JP2017008079A5 - - Google Patents

Download PDF

Info

Publication number
JP2017008079A5
JP2017008079A5 JP2016158397A JP2016158397A JP2017008079A5 JP 2017008079 A5 JP2017008079 A5 JP 2017008079A5 JP 2016158397 A JP2016158397 A JP 2016158397A JP 2016158397 A JP2016158397 A JP 2016158397A JP 2017008079 A5 JP2017008079 A5 JP 2017008079A5
Authority
JP
Japan
Prior art keywords
group
ester
pharmaceutically acceptable
acceptable salt
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016158397A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017008079A (ja
JP6223514B2 (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2017008079A publication Critical patent/JP2017008079A/ja
Publication of JP2017008079A5 publication Critical patent/JP2017008079A5/ja
Application granted granted Critical
Publication of JP6223514B2 publication Critical patent/JP6223514B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2016158397A 2011-01-28 2016-08-12 縮環化合物 Expired - Fee Related JP6223514B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2011016950 2011-01-28
JP2011016950 2011-01-28

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2012554878A Division JP5990106B2 (ja) 2011-01-28 2012-01-30 縮環化合物

Publications (3)

Publication Number Publication Date
JP2017008079A JP2017008079A (ja) 2017-01-12
JP2017008079A5 true JP2017008079A5 (enExample) 2017-03-16
JP6223514B2 JP6223514B2 (ja) 2017-11-01

Family

ID=46580968

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2012554878A Expired - Fee Related JP5990106B2 (ja) 2011-01-28 2012-01-30 縮環化合物
JP2016158397A Expired - Fee Related JP6223514B2 (ja) 2011-01-28 2016-08-12 縮環化合物

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2012554878A Expired - Fee Related JP5990106B2 (ja) 2011-01-28 2012-01-30 縮環化合物

Country Status (5)

Country Link
US (2) US8987473B2 (enExample)
EP (1) EP2669270B1 (enExample)
JP (2) JP5990106B2 (enExample)
DK (1) DK2669270T3 (enExample)
WO (1) WO2012102405A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2794561B1 (en) * 2011-12-21 2018-08-22 Allergan, Inc. Compounds acting at multiple prostaglandin receptors giving a general anti-inflammatory response
EP3444238B1 (en) 2012-07-27 2021-12-08 Sato Pharmaceutical Co., Ltd. Process for preparing difluoromethylene compounds
CN102875590A (zh) * 2012-10-22 2013-01-16 北京林业大学 芳香族三丁基锡衍生物的制备方法
SG11201706869XA (en) * 2015-03-24 2017-09-28 Shanghai Yingli Pharm Co Ltd Condensed ring derivative, and preparation method, intermediate, pharmaceutical composition and use thereof
RU2750151C2 (ru) 2015-11-20 2021-06-22 Форма Терапьютикс, Инк. Гипоксантины в качестве ингибиторов убиквитин-специфической протеазы 1
CN106045898B (zh) * 2016-06-28 2019-05-24 广东东阳光药业有限公司 一种吲哚类化合物及其制备方法和用途
CN106146533B (zh) * 2016-07-14 2018-04-03 华润赛科药业有限责任公司 含硫杂环羧酸类衍生物、其制备方法和应用
EP3538151B1 (en) 2016-11-11 2024-06-26 Whitehead Institute for Biomedical Research Human plasma-like medium
US11447503B2 (en) 2019-06-14 2022-09-20 Janssen Pharmaceutica Nv Pyridine carbamates and their use as GLUN2B receptor modulators
TWI774755B (zh) * 2017-04-28 2022-08-21 日商佐藤製藥股份有限公司 二氟甲烯化合物之製造法
RU2019144010A (ru) 2017-06-08 2021-07-13 Мерк Шарп И Доум Корп. Пиразолопиримидиновые ингибиторы pde9
US20200172483A1 (en) * 2017-06-22 2020-06-04 Curadev Pharma Limited Heterocyclic small molecule modulators of human sting
HUE066335T2 (hu) 2018-10-05 2024-07-28 Annapurna Bio Inc Vegyületek és készítmények APJ receptor aktivitáshoz kapcsolódó állapotok kezelésére
US11459336B2 (en) 2019-06-14 2022-10-04 Janssen Pharmaceutica Nv Pyrazine carbamates and their use as GluN2B receptor modulators
KR20220024403A (ko) 2019-06-14 2022-03-03 얀센 파마슈티카 엔.브이. 치환된 피라졸로-피라진 및 이들의 glun2b 수용체 조절제로서의 용도
BR112021025141A2 (pt) 2019-06-14 2022-01-25 Janssen Pharmaceutica Nv Pirazolo-piridinas heteroaromáticas substituídas e seu uso como moduladores do receptor glun2b
EP3983075A1 (en) * 2019-06-14 2022-04-20 Janssen Pharmaceutica NV Substituted pyrazolo-pyridine amides and their use as glun2b receptor modulators
GB202013728D0 (en) * 2020-09-01 2020-10-14 Nrg Therapeutics Ltd Novel compounds
CA3196620A1 (en) 2020-10-05 2022-04-14 Enliven Therapeutics, Inc. 5- and 6-azaindole compounds for inhibition of bcr-abl tyrosine kinases
PT4426434T (pt) 2021-11-02 2025-11-24 Flare Therapeutics Inc Agonistas inversos de pparg e suas utilizações
JP7792730B2 (ja) * 2022-04-27 2025-12-26 杭州新元素▲薬▼▲業▼有限公司 尿酸を降下させるために使用できる化合物
WO2026008750A1 (en) 2024-07-05 2026-01-08 Syngenta Crop Protection Ag Novel carboxamide compounds

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0470543A1 (de) * 1990-08-10 1992-02-12 Dr. Karl Thomae GmbH Heterocyclische Imidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zur ihrer Herstellung
GB9121776D0 (en) * 1991-10-14 1991-11-27 Fujisawa Pharmaceutical Co Benzimidazole derivatives and process for preparation thereof
WO1996003377A1 (en) * 1994-07-27 1996-02-08 Sankyo Company, Limited Heterocyclic compounds, useful as allosteric effectors at muscarinic receptors
KR100430059B1 (ko) * 1995-04-10 2004-09-24 후지사와 야꾸힝 고교 가부시키가이샤 cGMP-PDE억제제로서의인돌유도체
WO1997003473A1 (fr) 1995-07-10 1997-01-30 International Business Machines Corporation Dispositif de boitier pour bloc batterie et bloc batterie
HUP9900625A3 (en) * 1995-12-28 2003-04-28 Fujisawa Pharmaceutical Co Benzimidazole derivatives, pharmaceutical compositions containing them and process for preparing the compounds
AUPO118896A0 (en) * 1996-07-23 1996-08-15 Fujisawa Pharmaceutical Co., Ltd. New use
AU3899097A (en) * 1996-08-05 1998-02-25 Rhone-Poulenc Rorer Pharmaceuticals Inc. Substituted aromatic compounds
AU4400597A (en) * 1996-10-08 1998-05-05 Fujisawa Pharmaceutical Co., Ltd. Indole derivatives
JPH10114654A (ja) * 1996-10-09 1998-05-06 Fujisawa Pharmaceut Co Ltd 新規用途
TW453999B (en) * 1997-06-27 2001-09-11 Fujisawa Pharmaceutical Co Benzimidazole derivatives
WO1999000372A1 (fr) 1997-06-27 1999-01-07 Fujisawa Pharmaceutical Co., Ltd. Sulfamides et leur utilisation medicale
US6410584B1 (en) * 1998-01-14 2002-06-25 Cell Pathways, Inc. Method for inhibiting neoplastic cells with indole derivatives
US6358992B1 (en) * 1998-11-25 2002-03-19 Cell Pathways, Inc. Method of inhibiting neoplastic cells with indole derivatives
EP1142880A4 (en) 1998-12-24 2002-02-27 Fujisawa Pharmaceutical Co BENZIMIDAZOLE DERIVATIVES
DE60017446T2 (de) 1999-11-05 2006-03-02 Smithkline Beecham P.L.C., Brentford Isochinolin- und Chinazolinderivate mit kombinierter 5-HT1A-, 5-HT1B- und 5-HT1D- Rezeptoraffinität
EP1460067A4 (en) * 2001-11-26 2005-12-07 Takeda Pharmaceutical BICYCLIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE
AU2003902860A0 (en) 2003-06-06 2003-06-26 Daicel Chemical Industries, Ltd Benzimidazole compounds
AR051780A1 (es) * 2004-11-29 2007-02-07 Japan Tobacco Inc Compuestos en anillo fusionados que contienen nitrogeno y utilizacion de los mismos
EP1985297A1 (en) 2006-01-27 2008-10-29 Japan Tobacco, Inc. Carboxylic acid compound and use thereof
US20070197512A1 (en) 2006-01-27 2007-08-23 Japan Tobacco Inc. Carboxylic Acid Compounds and Use Thereof
CN101384550B (zh) 2006-02-20 2011-08-31 安斯泰来制药株式会社 酰胺衍生物或其盐
CA2644809A1 (en) 2006-03-02 2007-09-07 Astellas Pharma Inc. 17 .beta. hsd type 5 inhibitor
WO2007109178A2 (en) * 2006-03-16 2007-09-27 Pharmacyclics, Inc. Indole derivatives as inhibitors of histone deacetylase
NZ576278A (en) * 2006-10-19 2011-12-22 Signal Pharm Llc Heteroaryl compounds, compositions thereof, and their use as protein kinase inhibitors
CN101702905A (zh) * 2007-02-13 2010-05-05 先灵公司 功能选择性α2C肾上腺素能受体激动剂
BRPI0810524B8 (pt) 2007-04-11 2021-05-25 Kissei Pharmaceutical derivado de (aza)indol, inibidor de xantina oxidase e composição farmacêutica compreendendo o dito derivado
US9149463B2 (en) 2007-09-18 2015-10-06 The Board Of Trustees Of The Leland Standford Junior University Methods and compositions of treating a Flaviviridae family viral infection
MX2010009959A (es) 2008-03-13 2010-10-04 Wellstat Therapeutics Corp Compuestos y metodo para reducir el acido urico.
CA2875549A1 (en) * 2008-04-15 2009-10-22 Pharmacyclics, Inc. Selective inhibitors of histone deacetylase
KR101048448B1 (ko) * 2008-11-21 2011-07-11 한국화학연구원 신규 피라졸로[4,3-b]피리딘 유도체 또는 이의 약학적으로허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 약학적 조성물
US8975247B2 (en) * 2009-03-18 2015-03-10 The Board Of Trustees Of The Leland Stanford Junion University Methods and compositions of treating a flaviviridae family viral infection
JP2011246389A (ja) * 2010-05-26 2011-12-08 Oncotherapy Science Ltd Ttk阻害作用を有する縮環ピラゾール誘導体

Similar Documents

Publication Publication Date Title
JP2017008079A5 (enExample)
JP2017505762A5 (enExample)
JP2010507602A5 (enExample)
JP2018515525A5 (enExample)
JP2016520116A5 (enExample)
JP2017535561A5 (enExample)
JP2013528655A5 (enExample)
JP2016164184A5 (enExample)
JP2012524055A5 (enExample)
JP2019512535A5 (enExample)
JP2009533343A5 (enExample)
JP2011502958A5 (enExample)
JP2005521642A5 (enExample)
JP2011500545A5 (enExample)
JP2012525431A5 (enExample)
RU2018120242A (ru) Хинолиновые соединения, способы их получения и их применения в качестве лекарственного средства, ингибирующего транспортер уратов
TWI455939B (zh) cMET抑制劑
JP2009507896A5 (enExample)
JP2020516671A5 (enExample)
JP2004501930A5 (enExample)
JP2015500326A5 (enExample)
JP2011528658A5 (enExample)
JP2005500363A5 (enExample)
JP2013521288A5 (enExample)
RU2011143741A (ru) Производное индолизина и его применение в медицинских целях