JP2017500584A5 - - Google Patents
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- JP2017500584A5 JP2017500584A5 JP2016549205A JP2016549205A JP2017500584A5 JP 2017500584 A5 JP2017500584 A5 JP 2017500584A5 JP 2016549205 A JP2016549205 A JP 2016549205A JP 2016549205 A JP2016549205 A JP 2016549205A JP 2017500584 A5 JP2017500584 A5 JP 2017500584A5
- Authority
- JP
- Japan
- Prior art keywords
- assay
- biological sample
- hmwk
- autoimmune disease
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 238000000034 method Methods 0.000 claims 31
- 102000002261 High-Molecular-Weight Kininogen Human genes 0.000 claims 21
- 108010000487 High-Molecular-Weight Kininogen Proteins 0.000 claims 21
- 239000012472 biological sample Substances 0.000 claims 20
- 208000023275 Autoimmune disease Diseases 0.000 claims 16
- 238000003556 assay Methods 0.000 claims 12
- 239000000523 sample Substances 0.000 claims 7
- 238000002965 ELISA Methods 0.000 claims 6
- 239000011230 binding agent Substances 0.000 claims 6
- 206010009900 Colitis ulcerative Diseases 0.000 claims 4
- 208000011231 Crohn disease Diseases 0.000 claims 4
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 4
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 4
- 238000001514 detection method Methods 0.000 claims 3
- 229940042399 direct acting antivirals protease inhibitors Drugs 0.000 claims 3
- 238000003119 immunoblot Methods 0.000 claims 3
- 239000003112 inhibitor Substances 0.000 claims 3
- 239000000137 peptide hydrolase inhibitor Substances 0.000 claims 3
- 210000002966 serum Anatomy 0.000 claims 3
- 238000001262 western blot Methods 0.000 claims 3
- 102000003827 Plasma Kallikrein Human genes 0.000 claims 2
- 108090000113 Plasma Kallikrein Proteins 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 239000013068 control sample Substances 0.000 claims 1
- 230000007423 decrease Effects 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 229940126155 plasma kallikrein inhibitor Drugs 0.000 claims 1
- 230000002250 progressing effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361893542P | 2013-10-21 | 2013-10-21 | |
| US61/893,542 | 2013-10-21 | ||
| PCT/US2014/061242 WO2015061182A1 (en) | 2013-10-21 | 2014-10-17 | Diagnosis and treatment of autoimmune diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020018129A Division JP7157089B2 (ja) | 2013-10-21 | 2020-02-05 | 自己免疫疾患の診断と治療 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017500584A JP2017500584A (ja) | 2017-01-05 |
| JP2017500584A5 true JP2017500584A5 (cg-RX-API-DMAC7.html) | 2017-11-30 |
| JP6657098B2 JP6657098B2 (ja) | 2020-03-04 |
Family
ID=52993412
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016549205A Active JP6657098B2 (ja) | 2013-10-21 | 2014-10-17 | 自己免疫疾患の診断と治療 |
| JP2020018129A Active JP7157089B2 (ja) | 2013-10-21 | 2020-02-05 | 自己免疫疾患の診断と治療 |
| JP2022161469A Active JP7541560B2 (ja) | 2013-10-21 | 2022-10-06 | 自己免疫疾患の診断と治療 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020018129A Active JP7157089B2 (ja) | 2013-10-21 | 2020-02-05 | 自己免疫疾患の診断と治療 |
| JP2022161469A Active JP7541560B2 (ja) | 2013-10-21 | 2022-10-06 | 自己免疫疾患の診断と治療 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US10101344B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP3913364A1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP6657098B2 (cg-RX-API-DMAC7.html) |
| KR (3) | KR102485948B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN110658337B (cg-RX-API-DMAC7.html) |
| AU (4) | AU2014340449B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112016008975B1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2927695C (cg-RX-API-DMAC7.html) |
| DK (1) | DK3060908T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2873204T3 (cg-RX-API-DMAC7.html) |
| IL (4) | IL284969B (cg-RX-API-DMAC7.html) |
| PL (1) | PL3060908T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT3060908T (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015061182A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3456744B1 (en) * | 2013-01-20 | 2023-03-29 | Takeda Pharmaceutical Company Limited | Evaluation and treatment of bradykinin-mediated disorders |
| US10101344B2 (en) * | 2013-10-21 | 2018-10-16 | Dyax Corp. | Diagnosis and treatment of autoimmune diseases |
| AU2014340450B2 (en) | 2013-10-21 | 2020-05-21 | Takeda Pharmaceutical Company Limited | Assays for determining plasma kallikrein system biomarkers |
| PL3365685T3 (pl) * | 2015-10-19 | 2021-08-02 | Dyax Corp. | Test immunologiczny do wykrywania rozszczepionego wielkocząsteczkowego kininogenu |
| IL265195B2 (en) * | 2016-09-16 | 2025-02-01 | Dyax Corp | Protein biomarkers for diseases related to the activation system |
| KR200490846Y1 (ko) | 2019-04-09 | 2020-01-13 | 이대호 | 각도조절 브라켓 |
| KR20230050770A (ko) | 2021-10-08 | 2023-04-17 | 김경민 | 발로 열 수 있는 반려동물 울타리 |
| JP2025522757A (ja) * | 2022-06-30 | 2025-07-17 | 武田薬品工業株式会社 | ラナデルマブ治療のためのタンパク質バイオマーカー |
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| AU2014340450B2 (en) | 2013-10-21 | 2020-05-21 | Takeda Pharmaceutical Company Limited | Assays for determining plasma kallikrein system biomarkers |
| US10101344B2 (en) | 2013-10-21 | 2018-10-16 | Dyax Corp. | Diagnosis and treatment of autoimmune diseases |
| EA038532B1 (ru) | 2014-01-21 | 2021-09-10 | Такеда Фармасьютикал Компани Лимитед | Способ лечения наследственного ангионевротического отека (hae) |
| PL3365685T3 (pl) | 2015-10-19 | 2021-08-02 | Dyax Corp. | Test immunologiczny do wykrywania rozszczepionego wielkocząsteczkowego kininogenu |
| AU2016372159B2 (en) | 2015-12-15 | 2022-03-24 | Takeda Pharmaceutical Company Limited | Peptide quantitation assay for differentiating full-length high molecular weight kininogen (HMWK) and cleaved HMWK |
| WO2021154992A1 (en) * | 2020-01-28 | 2021-08-05 | Orgenesis Inc. | Process and system for acellular therapy |
-
2014
- 2014-10-17 US US15/030,790 patent/US10101344B2/en active Active
- 2014-10-17 IL IL284969A patent/IL284969B/en unknown
- 2014-10-17 KR KR1020217026950A patent/KR102485948B1/ko active Active
- 2014-10-17 ES ES14855002T patent/ES2873204T3/es active Active
- 2014-10-17 JP JP2016549205A patent/JP6657098B2/ja active Active
- 2014-10-17 WO PCT/US2014/061242 patent/WO2015061182A1/en not_active Ceased
- 2014-10-17 DK DK14855002.3T patent/DK3060908T3/da active
- 2014-10-17 KR KR1020167013312A patent/KR102295623B1/ko active Active
- 2014-10-17 PT PT148550023T patent/PT3060908T/pt unknown
- 2014-10-17 EP EP21158440.4A patent/EP3913364A1/en active Pending
- 2014-10-17 IL IL293948A patent/IL293948A/en unknown
- 2014-10-17 PL PL14855002T patent/PL3060908T3/pl unknown
- 2014-10-17 CA CA2927695A patent/CA2927695C/en active Active
- 2014-10-17 EP EP14855002.3A patent/EP3060908B1/en active Active
- 2014-10-17 CN CN201910994046.2A patent/CN110658337B/zh active Active
- 2014-10-17 CN CN201480069823.8A patent/CN105874332B/zh active Active
- 2014-10-17 KR KR1020237000230A patent/KR102665705B1/ko active Active
- 2014-10-17 AU AU2014340449A patent/AU2014340449B2/en active Active
- 2014-10-17 BR BR112016008975-8A patent/BR112016008975B1/pt active IP Right Grant
-
2016
- 2016-04-19 IL IL245206A patent/IL245206B/en active IP Right Grant
-
2018
- 2018-09-14 US US16/131,781 patent/US10648990B2/en active Active
-
2020
- 2020-01-21 AU AU2020200423A patent/AU2020200423B2/en active Active
- 2020-02-05 JP JP2020018129A patent/JP7157089B2/ja active Active
- 2020-04-15 US US16/849,492 patent/US12061206B2/en active Active
- 2020-06-14 IL IL275368A patent/IL275368B/en unknown
-
2022
- 2022-06-29 AU AU2022204649A patent/AU2022204649B2/en active Active
- 2022-10-06 JP JP2022161469A patent/JP7541560B2/ja active Active
-
2024
- 2024-11-19 AU AU2024266697A patent/AU2024266697A1/en active Pending
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