JP2017500020A5 - - Google Patents
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- JP2017500020A5 JP2017500020A5 JP2016533175A JP2016533175A JP2017500020A5 JP 2017500020 A5 JP2017500020 A5 JP 2017500020A5 JP 2016533175 A JP2016533175 A JP 2016533175A JP 2016533175 A JP2016533175 A JP 2016533175A JP 2017500020 A5 JP2017500020 A5 JP 2017500020A5
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- JP
- Japan
- Prior art keywords
- primer
- region
- item
- nucleotide
- template
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108091033319 polynucleotide Proteins 0.000 claims description 119
- 102000040430 polynucleotide Human genes 0.000 claims description 119
- 239000002157 polynucleotide Substances 0.000 claims description 119
- 230000000295 complement effect Effects 0.000 claims description 92
- 238000000034 method Methods 0.000 claims description 73
- 239000011541 reaction mixture Substances 0.000 claims description 51
- 230000003321 amplification Effects 0.000 claims description 6
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 6
- 238000005382 thermal cycling Methods 0.000 claims description 4
- 239000002773 nucleotide Substances 0.000 description 332
- 125000003729 nucleotide group Chemical group 0.000 description 332
- 102000039446 nucleic acids Human genes 0.000 description 84
- 108020004707 nucleic acids Proteins 0.000 description 84
- 150000007523 nucleic acids Chemical class 0.000 description 84
- 238000011144 upstream manufacturing Methods 0.000 description 11
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 description 8
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 description 8
- 102100034343 Integrase Human genes 0.000 description 7
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 description 7
- 238000006073 displacement reaction Methods 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
- 238000011534 incubation Methods 0.000 description 7
- 108020004414 DNA Proteins 0.000 description 6
- 102000053602 DNA Human genes 0.000 description 6
- 239000000980 acid dye Substances 0.000 description 5
- 108091032973 (ribonucleotides)n+m Proteins 0.000 description 4
- 108091028043 Nucleic acid sequence Proteins 0.000 description 4
- 239000012472 biological sample Substances 0.000 description 4
- 238000004891 communication Methods 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 108020004635 Complementary DNA Proteins 0.000 description 1
- 108091028732 Concatemer Proteins 0.000 description 1
- JCAQMQLAHNGVPY-UUOKFMHZSA-N [(2r,3s,4r,5r)-3,4-dihydroxy-5-(2,2,4-trioxo-1h-imidazo[4,5-c][1,2,6]thiadiazin-7-yl)oxolan-2-yl]methyl dihydrogen phosphate Chemical group O[C@@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N1C(NS(=O)(=O)NC2=O)=C2N=C1 JCAQMQLAHNGVPY-UUOKFMHZSA-N 0.000 description 1
- 238000010306 acid treatment Methods 0.000 description 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361908027P | 2013-11-22 | 2013-11-22 | |
| US61/908,027 | 2013-11-22 | ||
| USPCT/US2014/030034 | 2014-03-15 | ||
| US14/214,850 US9725760B2 (en) | 2013-03-15 | 2014-03-15 | Nucleic acid amplification |
| US14/214,850 | 2014-03-15 | ||
| PCT/US2014/030034 WO2014145296A2 (en) | 2013-03-15 | 2014-03-15 | Nuclei acid amplification |
| US201462001050P | 2014-05-20 | 2014-05-20 | |
| US62/001,050 | 2014-05-20 | ||
| PCT/US2014/056151 WO2015076919A1 (en) | 2013-11-22 | 2014-09-17 | Nucleic Acid Amplification |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019163192A Division JP2019201670A (ja) | 2013-11-22 | 2019-09-06 | 核酸増幅 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017500020A JP2017500020A (ja) | 2017-01-05 |
| JP2017500020A5 true JP2017500020A5 (cg-RX-API-DMAC7.html) | 2017-11-02 |
Family
ID=53179994
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016533175A Withdrawn JP2017500020A (ja) | 2013-11-22 | 2014-09-17 | 核酸増幅 |
| JP2019163192A Pending JP2019201670A (ja) | 2013-11-22 | 2019-09-06 | 核酸増幅 |
| JP2022145326A Pending JP2022172384A (ja) | 2013-11-22 | 2022-09-13 | 核酸増幅 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019163192A Pending JP2019201670A (ja) | 2013-11-22 | 2019-09-06 | 核酸増幅 |
| JP2022145326A Pending JP2022172384A (ja) | 2013-11-22 | 2022-09-13 | 核酸増幅 |
Country Status (12)
| Country | Link |
|---|---|
| EP (2) | EP3071713B1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP2017500020A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20160088316A (cg-RX-API-DMAC7.html) |
| CN (2) | CN106255763B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2014353462A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112016011692A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2927315A1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2879823T3 (cg-RX-API-DMAC7.html) |
| HK (1) | HK1232259A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL245687A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MX370616B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015076919A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2014233213A1 (en) * | 2013-03-15 | 2015-09-17 | Theranos Ip Company, Llc | Thermostable blunt-end ligase and methods of use |
| EP3194590A4 (en) * | 2014-09-17 | 2018-05-09 | Theranos, Inc. | Hybrid multi-step nucleic acid amplification |
| US10822648B1 (en) | 2016-07-29 | 2020-11-03 | Labrador Diagnostics Llc | Hybrid multi-step nucleic acid amplification |
| CN110819738A (zh) * | 2019-11-20 | 2020-02-21 | 拱北海关技术中心 | 高致病性h7n9禽流感病毒的检测方法及其引物和探针 |
| AU2021366658A1 (en) * | 2020-10-21 | 2023-06-22 | Illumina Cambridge Limited | Sequencing templates comprising multiple inserts and compositions and methods for improving sequencing throughput |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5928905A (en) * | 1995-04-18 | 1999-07-27 | Glaxo Group Limited | End-complementary polymerase reaction |
| BR0014182A (pt) * | 1999-09-13 | 2002-05-21 | Nugen Technologies Inc | Processos e composições para amplificação isotérmica linear de sequências polinucleotìdicas |
| DE60141087D1 (de) * | 2000-06-26 | 2010-03-04 | Nugen Technologies Inc | Methoden und zusammensetzungen zur auf transkription basierenden vervielfältigung von nukleinsäuren |
| JP4280519B2 (ja) * | 2003-03-07 | 2009-06-17 | アークレイ株式会社 | Ｄｎａ増幅法およびそのためのキット |
| GB0504774D0 (en) * | 2005-03-08 | 2005-04-13 | Lingvitae As | Method |
| GB0618046D0 (en) * | 2006-09-13 | 2006-10-25 | Lingvitae As | Method |
| WO2008070352A2 (en) * | 2006-10-27 | 2008-06-12 | Complete Genomics, Inc. | Efficient arrays of amplified polynucleotides |
| GB0910302D0 (en) * | 2009-06-15 | 2009-07-29 | Lumora Ltd | Nucleic acid amplification |
| CN101935697B (zh) * | 2010-04-16 | 2015-11-25 | 中生方政生物技术有限公司 | 用于核酸序列检测的方法和试剂盒 |
| JP5299981B1 (ja) * | 2011-09-08 | 2013-09-25 | 独立行政法人理化学研究所 | プライマーセット及びそれを用いた標的核酸配列の増幅方法並びに変異核酸の検出方法 |
-
2014
- 2014-09-17 EP EP14864826.4A patent/EP3071713B1/en active Active
- 2014-09-17 JP JP2016533175A patent/JP2017500020A/ja not_active Withdrawn
- 2014-09-17 CN CN201480073710.5A patent/CN106255763B/zh active Active
- 2014-09-17 AU AU2014353462A patent/AU2014353462A1/en not_active Abandoned
- 2014-09-17 KR KR1020167013498A patent/KR20160088316A/ko not_active Withdrawn
- 2014-09-17 BR BR112016011692A patent/BR112016011692A2/pt not_active Application Discontinuation
- 2014-09-17 MX MX2016006602A patent/MX370616B/es active IP Right Grant
- 2014-09-17 CA CA2927315A patent/CA2927315A1/en not_active Abandoned
- 2014-09-17 CN CN202210640563.1A patent/CN114807321A/zh active Pending
- 2014-09-17 WO PCT/US2014/056151 patent/WO2015076919A1/en not_active Ceased
- 2014-09-17 ES ES14864826T patent/ES2879823T3/es active Active
- 2014-09-17 HK HK17105960.6A patent/HK1232259A1/zh unknown
- 2014-09-17 EP EP21173022.1A patent/EP3957741A1/en not_active Withdrawn
-
2016
- 2016-05-17 IL IL245687A patent/IL245687A0/en unknown
-
2019
- 2019-09-06 JP JP2019163192A patent/JP2019201670A/ja active Pending
-
2022
- 2022-09-13 JP JP2022145326A patent/JP2022172384A/ja active Pending
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