JP2014519854A - ヒト多能性幹細胞から生じる自己複製する内胚葉前駆細胞株とその使用方法 - Google Patents

ヒト多能性幹細胞から生じる自己複製する内胚葉前駆細胞株とその使用方法 Download PDF

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JP2014519854A
JP2014519854A JP2014517255A JP2014517255A JP2014519854A JP 2014519854 A JP2014519854 A JP 2014519854A JP 2014517255 A JP2014517255 A JP 2014517255A JP 2014517255 A JP2014517255 A JP 2014517255A JP 2014519854 A JP2014519854 A JP 2014519854A
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endoderm
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ガデュー、ポール
フレンチ、デボラ
チェン、シン
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ザ チルドレンズ ホスピタル オブ フィラデルフィア
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JP2014517255A 2011-06-23 2012-06-25 ヒト多能性幹細胞から生じる自己複製する内胚葉前駆細胞株とその使用方法 Pending JP2014519854A (ja)

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US201161500442P 2011-06-23 2011-06-23
US61/500,442 2011-06-23
PCT/US2012/044096 WO2012178215A1 (en) 2011-06-23 2012-06-25 Self-renewing endodermal progenitor lines generated from human pluripotent stem cells and methods of use thereof

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WO2019208505A1 (ja) * 2018-04-23 2019-10-31 国立大学法人京都大学 増殖抑制剤
JP2022534555A (ja) * 2019-05-09 2022-08-02 フジフィルム セルラー ダイナミクス，インコーポレイテッド ヘパトサイトの作製方法
JP2022535855A (ja) * 2019-06-04 2022-08-10 ユニバーシティー ヘルス ネットワーク 肝臓細胞を作製および使用する方法

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CN105121632B (zh) * 2013-02-18 2021-08-10 大学健康网络 由多能干细胞生成肝细胞和胆管细胞的方法
WO2014165663A1 (en) * 2013-04-03 2014-10-09 Cellular Dynamics International, Inc. Methods and compositions for culturing endoderm progenitor cells in suspension
ES2860423T3 (es) 2014-05-28 2021-10-05 Childrens Hospital Med Ct Métodos y sistemas para convertir células precursoras en tejidos gástricos mediante diferenciación dirigida
CA2963704A1 (en) 2014-10-17 2016-04-21 Children's Hospital Medical Center In vivo model of human small intestine using pluripotent stem cells and methods of making and using same
CA2979397A1 (en) 2015-03-12 2016-09-15 Board Of Trustees Of Michigan State University Compositions and methods for measuring c-peptide binding and diagnosing immune-mediated diseases
CN109415685B (zh) * 2016-05-05 2023-07-04 儿童医院医疗中心 用于体外制造胃底组织的方法和与其相关的组合物
EP3483262B1 (en) * 2016-06-03 2021-11-17 Institue of Transfusion Medicine, Academy of Military Medical Sciences, People's Liberation Army of China Small molecule compound combination for reprogramming digestive tract derived epithelial cells to endodermal stem/progenitor cells, reprogramming method and application
SG10202104575WA (en) 2016-11-04 2021-06-29 Childrens Hospital Med Ct Liver organoid compositions and methods of making and using same
CA3045145A1 (en) 2016-12-05 2018-06-14 Children's Hospital Medical Center Colonic organoids and methods of making and using same
AU2018220843B2 (en) * 2017-02-14 2023-09-21 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods of engineering human induced pluripotent stem cells to produce liver tissue
US10767164B2 (en) 2017-03-30 2020-09-08 The Research Foundation For The State University Of New York Microenvironments for self-assembly of islet organoids from stem cells differentiation
US12281334B2 (en) 2017-04-14 2025-04-22 Children's Hospital Medical Center Multi donor stem cell compositions and methods of making same
WO2019074793A1 (en) * 2017-10-10 2019-04-18 Children's Hospital Medical Center OESOPHAGIAN TISSUE COMPOSITIONS AND / OR ORGANOIDS AND METHODS OF MAKING SAME
US12379372B2 (en) 2017-12-21 2025-08-05 Children's Hospital Medical Center Digitalized human organoids and methods of using same
CA3106634A1 (en) 2018-07-26 2020-01-30 Children's Hospital Medical Center Hepato-biliary-pancreatic tissues and methods of making same
CN112823012A (zh) 2018-09-12 2021-05-18 儿童医院医学中心 用于产生造血干细胞及其衍生物的类器官组合物
CN111394297A (zh) * 2018-12-17 2020-07-10 中国科学院分子细胞科学卓越创新中心 内胚层干细胞规模化制备功能性肝母细胞与肝实质细胞的方法及其应用
WO2020160371A1 (en) 2019-02-01 2020-08-06 The University Of Hong Kong Innervated organoid compositions and methods of making same
US12534709B2 (en) 2019-05-31 2026-01-27 Children's Hospital Medical Center Shaped organoid compositions and methods of making same
CA3141807A1 (en) 2019-05-31 2020-12-03 Children's Hospital Medical Center Methods of generating and expanding hematopoietic stem cells
CN113265373A (zh) * 2021-07-19 2021-08-17 北京明诚创新医学研究院有限责任公司 一种人多能干细胞分化为肝祖细胞的培养基、方法及其应用

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WO2019208505A1 (ja) * 2018-04-23 2019-10-31 国立大学法人京都大学 増殖抑制剤
JPWO2019208505A1 (ja) * 2018-04-23 2020-05-28 国立大学法人京都大学 増殖抑制剤
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JP7788858B2 (ja) 2019-06-04 2025-12-19 ユニバーシティー ヘルス ネットワーク 肝臓細胞を作製および使用する方法

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WO2012178215A1 (en) 2012-12-27
CA2840192A1 (en) 2012-12-27
EP2723851A1 (en) 2014-04-30
AU2012272586B2 (en) 2016-07-07
EP2723851A4 (en) 2015-05-20
US20140141509A1 (en) 2014-05-22
US9476030B2 (en) 2016-10-25

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