JP2014519854A - ヒト多能性幹細胞から生じる自己複製する内胚葉前駆細胞株とその使用方法 - Google Patents

ヒト多能性幹細胞から生じる自己複製する内胚葉前駆細胞株とその使用方法 Download PDF

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JP2014519854A
JP2014519854A JP2014517255A JP2014517255A JP2014519854A JP 2014519854 A JP2014519854 A JP 2014519854A JP 2014517255 A JP2014517255 A JP 2014517255A JP 2014517255 A JP2014517255 A JP 2014517255A JP 2014519854 A JP2014519854 A JP 2014519854A
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endoderm
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ガデュー、ポール
フレンチ、デボラ
チェン、シン
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ザ チルドレンズ ホスピタル オブ フィラデルフィア
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JP2014517255A 2011-06-23 2012-06-25 ヒト多能性幹細胞から生じる自己複製する内胚葉前駆細胞株とその使用方法 Pending JP2014519854A (ja)

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US201161500442P 2011-06-23 2011-06-23
US61/500,442 2011-06-23
PCT/US2012/044096 WO2012178215A1 (en) 2011-06-23 2012-06-25 Self-renewing endodermal progenitor lines generated from human pluripotent stem cells and methods of use thereof

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JP2014519854A5 JP2014519854A5 (enExample) 2015-08-13

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WO2019208505A1 (ja) * 2018-04-23 2019-10-31 国立大学法人京都大学 増殖抑制剤
JP2022534555A (ja) * 2019-05-09 2022-08-02 フジフィルム セルラー ダイナミクス，インコーポレイテッド ヘパトサイトの作製方法
JP2022535855A (ja) * 2019-06-04 2022-08-10 ユニバーシティー ヘルス ネットワーク 肝臓細胞を作製および使用する方法

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SG10201803131TA (en) * 2013-02-18 2018-06-28 Univ Health Network Methods for generating hepatocytes and cholangiocytes from pluripotent stem cells
US10266807B2 (en) 2013-04-03 2019-04-23 FUJIFILM Cellular Dynamics, Inc. Methods and compositions for culturing endoderm progenitor cells in suspension
EP3712254A1 (en) 2014-05-28 2020-09-23 Children's Hospital Medical Center Methods and systems for converting precursor cells into gastric tissues through directed differentiation
CA2963704A1 (en) 2014-10-17 2016-04-21 Children's Hospital Medical Center In vivo model of human small intestine using pluripotent stem cells and methods of making and using same
WO2016145389A1 (en) * 2015-03-12 2016-09-15 Board Of Trustees Of Michigan State University Compositions and methods for measuring c-peptide binding and diagnosing immune-mediated diseases
EP4177335A1 (en) * 2016-05-05 2023-05-10 Children's Hospital Medical Center Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same
EP3483262B1 (en) * 2016-06-03 2021-11-17 Institue of Transfusion Medicine, Academy of Military Medical Sciences, People's Liberation Army of China Small molecule compound combination for reprogramming digestive tract derived epithelial cells to endodermal stem/progenitor cells, reprogramming method and application
SG11201903697WA (en) 2016-11-04 2019-05-30 Childrens Hospital Med Ct Liver organoid compositions and methods of making and using same
EP3548507A4 (en) 2016-12-05 2020-07-15 Children's Hospital Medical Center COLON ORGANOIDS AND PROCESSES FOR THE PREPARATION AND USE THEREOF
EP3583201B1 (en) * 2017-02-14 2024-01-17 University of Pittsburgh - Of the Commonwealth System of Higher Education Methods of engineering human induced pluripotent stem cells to produce liver tissue
US10767164B2 (en) 2017-03-30 2020-09-08 The Research Foundation For The State University Of New York Microenvironments for self-assembly of islet organoids from stem cells differentiation
EP3609997A4 (en) 2017-04-14 2021-03-03 Children's Hospital Medical Center COMPOSITIONS OF STEM CELLS FROM MULTIPLE DONOR CELLS AND THEIR PREPARATION PROCEDURES
US12297457B2 (en) 2017-10-10 2025-05-13 Children's Hospital Medical Center Esophageal tissue and/or organoid compositions and methods of making same
EP3727394A4 (en) 2017-12-21 2021-09-08 Children's Hospital Medical Center DIGITALIZED HUMAN ORGANOIDS AND METHOD OF USING THEREOF
US12421500B2 (en) 2018-07-26 2025-09-23 Children's Hospital Medical Center Hepato-biliary-pancreatic tissues and methods of making same
JP2021535753A (ja) 2018-09-12 2021-12-23 チルドレンズ ホスピタル メディカル センター 造血幹細胞およびその派生体の生成のためのオルガノイド組成物
CN111394297A (zh) * 2018-12-17 2020-07-10 中国科学院分子细胞科学卓越创新中心 内胚层干细胞规模化制备功能性肝母细胞与肝实质细胞的方法及其应用
WO2020160371A1 (en) 2019-02-01 2020-08-06 The University Of Hong Kong Innervated organoid compositions and methods of making same
CA3141814A1 (en) 2019-05-31 2020-12-03 Children's Hospital Medical Center Shaped organoid compositions and methods of making same
CN114174494A (zh) 2019-05-31 2022-03-11 儿童医院医学中心 产生和扩增造血干细胞的方法
CN113265373A (zh) * 2021-07-19 2021-08-17 北京明诚创新医学研究院有限责任公司 一种人多能干细胞分化为肝祖细胞的培养基、方法及其应用

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WO2019208505A1 (ja) * 2018-04-23 2019-10-31 国立大学法人京都大学 増殖抑制剤
JPWO2019208505A1 (ja) * 2018-04-23 2020-05-28 国立大学法人京都大学 増殖抑制剤
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JP7788858B2 (ja) 2019-06-04 2025-12-19 ユニバーシティー ヘルス ネットワーク 肝臓細胞を作製および使用する方法

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WO2012178215A1 (en) 2012-12-27
EP2723851A1 (en) 2014-04-30
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US9476030B2 (en) 2016-10-25
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