-tronco mesenquimal, linhagem diferenciada, composição farmacêutica, método para condicionar um meio de cultura celular, meio condicionado e uso do mesmo, mpetodo para obterum polipeptídeo, método para obtar uma cultura celular, cultura celular, célula-tronco mesenquimal, linhagem de célula-tronco mesenquimal ou uma célula mesenquimal diferenciada |
| JP2009511061A (ja) * | 2005-10-14 | 2009-03-19 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | 膵臓表現型を有する細胞への非胚性幹細胞の分化 |
| US7989204B2 (en) * | 2006-04-28 | 2011-08-02 | Viacyte, Inc. | Hepatocyte lineage cells |
| US20090298169A1 (en) * | 2006-06-02 | 2009-12-03 | The University Of Georgia Research Foundation | Pancreatic and Liver Endoderm Cells and Tissue by Differentiation of Definitive Endoderm Cells Obtained from Human Embryonic Stems |
| US9029147B2 (en) * | 2007-06-15 | 2015-05-12 | Massachusetts Institute Of Technology | Methods and compositions for enhanced differentiation from embryonic stem cells |
| KR101555824B1 (ko) * | 2007-07-18 | 2015-09-25 | 라이프스캔, 인코포레이티드 | 인간 배아 줄기 세포의 분화 |
| EP2179034A1 (en) * | 2007-07-20 | 2010-04-28 | Cellartis AB | A novel population of hepatocytes derived via definitive endoderm (de-hep) from human blastocysts stem cells |
| WO2009137844A2 (en) * | 2008-05-09 | 2009-11-12 | Vistagen Therapeutics, Inc. | Pancreatic endocrine progenitor cells derived from pluripotent stem cells |
| WO2010127367A2 (en) * | 2009-05-01 | 2010-11-04 | Alfagene Bioscience, Inc. | Human gastrointestinal stem cell-derived primary intestinal epithelial cell system and methods of use thereof |
| WO2011005326A1 (en) * | 2009-07-09 | 2011-01-13 | Massachusetts Institute Of Technology | Methods and compositions for increased safety of stem cell-derived populations |
| JP5936547B2 (ja) * | 2009-10-30 | 2016-06-22 | ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | 肝外胆樹からの多能性幹細胞およびそれらを単離する方法 |
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2012
- 2012-06-25 CA CA2840192A patent/CA2840192A1/en not_active Abandoned
- 2012-06-25 JP JP2014517255A patent/JP2014519854A/ja active Pending
- 2012-06-25 WO PCT/US2012/044096 patent/WO2012178215A1/en not_active Ceased
- 2012-06-25 EP EP12802203.5A patent/EP2723851A4/en not_active Withdrawn
- 2012-06-25 AU AU2012272586A patent/AU2012272586B2/en not_active Ceased
-
2013
- 2013-12-23 US US14/138,963 patent/US9476030B2/en not_active Expired - Fee Related